Cited by 108Muscle metabolism and nutritionClinical Nutrition and GastroenterologyNutrition and Health in Aging

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Regulation of skeletal muscle protein metabolism in catabolic states

Wolfe, Robert R·2005·Current Opinion in Clinical Nutrition and Metabolic Care

DOI 10.1097/00075197-200501000-00009

Open this paper in CoChat — free account

Abstract

PURPOSE OF REVIEW: This review highlights recent publications dealing with the nature of the in-vivo response of skeletal muscle to critical illness and approaches to attenuating this response. Studies focused on molecular mechanisms of muscle catabolism are not reviewed. RECENT FINDINGS: The general areas covered are the metabolic response to stress, particularly regarding the relationship between muscle protein breakdown, amino acid availability, and muscle protein synthesis. The impact of the profile of amino acids in the context of protein/amino acid intake is also discussed. Advances in our understanding of the hormonal response are considered, and use of insulin therapy to slow muscle catabolism is discussed. SUMMARY: Muscle catabolism is a fundamental response to severe stress, and the resulting amino acid efflux from muscle provides important precursors for protein synthesis in other parts of the body. The nature of this response (i.e. transport kinetics favoring efflux of amino acids from muscle) makes amelioration of the catabolic response of muscle with nutrition alone very difficult. Many approaches have been used to reverse catabolism, mostly involving various anabolic hormones. Recent studies using insulin therapy are particularly intriguing because of the low cost and powerful anabolic stimulus of insulin.

Integrity signals

Registry

Crossref · 10.1097/00075197-200501000-00009

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

RETRACTED: Effect of burn injury on glucocorticoid receptor binding activity in rat muscle
Sun, X., Fischer, D. R., Yang, M., & Tian, T. (2004) · Journal of Surgical Research · doi:10.1016/s0022-4804(03)00285-3 · Cited by 2
Retracted
Intensive insulin therapy in critically ill patients.
Van den Berghe, G., Wouters, P., Weekers, F., Verwaest, C., Bruyninckx, F., Schetz, M., Vlasselaers, D., Ferdinande, P., Lauwers, P., & Bouillon, R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011300 · Cited by 9,977
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539
Reversal of Catabolism by Beta-Blockade after Severe Burns
Herndon, D. N., Hart, D. W., Wolf, S. E., Chinkes, D. L., & Wolfe, R. R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010342 · Cited by 638
Self-citation
Orally Administered Leucine Stimulates Protein Synthesis in Skeletal Muscle of Postabsorptive Rats in Association with Increased eIF4F Formation
Anthony, J. C., Anthony, T. G., Kimball, S. R., Vary, T. C., & Jefferson, L. S. (2000) · Journal of Nutrition · doi:10.1093/jn/130.2.139 · Cited by 469
Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle
Biolo, G., Declan Fleming, R. Y., & Wolfe, R. R. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117731 · Cited by 442
Self-citation
Response of Protein and Urea Kinetics in Burn Patients to Different Levels of Protein Intake
Wolfe, R. R., Goodenough, R. D., Burke, J. F., & WOLFE, M. H. (1983) · Annals of Surgery · doi:10.1097/00000658-198302000-00007 · Cited by 270
Self-citation
Stimulation of Muscle Protein Synthesis by Long-Term Insulin Infusion in Severely Burned Patients
Sakurai, Y., Aarsland, A. A., Herndon, D. N., Chinkes, D. L., Pierre, E. J., Nguyen, T. T., Patterson, B. W., & Wolfe, R. R. (1995) · Annals of Surgery · doi:10.1097/00000658-199509000-00007 · Cited by 234
Self-citation
Insulin Treatment Improves the Systemic Inflammatory Reaction to Severe Trauma
Jeschke, M. G., Klein, D., & Herndon, D. N. (2004) · Annals of Surgery · doi:10.1097/01.sla.0000118569.10289.ad · Cited by 232
Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients
Gore, D. C., Chinkes, D. L., Hart, D. W., Wolf, S. E., Herndon, D. N., & Sanford, A. P. (2002) · Critical Care Medicine · doi:10.1097/00003246-200211000-00006 · Cited by 194

