The DOI matches its Crossref record.
Macrophage Systems in Peripheral Nerves. A Review
Abstract
John W. Griffin, Rachel George, Tony Ho; Macrophage Systems in Peripheral Nerves. A Review, Journal of Neuropathology & Experimental Neurology, Volume 52, Issue
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Peripheral nerves have a variety of fibers with different physiology and function, as well as Schwann cells, blood vessels, and various supporting cells [42, 104–106].”
From Safety of long-term electrical peripheral nerve stimulation: review of the state of the art (2019) · cites this paper as [105]
Citations
Cited by
Sorted by citations
The cellular and molecular basis of peripheral nerve regeneration
Fu, S. Y., & Gordon, T. (1997) · Molecular Neurobiology · doi:10.1007/bf02740621 · Cited by 1,203
Advances in peripheral nerve regeneration
Scheib, J. L., & Höke, A. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.227 · Cited by 769
The role of microglia and macrophages in the pathophysiology of the CNS
Stollg, G., & Jander, S. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00083-5 · Cited by 683
Nerve Injury, Axonal Degeneration and Neural Regeneration: Basic Insights
Stoll, G., & Müller, H. W. (1999) · Brain Pathology · doi:10.1111/j.1750-3639.1999.tb00229.x · Cited by 601
“There have been longstanding controversies to what extent Schwann cells versus macrophages and to what extent resident endoneurial (42) versus hematogenous macrophages are involved in myelin clearance (reviewed in 13).”
BackgroundRole of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury
Chen, P., Piao, X., & Bonaldo, P. (2015) · Acta Neuropathologica · doi:10.1007/s00401-015-1482-4 · Cited by 546
Tumour necrosis factor-α induces ectopic activity in nociceptive primary afferent fibres
Sorkin, L. S., Xiao, W.-H., Wagner, R., & Myers, R. R. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00147-4 · Cited by 503
Pathophysiology of Peripheral Neuropathic Pain: Immune Cells and Molecules
Thacker, M. A., Clark, A. K., Marchand, F., & McMahon, S. B. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000275190.42912.37 · Cited by 380
Macrophage biology in the peripheral nervous system after injury
Zigmond, R. E., & Echevarría, F. D. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.12.001 · Cited by 383
“In most tissues, including in the nervous system, two classes of macrophages are distinguishable: resident macrophages and infiltrating macrophages (Griffin et al., 1993).”
Bartholdi, D., & Schwab, M. E. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01497.x · Cited by 357
Effect of modulating macrophage phenotype on peripheral nerve repair
Mokarram, N., Merchant, A., Mukhatyar, V., Patel, G., & Bellamkonda, R. V. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.08.050 · Cited by 334
“Macrophages, which are mainly recruited from circulation, account for the bulk of phagocytosis within days of peripheral nerve injury and play a critical role in debris removal, growth factor production, and remodeling of the extracellular matrix (ECM) of the distal nerve[20, 21].”
BackgroundThe role of macrophages in immune-mediated damage to the peripheral nervous system
Kiefer, R., Kieseier, B. C., Stoll, G., & Hartung, H. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00060-5 · Cited by 301
Immunopathogenesis and treatment of the guillain‐barré syndrome—part I
Hartung, H., Toyka, K. V., Pollard, J. D., et al. (1995) · Muscle & Nerve · doi:10.1002/mus.880180202 · Cited by 289
The Role of Macrophages in Wallerian Degeneration
Brück, W. (1997) · Brain Pathology · doi:10.1111/j.1750-3639.1997.tb01060.x · Cited by 280
Mueller, M., Reif-Leonhard, C., Wacker, K., Ringelstein, E. B., Okabe, M., Hickey, W. F., & Kiefer, R. (2003) · Laboratory Investigation · doi:10.1097/01.lab.0000056993.28149.bf · Cited by 256
“M acrophages play a central role in the pathogen-esis of peripheral nerve diseases and during regeneration from traumatic nerve lesions (Bruck, 1997; Griffin et al, 1993; Kiefer et al, 2001).”
