Randomized Trial of Therapeutic Massage for Chronic Neck Pain
Open accessAbstract
OBJECTIVES: Little is known about the effectiveness of therapeutic massage, one of the most popular complementary medical treatments for neck pain. A randomized controlled trial was conducted to evaluate whether therapeutic massage is more beneficial than a self-care book for patients with chronic neck pain. METHODS: Sixty-four such patients were randomized to receive up to 10 massages over 10 weeks or a self-care book. Follow-up telephone interviews after 4, 10, and 26 weeks assessed outcomes including dysfunction and symptoms. Log-binomial regression was used to assess whether there were differences in the percentages of participants with clinically meaningful improvements in dysfunction and symptoms (ie, >5-point improvement on the Neck Disability Index; >30% improvement from baseline on the symptom bothersomeness scale) at each time point. RESULTS: At 10 weeks, more participants randomized to massage experienced clinically significant improvement on the Neck Disability Index [39% vs. 14% of book group; relative risk (RR)=2.7; 95% confidence interval (CI), 0.99-7.5] and on the symptom bothersomeness scale (55% vs. 25% of book group; RR=2.2; 95% CI, 1.04-4.2). After 26 weeks, massage group members tended to be more likely to report improved function (RR=1.8; 95% CI, 0.97-3.5), but not symptom bothersomeness (RR=1.1; 95% CI, 0.6-2.0). Mean differences between groups were strongest at 4 weeks and not evident by 26 weeks. No serious adverse experiences were reported. CONCLUSIONS: This study suggests that massage is safe and may have clinical benefits for treating chronic neck pain at least in the short term. A larger trial is warranted to confirm these results.
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In another trial, intermediate-term effects of MT compared with standard care after 16 weeks of follow-up showed mean improvements of 4.7 versus 2.8.
“The other tested intermediate-term effects of MT were compared with standard care (mean improvements, 4.7 versus 2.8) after 16 weeks of follow-up [24].”
From Efficacy of Massage Therapy on Pain and Dysfunction in Patients with Neck Pain: A Systematic Review and Meta‐Analysis (2014) · cites this paper as [24]
The Methods (Outcome Measures; page unavailable) specify follow-up at 4, 10, and 26 weeks, not 16 weeks, and identify the comparison as a self-care book rather than standard care. The Results (Functional Status and Symptoms; page unavailable) report greater improvement with massage but do not give the claimed mean improvements of 4.7 versus 2.8. (LLM, conf=0.87)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredTwelve randomized controlled trials were eligible and included in the systematic review.
“Twelve high-quality studies were included.”
From Massage Therapy for Neck and Shoulder Pain: A Systematic Review and Meta-Analysis (2013) · cites this paper as [17]
The Study Design and Setting section describes this paper as a randomized trial, not a systematic review. The Discussion mentions a separate review of 19 trials, not 12 high-quality studies. No page numbers are available in our copy. (LLM, conf=0.88)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredFour studies reported favourable immediate effects of massage therapy on functional status compared with standard care, exercise (or standard care), and traction.
“Four of these studies reported favourable immediate effects compared with standard care [17], exercise (or standard care) [10], and traction [16, 19].”
From Massage Therapy for Neck and Shoulder Pain: A Systematic Review and Meta-Analysis (2013) · cites this paper as [17]
The Results, ‘Functional Status and Symptoms’ (page unavailable), report greater improvement in neck disability with massage at four weeks, supporting a favourable short-term effect on functional status. But the Methods, ‘Treatments’ (page unavailable), identify the comparator as a self-care book containing exercise recommendations and information on conventional treatment—not an exercise or standard-care treatment arm. This paper therefore does not support that comparator description for its study. (LLM, conf=0.87)
Experimental — accuracy not yet measuredTwo randomized controlled trials were excluded from the meta-analyses because of unsuitable main outcomes.
“Two RCTs were excluded from meta-analyses due to unsuitable main outcomes [15, 17].”
From Massage Therapy for Neck and Shoulder Pain: A Systematic Review and Meta-Analysis (2013) · cites this paper as [17]
The Materials and Methods (Outcome Measures; page unavailable) confirm that this paper is a randomized trial and identify its primary outcomes as neck-related disability and symptom bothersomeness. The paper does not say that it or another trial was excluded from the citing authors’ meta-analyses, or that its outcomes were unsuitable for them. (LLM, conf=0.81)
Experimental — accuracy not yet measuredIn one randomized controlled trial, massage therapy for chronic neck pain produced clinically significant improvements compared with standard care on the neck disability index (39% versus 14%) and symptom bothersomeness scale (55% versus 25%).
“The other RCT [17] assessed the effectiveness of MT for chronic neck pain compared with standard care. The author found that participants in the massage group experienced clinically significant improvements on neck disability index (39% versus 14% of standard care group) and on the symptom bothersomeness scale (55% versus 25% of standard care group).”
From Massage Therapy for Neck and Shoulder Pain: A Systematic Review and Meta-Analysis (2013) · cites this paper as [17]
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Another trial reported that 9 (about 28%) participants had mild adverse experiences including discomfort, pain, soreness, and nausea.
“The other trial reported that 9 (about 28%) participants had mild adverse experiences including discomfort, pain, soreness, and nausea [24].”
From Efficacy of Massage Therapy on Pain and Dysfunction in Patients with Neck Pain: A Systematic Review and Meta‐Analysis (2014) · cites this paper as [24]
A suspected reason for the difference from Ezzo et al. is that six high-quality randomized controlled trials have been published since 2003, of which five favored massage therapy.
“One suspected reason for this difference is that 6 high-quality RCTs [13–17, 19] have been published since 2003, of which 5 favored MT.”
From Massage Therapy for Neck and Shoulder Pain: A Systematic Review and Meta-Analysis (2013) · cites this paper as [17]
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- Authors
- Sherman, K. J., Cherkin, D. C., Hawkes, R. J., Miglioretti, D. L., & Deyo, R. A.
- Affiliations
- Group Health Cooperative (US)
- University of Washington (US)
- Corresponding author
- Sherman, Karen J.
- Cherkin, Daniel C.
- Hawkes, Rene J.
- Miglioretti, Diana L.
- Venue
- The Clinical Journal of Pain
- Published
- 2009-03
- Volume
- 25
- Issue
- 3
- Pages
- 233-238
- ISSN
- 0749-8047 (ISSN-L)
- PMC
- PMC2664516
- OpenAlex
- W2134651956
- Cited by
- 126
- References
- 29
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 8 · 2023: 7 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 8 · 2018: 4 · 2017: 4 · 2016: 9 · 2015: 12 · 2014: 12 · 2013: 10 · 2012: 16
- FWCI
- 7.43
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Journal of Pain (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Center for Complementary and Alternative Medicine
- National Center for Complementary and Integrative Health (R21AT001584)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Keywords
- therapeutic massage, chronic neck pain, complementary therapy, Neck Disability Index, neck dysfunction, treatment effectiveness
- MeSH terms
- Adult, Chronic Disease, Disability Evaluation, Female, Follow-Up Studies, Humans, Massage, Middle Aged, Pain Measurement, Retrospective Studies, Self Care, Time Factors, Treatment Outcome, Outcome Assessment, Health Care, Neck Pain, Young Adult
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