Expanding our horizons: transition of acute postoperative pain to persistent pain and establishment of chronic postsurgical pain services

Persistent postsurgical pain: risk factors and prevention

Kehlet, H., Jensen, T. S., & Woolf, C. J. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68700-x · Cited by 4,086 · see citing works

Postoperative Pain Experience: Results from a National Survey Suggest Postoperative Pain Continues to Be Undermanaged

Apfelbaum, J. L., Chen, C., Mehta, S. S., & Gan, A. T. J. (2003) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000068822.10113.9e · Cited by 2,207 · see citing works

Opioid-induced Hyperalgesia: A Qualitative Systematic Review

Angst, M. S., & Clark, J. D. (2006) · Anesthesiology · doi:10.1097/00000542-200603000-00025 · Cited by 1,188 · see citing works

Prediction of chronic post-operative pain: Pre-operative DNIC testing identifies patients at risk

Yarnitsky, D., Crispel, Y., Eisenberg, E., Granovsky, Y., Ben-Nun, A., Sprecher, E., Best, L.-A., & Granot, M. (2008) · Pain · doi:10.1016/j.pain.2007.10.033 · Cited by 750 · see citing works

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

Tegeder, I., Costigan, M., Griffin, R. S., Abele, A., Belfer, I., Schmidt, H., Ehnert, C., Nejim, J. A., Marian, C., Scholz, J., et al. (2006) · Nature Medicine · doi:10.1038/nm1490 · Cited by 548 · see citing works

Intraoperative Epidural Analgesia Combined with Ketamine Provides Effective Preventive Analgesia in Patients Undergoing Major Digestive Surgery

Lavand'homme, P. M., Kock, M. D., & Waterloos, H. (2005) · Anesthesiology · doi:10.1097/00000542-200510000-00020 · Cited by 354 · see citing works

Cut and thrust: antecedent surgery and trauma among patients attending a chronic pain clinic

Crombie, I. K., Davies, H. T. O., & Macrae, W. A. (1998) · Pain · doi:10.1016/s0304-3959(98)00038-4 · Cited by 351 · see citing works

General anesthetics activate a nociceptive ion channel to enhance pain and inflammation

Matta, J. A., Cornett, P. M., Miyares, R. L., Abe, K., Sahibzada, N., & Ahern, G. P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711038105 · Cited by 265 · see citing works

Postcesarean Section Pain Prediction by Preoperative Experimental Pain Assessment

Granot, M., Löwenstein, L., Yarnitsky, D., Tamir, A., & Zimmer, E. Z. (2003) · Anesthesiology · doi:10.1097/00000542-200306000-00018 · Cited by 248 · see citing works

Perceived intensity and unpleasantness of cutaneous and auditory stimuli: An evaluation of the generalized hypervigilance hypothesis

Hollins, M., Harper, D., Gallagher, S., Owings, E. W., Lim, P. F., Miller, V. E., Siddiqi, M., & Maixner, W. D. (2009) · Pain · doi:10.1016/j.pain.2008.10.003 · Cited by 165 · see citing works

Postoperative pain after hip fracture is procedure specific

Foss, N. B., Kristensen, M. T., Palm, H., & Kehlet, H. (2008) · British Journal of Anaesthesia · doi:10.1093/bja/aen345 · Cited by 100 · see citing works

Preventing Chronic Pain After Surgery: Who, How, and When?

Eisenach, J. C. (2006) · Regional Anesthesia & Pain Medicine · doi:10.1016/j.rapm.2005.11.008 · Cited by 92 · see citing works

Trauma and fibromyalgia: Is there an association and what does it mean?

White, K. P., Carette, S., Harth, M., & Teasell, R. W. (2000) · Seminars in Arthritis and Rheumatism · doi:10.1016/s0049-0172(00)80009-8 · Cited by 62 · see citing works

Does the Pain-Protective GTP Cyclohydrolase Haplotype Significantly Alter the Pattern or Severity of Pain in Humans with Chronic Pancreatitis?

