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Cited by 293

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

New-onset diabetes and antihypertensive drugs

Mancia, Giuseppe, Grassi, Guido, Zanchetti, Alberto·2006·Journal of Hypertension

Abstract

Observational studies have provided evidence that a consistent fraction (approximately 15-20%) of hypertensive patients displays a glucose intolerance state that may be aggravated by antihypertensive drug regimens based on thiazide diuretics or beta-blockers. This review examines the relative and absolute diabetogenic effects of antihypertensive drugs, by comparing the impact of 'new' (calcium antagonists, angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists) versus 'old' (diuretics and beta-blockers) drugs on new-onset diabetes in recent clinical trials. Evidence is provided that compared with diuretics and beta-blockers, new-onset diabetes is less common with 'new' drugs, and that conventional antihypertensive compounds, particularly when combined together, may amplify the natural time-dependent tendency towards the development of this metabolic disease. This paper provides new insights into the potential mechanisms responsible for the phenomenon and the clinical significance of antihypertensive drug-induced diabetes.

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Crossref · 10.1097/01.hjh.0000194119.42722.21

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Metadata

Authors
Mancia, G., Grassi, G., & Zanchetti, A.
Venue
Journal of Hypertension
Published
2006-01
Volume
24
Issue
1
Pages
3-10
ISSN
0263-6352 (ISSN-L)
OpenAlex
W2000747883
Cited by
293
References
11
FWCI
19.52
Type
journal article
Language
en
Open access
closed

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.