DIAGNOSTIC REFERENCE LEVELS FOR MEDICAL EXPOSURE OF PATIENTS: ICRP GUIDANCE AND RELATED ICRU QUANTITIES
Abstract
In Publication 60 of the International Commission on Radiological Protection reference levels were described as values of measured quantities at which some specified action or decision should be taken. One particular form of reference level, the diagnostic reference level, applies specifically to medical exposure of patients. The objective of a diagnostic reference level is to help avoid radiation dose to the patient that does not contribute to the clinical purpose of a medical imaging task. This is accomplished by comparison between the numerical value of the diagnostic reference level and the mean or other appropriate value observed in practice for a suitable reference group of patients or a suitable reference phantom. A diagnostic reference level is not applied to individual patients. Diagnostic reference levels have no direct linkage to the numerical values for dose limits or dose constraints, and it is inappropriate to use them for regulatory or commercial purposes. Diagnostic reference levels should be selected by professional medical bodies (often in conjunction with health and radiation protection authorities) and their values may be specific to a country or region. A diagnostic reference level can be used: (1) to improve a regional, national or local distribution of observed results for a general medical imaging task, by reducing the frequency of unjustified high or low values; (2) to promote attainment of a narrower range of values that represent good practice for a more specific medical imaging task; or (3) to promote attainment of an optimum range of values for a specified medical imaging protocol. Authorized bodies are encouraged to set diagnostic reference levels that best meet their specific needs and that are consistent for the regional, national or local area to which they apply. Report 74 of the International Commission on Radiation Units and Measurements includes a commentary regarding quantities useful in establishing diagnostic reference levels.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Numerous nations have established national diagnostic reference levels (DRLs) informed by demographic data, imaging methodologies, and equipment functionalities, adhering to guidelines from entities such as the ICRP and IAEA.
“Numerous nations have established national diagnostic reference levels (DRLs) informed by demographic data, imaging methodologies, and equipment functionalities, adhering to guidelines from entities such as the International Commission on Radiological Protection (ICRP) and the International Atomic Energy Agency (IAEA).4,5”
From Computed Tomography Diagnostic Reference Levels Worldwide and in Jordan: Implications for Patient Dose Reduction (2026) · cites this paper as [4]
Cited by
Sorted by citations
Smith‐Bindman, R., Wang, Y., Chu, P., Chung, R., Einstein, A. J., Balcombe, J. N., Cocker, M. R., Das, M., Delman, B. N., Flynn, M., et al. (2019) · BMJ · doi:10.1136/bmj.k4931 · Cited by 244 · see citing works
Radiation dose and protection in dentistry
Okano, T., & Sur, J. (2009) · Japanese Dental Science Review · doi:10.1016/j.jdsr.2009.11.004 · Cited by 108 · see citing works
“The objective of DRL is to control of medical radiation exposure to a level commensurate with the clinical purpose of a medical imaging task [73].”
BackgroundMiller, D. L., Hilohi, C. M., & Spelic, D. C. (2012) · Medical Physics · doi:10.1118/1.4754300 · Cited by 71 · see citing works
Bos, D., Yu, S., Luong, J., Chu, P., Wang, Y., Einstein, A. J., Starkey, J., Delman, B. N., Duong, P.-A. T., Das, M., et al. (2022) · European Radiology · doi:10.1007/s00330-021-08266-1 · Cited by 64 · see citing works
Paolicchi, F., Faggioni, L., Bastiani, L., Molinaro, S., Puglioli, M., Caramella, D., & Bartolozzi, C. (2014) · American Journal of Roentgenology · doi:10.2214/ajr.13.11741 · Cited by 40 · see citing works
Patient radiation dose audits for fluoroscopically guided interventional procedures
Balter, S., Rosenstein, M., Miller, D. L., et al. (2011) · Medical Physics · doi:10.1118/1.3557868 · Cited by 30 · see citing works
Self-citationBruijnen, S. T. G., Gent, Y. Y. J., Voskuyl, A. E., et al. (2013) · Arthritis Care & Research · doi:10.1002/acr.22184 · Cited by 27 · see citing works
“The use of radioisotopes can lead to an effective dose (47) of 7 mSv when 370 MBq of the tracer (18)F-FDG is used.”
BackgroundRacine, D., Ryckx, N., Ba, A. H., Becce, F., Viry, A., Verdun, F. R., & Schmidt, S. (2018) · European Radiology · doi:10.1007/s00330-018-5518-8 · Cited by 24 · see citing works
“(DRLs) allowed, to a certain extent, a reduction in the heterogeneity of the delivered dose exposure from one institution to another [5].”
BackgroundOsman, H., Raafat, B. M., Faizo, N. L., et al. (2021) · Applied Radiation and Isotopes · doi:10.1016/j.apradiso.2021.110049 · Cited by 19 · see citing works
Local Diagnostic Reference Levels for Typical Radiographic Procedures
Tonkopi, E., Daniels, C., Gale, M. J., et al. (2011) · Canadian Association of Radiologists Journal · doi:10.1016/j.carj.2011.02.004 · Cited by 19 · see citing works
“The diagnostic reference level (DRL), or reference values, represent an efficient criterion for radiation protection of patients and optimization of radiographic procedures [1].”