Lazarev, M. G., Lamb, J., Barmada, M. M., Dai, F., Anderson, M. A., Max, M. B., & Whitcomb, D. C. (2008) · Molecular Pain · doi:10.1186/1744-8069-4-58 · Cited by 40 · see citing works

Maternal family history of hypertension attenuates neonatal pain response

France, C. R., Taddio, A., Shah, V. S., Pagé, M. G., & Katz, J. D. (2009) · Pain · doi:10.1016/j.pain.2008.12.010 · Cited by 33 · see citing works

Transition from acute to chronic pain after surgery

Glare, P., Aubrey, K. R., & Myles, P. S. (2019) · The Lancet · doi:10.1016/s0140-6736(19)30352-6 · Cited by 914 · see citing works

When does acute pain become chronic?

Voscopoulos, C., & Lema, M. (2010) · British Journal of Anaesthesia · doi:10.1093/bja/aeq323 · Cited by 473 · see citing works

The progression from acute to chronic pain

Lavand’homme, P. (2011) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0b013e32834a4f74 · Cited by 179 · see citing works

Chronification of Pain: Mechanisms, Current Understanding, and Clinical Implications

Pak, D., Yong, R. J., Kaye, A. D., & Urman, R. D. (2018) · Current Pain and Headache Reports · doi:10.1007/s11916-018-0666-8 · Cited by 172 · see citing works

Transition from acute to chronic pain after surgery

Lavand'homme, P. M. (2017) · Pain · doi:10.1097/j.pain.0000000000000809 · Cited by 159 · see citing works

Prevalence and risk factors for chronic pain following cesarean section: a prospective study

Jin, J., Peng, L., Chen, Q., Zhang, D., Ren, L., Qin, P., & Min, S. (2016) · BMC Anesthesiology · doi:10.1186/s12871-016-0270-6 · Cited by 155 · see citing works

Predictors of Postoperative Pain Trajectories in Adolescent Idiopathic Scoliosis

Connelly, M. A., Fulmer, R. D., Prohaska, J., Anson, L. M., Dryer, L., Thomas, V., Ariagno, J., Price, N., & Schwend, R. M. (2013) · Spine · doi:10.1097/brs.0000000000000099 · Cited by 145 · see citing works

Prevention of chronic postoperative pain: Cellular, molecular, and clinical insights for mechanism-based treatment approaches

Deumens, R., Steyaert, A., Forget, P., Schubert, M., Lavand'homme, P. M., Hermans, E., & Kock, M. D. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.01.002 · Cited by 123 · see citing works

Handbook of Pain and Palliative Care

Moore, R. J. (2012) · Springer eBooks · doi:10.1007/978-1-4419-1651-8 · Cited by 116 · see citing works

The transition from acute to chronic post surgical pain

Shipton, E. A. (2011) · Anaesthesia and Intensive Care · doi:10.1177/0310057x1103900506 · Cited by 108 · see citing works

Regional Techniques for Cardiac and Cardiac-Related Procedures

Mittnacht, A. J. C., Shariat, A. N., Weiner, M. M., Malhotra, A., Miller, M. A., Mahajan, A., & Bhatt, H. V. (2018) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2018.09.017 · Cited by 108 · see citing works

Prevention and Treatment of Chronic Postsurgical Pain: A Narrative Review

Steyaert, A., & Lavand’homme, P. (2018) · Drugs · doi:10.1007/s40265-018-0866-x · Cited by 97 · see citing works

A Double-blind Randomized Trial of Wound and Intercostal Space Infiltration with Ropivacaine during Breast Cancer Surgery: Effects on Chronic Postoperative Pain

Albi-Feldzer, A., Mouret-Fourme E, E., Hamouda, S., Motamed, C., Dubois, P.-Y., Jouanneau, L., & Jayr, C. (2013) · Anesthesiology · doi:10.1097/aln.0b013e31827d88d8 · Cited by 90 · see citing works

“It's there and I'm stuck with it”: Patients' experiences of chronic pain following total knee replacement surgery

Jeffery, A. E., Wylde, V., Blom, A. W., & Horwood, J. P. (2010) · Arthritis Care & Research · doi:10.1002/acr.20360 · Cited by 81 · see citing works

Preemptive and Preventive Pain Psychoeducation and Its Potential Application as a Multimodal Perioperative Pain Control Option: A Systematic Review

Horn, A., Kaneshiro, K., & Tsui, B. C. H. (2019) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000004319 · Cited by 79 · see citing works

New approach for treatment of prolonged postoperative pain: APS Out-Patient Clinic

