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Cited by 400

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Hepatic Resection for Hepatocellular Carcinoma An Audit of 343 Patients

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Lai, Edward C. S., Fan, Sheung-Tat, Lo, Chung-Mau, Chu, Kent-Man, Liu, Chi-Leung, Wong, John·1995·Annals of Surgery

Abstract

OBJECTIVE: The authors summarize the results of patients who had hepatectomy for hepatocellular carcinoma over a 22-year period. SUMMARY BACKGROUND DATA: Recent reports showed improved perioperative results and long-term prognosis. METHODS: The perioperative outcome of 343 patients was studied according to three different time periods: before 1987 (n = 149); 1987 to 1991 (n = 128); and 1992 to present (n = 66). Survival analysis was made by stratifying patients into two categories--either before or after 1987. The majority of patients had large tumors (78%), cirrhosis (73%), and a major hepatectomy (73%). RESULTS: Besides an increased resectability rate (23%), there was a marked reduction of the recent morbidity (32%; p < 0.001), operative (4.5%; NS) and hospital (6%; p < 0.02) mortality rates. The recent surgical approach was identified as a significant contributory factor to the lowered hospital mortality rate. Patients in the latter part of the study had significantly better survival, with a 1-, 3- and 5-year survival rate of 68%, 45%, and 35%, respectively. Early detection and effective treatment of recurrences contributed to the improved prognosis. CONCLUSIONS: The recent management strategy and technological advances improved the results of surgical treatment for patients with hepatocellular carcinoma.

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Metadata

Authors
Lai, E. C. S., Fan, S.-T., Lo, C.-M., Chu, K.-M., Liu, C.-L., & Wong, J.
Venue
Annals of Surgery
Published
1995-03
Volume
221
Issue
3
Pages
291-298
ISSN
0003-4932 (ISSN-L)
OpenAlex
W2062162459
Cited by
400
References
7
FWCI
10.13
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Hepatic Resection for Hepatocellular Carcinoma An Audit of 343 Patients. https://app.cochat.ai/papers/10.1097/00000658-199503000-00012
The paper
Lai, E. C. S., Fan, S.-T., Lo, C.-M., Chu, K.-M., Liu, C.-L., & Wong, J. (1995). Hepatic Resection for Hepatocellular Carcinoma An Audit of 343 Patients. Annals of Surgery. https://doi.org/10.1097/00000658-199503000-00012

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