Dubový, P. (2011) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2011.02.011 · Cited by 229
Inflammation and hyperalgesia induced by nerve injury in the rat: a key role of mast cells
Zuo, Y., Perkins, N. M., Tracey, D. J., & Geczy, C. L. (2003) · Pain · doi:10.1016/s0304-3959(03)00261-6 · Cited by 221
“Macrophages play an important role in neural inflammation and degeneration after axotomy (Griffin et al., 1993; Brück, 1997) and are also critical for recovery and regeneration after nerve injury (Kiefer et al.”
BackgroundSafety of long-term electrical peripheral nerve stimulation: review of the state of the art
Günter, C., Delbeke, J., & Ortiz-Catalan, M. (2019) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-018-0474-8 · Cited by 198
Kieseier, B. C., Kiefer, R., Gold, R., Hemmer, B., Willison, H. J., & Hartung, H. (2004) · Muscle & Nerve · doi:10.1002/mus.20076 · Cited by 212
Rapid Response of Identified Resident Endoneurial Macrophages to Nerve Injury
Mueller, M., Wacker, K., Ringelstein, E. B., Hickey, W. F., Imai, Y., & Kiefer, R. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63070-2 · Cited by 208
“Endoneurial macrophages are not a homogenous cell population.(6) In addition to hematogenous macrophages entering the nerve in large numbers during disease, a population of resident endoneurial macrophages exists in the normal peripheral nerve that accounts for up to 9% of the entire endoneurial cell population.”
BackgroundMyelin phagocytosis by macrophages and nonmacrophages during Wallerian degeneration
Hirata, K., & Kawabuchi, M. (2002) · Microscopy Research and Technique · doi:10.1002/jemt.10108 · Cited by 202
“…up about 2–4% of the total cell population in rodents (Oldfors, 1980; Schubert and Friede, 1981) and that they may constitute a local immune system for the PNS with functions similar to those of microglial cells in the central nervous system (reviewed in Griffin et al., 1993; Monaco et al., 1992).”
InfluentialGlial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor
Wu, H., Bellmunt, E., Scheib, J. L., Venegas, V., Burkert-Kautzsch, C., Reichardt, L. F., Zhou, Z., Fariñas, I., & Carter, B. D. (2009) · Nature Neuroscience · doi:10.1038/nn.2446 · Cited by 195
FK506 and the role of immunophilins in nerve regeneration
Gold, B. G. (1997) · Molecular Neurobiology · doi:10.1007/bf02740664 · Cited by 191
Morphometric and ultrastructural changes with ageing in mouse peripheral nerve
Ceballos, D., Cuadras, J., Verdú, E., & Navarro, X. (1999) · Journal of Anatomy · doi:10.1046/j.1469-7580.1999.19540563.x · Cited by 180
“Macrophages play an important role in nerve degeneration and repair by means of secretion of interleukins, promoting the expression of nerve growth factors by denervated SC and activating regenerative processes (Griffin et al. 1993; Rothwell & Strijbos, 1995).”
Backgroundβ4 integrin and other Schwann cell markers in axonal neuropathy
Quattrini, A., Previtali, S. C., Feltri, M. L., Canal, N., Nemni, R., & Wrabetz, L. G. (1996) · Glia · doi:10.1002/(sici)1098-1136(199608)17:4 · Cited by 80
The neuroimmunology of degeneration and regeneration in the peripheral nervous system
Oranburg, T. D., Lindborg, J. A., Niemi, J. P., & Zigmond, R. E. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.09.027 · Cited by 180
“Resident macrophages comprise 2–9% of all cells in peripheral nerves, express CR3, and are known to be phagocytic (for review see Griffin et al., 1993).”
Chen, P., Cescon, M., Zuccolotto, G., Nobbio, L., Colombelli, C., Filaferro, M., Vitale, G., Feltri, M. L., & Bonaldo, P. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1369-9 · Cited by 173
“Following PNS injury, macrophages not only contribute to debris clearance, growth factor production and ECM remodeling in the distal nerve, but also stimulate regeneration near the axotomized neuronal cell bodies [20, 32, 34].”
