The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Is infection risk linked to exercise workload?
Abstract
Anecdotal, survey, and epidemiological data suggest that endurance athletes are at an increased risk for upper respiratory tract infection (URTI) during periods of heavy training and the 1 - to 2-wk period after race events. The majority of athletes, however, who participate in endurance race events do not experience illness. Of greater public health importance is the consistent finding of a reduction in URTI risk reported by fitness enthusiasts and athletes who engage in regular exercise training while avoiding overreaching/overtraining. Although it naturally follows that infection risk should in some way be linked to acute and chronic exercise-induced alterations in immunity, attempts thus far to measure this association have been unsuccessful. There is growing evidence that for several hours subsequent to heavy exertion, several components of both the innate and adaptive immune system exhibit suppressed function. The immune response to heavy exertion is transient, however, and further research on the mechanisms underlying the immune response to prolonged and intensive endurance exercise is necessary before meaningful clinical applications can be drawn. Some attempts have been made through chemical or nutritional means (e.g., indomethacin, glutamine, vitamin C, and carbohydrate supplementation) to attenuate immune changes after intensive exercise to lower the risk of infection. No consistent relationship between nutritional interventions, exercise immunology, and alteration in URTI risk has yet been established.
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Cites
Pro‐ and anti‐inflammatory cytokine balance in strenuous exercise in humans
Ostrowski, K., Rohde, T., Asp, S., Schjerling, P., & Pedersen, B. K. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.287ad.x · Cited by 1,014
Physical activity and immune function in elderly women
NIEMAN, D. C., HENSON, D. A., GUSEWITCH, G., WARREN, B. J., DOTSON, R. C., BUTTERWORTH, D. E., & NEHLSEN-CANNARELLA, S. L. (1993) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199307000-00011 · Cited by 393
Self-citationCarbohydrate and the cytokine response to 2.5 h of running
Nehlsen-Cannarella, S. L., Fagoaga, O. R., Nieman, D. C., Henson, D. A., Butterworth, D. E., Schmitt, R. L., Bailey, E. M., Warren, B. J., Utter, A., & Davis, J. M. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.5.1662 · Cited by 311
Peters, E., Goetzsche, J., Grobbelaar, B., & Noakes, T. (1993) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/57.2.170 · Cited by 280
Influence of mode and carbohydrate on the cytokine response to heavy exertion
NIEMAN, D. C., NEHLSEN-CANNARELLA, S. L., FAGOAGA, O. R., HENSON, D. A., UTTER, A., DAVIS, J. M., WILLIAMS, F., & BUTTERWORTH, D. E. (1998) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199805000-00005 · Cited by 233
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The compelling link between physical activity and the body's defense system
Nieman, D. C., & Wentz, L. M. (2019) · Journal of Sport and Health Science · doi:10.1016/j.jshs.2018.09.009 · Cited by 1,340
Self-citationDoyle, C., Kushi, L. H., Byers, T., Courneya, K. S., Demark-Wahnefried, W., Grant, B., McTiernan, A., Rock, C. L., Thompson, C., Gansler, T., et al. (2006) · CA: A Cancer Journal for Clinicians · doi:10.3322/canjclin.56.6.323 · Cited by 950
Exercise, nutrition and immune function
Gleeson, M., Nieman, D. C., & Pedersen, B. K. (2004) · Journal of Sports Sciences · doi:10.1080/0264041031000140590 · Cited by 362
Self-citationModerate to vigorous physical activity and risk of upper-respiratory tract infection
MATTHEWS, C. E., OCKENE, I. S., FREEDSON, P. S., ROSAL, M. C., MERRIAM, P. A., & HEBERT, J. R. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200208000-00003 · Cited by 287
Gleeson, M., Bishop, N., Oliveira, M., McCauley, T., Tauler, P., & Muhamad, A. S. (2012) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.2010.01272.x · Cited by 165
Metadata
- Authors
- NIEMAN, D. C.
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2000-07
- Volume
- 32
- Issue
- Supplement
- Pages
- S406-S411
- ISSN
- 0195-9131 (ISSN-L)
- OpenAlex
- W2020700357
- Cited by
- 258
- References
- 5
- FWCI
- 7.24
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
