Cited by 147Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesDementia and Cognitive Impairment Research

The DOI matches its Crossref record; 129 of the 129 references it cites were found in a registry or an index.

Clinically Significant Non-Major Depression: Old Concepts, New Insights

Lavretsky, Helen, Kumar, Anand·2002·The American Journal of Geriatric Psychiatry

DOI 10.1097/00019442-200205000-00003

Open this paper in CoChat — free account

Abstract

Clinically significant non-major depression has been underinvestigated despite its high prevalence and public health impact. Although there is an increasing recognition of the importance of non-major forms of depression, their nosological boundaries and neurobiological mechanisms remain largely unknown. The authors discuss the literature pertaining to the current concepts, phenomenology, neurobiology, and treatment approaches to geriatric non-major clinically significant depression. They examine the similarities and differences between various subtypes of depressive disorders and compare non-major, clinically significant depression in elderly patients with non-geriatric adult populations. They draw conclusions from the published literature and propose clinical criteria for the diagnosis of clinically significant non-major depression in elderly persons.

Integrity signals

Registry

Crossref · 10.1097/00019442-200205000-00003

Cites

129 of 129 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition
(2013) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9780890425596.893619 · Cited by 4,412
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.262.7.914 · Cited by 2,826
Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia
ROBINS, E., & GUZE, S. B. (1970) · American Journal of Psychiatry · doi:10.1176/ajp.126.7.983 · Cited by 2,243
The Functioning and Well-being of Depressed Patients: Results From the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.1989.03430070062031 · Cited by 2,130 · cited 2×
“Most patients with mental illness are seen exclusively in primary care medicine.(5,11,12) Primary care settings have therefore been the recent focus of studies of minor depression.”
Depression, Disability Days, and Days Lost From Work in a Prospective Epidemiologic Survey
Broadhead, W. E. (1990) · JAMA · doi:10.1001/jama.1990.03450190056028 · Cited by 1,232
Diagnostic and Statistical Manual of Mental Disorders
Preedy, V., & Watson, R. (2010) · Springer eBooks · doi:10.1007/978-0-387-78665-0_5485 · Cited by 1,146
Mental and Behavioral Disturbances in Dementia: Findings From the Cache County Study on Memory in Aging
Lyketsos, C. G., Steinberg, M., Tschanz, J. T., Norton, M. C., Steffens, D. C., & Breitner, J. C. S. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.708 · Cited by 1,144
Review of community prevalence of depression in later life
Beekman, A. T. F., Copeland, J. R. M., & Prince, M. J. (1999) · The British Journal of Psychiatry · doi:10.1192/bjp.174.4.307 · Cited by 1,139
Depression and cardiac mortality: results from a community-based longitudinal study.
Penninx, B., Beekman, A., Honig, A., Deeg, D., Schoevers, R., van Eijk, J., & van Tilburg, W. V. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.3.221 · Cited by 983
Diagnosis and Treatment of Depression in Late Life
Lebowitz, B. D. (1997) · JAMA · doi:10.1001/jama.278.14.1186 · Cited by 812
A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders
Judd, L. L., Akiskal, H. S., Maser, J. D., Zeller, P. J., Endicott, J., Coryell, W., Paulus, M. P., Kunovac, J. L., Leon, A. C., Mueller, T. I., et al. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.8.694 · Cited by 775
Common mental disorders : a bio-social model
Goldberg, D. P., & Huxley, P. J. (1992) · Cited by 757
A computerized psychiatric diagnostic system and case nomenclature for elderly subjects: GMS and AGECAT
Copeland, J. R. M., Dewey, M. E., & Griffiths‐Jones, H. M. (1986) · Psychological Medicine · doi:10.1017/s0033291700057779 · Cited by 753