BackgroundInfluentialKieseier, B. C., Tani, M., Mahad, D., Oka, N., Ho, T. W., Woodroofe, M. N., Griffin, J. W., Toyka, K. V., Ransohoff, R. M., & Hartung, H. (2002) · Brain · doi:10.1093/brain/awf070 · Cited by 151
Self-citationShimeld, C. (1995) · Journal of Neuroimmunology · doi:10.1016/0165-5728(95)00068-d · Cited by 148
Fenrich, K. K., & Gordon, T. (2004) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100053798 · Cited by 142
Dailey, A. T., Avellino, A. M., Benthem, L., Silver, J., & Kliot, M. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-17-06713.1998 · Cited by 140
“One of the most striking cellular responses during Wallerian degeneration (WD) in the PNS is the proliferation and infiltration of macrophages (Griffin et al., 1993; Perry, 1994; Bruck, 1997).”
Fernández‐Valle, C., Bunge, R. P., & Bunge, M. B. (1995) · Journal of Neurocytology · doi:10.1007/bf01179817 · Cited by 134
Anterograde Transport of Tumor Necrosis Factor-α in the Intact and Injured Rat Sciatic Nerve
Schäfers, M., Geis, C., Brors, D., et al. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-02-00536.2002 · Cited by 119
“Early after nerve injury, TNF protein and mRNA at the injury site are upregulated endoneurially primarily in nonneuronal cells (Griffin et al., 1993; Bizette et al., 1996; La Fleur et al., 1996; Wagner and Myers, 1996a; Sommer and Schäfers, 1998; Taskinen et al., 2000), and after a brief temporal…”
BackgroundNeuronal death after peripheral nerve injury and experimental strategies for neuroprotection
Hart, A. M., Terenghi, G., & Wiberg, M. (2008) · Neurological Research · doi:10.1179/174313208x362479 · Cited by 106
Microscopic Anatomy of the Peripheral Nervous System
Berthold, C. ‐., Fraher, J., King, R. H. M., & Rydmark, M. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7216-9491-7.50006-5 · Cited by 111
Levy, D., Kubes, P., & Zochodne, D. W. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.5.411 · Cited by 104
“Secretions of pro-inflammatory cytokines IL-1b and TNF-a, and apolipoprotein-E by macrophages (1) may further regulate the degeneration and regeneration processes.”
BackgroundThe macrophage: a key player in the pathophysiology of peripheral neuropathies
Msheik, Z., Massry, M. E., Rovini, A. M. F., Billet, F., & Desmoulière, A. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02454-6 · Cited by 108
“Studies also show that macrophages exist in the endoneurium, between myelin sheaths and in close contact with axons [56, 59, 62].”
BackgroundThe dynamics of macrophage recruitment after nerve transection
Taskinen, H., & Röyttä, M. (1997) · Acta Neuropathologica · doi:10.1007/s004010050611 · Cited by 100
“In the normal intact peripheral nerve there are resident macrophages which comprise 2‐9% of all endoneurial cells [ 11 ].”
BackgroundSheth, S., Li, X., Binder, S. W., et al. (2011) · Modern Pathology · doi:10.1038/modpathol.2010.203 · Cited by 97
Kieseier, B. C., Clements, J. M., Pischel, H., Wells, G., Miller, K., Gearing, A. J. H., & Hartung, H. ‐. (1998) · Annals of Neurology · doi:10.1002/ana.410430404 · Cited by 95
Peripheral Nerve Regeneration by Secretomes of Stem Cells from Human Exfoliated Deciduous Teeth
Sugimura, Y., Katagiri, W., Osugi, M., Kawai, T., Ogata, K., Sakaguchi, K., & Hibi, H. (2015) · Stem Cells and Development · doi:10.1089/scd.2015.0104 · Cited by 96
“In PNI, macrophages, which are mainly recruited from circulation, disrupt and phagocytose axons, produce growth factors, and promote the migration of Schwann cells (SCs) [1,13].”