Show all 33 references

Research works printed but not linked: 3

Costelli, 2003, Curr Opin Clin Nutr Metab Care, 6, 407
Bergstrom, 1992, Miner Electrolyte Metab, 18, 280
Flakoll, 1993, Am J Physiol, 265, E715

Sorted by citations

Hypoalbuminemia: Pathogenesis and Clinical Significance
Soeters, P. B., Wolfe, R. R., & Shenkin, A. (2019) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1451 · Cited by 1,448
Self-citation
Human amyloid-β synthesis and clearance rates as measured in cerebrospinal fluid in vivo
Bateman, R. J., Munsell, L. Y., Morris, J. C., Swarm, R., Yarasheski, K. E., & Holtzman, D. M. (2006) · Nature Medicine · doi:10.1038/nm1438 · Cited by 599
Intensive care unit-acquired weakness
Griffiths, R., & Hall, J. B. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181cc4b53 · Cited by 277
Atrophy and Impaired Muscle Protein Synthesis during Prolonged Inactivity and Stress
Paddon-Jones, D., Sheffield-Moore, M., Cree, M. G., Hewlings, S. J., Aarsland, A., Wolfe, R. R., & Ferrando, A. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0651 · Cited by 254
Self-citation
Gender Differences in Pediatric Burn Patients
Jeschke, M. G., Mlcak, R. P., Finnerty, C. C., Norbury, W. B., Przkora, R., Kulp, G. A., Gauglitz, G. G., Zhang, X., & Herndon, D. N. (2008) · Annals of Surgery · doi:10.1097/sla.0b013e318176c4b3 · Cited by 172
Applications of stable, nonradioactive isotope tracers in in vivo human metabolic research
Kim, I.-Y., Suh, S., Lee, I., & Wolfe, R. R. (2016) · Experimental & Molecular Medicine · doi:10.1038/emm.2015.97 · Cited by 167
Self-citation
Hypocaloric vs Normocaloric Nutrition in Critically Ill Patients: A Prospective Randomized Pilot Trial
Petros, S., Horbach, M., Seidel, F., & Weidhase, L. (2016) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114528980 · Cited by 163
Current role of LC-MS(/MS) in doping control
Thevis, M., Thomas, A., & Schänzer, W. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-011-4859-9 · Cited by 138
Endocrine regulation of fetal skeletal muscle growth: impact on future metabolic health
Brown, L. D. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0567 · Cited by 149
Qualitative Determination of Synthetic Analogues of Insulin in Human Plasma by Immunoaffinity Purification and Liquid Chromatography−Tandem Mass Spectrometry for Doping Control Purposes
Thevis, M., Thomas, A., Delahaut, P., Bosseloir, A. L., & Schänzer, W. (2005) · Analytical Chemistry · doi:10.1021/ac050066i · Cited by 109
Skeletal muscle dysfunction in critical care: Wasting, weakness, and rehabilitation strategies
Puthucheary, Z., Harridge, S. D. R., & Hart, N. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181f2458d · Cited by 108
Postburn trauma insulin resistance and fat metabolism
Cree‐Green, M., & Wolfe, R. R. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00562.2007 · Cited by 107
Self-citation
Proteins and amino acids are fundamental to optimal nutrition support in critically ill patients
Weijs, P. J. M., Cynober, L., DeLegge, M. H., Kreymann, G., Wernerman, J., & Wolfe, R. R. (2014) · Critical Care · doi:10.1186/s13054-014-0591-0 · Cited by 106
Self-citation
Mass spectrometric determination of insulins and their degradation products in sports drug testing
Thevis, M., Thomas, A., & Schänzer, W. (2007) · Mass Spectrometry Reviews · doi:10.1002/mas.20154 · Cited by 102
Impact of Sarcopenic Obesity on Surgical Site Infection after Laparoscopic Total Gastrectomy
Nishigori, T., Tsunoda, S., Okabe, H., Tanaka, E. I., Hisamori, S., Hosogi, H., Shinohara, H., & Sakai, Y. (2016) · Annals of Surgical Oncology · doi:10.1245/s10434-016-5385-y · Cited by 101
Doping Control Analysis of Intact Rapid-Acting Insulin Analogues in Human Urine by Liquid Chromatography−Tandem Mass Spectrometry