Complicated grief and bereavement-related depression as distinct disorders: preliminary empirical validation in elderly bereaved spouses
(1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.1.22 · Cited by 736
The Natural History of Mental Disorder in Old Age
Roth, M. (1955) · Journal of Mental Science · doi:10.1192/bjp.101.423.281 · Cited by 723
Does old age reduce the risk of anxiety and depression? A review of epidemiological studies across the adult life span
Jorm, A. F. (2000) · Psychological Medicine · doi:10.1017/s0033291799001452 · Cited by 662
Epidemiology of dysphoria and depression in an elderly population
Blazer, D. G., & Williams, C. (1980) · American Journal of Psychiatry · doi:10.1176/ajp.137.4.439 · Cited by 638
Common mental disorders. A bio-social model
King, M. (1993) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(93)90179-j · Cited by 548
Socioeconomic burden of subsyndromal depressive symptoms and major depression in a sample of the general population
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.11.1411 · Cited by 538
Assessment in Geriatric Psychopharmacology
Hynie, S. (1986) · Neuropharmacology · doi:10.1016/0028-3908(86)90122-x · Cited by 498
Randomised controlled trial comparing problem solving treatment with amitriptyline and placebo for major depression in primary care
Mynors‐Wallis, L., Gath, D. H., Lloyd-Thomas, A. R., & Tomlinson, D. (1995) · BMJ · doi:10.1136/bmj.310.6977.441 · Cited by 491
Treatment of Dysthymia and Minor Depression in Primary Care: A Randomized Controlled Trial in Older Adults
Williams, Jr., Barrett, J., Oxman, T., Frank, E., Katon, W., Sullivan, M., Cornell, J., & Sengupta, A. (2000) · JAMA · doi:10.1001/jama.284.12.1519 · Cited by 460
Prevalence of Depression and Its Treatment in an Elderly Population: The Cache County Study
Steffens, D. C. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.6.601 · Cited by 456
The role and clinical significance of subsyndromal depressive symptoms (SSD) in unipolar major depressive disorder
Judd, L. L., Akiskal, H. S., & Paulus, M. P. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00055-4 · Cited by 444
Rates of dementia in three ethnoracial groups
Gurland, B. J., Wilder, D. E., Lantigua, R., Stern, Y., Chen, J., Killeffer, E. H. P., & Mayeux, R. P. (1999) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(199906)14:6 · Cited by 417
Age Differences in the Symptoms of Depression: A Latent Trait Analysis
Gallo, J. J., Anthony, J. C., & Muthén, B. (1994) · Journal of Gerontology · doi:10.1093/geronj/49.6.p251 · Cited by 391
Depression Among Institutionalized Aged: Assessment and Prevalence Estimation
Parmelee, P. A., Katz, I. R., & Lawton, M. P. (1989) · Journal of Gerontology · doi:10.1093/geronj/44.1.m22 · Cited by 372
Depression in hospitalized older patients with congestive heart failure
Koenig, H. G. (1998) · General Hospital Psychiatry · doi:10.1016/s0163-8343(98)80001-7 · Cited by 367
Consequences of major and minor depression in later life: a study of disability, well-being and service utilization
Beekman, A. T. F., Deeg, D. J. H., Braam, A. W., Smit, J. H., & van Tilburg, W. (1997) · Psychological Medicine · doi:10.1017/s0033291797005734 · Cited by 357
Depression, Falls, and Risk of Fracture in Older Women
Whooley, M. A. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.5.484 · Cited by 349
Chronically Depressed Mood and Cancer Risk in Older Persons
Penninx, B. W. J. H., Guralnik, J. M., Havlik, R. J., Pahor, M., Ferrucci, L., Cerhan, J. R., & Wallace, R. B. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.24.1888 · Cited by 347
The Course of Psychopathologic Features in Mild to Moderate Alzheimer Disease
Devanand, D. P. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830150083012 · Cited by 347
Depression in medically ill hospitalized older adults: prevalence, characteristics, and course of symptoms according to six diagnostic schemes