Increased expression of chemokines (MCP‐1, MIP‐1α, RANTES) after peripheral nerve transection
Taskinen, H., & Röyttä, M. (2000) · Journal of the Peripheral Nervous System · doi:10.1046/j.1529-8027.2000.00009.x · Cited by 94
The immunocompetence of Schwann cells
zu Hörste, G. M., Hu, W. W., Hartung, H., et al. (2007) · Muscle & Nerve · doi:10.1002/mus.20893 · Cited by 92
Myelin and macrophages in the PNS: An intimate relationship in trauma and disease
Klein, D., & Martini, R. (2015) · Brain Research · doi:10.1016/j.brainres.2015.11.033 · Cited by 89
Kleinschnitz, C., Brinkhoff, J., Zelenka, M., Sommer, C., & Stoll, G. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2003.12.013 · Cited by 90
“The early increase in IL-1h and TNF-a levels after CCI very well correspond to previous histological studies showing upregulation of these cytokines at the protein level and their cellular expression by Schwann cells and macrophages (Griffin et al., 1993; Wagner and Myers, 1996; La Fleur et al., 1996; Sommer et al., 1…”
BackgroundOrigin and Differentiation of Nerve-Associated Macrophages
Kolter, J., Kierdorf, K., & Henneke, P. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1901077 · Cited by 91
IgG receptor IIa alleles determine susceptibility and severity of Guillain-Barré syndrome
van der Pol, W. L., van den Berg, L. H., Scheepers, R. H. M., van der Bom, J. G., van Doorn, P. A., van Koningsveld, R., van den Broek, M. C. L., Wokke, J. H. J., & van de Winkel, J. G. J. (2000) · Neurology · doi:10.1212/wnl.54.8.1661 · Cited by 86
Karanth, S., YANG, G., YEH, J., et al. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2006.05.024 · Cited by 81
The Role of Cytokines in Schwann Cell Damage, Protection, and Repair
Lisak, R. P., Skundric, D. S., Bealmear, B., et al. (1997) · The Journal of Infectious Diseases · doi:10.1086/513788 · Cited by 73
Effect of aluminium on expression and processing of amyloid precursor protein
Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., RIMA, B. K., Morris, C. M., Candy, J. M., & Edwardson, J. A. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19961115)46:4 · Cited by 24
Créange, A., Bélec, L., Clair, B., et al. (1996) · Journal of Neuroimmunology · doi:10.1016/0165-5728(96)00075-6 · Cited by 69
“Demyelination could be mediated by activated lymphocytes (Iqbal et al., 1981) and by resident and recruited macrophages (Griffin et al., 1993).”
Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice
Yuan, X., Klein, D., Kerscher, S. R., West, B. L., Weis, J., Katona, I., & Martini, R. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.3030-17.2018 · Cited by 69
“lesioned nerves during Wallerian degeneration, eventually facilitating axonal regrowth after phagocytosis of myelin (Griffin et al., 1993; Stoll and Müller, 1999; Martini et al., 2008, 2013; Scheib and Höke, 2013; Klein and Martini, 2016; Martini and Willison, 2016).”
BackgroundTNF α: A Trigger of Autonomic Dysfunction
Hermann, G. E., & Rogers, R. C. (2007) · The Neuroscientist · doi:10.1177/1073858407305725 · Cited by 64
Central nervous system pathology in patients with the Guillain-Barre syndrome
Maier, H. (1997) · Brain · doi:10.1093/brain/120.3.451 · Cited by 64
Role of HIV in the pathogenesis of distal symmetrical peripheral neuropathy
Rizzuto, N., Cavallaro, T., Monaco, S., et al. (1995) · Acta Neuropathologica · doi:10.1007/bf00296507 · Cited by 62
“various physiological and pathological functions [3, 17 , 30].”
BackgroundBourde, O., Kiefer, R., Toyka, K. V., et al. (1996) · Journal of Neuroimmunology · doi:10.1016/0165-5728(96)00087-2 · Cited by 62
Schreiber, R. C., Krivacic, K. A., Kirby, B., Vaccariello, S. A., Wei, T., Ransohoff, R. M., & Zigmond, R. E. (2001) · Neuroreport · doi:10.1097/00001756-200103050-00034 · Cited by 61
Rajaram, A., Chen, D., & Schreyer, D. J. (2012) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2012.0006 · Cited by 63
“86 Beside the addition of supportive cells, their orientation in scaffolds is also necessary for the maintenance of adequate function.”
Endoneurial Fibroblast-Like Cells
Richard, L., Topilko, P., Magy, L., Decouvelaere, A., Charnay, P., Funalot, B., & Vallat, J. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318270a941 · Cited by 59
“In 1993, Griffin et al (4) indicated that normal nerve macrophages were rarely distinguished from endoneurial fibroblasts before the availability of specific immunomarkers.”