Thevis, M., Thomas, A., Delahaut, P., Bosseloir, A. L., & Schänzer, W. (2006) · Analytical Chemistry · doi:10.1021/ac052095z · Cited by 95
Anabolic resistance in critically ill patients
Rennie, M. J. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181b6ec1f · Cited by 90
Metabolic and Nutrition Support in the Chronic Critical Illness Syndrome
Schulman, R. C., & Mechanick, J. I. (2012) · Respiratory Care · doi:10.4187/respcare.01620 · Cited by 83
Sarcopenic obesity is associated with adverse clinical outcome after cardiac surgery
Visser, M., van Venrooij, L. M. W., Vulperhorst, L., de Vos, R., Wisselink, W., van Leeuwen, P. A. M., & de Mol, B. A. J. M. (2012) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2011.12.001 · Cited by 83
Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates
Bateman, R. J., Munsell, L. Y., Chen, X., Holtzman, D. M., & Yarasheski, K. E. (2007) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2007.02.009 · Cited by 77
Current role of LC–MS(/MS) in doping control
Thevis, M., & Schänzer, W. (2007) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-007-1131-4 · Cited by 71
Nutritional interventions in critical illness
Powell-Tuck, J. (2007) · Proceedings of The Nutrition Society · doi:10.1017/s0029665107005253 · Cited by 70
Nutritional management of patients with urea cycle disorders
Singh, R. H. (2007) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-007-0718-4 · Cited by 70
Effects of pharmacological interventions on muscle protein synthesis and breakdown in recovery from burns
Diaz, E. C., Herndon, D. N., Porter, C. C., Sidossis, L. S., Suman-Vejas, O. E., & Børsheim, E. (2014) · Burns · doi:10.1016/j.burns.2014.10.010 · Cited by 67
Metabolic and Endocrine Considerations After Burn Injury
Williams, F. N., & Herndon, D. N. (2017) · Clinics in Plastic Surgery · doi:10.1016/j.cps.2017.02.013 · Cited by 67
Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides
Cree‐Green, M., Paddon‐Jones, D., Newcomer, B. R., Rønsen, O., Aarsland, A. A., Wolfe, R. R., & Ferrando, A. A. (2009) · Metabolism · doi:10.1016/j.metabol.2009.09.014 · Cited by 61
Self-citation
Doping control analysis of insulin and its analogues in equine urine by liquid chromatography–tandem mass spectrometry
Ho, E. N. M., Wan, T. S. M., Wong, A. S. Y., Lam, K. K. H., & Stewart, B. D. (2011) · Journal of Chromatography A · doi:10.1016/j.chroma.2010.12.052 · Cited by 60
How Does Physical Activity Modulate Hormone Responses?
Mennitti, C., Farina, G., Imperatore, A., Fonzo, G. D., Gentile, A., Civita, E. L., Carbone, G., Simone, R. R. D., Iorio, M. R. D., Tinto, N., et al. (2024) · Biomolecules · doi:10.3390/biom14111418 · Cited by 79
Nutrition Support and the Chronic Critical Illness Syndrome
Hollander, J. M., & Mechanick, J. I. (2006) · Nutrition in Clinical Practice · doi:10.1177/0115426506021006587 · Cited by 55
Insulin
Thevis, M., Thomas, A., & Schänzer, W. (2009) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-79088-4_10 · Cited by 56
Prioritization of skeletal muscle growth for emergence from hibernation
Hindle, A. G., Otis, J. P., Epperson, L. E., Hornberger, T. A., Goodman, C. A., Carey, H. V., & Martin, S. L. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.109512 · Cited by 50
Doping control analysis of insulin and its analogues in equine plasma by liquid chromatography–tandem mass spectrometry
Ho, E. N. M., Wan, T. S. M., Wong, A. S. Y., Lam, K. K. H., & Stewart, B. D. (2008) · Journal of Chromatography A · doi:10.1016/j.chroma.2008.04.060 · Cited by 50
Protein Requirements of the Critically Ill Pediatric Patient
Coss‐Bu, J. A., Hamilton‐Reeves, J. M., Patel, J. J., Morris, C. R., & Hurt, R. T. (2017) · Nutrition in Clinical Practice · doi:10.1177/0884533617693592 · Cited by 44
