The use of testosterone propionate in the treatment of advanced carcinoma of the breast.

Adair, Frank E.; Herrmann, Julian B.

doi:10.1097/00000658-194606000-00006

Cited by 127Breast Cancer Treatment StudiesEstrogen and related hormone effectsMale Breast Health Studies

The use of testosterone propionate in the treatment of advanced carcinoma of the breast.

Adair, Frank E., Herrmann, Julian B.·1946·Annals of Surgery

DOI 10.1097/00000658-194606000-00006

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Many studies have confirmed beneficial effects of androgens on breast cancer.
“Many studies subsequently confirmed the beneficial effects of androgens on breast cancer (165, 167-174, 251, 252).”
From Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone (2003) · cites this paper as [251]

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Method
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Background
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“Hermann and Adair, 1947, 1946 [71,84] • Treatment of patients with breast cancer with testosterone propionate showed significant regression of cancer and disappearance of metastases.”
Background
THE USE OF ESTROGENS AND ANDROGENS IN ADVANCED MAMMARY CANCER
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“Patients with metastatic breast cancer received androgens in the first half of the 20th century, with response rates of 19%–36% (3,4).”
Background
The psychological impact of cancer and cancer surgery.I. Adaptation to the dry colostomy; preliminary report and summary of findings
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Background
Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial
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“(E) AR agonist DHT inhibits growth of HCI-13 PDX. HCI-13 PDX was performed as indicated above.”
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Authors: Adair, F. E., & Herrmann, J. B.
Venue: Annals of Surgery
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1946-06
Volume: 123
Issue: 6
Pages: 1023-1035
ISSN: 0003-4932 (ISSN-L)
DOI: 10.1097/00000658-194606000-00006
OpenAlex: W2065740173
Cited by: 127
References: 0
Citations by year: 2025: 3 · 2024: 1 · 2023: 1 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 9 · 2015: 5 · 2014: 2 · 2013: 2 · 2012: 3
FWCI: 15.11
Type: journal article
Language: en
Open access: closed
Locations: Annals of Surgery (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Male Breast Health Studies
Keywords: testosterone propionate, breast cancer, advanced breast cancer, androgen therapy, hormone therapy

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The use of testosterone propionate in the treatment of advanced carcinoma of the breast.

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