BackgroundCréange, A., Bélec, L., Clair, B., et al. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.64.2.162 · Cited by 58
Levi, A. D. (1996) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(96)00055-6 · Cited by 58
Immune circuitry in the peripheral nervous system
Kieseier, B. C., Hartung, H., & Wiendl, H. (2006) · Current Opinion in Neurology · doi:10.1097/01.wco.0000245365.51823.72 · Cited by 57
Jander, S., Lausberg, F., & Stoll, G. (2001) · Brain Pathology · doi:10.1111/j.1750-3639.2001.tb00378.x · Cited by 55
“Previous studies suggested the ED2 antigen as a marker for resident PNS macrophages (17, 33).”
BackgroundBuckenmeyer, M. J., Meder, T. J., Prest, T. A., & Brown, B. N. (2019) · Methods · doi:10.1016/j.ymeth.2019.07.023 · Cited by 56
The diagnostic value of sural nerve T cells in chronic inflammatory demyelinating polyneuropathy
Bosboom, W. M. J., van den Berg, L. H., de Boer, L., et al. (1999) · Neurology · doi:10.1212/wnl.53.4.837 · Cited by 54
Axonal degeneration and disorders of the axonal cytoskeleton
Griffin, J. W., George, E. B., Hsieh, S., & Glass, J. D. (1995) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195082937.003.0020 · Cited by 55
Self-citationAndorfer, B., Kieseier, B. C., Mathey, E. K., Armati, P. J., Pollard, J. D., Oka, N., & Hartung, H.-P. (2001) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(01)00306-x · Cited by 53
“…act as antigen presenters and are of critical importance in the amplification and effector phase of immune-mediated demyelination by the secretion of proinflammatory cytokines, the release of active mediators, and enhanced Žphagocytosis Hughes, 1990; Griffin et al., 1993; Hartung .et al., 1995 .”
BackgroundThe Role of the Mouse Macrophage Scavenger Receptor in Myelin Phagocytosis
Costa, C. C., van der Laan, L. J. W., Dijkstra, C. D., & Brück, W. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01694.x · Cited by 53
Motor neuron–immune interactions: the vicious circle of ALS
Barbeito, A. G., Mesci, P., & Boillée, S. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0429-0 · Cited by 57
“Macrophages at the periphery include the ones in the nerves, and activated macrophages are present in the peripheral nerves upon axonal degeneration in neurodegenerative conditions (Griffin et al. 1993) including in the sciatic nerves of ALS mice or rats (Graber et al. 2010; Chiu et al. 2009).”
Axonal viability and the persistence of thermal hyperalgesia after partial freeze lesions of nerve
Myers, R. R., Heckman, H. M., & Powell, H. C. (1996) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(96)00038-x · Cited by 51
Bumsted (1999) · doi:10.1002/(sici)1096-9861(19990125)403:4
Recovery and prognosticators of paralysis in West Nile virus infection
Cao, N. J., Ranganathan, C., Kupsky, W. J., et al. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2005.05.007 · Cited by 50
“2C, arrowheads and arrows), indicating that the cells were recruited into the roots in association with Wallerian degeneration [21,22].”
BackgroundAutoimmune responses in peripheral nerve
Hartung, H., Willison, H. J., Jung, S., Pette, M., Toyka, K. V., & Giegerich, G. (1996) · Springer Seminars in Immunopathology · doi:10.1007/bf00792612 · Cited by 49
“These cells usually lie outside the basal lamina of the blood vessels and have a dendritic appearance [48, 126].”
BackgroundComplement depletion affects demyelination and inflammation in experimental allergic neuritis
Vriesendorp, F. J., Flynn, R. E., Pappolla, M. A., et al. (1995) · Journal of Neuroimmunology · doi:10.1016/0165-5728(95)00006-n · Cited by 50
Liu, J., Wu, M., He, J., Xiao, C., Xue, Y., Fu, T., Lin, C., Dong, D., & Li, Z. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.08.009 · Cited by 50
Gold, B. G., Voda, J., Yu, X., & Gordon, H. S. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.01.005 · Cited by 49
Venezie, R. D., Toews, A. D., & Morell, P. (1995) · Journal of Neuroscience Research · doi:10.1002/jnr.490400111 · Cited by 48
“also complicated by the fact that macrophages are forced into available spaces between nerve fibers, thus distorting their shape (Griffin et al., 1993).”