New drugs and methods of doping and manipulation
Thevis, M., Kohler, M., & Schänzer, W. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2007.11.003 · Cited by 41
Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs
Orellana, R. A., Suryawan, A., Wilson, F. A., Gazzaneo, M. C., Fiorotto, M. L., Nguyen, H. V., & Davis, T. A. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00259.2011 · Cited by 38
Assessment of body composition and impact of sarcopenia and sarcopenic obesity in patients with gastric cancer
Nishigori, T., Obama, K., & Sakai, Y. (2020) · Translational Gastroenterology and Hepatology · doi:10.21037/tgh.2019.10.13 · Cited by 39
Endogenous Glucose Production in Critical Illness
Al‐Yousif, N., Rawal, S., Jurczak, M. J., Mahmud, H., & Shah, F. A. (2021) · Nutrition in Clinical Practice · doi:10.1002/ncp.10646 · Cited by 40
Mass spectrometric identification of peptide hormones in doping-control analysis
Thevis, M., & Schänzer, W. (2007) · The Analyst · doi:10.1039/b618748j · Cited by 35
Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation
Orellana, R. A., Jeyapalan, A. S., Escobar, J., Frank, J. W., Nguyen, H. V., Suryawan, A., & Davis, T. A. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00146.2007 · Cited by 34
Effects of dietary amino acid levels and ambient temperature on mixed muscle protein turnover in Pectoralis major during finisher feeding period in two broiler lines
Maharjan, P., Mullenix, G. J., Hilton, K., Beitia, A., Weil, J. T., Suesuttajit, N., Martinez, D. A., Umberson, C., England, J. A., Caldas, J. V., et al. (2020) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13363 · Cited by 37
Protein Requirements for Critically Ill Patients With Renal and Liver Failure
Patel, J. J., McClain, C. J., Sarav, M., Hamilton‐Reeves, J. M., & Hurt, R. T. (2017) · Nutrition in Clinical Practice · doi:10.1177/0884533616687501 · Cited by 36
Oxidative stress and skeletal muscle in exercise
Castrogiovanni, P., & Imbesi, R. (2012) · Italian Journal of Anatomy and Embryology · doi:10.36253/ijae-1128 · Cited by 33
Full versus Trophic Feeds in Critically Ill Adults with High and Low Nutritional Risk Scores: A Randomized Controlled Trial
Wang, C.-Y., Fu, P., Chao, W., Wang, W.-N., Chen, C., & Huang, Y. (2020) · Nutrients · doi:10.3390/nu12113518 · Cited by 35
Impact of sarcopenic overweight on the outcomes after living donor liver transplantation
Hammad, A., Kaido, T., Hamaguchi, Y., Okumura, S., Kobayashi, A., Shirai, H., Kamo, N., Yagi, S., & Üemoto, S. (2017) · HepatoBiliary Surgery and Nutrition · doi:10.21037/hbsn.2017.02.02 · Cited by 32
Modulation of the hypermetabolic response after burn injury
Norbury, W. B., & Herndon, D. N. (2007) · Elsevier eBooks · doi:10.1016/b978-1-4160-3274-8.50034-9 · Cited by 30
Modulation of the hypermetabolic response after burn injury
Gauglitz, G. G., Finnerty, C. C., Herndon, D. N., Williams, F. N., & Jeschke, M. G. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-2786-9.00030-8 · Cited by 31
The impact of preoperative skeletal muscle mass index-defined sarcopenia on postoperative complications and survival in gastric cancer: An updated meta-analysis
Liu, C., Li, Y., Xu, Y., & Hou, H. (2024) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2024.109569 · Cited by 30
Anabolic and anticatabolic agents used in burn care: What is known and what is yet to be learned
Gus, E. I., Shahrokhi, S., & Jeschke, M. G. (2019) · Burns · doi:10.1016/j.burns.2018.03.009 · Cited by 29
Moderate glucose control results in less negative nitrogen balances in medical intensive care unit patients: a randomized, controlled study
Hsu, C.-W., Sun, S., Lin, S.-L., Huang, H.-H., & Wong, K.-F. (2012) · Critical Care · doi:10.1186/cc11299 · Cited by 29