Koenig, H. G., George, L. K., Peterson, B. L., & Pieper, C. F. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.10.1376 · Cited by 335
The depressive spectrum: diagnostic classification and course
Angst, J., & Merikangas, K. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00057-8 · Cited by 302
Two-year longitudinal study of poststroke mood disorders: diagnosis and outcome at one and two years.
Robinson, R. G., BOLDUC, P. L., & Price, T. R. (1987) · Stroke · doi:10.1161/01.str.18.5.837 · Cited by 298
Clinical validity
Kendell, R. E. (1989) · Psychological Medicine · doi:10.1017/s0033291700011016 · Cited by 288
The Importance of Subsyndromal Depression in Older Primary Care Patients: Prevalence and Associated Functional Disability
Lyness, J. M., King, D. A., Cox, C., Yoediono, Z., & Caine, E. D. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01584.x · Cited by 278
Epidemiology and diagnosis of depression in late life.
Mulsant, B. H., & Ganguli, M. (1999) · PubMed · Cited by 259
Untitled work
(1999) · PubMed · Cited by 247
Depression and Disability Associated with Impaired Vision: The MoVIES Project
Rovner, B. W., & Ganguli, M. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb01080.x · Cited by 238
The course of depression in the elderly: a longitudinal community-based study in Australia
Henderson, A. S., Korten, A. E., Jacomb, P. A., Mackinnon, A. J., Jorm, A. F., Christensen, H. M., & Rodgers, B. (1997) · Psychological Medicine · doi:10.1017/s0033291796004199 · Cited by 215
Melancholia: A Disorder of Movement and Mood
(1996) · Cambridge University Press eBooks · doi:10.1017/cbo9780511759024 · Cited by 208
What is the Case?
(1957) · BMJ · doi:10.1136/bmj.1.5020.690 · Cited by 205
Depression in old age
Katona, C., & Watkin, V. (1991) · Reviews in Clinical Gerontology · doi:10.1017/s0959259800002884 · Cited by 203
Late-onset minor and major depression: early evidence for common neuroanatomical substrates detected by using MRI
Kumar, A., Jin, Z., Bilker, W. B., Udupa, J. K., & Gottlieb, G. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7654 · Cited by 189
Self-citation
The prevalence of depressive disorders and the distribution of depressive symptoms in later life: a survey using Draft ICD-10 and DSM-III-R
Henderson, A. S., Jorm, A. F., Mackinnon, A. J., Christensen, H. M., Scott, L. R., Korten, A. E., & Doyle, C. (1993) · Psychological Medicine · doi:10.1017/s0033291700025496 · Cited by 176
Depressive episodes and dysphoria resulting from conjugal bereavement in a prospective community sample
BRUCE, M. L., Kim, K., Leaf, P. J., & Jacobs, S. (1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.5.608 · Cited by 164
Minor depressive disorder and subsyndromal depressive symptoms: functional impairment and response to treatment
Rapaport, M. (1998) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00196-1 · Cited by 163
Depressive spectrum diagnoses
Angst, J., Sellar, R., & Merikangas, K. R. (2000) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(00)80007-3 · Cited by 158
The many faces of depression following spousal bereavement
Zisook, S., Paulus, M. P., Shuchter, S. R., & Judd, L. L. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00062-1 · Cited by 151
Delusions and hallucinations in Alzheimer's disease: prevalence and clinical correlates
Bassiony, M. M., Steinberg, M. S., Warren, A., Rosenblatt, A., Baker, A. S., & Lyketsos, C. G. (2000) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(200002)15:2 · Cited by 148
Apolipoprotein E Phenotype and Cognitive Decline in a Prospective Study of Elderly Community Women
Yaffe, K. S., Cauley, J. A., Sands, L. P., & Browner, W. S. (1997) · Archives of Neurology · doi:10.1001/archneur.1997.00550210044011 · Cited by 143
Two-year longitudinal study of post-stroke mood disorders: dynamic changes in correlates of depression at one and two years.
Parikh, R. M., Lipsey, J. R., Robinson, R. G., & Price, T. R. (1987) · Stroke · doi:10.1161/01.str.18.3.579 · Cited by 141