BackgroundAutoimmune diseases of the peripheral nervous system
Kieseier, B. C., Lehmann, H. C., & zu Hörste, G. M. (2011) · Autoimmunity Reviews · doi:10.1016/j.autrev.2011.05.011 · Cited by 47
Li, M., Peake, P. W., CHARLESWORTH, J. A., Tracey, D. J., & Moalem‐Taylor, G. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05971.x · Cited by 46
“ED1 predominantly labels recruited macrophages, whereas ED2 labels tissue macrophages; intact peripheral nerves contain a resident population of ED2 macrophages that comprise from 2 to 9% of the cells (Oldfors, 1980; Monaco et al., 1992; Griffin et al., 1993).”
BackgroundFansa, H., Schneider, W., Wolf, G. L., et al. (2002) · Muscle & Nerve · doi:10.1002/mus.10165 · Cited by 46
“ently a major effect of IGF-I, its administration cannot improve regeneration by this means.(3,24) Moreover, the engineered grafts used in this study”
Schreiber, R. C., Shadiack, A. M., Bennett, T. A., et al. (1995) · Journal of Neurobiology · doi:10.1002/neu.480270203 · Cited by 46
Bosboom, W. M. J., van den Berg, L. H., Mollee, I., et al. (2001) · Neurology · doi:10.1212/wnl.56.1.74 · Cited by 46
Jang, S. Y., Yoon, B.-A., Shin, Y. K., Yun, S. H., Jo, Y. R., Choi, Y. Y., Ahn, M., Shin, T., Park, J. I., Kim, J. K., et al. (2017) · Glia · doi:10.1002/glia.23200 · Cited by 46
HIV‐associated neuropathies: role of HIV‐1, CMV, and other viruses
Kolson, D. L., & González‐Scarano, F. (2001) · Journal of the Peripheral Nervous System · doi:10.1046/j.1529-8027.2001.006001002.x · Cited by 45
“Ho et al. (1985) first isolated HIV by culture from the sural nerve of a patient with an HIV-associated IDP. de la Monte et al. (1988) examined nerve biopsies from 11 patients with either DSP or CIDP, and compared them with those from 10 asymptomatic patients. HIV was cultivated from 3 ⁄5 neuropathy patients, although…”
BackgroundResultInfluentialZettl, U. K., Gold, R., Toyka, K. V., & Hartung, H. (1996) · Acta Neuropathologica · doi:10.1007/s004010050437 · Cited by 45
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
Tabrizi, S. J., Workman, J. M., Hart, P. E., Mangiarini, L., Mahal, A., Bates, G. P., Cooper, J. A. D., & Schapira, A. H. V. (2000) · Annals of Neurology · doi:10.1002/1531-8249(200001)47:1 · Cited by 353
Wallerian degeneration in ICAM-1-deficient mice.
Vougioukas, V. I., Roeske, S., Michel, U., et al. (1998) · PubMed · Cited by 45
Yang, R., Strong, J. A., & Zhang, J. (2009) · Molecular Pain · doi:10.1186/1744-8069-5-26 · Cited by 44
“Many cytokines and chemokines with previously established roles in the immune system have also been found to have direct effects on peripheral and central neurons, and to play key roles in pathologic pain [1-3].”
BackgroundThe Astroglial Response to Wallerian Degeneration after Spinal Cord Injury in Humans
Puckett, W., Hiester, E. D., Norenberg, M. D., et al. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6692 · Cited by 43
Review: Myelin clearance is critical for regeneration after peripheral nerve injury
Yuan, Y., Wang, Y., Wu, S., & Zhao, M. Y. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.908148 · Cited by 49
Immunoglobulin IgG Fc-receptor polymorphisms and HLA class II molecules in Guillain-Barré syndrome
Sinha, S., Prasad, K. N., Jain, D. K., et al. (2010) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2009.01229.x · Cited by 42
Rauschka, H., Jellinger, K. A., Lassmann, H., et al. (2003) · European Journal of Neurology · doi:10.1046/j.1468-1331.2003.00644.x · Cited by 41
“Our data on the proportions of macrophages, lymphocytes and T-cell subtypes are in agreement with the findings in the GBS control cases (data shown in Maier et al., 1997) and with previous studies on GBS (Honavar et al., 1991; Griffin et al., 1993, 1995; HaferMacko et al., 1996).”
