The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
The Impact of Osteoarthritis: Implications for Research
Abstract
Osteoarthritis, the clinical syndrome of joint pain and dysfunction caused by joint degeneration, affects more people than any other joint disease. There are no consistently effective methods for preventing osteoarthritis or slowing its progression, and symptomatic treatments provide limited benefit for many patients. Osteoarthritis disables about 10% of people who are older than 60 years, compromises the quality of life of more than 20 million Americans, and costs the United States economy more than $60 billion per year. The incidence of osteoarthritis rises precipitously with age; as a result, the prevalence and burden of this disorder is increasing rapidly. Study of the patterns osteoarthritis incidence and prevalence shows that it occurs frequently in the hand, foot, knee, spine and hip, but rarely in the ankle, wrist, elbow, and shoulder, and the most important universal risk factors are age, excessive joint loading, and joint injury. Analysis of the impact of osteoarthritis raises questions that include: Why does the incidence increase progressively with age? Why are some joints rarely affected? How do mechanical forces cause joint degeneration? What biologic and mechanical factors slow or accelerate the rate of joint degeneration? Answering these questions could lead to effective methods of preventing osteoarthritis and slowing its progression.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Matta, J. M. (1996) · PubMed · Cited by 1,392
Intra-articular fractures of the distal end of the radius in young adults.
Knirk, J. L., & Jupiter, J. B. (1986) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-198668050-00003 · Cited by 1,360
Obesity and Knee Osteoarthritis: The Framingham Study
Felson, D. T., Anderson, J. J., Naimark, A., Walker, A. M., & Meenan, R. F. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-1-18 · Cited by 1,080
Role of Subchondral Bone in the Initiation and Progression of Cartilage Damage
RADIN, E. L., & ROSE, R. M. (1986) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-198612000-00005 · Cited by 1,075
Oliveria, S. A., Felson, D. T., Reed, J. I., Cirillo, P. A., & Walker, A. M. (1995) · Arthritis & Rheumatism · doi:10.1002/art.1780380817 · Cited by 903
ANDERSON, J. J., & FELSON, D. T. (1988) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114939 · Cited by 892
Weight Loss Reduces the Risk for Symptomatic Knee Osteoarthritis in Women: The Framingham Study
Felson, D. T., Zhang, Y., Anthony, J. M., Naimark, A., & Anderson, J. J. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-116-7-535 · Cited by 862
BUCKWALTER, J. A., & MANKIN, H. J. (1997) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-199704000-00022 · Cited by 755
Self-citationFelson, D. T., Zhang, Y., Hannan, M. T., Naimark, A., Weissman, B. N., Aliabadi, P., & Levy, D. (1995) · Arthritis & Rheumatism · doi:10.1002/art.1780381017 · Cited by 728
Joint Injury in Young Adults and Risk for Subsequent Knee and Hip Osteoarthritis
Gelber, A. C., Hochberg, M. C., Mead, L. A., Wang, N.-Y., Wigley, F. M., & Klag, M. J. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-133-5-200009050-00007 · Cited by 676
Cited by
The epidemiology and impact of pain in osteoarthritis
Neogi, T. (2013) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2013.03.018 · Cited by 1,730
Lamo-Espinosa, J. M., Blanco, J. F., Sánchez, M., Moreno, V., Granero-Moltó, F., Sánchez-Guijo, F., Crespo-Cullel, Í., Mora, G., San Vicente, D. D., Pompei-Fernández, O., et al. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02530-6 · Cited by 118
Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study
Zhai, G., Aviv, A., Hunter, D. J., Hart, D. J., Gardner, J. P., Kimura, M., Lu, X., Valdes, A. M., & Spector, T. D. (2006) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.056903 · Cited by 72
Awad, M. E., Hussein, K. A., Helwa, I., Abdelsamid, M. F., Aguilar-Perez, A., Mohsen, I., Hunter, M., Hamrick, M. W., Isales, C. M., Elsalanty, M., et al. (2019) · Stem Cells International · doi:10.1155/2019/3826054 · Cited by 39
Metadata
- Authors
- Buckwalter, J. A., Saltzman, C., & Brown, T.
- Venue
- Clinical Orthopaedics & Related Research
- Published
- 2004-10
- Volume
- 427
- Issue
- 427 Suppl
- Pages
- S6-S15
- ISSN
- 0009-921X (ISSN-L)
- OpenAlex
- W2084610846
- Cited by
- 678
- References
- 63
- FWCI
- 14.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Impact of Osteoarthritis: Implications for Research. https://app.cochat.ai/papers/10.1097/01.blo.0000143938.30681.9d
- The paper
- Buckwalter, J. A., Saltzman, C., & Brown, T. (2004). The Impact of Osteoarthritis: Implications for Research. Clinical Orthopaedics & Related Research. https://doi.org/10.1097/01.blo.0000143938.30681.9d
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