Regional cerebral glucose metabolism in late-life depression and Alzheimer disease: a preliminary positron emission tomography study.
Kumar, A., Newberg, A. B., Alavi, A. A., Berlin, J. A., Smith, R., & Reivich, M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.15.7019 · Cited by 134
Self-citation
Sadness in older persons: 13-year follow-up of a community sample in Baltimore, Maryland
Gallo, J. J., Rabins, P. V., & Anthony, J. C. (1999) · Psychological Medicine · doi:10.1017/s0033291798008083 · Cited by 122
Subthreshold depressions: clinical and polysomnographic validation of dysthymic, residual and masked forms
Akiskal, H. S., Judd, L. L., Gillin, J. C., & Lemmi, H. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00059-1 · Cited by 116
Depression and Medical Illness in Late Life: Report of a Symposium
Lyness, J. M., BRUCE, M. L., Koenig, H. G., Parmelee, P. A., Schulz, R., Lawton, M. P., & Reynolds, C. F. (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb02440.x · Cited by 108
APOE is a major susceptibility gene for Alzheimer’s disease
Roses, A. D., & Saunders, A. M. (1994) · Current Opinion in Biotechnology · doi:10.1016/0958-1669(94)90091-4 · Cited by 108
THE PSYCHOLOGICAL SYMPTOMS OF CONJUGAL BEREAVEMENT IN ELDERLY MEN OVER THE FIRST 13 MONTHS
Byrne, G. J., & Raphael, B. (1997) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(199702)12:2 · Cited by 106
Is there a difference between elderly and younger patients with regard to the symptomatology and aetiology of depression?
Gottfries, C. G. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199809005-00004 · Cited by 105
Family history of alcoholism and gender: their combined effects on DSM-IV alcohol dependence and major depression.
Dawson, D. A., & Grant, B. F. (1998) · Journal of Studies on Alcohol · doi:10.15288/jsa.1998.59.97 · Cited by 102
Is dysthymia a different disorder in the elderly?
Devanand, D. P., Nobler, M. S., Singer, T., Kiersky, J. E., Turret, N., Roose, S. P., & Sackeïm, H. A. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.11.1592 · Cited by 101
Why psychiatry is a branch of medicine
Guzé, S. B. (1992) · Medical Entomology and Zoology · Cited by 100
Problem-Solving Treatment: Evidence for Effectiveness and Feasibility in Primary Care
Mynors‐Wallis, L. (1996) · The International Journal of Psychiatry in Medicine · doi:10.2190/0hvy-cd2f-0kc7-fvtb · Cited by 95
Symptomatology of Late-Life Minor Depression Among Primary Care Patients
Oxman, T. E., Barrett, J. E., BARRETT, J. A., & Gerber, P. D. (1990) · Psychosomatics · doi:10.1016/s0033-3182(90)72191-3 · Cited by 94
A preliminary study of apolipoprotein E genotype and psychiatric manifestations of Alzheimer's disease
Ramachandran, G., Marder, K. S., Tang, M. X., Schofield, P. W., Chun, M. R., Dp, D., Stern, Y., & Mayeux, R. P. (1996) · Neurology · doi:10.1212/wnl.47.1.256 · Cited by 94
Depression in old age
Ernst, C., & Angst, J. (1995) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02191869 · Cited by 94
Subthreshold depressive and anxiety disorders in the elderly.
Heun, R., Papassotiropoulos, A., & Ptok, U. (2000) · European psychiatry · doi:10.1016/s0924-9338(00)00228-5 · Cited by 84
Designing an intervention to prevent suicide: PROSPECT (Prevention of Suicide in Primary Care Elderly: Collaborative Trial)
BRUCE, M. L., & Pearson, J. L. (1999) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.1999.1.2/mbruce · Cited by 83
Minor Depression: A Review of the Literature
Beck, D. A., & Koenig, H. G. (1996) · The International Journal of Psychiatry in Medicine · doi:10.2190/ac30-p715-y4td-j7d2 · Cited by 81
Why Psychiatry is a Branch of Medicine
Kroll, J. (1993) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199310000-00015 · Cited by 78
Association of the APOE ε4 allele with clinical subtypes of late life depression
Zubenko, G. S., Henderson, R., Stiffler, J. S., Stabler, S. M., Rosen, J., & Kaplan, B. B. (1996) · Biological Psychiatry · doi:10.1016/s0006-3223(96)00046-7 · Cited by 78