BackgroundDiagnostic radiology dosimetry: Status and trends
Rivera-Montalvo, T. (2016) · Applied Radiation and Isotopes · doi:10.1016/j.apradiso.2016.03.008 · Cited by 18 · see citing works
Tailoring CT Dose to Patient Size
Klosterkemper, Y., Appel, E., Thomas, C. K., et al. (2018) · Academic Radiology · doi:10.1016/j.acra.2018.03.005 · Cited by 15 · see citing works
Varghese, B., Kandanga, I., Puthussery, P., Vijayan, D., Babu, S. P. H., Aneesh, M. K., Noufal, M., Binu, E. V., Babu, A. C., James, S. M., et al. (2018) · Indian Journal of Radiology and Imaging · doi:10.4103/ijri.ijri_394_17 · Cited by 12 · see citing works
Implementation of Size-Dependent Local Diagnostic Reference Levels for CT Angiography
Boere, H., Eijsvoogel, N. G., Sailer, A. M., Wildberger, J. E., de Haan, M. W., Das, M., & Jeukens, C. R. L. P. N. (2018) · American Journal of Roentgenology · doi:10.2214/ajr.17.18566 · Cited by 11 · see citing works
A practical guide for paediatric diagnostic reference levels (PiDRLs)
Lackay, O., Horn-Lodewyk, J., & Muller, H. (2022) · Journal of medical imaging and radiation sciences · doi:10.1016/j.jmir.2021.12.005 · Cited by 10 · see citing works
Saukko, E., Henner, A., Nieminen, M. T., et al. (2016) · Radiation Protection Dosimetry · doi:10.1093/rpd/ncw018 · Cited by 10 · see citing works
Esmaeilyfard, R., Samanipour, A., & Paknahad, M. (2021) · Physica Medica · doi:10.1016/j.ejmp.2021.07.035 · Cited by 8 · see citing works
Radiation dosimetry in CT: the role of the manufacturer
Huda, W. (2011) · Imaging in Medicine · doi:10.2217/iim.11.12 · Cited by 8 · see citing works
Radiation doses from low-dose CT scans in SPECT/CT and PET/CT examinations: A survey in Germany
Rinscheid, A., Janzen, T., Alikhani, B., et al. (2022) · Nuklearmedizin - NuclearMedicine · doi:10.1055/a-1759-3900 · Cited by 6 · see citing works
Valores típicos de dosis para tomografía computada de cerebro en pacientes adultos
Andrea Serra, H., Cristián Ramírez, M., Javier Véliz, H., et al. (2020) · Revista de Fomento Social · doi:10.4067/s0717-93082020000100025 · Cited by 3 · see citing works
“El grupo total del estudio fue de 73 reportes dosimétricos, superando los requerimientos básicos estipulados por la ICRP(12) para determinar valores típicos de dosis en la modalidad de TC.”
BackgroundInfluentialMeasurements and applications of dose indices in radiography
Chen, T.-R., Tyan, Y., Yang, J., et al. (2011) · Radiation Measurements · doi:10.1016/j.radmeas.2011.07.001 · Cited by 2 · see citing works
Latifah, R., Rosyid, M. F., Yuana, F., et al. (2020) · Journal Of Vocational Health Studies · doi:10.20473/jvhs.v4.i2.2020.72-77 · Cited by 2 · see citing works
La dose in tomografia computerizzata
Faggioni, L., Paolicchi, F., & Neri, E. (2012) · Springer eBooks · doi:10.1007/978-88-470-2649-0_4 · Cited by 1 · see citing works
High-dose radioiodine outpatient therapy
Ward, L. S. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000300001 · Cited by 1 · see citing works
Oglat, A., Shdaifat, S., Sayah, M., Abukonna, A., & Khogali, W. (2026) · Drug, Healthcare and Patient Safety · doi:10.2147/dhps.s595721
Wu, S., Zhou, C., Xu, Y., et al. (2024) · Chinese Journal of Academic Radiology · doi:10.1007/s42058-024-00172-x
- Authors
- Rosenstein, M.
- Corresponding author
- Rosenstein, Marvin
- Venue
- Health Physics
- Published
- 2008-11
- Volume
- 95
- Issue
- 5
- Pages
- 528-534
- ISSN
- 0017-9078 (ISSN-L)
- OpenAlex
- W2036168363
- Cited by
- 26
- References
- 0
- Citations by year
- 2026: 1 · 2024: 1 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 4 · 2016: 2 · 2014: 1 · 2013: 1 · 2012: 2
- FWCI
- 1.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Health Physics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
- Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiology practices and education
- Keywords
- diagnostic reference levels, radiation dose, diagnostic imaging, radiation protection, reference phantom, dose optimization, radiation dose reduction
- MeSH terms
- Body Burden, Dose-Response Relationship, Radiation, Environmental Exposure, Humans, Nuclear Medicine, Radiation Dosage, Radiation Injuries, Radiation Monitoring, Radiation Protection, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Occupational Exposure, Risk Assessment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review