Development and current use of parenteral nutrition in critical care – an opinion paper
Berger, M. M., & Pichard, C. (2014) · Critical Care · doi:10.1186/s13054-014-0478-0 · Cited by 29
Parenteral nutrition in the ICU: Lessons learned over the past few years
Berger, M. M., & Pichard, C. (2018) · Nutrition · doi:10.1016/j.nut.2018.08.012 · Cited by 29
Early or Late Feeding after ICU Admission?
Blaser, A. R., & Berger, M. M. (2017) · Nutrients · doi:10.3390/nu9121278 · Cited by 28
Doping im Sport
Schänzer, W., & Thevis, M. (2007) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-007-1079-3 · Cited by 25
The effect of protein intake and resistance training on muscle mass in acutely ill old medical patients – A randomized controlled trial
Buhl, S. F., Andersen, A. L., Andersen, J. R., Andersen, O., Jensen, J. B., Rasmussen, A. M. L., Pedersen, M. M., Damkjær, L., Gilkes, H., & Petersen, J. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2015.02.015 · Cited by 22
Impacts of microgravity on amino acid metabolism during spaceflight
Dickerson, B. L., Sowinski, R. J., Kreider, R. B., & Wu, G. (2023) · Experimental Biology and Medicine · doi:10.1177/15353702221139189 · Cited by 20
Chocolate Milk versus carbohydrate supplements in adolescent athletes: a field based study
Born, K. A., Dooley, E. E., Cheshire, P. A., McGill, L. E., Cosgrove, J. M., Ivy, J. L., & Bartholomew, J. B. (2019) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-019-0272-0 · Cited by 19
Evaluation of immunoassays for the measurement of insulin and C-peptide as indirect biomarkers of insulin misuse in sport: Values in selected population of athletes
Abellán, R., Ventura, R., Palmi, I., Carlo, S. D., Giovannandrea, R. D., Bellver, M., Olive, R., Pascual, J. A., Pacifici, R., Segura, J., et al. (2009) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2008.12.037 · Cited by 18
Sarcopenia adversely impacts postoperative complications in living-donor liver transplantation recipients
Wu, M.-Y., Lim, W.-X., Cheng, Y., Chang, C.-D., Hsu, H., Lin, C., Chen, C., Chang, W.-C., Yu, C., Tsang, L. L., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-98399-6 · Cited by 17
High-Protein Formulas
Brown, L. D., Hendrickson, K., Masor, M. L., & Hay, W. W. (2014) · Clinics in Perinatology · doi:10.1016/j.clp.2014.02.002 · Cited by 17
Considerations in the Difficult-to-Manage Urea Cycle Disorder Patient
Lee, B., Singh, R. H., Rhead, W. J., King, L. S., Smith, W. E., & Summar, M. L. (2005) · Critical Care Clinics · doi:10.1016/j.ccc.2005.05.001 · Cited by 17
Requirements of Energy, Carbohydrates, Proteins and Fats for Athletes
Kerksick, C. M., & Kulovitz, M. (2013) · Nutrition and Enhanced Sports Performance · doi:10.1016/b978-0-12-396454-0.00036-9 · Cited by 16
Detection of recombinant insulins in human urine by liquid chromatography–electrospray ionization tandem mass spectrometry after immunoaffinity purification based on monolithic microcolumns
Mazzarino, M., Senofonte, M., Martinelli, F., de la Torre, X., & Botrè, F. (2019) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-019-02203-4 · Cited by 16
Effects of branched amino acids supplementation in malnourished elderly with catabolic status
Bonnefoy, M., Laville, M., Écochard, R., Jusot, J. F., Normand, S., Maillot, S., Lebreton, B., & Jauffret, M. (2010) · The journal of nutrition health & aging · doi:10.1007/s12603-010-0090-1 · Cited by 17
Doping detection in animals: A review of analytical methodologies published from 1990 to 2019
Moreira, F., Carmo, H., de Pinho, P. G., & Bastos, M. D. L. (2021) · Drug Testing and Analysis · doi:10.1002/dta.2999 · Cited by 13
The use of anabolic agents in catabolic states.
Demling, R. H. (2007) · PubMed Central · Cited by 12