Minor Depression in a Cohort of Young Adults in Israel
Skodol, A. E. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950070034008 · Cited by 77
Minor Depression in the Aged
Tannock, C., & Katona, C. (1995) · Drugs & Aging · doi:10.2165/00002512-199506040-00003 · Cited by 76
Apolipoprotein E genotype and noncognitive symptoms in Alzheimer’s disease
Levy, M. L., Cummings, J. L., Fairbanks, L. A., Sultzer, D. L., & Small, G. W. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00041-9 · Cited by 71
Differences in Psychosocial and Health Correlates of Major and Minor Depression in Medically Ill Older Adults
Koenig, H. G. (1997) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1997.tb03200.x · Cited by 69
Early-Onset and Late-Onset Depression Are Independent of the Genetic Polymorphism of Apolipoprotein E
Papassotiropoulos, A., Bagli, M., Jessen, F., Rao, M. L., Schwab, S. G., & Heun, R. (1999) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000017129 · Cited by 67
Behavioral Differences Between Frontotemporal Dementia and Alzheimer's Disease: A Comparison on the BEHAVE-AD Rating Scale
Mendez, M. F., Perryman, K. M., Miller, B. L., & Cummings, J. L. (1998) · International Psychogeriatrics · doi:10.1017/s1041610298005262 · Cited by 64
Psychiatric Symptoms in Progressive Supranuclear Palsy
Menza, M. A., Cocchiola, J., & Golbe, L. I. (1995) · Psychosomatics · doi:10.1016/s0033-3182(95)71610-3 · Cited by 61
Subthreshold depression in the elderly: Qualitative or quantitative distinction?
Geiselmann, B., & Bauer, M. (2000) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(00)80006-1 · Cited by 60
Prevalence of depression in an elderly community sample: a comparison of GMS-AGECAT and DSM-IV diagnostic criteria
Newman, S. C., Sheldon, C. T., & Bland, R. C. (1998) · Psychological Medicine · doi:10.1017/s0033291798007442 · Cited by 58
Sub-typing depression, I. Is psychomotor disturbance necessary and sufficient to the definition of melancholia?
Parker, G., Hadzi-Pavlovic, D., Austin, M.-P., Mitchell, P., Wilhelm, K., Hickie, I., Boyce, P., & Eyers, K. (1995) · Psychological Medicine · doi:10.1017/s0033291700035066 · Cited by 57
The treatment effectiveness project. A comparison of the effectiveness of paroxetine, problem-solving therapy, and placebo in the treatment of minor depression and dysthymia in primary care patients: background and research plan
Barrett, J. E., Williams, J. W., Oxman, T. E., Katon, W. J., Frank, E., Hegel, M. T., Sullivan, M., & Schulberg, H. C. (1999) · General Hospital Psychiatry · doi:10.1016/s0163-8343(99)00023-7 · Cited by 55
Early Detection of Alzheimer's Disease by Combining Apolipoprotein E and Neuroimaginga
Small, G. W., Komo, S., Rue, A. L., Saxena, S., Phelps, M. E., Mazziotta, J. C., Saunders, A. M., Haines, J. L., Pericak‐Vance, M. A., & Roses, A. D. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb32600.x · Cited by 52
Mental well‐being in people with non‐insulin‐dependent diabetes
Viinamäki, H. T., NISKANEN, L. K., & Uusitupa, M. I. J. (1995) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1995.tb09602.x · Cited by 52
Cognitive Behavioral Therapy of Minor Depressive Symptoms in Elderly Chinese Americans: A Pilot Study
Dai, Y., Zhang, S., Yamamoto, J., Ao, M., Belin, T. R., Cheung, F. K., & Hifumi, S. S. (1999) · Community Mental Health Journal · doi:10.1023/a:1018763302198 · Cited by 52
A Longitudinal Study of Apolipoprotein-E Genotype and Depressive Symptoms in Community-Dwelling Older Adults
Mauricio, M., O'Hara, R. M., Yesavage, J. A., Friedman, L., KRAEMER, H. C., Water, M. V. D., & Murphy, G. M. (2000) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200008000-00003 · Cited by 51
Depressive personality in the relatives of outpatients with dysthymic disorder and episodic major depressive disorder and normal controls
Klein, D. N. (1999) · Journal of Affective Disorders · doi:10.1016/s0165-0327(98)00195-5 · Cited by 46
