Cited by 99Urinary Tract Infections ManagementUrinary Bladder and Prostate ResearchBacterial biofilms and quorum sensing

Prevention of catheter-associated urinary tract infection

Open access
Trautner, Barbara W, Hull, Richard A, Darouiche, Rabih O·2005·Current Opinion in Infectious Diseases

Abstract

PURPOSE OF REVIEW: The underlying cause of catheter-associated urinary tract infection is biofilm formation by uropathogens on the urinary catheter. Biofilm is a relatively new concept in medicine, and current measures to prevent biofilm formation are inadequate. Considerable work is being done in this area, but little clinical progress has been made. The purpose of this review is to analyze recent publications concerning prevention of catheter-associated urinary tract infection. RECENT FINDINGS: Several recent studies have elucidated aspects of biofilm formation in catheter-associated urinary tract infection. Other researchers are working on methods to disrupt biofilm formation on catheter surfaces. At the same time, the magnitude of the problem of catheter-associated urinary tract infection has increased awareness of the effectiveness of basic infection control measures. A modern approach to infection control may include computerized ordering systems that minimize unnecessary days of catheterization. Finally, consumption of cranberry juice products and bacterial interference are two novel approaches to urinary tract infection prevention. SUMMARY: Biofilm-disrupting strategies offer promise for the future but have little immediate applicability. Implementation of infection control measures to improve catheter function and remove unnecessary catheters can be done at the present time. In general, prevention of catheter-associated urinary tract infection remains an elusive goal. More basic research at the level of pathogenesis is needed so that novel strategies can be designed.

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Registry

Crossref · 10.1097/00001432-200502000-00007

Cites

47 of 47 references verified0 citation errors · 0 not checkable

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Authors
Trautner, B. W., Hull, R. A., & Darouiche, R. O.
Affiliations
Michael E. DeBakey VA Medical Center (US)
Corresponding author
Trautner, Barbara W
Venue
Current Opinion in Infectious Diseases
Published
2005-02
Volume
18
Issue
1
Pages
37-41
ISSN
0951-7375 (ISSN-L)
OpenAlex
W2111874187
Cited by
99
References
47
Citations by year
2025: 1 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 3 · 2017: 5 · 2016: 5 · 2015: 6 · 2014: 2 · 2013: 5 · 2012: 13
FWCI
0.94
Type
journal article
Language
en
Open access
Locations
  • Current Opinion in Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (K23HD042014, HD42014)
Topics
  • Health Sciences › Medicine › Epidemiology › Urinary Tract Infections Management
  • Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Keywords
catheter-associated urinary tract infection, biofilm formation, urinary catheter, uropathogens, biofilm eradication, infection control, cranberry juice, bacterial interference, catheter dwell time
MeSH terms
Catheters, Indwelling, Humans, Urinary Catheterization, Urinary Tract Infections, Infection Control, Biofilms

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