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Cited by 168Muscle metabolism and nutritionSports Performance and TrainingBiochemical effects in animals

The DOI matches its Crossref record; 28 of the 29 references it cites were found in a registry or an index.

Effects of oral creatine supplementation on muscular strength and body composition

BECQUE, M. DANIEL, LOCHMANN, JOHN D., MELROSE, DONALD R.·2000·Medicine & Science in Sports & Exercise
DOI 10.1097/00005768-200003000-00016
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Abstract

PURPOSE: The purpose of this investigation was to examine the effects of 6 wk of oral creatine supplementation during a periodized program of arm flexor strength training on arm flexor IRM, upper arm muscle area, and body composition. METHODS: Twenty-three male volunteers with at least 1 yr of weight training experience were assigned in a double blind fashion to two groups (Cr, N = 10; Placebo, N = 13) with no significant mean pretest one repetition maximum (IRM) differences in arm flexor strength. Cr ingested 5 g of creatine monohydrate in a flavored, sucrose drink four times per day for 5 d. After 5 d, supplementation was reduced to 2 g x d(-1). Placebo ingested a flavored, sucrose drink. Both drinks were 500 mL and made with 32 g of sucrose. IRM strength of the arm flexors, body composition, and anthropometric upper arm muscle area (UAMA) were measured before and after a 6-wk resistance training program. Subjects trained twice per week with training loads that began at 6RM and progressed to 2RM. RESULTS: IRM for Cr increased (P < 0.01) from (mean +/- SD) 42.8 +/- 17.7 kg to 54.7 +/- 14.1 kg, while IRM for Placebo increased (P < 0.01) from 42.5 +/- 15.9 kg to 49.3 +/- 15.7 kg. At post-test IRM was significantly (P < 0.01) greater for Cr than for Placebo. Body mass for Cr increased (P < 0.01) from 86.7 +/- 14.7 kg to 88.7 +/- 13.8 kg. Fat-free mass for Cr increased (P < 0.01) from 71.2 +/- 10.0 kg to 72.8 +/- 10.1 kg. No changes in body mass or fat-free mass were found for Placebo. There were no changes in fat mass and percent body fat for either group. UAMA increased (P < 0.01) 7.9 cm2 for Cr and did not change for Placebo. CONCLUSION: Creatine supplementation during arm flexor strength training lead to greater increases in arm flexor muscular strength, upper arm muscle area, and fat-free mass than strength training alone.

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Crossref · 10.1097/00005768-200003000-00016

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Citations

Cites

Show all 29 references

Research works printed but not linked: 12

  1. Brozek, 1963, Ann N Y Acad Sci, 110, 113???140,
  2. Casey, 1996, Am J Physiol, 271, E31
  3. Earnest, 1997, J Strength Cond Res, 11, 234???238,
  4. Greenhaff, 1994, Am J Physiol, 226, E725
  5. Greenhaff, 1994, J Physiol Lond, 476, 84P,
  6. Harris, 1993, J Physiol Lond, 476, 74,
  7. Heymsfield, 1982, Am J Clin Nutr, 36, 680???690,
  8. Kreider, 1995, Strength Cond, 17, 72???73,
  9. Kreider, 1998, Med Sci Sports Exerc, 30, 73???82,
  10. Mujika, 1996, Med Sci Sports Exerc, 28, 1435???1441,
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  12. Wilmore, 1969, Med Sci Sport, 1, 87???90,

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Metadata

Authors
BECQUE, M. D., LOCHMANN, J. D., & MELROSE, D. R.
Affiliations
Southern Illinois University Carbondale (US)
Venue
Medicine & Science in Sports & Exercise
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2000-03
Volume
32
Issue
3
Pages
654-658
ISSN
0195-9131 (ISSN-L)
DOI
10.1097/00005768-200003000-00016
OpenAlex
W2132056205
Cited by
168
References
29
Citations by year
2026: 2 · 2025: 5 · 2024: 8 · 2023: 6 · 2022: 4 · 2021: 4 · 2020: 3 · 2019: 7 · 2018: 4 · 2017: 8 · 2016: 6 · 2015: 7 · 2014: 12 · 2013: 6 · 2012: 3
FWCI
3.76
Type
journal article
Language
en
Open access
closed
Locations
  • Medicine & Science in Sports & Exercise (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Physiology (medical) › Biochemical effects in animals
Keywords
creatine monohydrate, muscle strength, upper arm muscle area, body composition, fat-free mass, resistance training, training periodization, one-repetition maximum, weight gain, fat mass, body fat percentage, training load progression, exercise frequency, exercise intensity, training duration
MeSH terms
Adult, Body Composition, Creatine, Double-Blind Method, Humans, Male, Task Performance and Analysis, Weight Lifting, Weight-Bearing, Treatment Outcome, Dietary Supplements

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