The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
A Review of Risk Factors for Catheter-Related Bloodstream Infection Caused by Percutaneously Inserted, Noncuffed Central Venous Catheters: Implications for Preventive Strategies
Abstract
Strategies for preventing central venous catheter (CVC)-related bloodstream infection are most likely to be effective if guided by an understanding of the risk factors associated with these infections. In this critical review of published studies of risk factors for CVC-related bloodstream infection that were prospective and used multivariable techniques of data analysis or that were randomized trials of a preventive measure, a significantly increased risk of catheter-related bloodstream infection was associated with inexperience of the operator and nurse-to-patient ratio in the intensive care unit, catheter insertion with less than maximal sterile barriers, placement of a CVC in the internal jugular or femoral vein rather than subclavian vein, placement in an old site by guidewire exchange, heavy colonization of the insertion site or contamination of a catheter hub, and duration of CVC placement > 7 days. Prospective studies or randomized trials of control measures focusing on these risk factors have been shown to reduce risk significantly: formal training in CVC insertion and care, use of maximal sterile barriers at insertion, use of chlorhexidine rather than povidone-iodine for cutaneous antisepsis, applying a topical anti-infective cream or ointment or a chlorhexidine-impregnated dressing to the insertion site, and the use of novel catheters with an anti-infective surface or a contamination resistant hub. Better prospective studies of sufficient size to address all potential risk factors, including insertion site and hub colonization, insertion technique, and details of follow-up care, would enhance our understanding of the pathogenesis of CVC-related bloodstream infection and guide efforts to develop more effective strategies for prevention.
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Cites
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Prevention of Intravascular Catheter-Related Infections
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Self-citationA Comparison of Two Antimicrobial-Impregnated Central Venous Catheters
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Cited by
Guidelines for the prevention of intravascular catheter-related infections
O'Grady, N. P., Alexander, M., Burns, L. A., Dellinger, E. P., Garland, J., Heard, S. O., Lipsett, P. A., Masur, H., Mermel, L. A., Pearson, M. L., et al. (2011) · American Journal of Infection Control · doi:10.1016/j.ajic.2011.01.003 · Cited by 1,066
Guidelines for the Prevention of Intravascular Catheter–Related Infections
O'Grady, N. P., Alexander, M., Dellinger, E. P., Gerberding, J. L., Heard, S. O., Maki, D. G., Masur, H., McCormick, R. D., Mermel, L. A., Pearson, M. L., et al. (2002) · Infection Control & Hospital Epidemiology · doi:10.1017/s0195941700080577 · Cited by 319
Self-citationGarnacho-Montero, J., Aldabó-Pallás, T., Palomar-Martínez, M., Vallés, J., Almirante, B., Garcés, R., Grill, F., Pujol, M., Arenas-Giménez, C., Mesalles, E., et al. (2008) · Intensive Care Medicine · doi:10.1007/s00134-008-1204-7 · Cited by 150
A mouse model to evaluate the interface between skin and a percutaneous device
Isenhath, S. N., Fukano, Y., Usui, M. L., Underwood, R. A., Irvin, C. A., Marshall, A. J., Hauch, K. D., Ratner, B. D., Fleckman, P., & Olerud, J. E. (2007) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31391 · Cited by 59
Underwood, R. A., Usui, M. L., Zhao, G., Hauch, K. D., Takeno, M. M., Ratner, B. D., Marshall, A. J., Shi, X., Olerud, J. E., & Fleckman, P. (2011) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.33125 · Cited by 52
Metadata
- Authors
- SAFDAR, N., KLUGER, D. M., & MAKI, D. G.
- Venue
- Medicine
- Published
- 2002-11
- Volume
- 81
- Issue
- 6
- Pages
- 466-479
- ISSN
- 0025-7974 (ISSN-L)
- OpenAlex
- W2020990310
- Cited by
- 261
- References
- 109
- FWCI
- 12.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- SAFDAR, N., KLUGER, D. M., & MAKI, D. G. (2002). A Review of Risk Factors for Catheter-Related Bloodstream Infection Caused by Percutaneously Inserted, Noncuffed Central Venous Catheters: Implications for Preventive Strategies. Medicine. https://doi.org/10.1097/00005792-200211000-00007
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