The Future of Psychosocial Treatments for Elderly Patients
Klausner, E. J., & Alexopoulos, G. S. (1999) · Psychiatric Services · doi:10.1176/ps.50.9.1198 · Cited by 46
Sub-typing depression, II. Clinical distinction of psychotic depression and non-psychotic melancholia
Parker, G. B., Hadži-Pavlović, D., Brodaty, H., Austin, M., Mitchell, P. B., Wilhelm, K. A., & Hickie, I. B. (1995) · Psychological Medicine · doi:10.1017/s0033291700035078 · Cited by 45
Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference
Mini, L. J. (1995) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199524310-00012 · Cited by 44
Apolipoprotein-E and White-Matter Hyperintensities in Late-Life Depression
Lavretsky, H., Lesser, I. M., Wohl, M. A., Miller, B. L., Mehringer, C. M., & Vinters, H. V. (2000) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200008000-00014 · Cited by 43
Self-citation
Pleomorphic expressions of unipolar depressive disease: summary of the 1996 CINP President's Workshop
Judd, L. L. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00064-5 · Cited by 42
Neurological correlates of depressive symptoms in Alzheimer's disease and vascular dementia
Simpson, S. (1999) · Journal of Affective Disorders · doi:10.1016/s0165-0327(98)00103-7 · Cited by 41
Serotonin transporter (5-HTT) gene polymorphism in psychogeriatric patients
Zill, P., Padberg, F., de Jonge, S., Hampel, H. J., Bürger, K., Stübner, S., Boetsch, T., Möller, H. J., Ackenheil, M., & Bondy, B. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)00994-0 · Cited by 36
Economic outcomes with antidepressant pharmacotherapy: a retrospective intent-to-treat analysis.
Sclar, D. A., Skaer, T. L., Robison, L. M., et al. (1998) · PubMed · Cited by 34
Minor and Subsyndromal Depression: Functional Disability Worth Treating
Rollman, B. L., & Reynolds, C. F. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01605.x · Cited by 33
Cerebral Blood Flow and Metabolism in Late-Life Depression and Dementia
Nobler, M. S., Pelton, G. H., & Sackeïm, H. A. (1999) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/089198879901200305 · Cited by 33
Association between Premorbid History of Depression and Current Depression in Alzheimer's Disease
Harwood, D. G., Barker, W., Ownby, R. L., et al. (1999) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/089198879901200206 · Cited by 32
Neuropsychiatric aspects of corticobasal degeneration.
Cummings, J. L., & Litvan, I. (2000) · PubMed · Cited by 31
A statistical analysis of the classification of depression in a mixed community and clinical sample
Blazer, D. G., Woodbury, M. A., Hughes, D., George, L. K., Mantón, K. G., Bachar, J. R., & Fowler, N. (1989) · Journal of Affective Disorders · doi:10.1016/0165-0327(89)90049-9 · Cited by 31
Inflationary Tendencies in Judging the Yield of Depression Research
van Praag, H. M. (1998) · Neuropsychobiology · doi:10.1159/000026492 · Cited by 30
Diagnosis, the Rate-Limiting Factor of Biological Depression Research
van Praag, H. M. (2008) · Neuropsychobiology · doi:10.1159/000119024 · Cited by 28
Behavioral complications and their treatment in Alzheimer's disease.
Devanand, D. P. (1997) · PubMed · Cited by 26
Philosophical Perspectives on Psychiatric Diagnostic Classification
Bell, C. C. (1994) · JAMA · doi:10.1001/jama.1994.03520220090039 · Cited by 25
The relationship between symptoms and diagnoses of minor psychiatric disorder in general practice
Grayson, D. A., Bridges, K. W., Duncan‐Jones, P., & Goldberg, D. P. (1987) · Psychological Medicine · doi:10.1017/s003329170000074x · Cited by 25
The significance of affective symptoms in old age : a follow-up study of one hundred patients
Post, F. (1962) · Oxford University Press eBooks · Cited by 24
Sub-typing depression, III. Development of a clinical algorithm for melancholia and comparison with other diagnostic measures