Hyperinsulinemic-normoglycemic clamp administered together with amino acids induces anabolism after cardiac surgery
Codère-Maruyama, T., Schricker, T., Tim, D. S., Wykes, L., Nitschmann, E. P., Guichon, C., Kristof, A. S., & Hatzakorzian, R. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00334.2016 · Cited by 11
Metabolic alterations in the critically ill child: a narrative review
Orellana, R. A., & Coss‐Bu, J. A. (2021) · Pediatric Medicine · doi:10.21037/pm-20-64 · Cited by 12
Effects of dietary energy levels on Pectoralis major mixed muscle protein turnover and body composition in two broiler lines housed in different grow‐out environments
Maharjan, P., Mullenix, G. J., Hilton, K., Weil, J. T., Beitia, A., Caldas, J. V., Naranjo, V. D., & Coon, C. N. (2021) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13467 · Cited by 12
High-dose insulin administration is associated with hypoaminoacidemia during cardiac surgery
Hatzakorzian, R., Carvalho, G., Bui, H., Sato, T., Wykes, L., Tim, D. S., & Schricker, T. (2011) · Metabolism · doi:10.1016/j.metabol.2011.03.007 · Cited by 10
Glucose and insulin administration while maintaining normoglycemia inhibits whole body protein breakdown and synthesis after cardiac surgery
Hatzakorzian, R., Tim, D. S., Wykes, L., Hülshoff, A., Bui, H., Nitschmann, E. P., Lattermann, R., & Schricker, T. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00175.2014 · Cited by 10
Isotope-dilution liquid chromatography-tandem mass spectrometry for sensitive quantification of human insulin in serum using derivatization-technique
Sakaguchi, Y., Kinumi, T., & Takatsu, A. (2017) · Analytical Biochemistry · doi:10.1016/j.ab.2017.08.019 · Cited by 10
Requirements of Proteins, Carbohydrates, and Fats for Athletes
Kerksick, C. M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813922-6.00038-2 · Cited by 18
Coumestrol attenuates dexamethasone-induced muscle atrophy via AMPK-FOXO1/3 signaling
Hah, Y., Lee, W. K., Lee, S.-Y., Seo, J.-H., Kim, E. J., Choe, Y.-I., Kim, S. G., & Yoo, J. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105387 · Cited by 8
Nutritional Assessment and Management of the Malnourished Patient
Mason, J. B. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6189-2.00004-4 · Cited by 7
Urinary metabolite model to predict the dying process in lung cancer patients
Coyle, S., Chapman, E. A., Hughes, D. M., Baker, J., Slater, R., Davison, A., Norman, B. P., Roberts, I., Nwosu, A. C., Gallagher, J. A., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00764-3 · Cited by 6
Inner Abdominal Fat and Psoas Muscle as Predictive Factors for the Outcome After Liver Transplant
Malamutmann, E., Frenzen, A., Karadag, H.-I., Emre, A., Klein, C., Paul, A., & Oezcelik, A. (2021) · Experimental and Clinical Transplantation · doi:10.6002/ect.2020.0265 · Cited by 6
Basic metabolism: protein
Emery, P. W. (2012) · Surgery (Oxford) · doi:10.1016/j.mpsur.2012.02.008 · Cited by 6
Basic metabolism: protein
Emery, P. W. (2015) · Surgery (Oxford) · doi:10.1016/j.mpsur.2015.01.008 · Cited by 5
Nutritional Management in a Patient with Citrullinemia Type 1
Kang, H., Kim, M., & Lee, J. (2021) · Clinical Nutrition Research · doi:10.7762/cnr.2021.10.3.268 · Cited by 5
Adequacy of prescribed caloric and protein intake and reduction of mortality in critically ill patients with body mass indices <30 kg/m2
Tsai, J., Chang, W., Sheu, C., Wu, Y., Chen, M.-A., Hsu, Y.-H., Lee, C.-Y., Chang, C.-I., Wang, T., & Huang, M. (2021) · Nutrition · doi:10.1016/j.nut.2021.111529 · Cited by 5
Association between enteral nutrition support and neurological outcome in patients with acute intracranial haemorrhage: A retrospective cohort study
Cheng, X., Ru, W., Du, K., Jiang, X., Hu, Y., Zhang, W., Xu, Y., & Shen, Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-53100-w · Cited by 4
