The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Prospective, Randomized Study of Goal-Oriented Hemodynamic Therapy in Cardiac Surgical Patients
Abstract
UNLABELLED: Organ dysfunction and multiple organ failure are the main causes of prolonged hospital stay after cardiac surgery, which increases resource use and health care costs. Increased levels of oxygen delivery and consumption are associated with improved outcome in different groups of postoperative patients. Cardiac surgical patients are at risk of inadequate perioperative oxygen delivery caused by extracorporeal circulation and limited cardiovascular reserves. The purpose of our study was to test whether increasing oxygen delivery immediately after cardiac surgery would shorten hospital and intensive care unit (ICU) stay. Four hundred three elective cardiac surgical patients were enrolled in the study and randomly assigned to either the control or the protocol group. Goals of the protocol group were to maintain SvO(2) >70% and lactate concentration < or =2.0 mmol/L from admission to the ICU and up to 8 h thereafter. Hemodynamics, oxygen transport data, and organ dysfunctions were recorded. The median hospital stay was shorter in the protocol group (6 vs 7 days, P < 0.05), and patients were discharged faster from the hospital than those in the control group (P < 0.05). Discharge from the ICU was similar between groups (P = 0. 8). Morbidity was less frequent at the time of hospital discharge in the protocol group (1.1% vs 6.1%, P < 0.01). Increasing oxygen delivery to achieve normal SvO(2) values and lactate concentration during the immediate postoperative period after cardiac surgery can shorten the length of hospital stay. IMPLICATIONS: Health care economics has challenged clinicians to reduce costs and improve resource use in cardiac surgery and anesthesia in a patient population increasing in age and in severity of disease. Optimizing cardiovascular function to maintain adequate oxygen delivery during the immediate postoperative period after cardiac surgery can decrease morbidity and reduce length of hospital stay.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Determinants of duration of ICU stay after coronary artery bypass graft surgery
Michalopoulos, A., Tzelepis, G., Pavlides, G., Kriaras, J., Dafni, U., & Geroulanos, S. (1996) · British Journal of Anaesthesia · doi:10.1093/bja/77.2.208 · Cited by 55 · cited 1×
“ever, up to 10% of patients (1,2) need prolonged”
Background
Cited by
Jansen, T. C., van Bommel, J., Schoonderbeek, F. J., Sleeswijk Visser, S. J., van der Klooster, J. M., Lima, A. P., Willemsen, S. P., & Bakker, J. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200912-1918oc · Cited by 894
Clinical use of lactate monitoring in critically ill patients
Bakker, J., Nijsten, M. W., & Jansen, T. C. (2013) · Annals of Intensive Care · doi:10.1186/2110-5820-3-12 · Cited by 473
Low-Cardiac-Output Syndrome After Cardiac Surgery
Lomivorotov, V. V., Efremov, S. M., Kirov, M. Y., Fominskiy, E. V., & Karaskov, A. M. (2017) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2016.05.029 · Cited by 315
Jansen, T. C., van Bommel, J., Woodward, R., Mulder, P. G. H., & Bakker, J. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181a0f919 · Cited by 177
Yamazaki, Y., Oba, K., Matsui, Y., & Morimoto, Y. (2018) · Journal of Anesthesia · doi:10.1007/s00540-018-2447-2 · Cited by 137
Current use of the pulmonary artery catheter in cardiac surgery: a survey study
Judge, O., Ji, F., Fleming, N., & Liu, H. (2015) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2014.07.016 · Cited by 93
Determining the clinical value of lactate in surgical patients on the intensive care unit
Meyer, Z. C., Schreinemakers, J. M. J., Mulder, P. G. H., de Waal, R. A. L., Ermens, A. A. M., & van der Laan, L. (2013) · Journal of Surgical Research · doi:10.1016/j.jss.2013.02.048 · Cited by 16
Metadata
- Authors
- Pölönen, P., Ruokonen, E., Hippeläinen, M., Pöyhönen, M., & Takala, J.
- Venue
- Anesthesia & Analgesia
- Published
- 2000-05
- Volume
- 90
- Issue
- 5
- Pages
- 1052-1059
- ISSN
- 0003-2999 (ISSN-L)
- OpenAlex
- W2001646719
- Cited by
- 560
- References
- 1
- FWCI
- 9.90
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