Parker, G. B., Hadži-Pavlović, D., Hickie, I. B., Brodaty, H., Boyce, P. M., Mitchell, P. B., & Wilhelm, K. A. (1995) · Psychological Medicine · doi:10.1017/s003329170003508x · Cited by 23
The treatment of emotional disorders in general practice: Psychological methods versus medication
Gath, D. H., & Catalan, J. M. (1986) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(86)90017-6 · Cited by 22
What Is a Case?
Kendell, R. E. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800280090012 · Cited by 21
Epidemiology of Mental Disorders in Middle Age and Late Life: Conceptual Issues
Gallo, J. J. (1995) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036188 · Cited by 19
Clinical Diagnosis: A Marker for Disease?
Tien, A. Y., & Gallo, J. J. (1997) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199712000-00004 · Cited by 18
Psychiatric diagnoses and inconsistent results of association studies in behavioral genetics
Sher, L. (2000) · Medical Hypotheses · doi:10.1054/mehy.1999.0022 · Cited by 17
The subaffective-character spectrum subtyping distinction in primary early-onset dysthymia: a clinical and family study
Anderson, R. L., Klein, D. N., Riso, L. P., et al. (1996) · Journal of Affective Disorders · doi:10.1016/0165-0327(95)00088-7 · Cited by 16
The Symptom Profile and Two-Year Course of Subsyndromal Depression in Spousally Bereaved Elders
Pasternak, R. E., Reynolds, C. F., Miller, M. D., Frank, E., Fasiczka, A. L., Prigerson, H. G., Mazumdar, S., & Kupfer, D. J. (1994) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199400230-00005 · Cited by 16
The DSM-IV (Depression) Classification: To Be or Not to Be?
VANPRAAG, H. (1990) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199003000-00001 · Cited by 16
The Public Health Model for Mental Health Care for the Elderly
Katz, I. R. (2000) · JAMA · doi:10.1001/jama.283.21.2844 · Cited by 14
Alzheimer's disease and related disorders annual
Hodges, J. R. (2001) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.70.6.821n · Cited by 13
Diagnoses of dementia and depression: a latent trait analysis of their performance
Grayson, D. A., Henderson, A. S., & Kay, D. W. K. (1987) · Psychological Medicine · doi:10.1017/s0033291700025903 · Cited by 13
[Effects of depression on physical health and mortality in the elderly. Longitudinal results of the LASA research].
Penninx, B. W. J. H., Beekman, A. T. F., Deeg, D., et al. (2000) · PubMed · Cited by 12
A Longitudinal Study of Apolipoprotein-E Genotype and Depressive Symptoms in Community-Dwelling Older Adults
Mauricio, M. (2000) · American Journal of Geriatric Psychiatry · doi:10.1176/appi.ajgp.8.3.196 · Cited by 12
What Should We Do About Undertreatment of Late Life Psychiatric Disorders in Primary Care?
Katz, I. R. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb01545.x · Cited by 10
Depression spectrum disease with and without depression in first-degree relatives
Rush, A. J., Feldman-Koffler, F., Weissenburger, J. E., et al. (1995) · Journal of Affective Disorders · doi:10.1016/0165-0327(95)00057-7 · Cited by 10
Apolipoprotein-E and White-Matter Hyperintensities in Late-Life Depression
Lavretsky, H. (2000) · American Journal of Geriatric Psychiatry · doi:10.1176/appi.ajgp.8.3.257 · Cited by 7
Self-citation
The Structure and Stability of Common Mental Disorders: The NEMESIS Study
Vollebergh, W. A. M., Iedema, J., Bijl, R. V., de Graaf, R., Smit, F., & Ormel, J. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.6.597 · Cited by 6
Untitled work
Gonzalez-Salvador (1999) · doi:10.1002/(sici)1099-1166(199909)14:9
Pharmacologic Efficacy in Neuropsychiatry
Rummans, T. A., Lauterbach, E. C., Coffey, C. E., Royall, D. R., Cummings, J. L., Salloway, S., Duffy, J., & Kaufer, D. (1999) · Journal of Neuropsychiatry · doi:10.1176/jnp.11.2.176
Major depression, minor depression, and double depression: are they distinct clinical entities?
Remick, R. A., Sadovnick, A. D., Lam, R. W., Zis, A. P., & Yee, I. M. L. (1996) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19960726)67:4