Is slower advancement of enteral feeding superior to aggressive full feeding regimens in the early phase of critical illness
Lheureux, O., & Preiser, J. (2019) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000626 · Cited by 4
Computational modeling to predict nitrogen balance during acute metabolic decompensation in patients with urea cycle disorders
MacLeod, E., Hall, K. D., & McGuire, P. J. (2015) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-015-9882-0 · Cited by 4
A method to determine the kinetics of multiple proteins in human infants with respiratory distress syndrome
Bereman, M. S., Tomazela, D. M., Heins, H. B., Simonato, M., Cogo, P. E., Hamvas, A., Patterson, B. W., Cole, F. S., & MacCoss, M. J. (2012) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-012-5953-3 · Cited by 4
Emergency Management of Inherited Metabolic Disorders
Mofidi, S., & Kronn, D. (2009) · Topics in Clinical Nutrition · doi:10.1097/tin.0b013e3181c622c5 · Cited by 4
The underlying metabolism of hypoalbuminemia and its clinical effects
Soeters, P. B., & de Leeuw, P. W. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820205-0.00010-4 · Cited by 3
A Dual Functional-Group Derivatization Liquid Chromatography–Tandem Mass Spectrometry Method: Application for Quantification of Human Insulin
Sakaguchi, Y., Kinumi, T., & Takatsu, A. (2022) · Chromatographia · doi:10.1007/s10337-022-04136-0 · Cited by 3
Impact of Infection–Nutrient Interactions in Infants, Children, and Adolescents
Orellana, R. A., & Coss‐Bu, J. A. (2014) · CRC Press eBooks · doi:10.1201/b17311-15 · Cited by 3
Traitement nutritionnel du grand brûlé
Berger, M. M., & Que, Y. (2009) · Réanimation · doi:10.1016/j.reaurg.2009.09.001 · Cited by 2
Modulación de la respuesta hipermetabólica después de las quemaduras
Norbury, W. B. (2009) · Elsevier eBooks · doi:10.1016/b978-84-458-1938-8.50022-2 · Cited by 2
Nutrition Support for the Critically Ill Infant Post Cardiac Surgery
Larsen, B. K., & Beggs, M. R. (2015) · Springer eBooks · doi:10.1007/978-1-4614-7836-2_143 · Cited by 2
Clofazimine-Mediated, Age-Related Changes in Skeletal Muscle Mitochondrial Metabolites
Diaz‐Espinosa, J., Stringer, K. A., & Rosania, G. R. (2023) · Metabolites · doi:10.3390/metabo13050671 · Cited by 2
Metabolic Adaptation in Hibernating American Black Bears: Exploring Immobilization Protection with Mass Spectral Data and Computational Methods
Anderson, M., Lusczek, B., Murray, K., Lassen, J. F., Ikramuddin, S., & Iles, T. L. (2023) · Lecture notes in networks and systems · doi:10.1007/978-3-031-47451-4_11 · Cited by 1
Nutrition, immunité et inflammation
Vasson, M., & Reimund, J. (2007) · Springer eBooks · doi:10.1007/978-2-287-33475-7_34 · Cited by 2
Nutrition Support for the Critically Ill Infant Post-Cardiac Surgery
Larsen, B. K., & Beggs, M. R. (2014) · Springer eBooks · doi:10.1007/978-1-4614-8503-2_143-1 · Cited by 1
Protein Metabolism and Glutamine Supplementation in Stress Condition
An, S. H. (2014) · Journal of Clinical Nutrition · doi:10.15747/jcn.2014.6.2.56 · Cited by 1
Muscle Hypertrophy
Alway, S. E. (2006) · CRC Press eBooks · doi:10.1201/9781420019322.ch20 · Cited by 1
Structure Characterization of Low Molecular Weight Target Analytes: Electrospray Ionization
Thevis, M. (2010) · Wiley eBooks · doi:10.1002/9780470626634.ch4 · Cited by 1
Pathophysiologie des operativen Traumas
Hartl, W. H. (2012) · Chirurgie Basisweiterbildung · doi:10.1007/978-3-642-23804-8_2
Protein metabolism and nutritional requirements in critically ill children = Eiwitmetabolisme en voedingsbehoefte van ernstig zieke kinderen
van Waardenburg, D. A. (2008) · Research Publications (Maastricht University) · doi:10.26481/dis.20080918dw

