The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Orthostatic Intolerance: A Disorder of Young Women
Abstract
Orthostatic intolerance (OI) is a cause of significant disability in otherwise healthy women seen by gynecologists. Orthostatic tachycardia is often the most obvious hemodynamic abnormality found in OI patients, but symptoms may include dizziness, visual changes, discomfort in the head or neck, poor concentration, fatigue, palpitations, tremulousness, anxiety, and, in some cases, fainting (syncope). It is the most common disorder of blood pressure regulation after essential hypertension, and patients with OI are traditionally women of childbearing age. Estimates suggest that at least 500,000 Americans suffer from some form of OI, and such patients comprise the largest group referred to centers specialized in autonomic disorders. This article reviews recent advances made in the understanding of this condition, potential pathophysiological mechanisms contributing to orthostatic intolerance, and therapeutic alternatives currently available for the management of these patients. Target Audience: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this article, the reader will be able to describe the common signs and symptoms associated with idiopathic orthostatic intolerance, to identify the various conditions that have similar presentations as idiopathic orthostatic intolerance and to describe potential treatment options.
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Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome
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“Postural tachycardia syndrome (POTS) is a disorder of chronic orthostatic intolerance that disproportionately affects women of childbearing age [1].”
Background
Metadata
- Authors
- Ali, Y. S., Daamen, N., Jacob, G., Jordan, J., Shannon, J. R., Biaggioni, I., & Robertson, D.
- Affiliations
- Vanderbilt University (US)
- Humboldt-Universität zu Berlin (DE)
- Corresponding author
- Ali, Yasmine S.
- Venue
- Obstetrical & Gynecological Survey
- Published
- 2000-04
- Volume
- 55
- Issue
- 4
- Pages
- 251-259
- ISSN
- 0029-7828 (ISSN-L)
- OpenAlex
- W2041033850
- Cited by
- 64
- References
- 40
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 7 · 2020: 4 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 7 · 2014: 5 · 2013: 1 · 2012: 1
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obstetrical & Gynecological Survey (publishedVersion)
- PubMed (publishedVersion)
- MDC Repository (Max-Delbrueck-Center for Molecular Medicine) (submittedVersion)
- Funders
- National Institutes of Health (5u01ns033460-03)
- National Heart, Lung, and Blood Institute (P01HL056693, P01 HL-56693)
- National Institute of Neurological Disorders and Stroke (1U01-NS33460)
- National Center for Research Resources (RR00095)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- orthostatic intolerance, orthostatic tachycardia, autonomic dysfunction, blood pressure regulation, young women, syncope, dizziness, pathophysiology, treatment options, differential diagnosis
- MeSH terms
- Adolescent, Adult, Female, Hemodynamics, Humans, Hypotension, Orthostatic, Posture, Tachycardia
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