Research works printed but not linked: 3

Koscis, 1998, Geriatric dysthymia, J Clin Psychiatry, 59, 13
Remick, 1996, Major depression, minor depression, and double depression: are they distinct clinical entities?, Am J Med Genet, 67, 347, 10.1002/(SICI)1096-8628(19960726)67:4<347::AID-AJMG6>3.0.CO;2-J · DOI · Paper page
Beekman, 1997, Consequences of major and minor depression in later life: a study of disability, well-being, and service utilization, Psychol Med, 27, 1397, 10.1017/S0033291797005734 · DOI

Sorted by citations

Age- and gender-specific prevalence of depression in latest-life - Systematic review and meta-analysis
Luppa, M., Sikorski, C., Luck, T., Ehreke, L., Konnopka, A., Wiese, B., Weyerer, S., König, H.-H., & Riedel-Heller, S. G. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.11.033 · Cited by 855
A tune in "a minor" can "b major": a review of epidemiology, illness course, and public health implications of subthreshold depression in older adults
Meeks, T. W., Vahia, I. V., Lavretsky, H., Kulkarni, G., & Jeste, D. V. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.09.015 · Cited by 569
Self-citation
The prevalence of anxiety in older adults: Methodological issues and a review of the literature
Bryant, C., Jackson, H., & Ames, D. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.11.008 · Cited by 511
Subsyndromal depression in the elderly: underdiagnosed and undertreated
VanItallie, T. B. (2005) · Metabolism · doi:10.1016/j.metabol.2005.01.012 · Cited by 115
Health Service Utilization and Costs of Depressive Symptoms in Late Life - A Systematic Review
Luppa, M., Sikorski, C., Motzek, T., Konnopka, A., Konig, H.-H., & G. Riedel-Heller, S. (2012) · Current Pharmaceutical Design · doi:10.2174/138161212803523572 · Cited by 108

See all 147

Authors: Lavretsky, H., & Kumar, A.
Affiliations: University of California, Los Angeles (US)
Corresponding author: Lavretsky, Helen
ORCID: Lavretsky, Helen
Kumar, Anand
Venue: The American Journal of Geriatric Psychiatry
Publisher: Elsevier BV
Published: 2002-05
Volume: 10
Issue: 3
Pages: 239-255
ISSN: 1064-7481 (ISSN-L)
DOI: 10.1097/00019442-200205000-00003
OpenAlex: W1970129540
Cited by: 147
References: 129
Citations by year: 2026: 2 · 2025: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 3 · 2015: 10 · 2014: 8 · 2013: 4 · 2012: 11
FWCI: 6.66
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: American Journal of Geriatric Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (K02MH002043, R01MH061567, K23 MH 01948, KO2-MH02043, MH-55115, K23MH001948, R01MH055115, MH61567)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: geriatric depression, elderly patients, depression subtypes, neurobiology of depression, phenomenology of depression, depression treatment, diagnostic criteria, disease classification
MeSH terms: Aged, Aged, 80 and over, Aging, Depression, Female, Humans, Male, Middle Aged

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Clinically Significant Non-Major Depression: Old Concepts, New Insights

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks