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Cited by 17Treatment of Major DepressionMental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Predictors of depression outcomes in medical inpatients with chronic pulmonary disease

Koenig, Harold G.·2006·The American Journal of Geriatric Psychiatry
DOI 10.1097/01.jgp.0000206380.57732.54
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Abstract

Objective Baseline patient characteristics and depression treatments were examined as predictors of speed of depression remission in hospitalized medical patients with chronic pulmonary disease (CPD).Methods Consecutively admitted patients over age 50 years with CPD were screened for major and minor depression using the Structured Clinical Interview for Depression. Patients with minor depression were followed up over 12-24 weeks with the Longitudinal Interview Follow-up Evaluation. Course of depression and predictors of remission were examined.Results Seven hundred eleven depressed patients with CPD (410 with minor, 301 with major depression) were identified and assessed over time. Two-thirds with minor depression had remitted by 12 weeks compared with 26.9% with major depression at 12 weeks and 49.2% at 24 weeks. Predictors of faster remission for minor depression were black race, community hospital admission, less severe depression, less medical comorbidity, less severe CPD, more social support, and no antidepressant treatment. For major depression, less severe depression, no past antidepressant drug treatment, and less intense current antidepressant treatment predicted faster remission.Conclusions The course of depressive disorder after discharge in patients hospitalized with CPD can be predicted by characteristics during admission. Although patients with minor depression may be followed and treatment initiated only if depression persists, those with major depression need more aggressive treatment and psychiatric consultation if improvement does not occur.

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  • Major depression in COPD is likely to require antidepressant medication or other specific mood-focused therapy to improve functioning and reduce the risk of chronic depression with its long-term adverse effects on overall disability.

    “By contrast, major depression is likely to require antidepressant medication or other specific mood-focused therapy79 to improve functioning and reduce the risk of chronic depression with its long-term adverse effects on overall disability.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [79]

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Authors
Koenig, H. G.
Affiliations
Duke University (US)
Corresponding author
Koenig, Harold G.
ORCID
Koenig, Harold G.
Venue
The American Journal of Geriatric Psychiatry
Publisher
Elsevier BV
Published
2006-11
Volume
14
Issue
11
Pages
939-948
ISSN
1064-7481 (ISSN-L)
DOI
10.1097/01.jgp.0000206380.57732.54
OpenAlex
W2044127019
Cited by
17
References
32
Citations by year
2017: 2 · 2016: 1 · 2015: 2 · 2012: 3
FWCI
1.25
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • American Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01mh057662-05)
  • National Institute of Mental Health (R01 MH 57662)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
depression, chronic lung disease, depression remission, predictors of remission, major depressive disorder, minor depression, medical inpatients, older adults, antidepressant treatment, social support, comorbidities, race, psychiatric consultation
MeSH terms
Adaptation, Psychological, Aged, Antidepressive Agents, Major Depressive Disorder, Depressive Disorder, Female, Follow-Up Studies, Humans, Life Change Events, Longitudinal Studies, Male, Middle Aged, Patient Admission, Remission, Spontaneous, Sick Role, Social Support, Outcome Assessment, Health Care, Pulmonary Disease, Chronic Obstructive

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