ResultOsteopontin: A novel axon‐regulated Schwann cell gene
Jander, S., Bussini, S., Neuen‐Jacob, E., et al. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10099 · Cited by 41
“…peripheral nervous system (PNS) is characterized by rapid disintegration of the distal axon cylinder and highly coordinated responses of myelin-forming Schwann cells and infiltrating blood-derived macrophages (Griffin et al., 1993; Brück, 1997; Stoll and Müller, 1999; Mirsky and Jessen, 1999).”
BackgroundWang, L., Hu, B., Wong, W. M., Lu, P., Wu, W., & Xu, X. (2009) · Neuropathology · doi:10.1111/j.1440-1789.2008.00969.x · Cited by 41
Créange, A., Gregson, N. A., & Hughes, R. A. (2003) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(02)00430-7 · Cited by 39
“Cellular immune responses and release of neurotoxic molecules may also be involved (Griffin et al., 1993; Hartung, 1995).”
BackgroundAmr, S. M., El‐Mofty, A. O., Amin, S., Morsy, A. M., El-Malt, O. M., & Abdel-Aal, H. A. (2000) · Microsurgery · doi:10.1002/1098-2752(2000)20:5 · Cited by 46
Different muscle graft denaturing methods and their use for nerve repair
Whitworth, I. H., Doré, C. J., Hall, S. M., et al. (1995) · British Journal of Plastic Surgery · doi:10.1016/0007-1226(95)90126-4 · Cited by 38
Press, R., Nennesmo, I., Kouwenhoven, M. C. M., Huang, Y.-M., Link, H., & Pashenkov, M. V. (2005) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.09.020 · Cited by 38
“These spindle-shaped cells corresponded morphologically to tissue-resident macrophages that have been described previously (Griffin et al., 1993; Kiefer et al., 2001).”
BackgroundHyperalgesic actions of cytokines on peripheral nerves
Myers, R. R., Wagner, R., & Sorkin, L. S. (1999) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8749-6_6 · Cited by 38
“the injury site [11] and resulting lowered oxygen levels [69], cytOtoxiCity of endoneuria I components such as Schwann cells and some axons [43,52], the upreg ulation of nerve growth factor production [70] with associated hyperalgesia actions [71], and the upregulation of intracellular adhesion molecules and macropha…”
BackgroundMüller, M., Reif-Leonhard, C., Krauthausen, M., Wacker, K., & Kiefer, R. (2010) · Journal of the Peripheral Nervous System · doi:10.1111/j.1529-8027.2010.00295.x · Cited by 37
“…spare a long-term resident macrophage population, which would, to a certain extent, resemble the situation of the CNS, where perivascular macrophages are exchanged (Hickey and Kimura, 1988; Bechmann et al., 2001a) and microglial cells are likely to be long-term resident (Ransohoff and Perry, 2009).”
Background
Metadata
- Authors
- GRIFFIN, J. W., GEORGE, R., & HO, T.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- GRIFFIN, JOHN W.
- ORCID
- HO, TONY
- Venue
- Journal of Neuropathology and Experimental Neurology
- Publisher
- Oxford University Press (OUP)
- Published
- 1993-11
- Volume
- 52
- Issue
- 6
- Pages
- 553-560
- ISSN
- 0022-3069 (ISSN-L)
- OpenAlex
- W2000601562
- Cited by
- 222
- References
- 0
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 5 · 2017: 6 · 2016: 3 · 2015: 5 · 2014: 10 · 2013: 7 · 2012: 7
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuropathology & Experimental Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- macrophages, peripheral nerves, peripheral nerve inflammation, nerve injury, glial cells, neuroinflammation
- MeSH terms
- Animals, Axons, Cell Differentiation, Cell Division, Demyelinating Diseases, Interferons, Interleukins, Macrophages, Peripheral Nervous System Diseases, Peripheral Nerves, Proto-Oncogene Proteins, Recruitment, Neurophysiological, Tumor Necrosis Factor-alpha, Wallerian Degeneration, Receptors, Colony-Stimulating Factor, Proto-Oncogene Proteins c-kit, Receptor Protein-Tyrosine Kinases, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review