The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
The impact of delirium on the survival of mechanically ventilated patients*
Abstract
OBJECTIVES: To revalidate a means of assessing delirium in intensive care unit patients and to investigate the independent effect of delirium on the mortality of mechanically ventilated patients. DESIGN: A prospective cohort study. SETTING: A 37-bed medical intensive care unit of a tertiary care hospital. PATIENTS: Subjects were 102 of 131 consecutive mechanically ventilated patients. MEASUREMENTS: All the enrolled patients were assessed for delirium using the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Mortality rate were compared between patients with or without delirium, and the predictors of death were investigated. RESULTS: The two CAM-ICU assessors' sensitivities in diagnosing delirium compared with reference standard were 91% and 95%, whereas their specificities were both 98%. They also demonstrated high interrater reliability with kappa statistics of 0.91. Delirium was present in 22 of 102 (22%) patients in the first 5 days. The delirious patients had higher intensive care unit mortality rate than nondelirious patients (63.6% vs. 32.5%, respectively), with a hazard ratio of 2.57 (95% confidence interval, 1.56-8.15). In multivariate analysis, delirium (odds ratio, 13.0; 95% confidence interval, 2.69-62.91), shock (odds ratio, 12.91; 95% confidence interval, 2.93-56.92), and illness severity (odds ratio, 9.61; 95% confidence interval, 2.24-41.18) were independent predictors of mortality. CONCLUSIONS: This study confirms previous work showing that delirium is an independent predictor for increased mortality among mechanically ventilated patients.
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Cites
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Clarifying Confusion: The Confusion Assessment Method: A New Method for Detection of Delirium
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The APACHE III Prognostic System
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A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
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Intensive Care Delirium Screening Checklist: evaluation of a new screening tool
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Cited by
Inouye, S. K., Westendorp, R. G., & Saczynski, J. S. (2014) · The Lancet · doi:10.1016/s0140-6736(13)60688-1 · Cited by 3,722
Schweickert, W. D., Pohlman, M. C., Pohlman, A. S., Nigos, C., Pawlik, A. J., Esbrook, C. L., Spears, L., Miller, M., Franczyk, M., Deprizio, D., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60658-9 · Cited by 3,339
Pandharipande, P. P., Pun, B. T., Herr, D. L., Maze, M., Girard, T. D., Miller, R. R., Shintani, A. K., Thompson, J. L., Jackson, J. C., Deppen, S. A., et al. (2007) · JAMA · doi:10.1001/jama.298.22.2644 · Cited by 1,451
Incidence, risk factors and consequences of ICU delirium
Ouimet, S., Kavanagh, B. P., Gottfried, S. B., & Skrobik, Y. (2007) · Intensive Care Medicine · doi:10.1007/s00134-006-0399-8 · Cited by 972
The Confusion Assessment Method: A Systematic Review of Current Usage
Wei, L. A., Fearing, M. A., Sternberg, E. J., & Inouye, S. K. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01674.x · Cited by 796
Metadata
- Authors
- Lin, S.-M., Liu, C.-Y., Wang, C.-H., Lin, H.-C., Huang, C.-D., Huang, P.-Y., Fang, Y.-F., Shieh, M.-H., & Kuo, H.-P.
- Venue
- Critical Care Medicine
- Published
- 2004-11
- Volume
- 32
- Issue
- 11
- Pages
- 2254-2259
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W188497340
- Cited by
- 451
- References
- 29
- FWCI
- 12.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lin, S.-M., Liu, C.-Y., Wang, C.-H., Lin, H.-C., Huang, C.-D., Huang, P.-Y., Fang, Y.-F., Shieh, M.-H., & Kuo, H.-P. (2004). The impact of delirium on the survival of mechanically ventilated patients*. Critical Care Medicine. https://doi.org/10.1097/01.ccm.0000145587.16421.bb
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