Authors: Wolfe, R. R.
Affiliations: The University of Texas Medical Branch at Galveston (US)
Corresponding author: Wolfe, Robert R
ORCID: Wolfe, Robert R
Venue: Current Opinion in Clinical Nutrition and Metabolic Care
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2005-01
Volume: 8
Issue: 1
Pages: 61-65
ISSN: 1363-1950 (ISSN-L)
DOI: 10.1097/00075197-200501000-00009
OpenAlex: W2016803694
Cited by: 108
References: 33
Citations by year: 2025: 2 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 12 · 2020: 3 · 2019: 5 · 2018: 3 · 2017: 6 · 2016: 3 · 2015: 4 · 2014: 11 · 2013: 1 · 2012: 9
FWCI: 0.45
Type: journal article
Language: en
Open access: closed
Locations: Current Opinion in Clinical Nutrition & Metabolic Care (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Keywords: skeletal muscle protein metabolism, muscle catabolism, critical illness, amino acid availability, muscle protein synthesis, amino acid efflux, insulin therapy, anabolic hormones, stress response, nutritional support, catabolic state
MeSH terms: Amino Acids, Humans, Insulin, Muscle Proteins, Stress, Physiological, Muscle, Skeletal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Regulation of skeletal muscle protein metabolism in catabolic states

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks