The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Intestinal barrier function
Abstract
Intestinal barrier function regulates transport and host defense mechanisms at the mucosal interface with the outside world. Transcellular and paracellular fluxes are tightly controlled by membrane pumps, ion channels and tight junctions, adapting permeability to physiological needs. Food and microbial antigens are under constant surveillance of the mucosal immune system. Tolerance against commensals and immunity against pathogens require intact antigen uptake, recognition, processing and response mechanisms. Disturbance at any level, but particularly bacterial translocation due to increased permeability and breakdown of oral tolerance due to compromised epithelial and T cell interaction, can result in inflammation and tissue damage. New therapeutic approaches including probiotics and peptides to restore disrupted barrier function are evolving.
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Citations
Cites
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
Hooper, L. V., Wong, M. H., Thelin, A., Hansson, L., Falk, P. G., & Gordon, J. I. (2001) · Science · doi:10.1126/science.291.5505.881 · Cited by 2,202
Claudin-based tight junctions are crucial for the mammalian epidermal barrier
Furuse, M., Hata, M., Furuse, K., Yoshida, Y., Haratake, A., Sugitani, Y., Noda, T., Kubo, A., & Tsukita, S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110122 · Cited by 1,512
A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier
Lecuit, M., Vandormael-Pournin, S., Lefort, J., Huerre, M., Gounon, P., Dupuy, C., Babinet, C., & Cossart, P. (2001) · Science · doi:10.1126/science.1059852 · Cited by 633
Stamatovic, S. M., Keep, R. F., Kunkel, S. L., & Andjelkovic, A. V. (2003) · Journal of Cell Science · doi:10.1242/jcs.00755 · Cited by 381
Regulation of intestinal blood flow
Matheson, P. J., Wilson, M. A., & Garrison, R. N. (2000) · Journal of Surgical Research · doi:10.1006/jsre.2000.5862 · Cited by 296
Meddings, J. B., & Swain, M. G. (2000) · Gastroenterology · doi:10.1053/gast.2000.18152 · Cited by 269
V. Cholera: invasion of the intestinal epithelial barrier by a stably folded protein toxin
Lencer, W. I. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.280.5.g781 · Cited by 80
Cited by
Inflammatory bowel disease: cause and immunobiology
Baumgart, D. C., & Carding, S. R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60750-8 · Cited by 2,147
Self-citationJalili-Firoozinezhad, S., Prantil-Baun, R., Jiang, A., Potla, R., Mammoto, T., Weaver, J. C., Ferrante, T. C., Kim, H. J., Cabral, J. M. S., Levy, O., et al. (2018) · Cell Death & Disease · doi:10.1038/s41419-018-0304-8 · Cited by 209
High-fat-induced intestinal permeability dysfunction associated with altered fecal bile acids
Stenman, L. K. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i9.923 · Cited by 201
Mechanism and Intervention Measures of Iron Side Effects on the Intestine
Qi, X., Zhang, Y., Guo, H., Hai, Y., Luo, Y., & Yue, T. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1630599 · Cited by 142
Lambert, G. P. (2008) · Medicine and Sport Science · doi:10.1159/000151550 · Cited by 134
Yang, P., He, S., & Zheng, P. (2007) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04710.x · Cited by 89
Elamin, E., Masclee, A., Dekker, J., & Jonkers, D. (2014) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00236.2013 · Cited by 72
Modification of tight junction structure and permeability by nutritional means
Mullin, J. M., Skrovanek, S. M., & Valenzano, M. C. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04028.x · Cited by 21
Metadata
- Authors
- Baumgart, D. C., & Dignass, A. U.
- Venue
- Current Opinion in Clinical Nutrition and Metabolic Care
- Published
- 2002-11
- Volume
- 5
- Issue
- 6
- Pages
- 685-694
- ISSN
- 1363-1950 (ISSN-L)
- OpenAlex
- W2076872340
- Cited by
- 275
- References
- 7
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