Tiippana, E., Hamunen, K., Heiskanen, T., Nieminen, T., Kalso, E., & Kontinen, V. K. (2016) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2016.02.008 · Cited by 76 · see citing works

Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial

Paul, J., Nantha-Aree, M., Buckley, N., Cheng, J., Thabane, L., Tidy, A., DeBeer, J., Winemaker, M., Wismer, D., Punthakee, D., et al. (2013) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-013-9902-1 · Cited by 72 · see citing works

Different protocols used today to achieve total opioid-free general anesthesia without locoregional blocks

Mauermann, E., Ruppen, W., & Bandschapp, O. (2017) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2017.11.003 · Cited by 63 · see citing works

Can anaesthetic technique effect postoperative outcome?

Kavanagh, T., & Buggy, D. J. (2012) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0b013e32834f6c4c · Cited by 62 · see citing works

Hypnosis in the Perioperative Management of Breast Cancer Surgery: Clinical Benefits and Potential Implications

Potié, A., Roelants, F., Pospiech, A., Momeni, M., & Watremez, C. (2016) · Anesthesiology Research and Practice · doi:10.1155/2016/2942416 · Cited by 47 · see citing works

Prevention of chronic post-surgical pain: the importance of early identification of risk factors

Tawfic, Q. A., Kumar, K., Pirani, Z., & Armstrong, K. (2017) · Journal of Anesthesia · doi:10.1007/s00540-017-2339-x · Cited by 44 · see citing works

Thirty-five Years of Acute Pain Services: Where Do We Go From Here?

Stamer, U. M., Liguori, G. A., & Rawal, N. (2020) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000004655 · Cited by 43 · see citing works

Integration of computer simulation in design for manufacturing and assembly

da Silva, C. E. S., Salgado, E. G., Mello, C. H. P., Oliveira, E., & Leal, F. (2013) · International Journal of Production Research · doi:10.1080/00207543.2013.853887 · Cited by 40 · see citing works

Chronic pain after vaginal and cesarean delivery: a reality questioning our daily practice of obstetric anesthesia

Lavand'homme, P. M. (2009) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2009.09.003 · Cited by 39 · see citing works

Ultrasound-guided bilateral rectus sheath block reduces early postoperative pain after laparoscopic gynecologic surgery: a randomized study

Cho, S., Kim, Y. J., Jeong, K., & Moon, H. S. (2018) · Journal of Anesthesia · doi:10.1007/s00540-018-2457-0 · Cited by 38 · see citing works

A prospective study of chronic postsurgical pain in elderly patients: incidence, characteristics and risk factors

Jin, J., Zhang, T., Xiong, X., Chen, H., Jiang, Y., & He, S. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-04006-w · Cited by 34 · see citing works

Acute Pain Service: Past, Present and Future

Tawfic, Q. A., & Faris, A. S. (2015) · Pain Management · doi:10.2217/pmt.14.48 · Cited by 29 · see citing works

Independent Verification and Validation of an Industrial Simulation Model

Robinson, S., & Brooks, R. J. (2009) · SIMULATION · doi:10.1177/0037549709341582 · Cited by 28 · see citing works

Management of postoperative pain in Spain: a nationwide survey of practice

Montes, A., Aguilar, J. L., Benito, M. C., Caba, F., Margarit, C., & Acute Pain Group of the Spanish Pain Society (SED) (2017) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.12876 · Cited by 25 · see citing works

Chronic postsurgical pain: still a neglected topic?

Kissin, I., & Gelman (2012) · Journal of Pain Research · doi:10.2147/jpr.s35145 · Cited by 24 · see citing works

Postoperative opioids

Steyaert, A., & Lavand'homme, P. M. (2013) · European Journal of Anaesthesiology · doi:10.1097/eja.0b013e32835b9db2 · Cited by 23 · see citing works

Protein Kinase C γ Interneurons Mediate C-fiber–induced Orofacial Secondary Static Mechanical Allodynia, but Not C-fiber–induced Nociceptive Behavior

Peirs, C., Bourgois, N., Artola, A., & Dallel, R. (2016) · Anesthesiology · doi:10.1097/aln.0000000000001000 · Cited by 23 · see citing works

Postoperative pain management

Park, Y., & Woo, Y. C. (2015) · Journal of Korean Medical Association · doi:10.5124/jkma.2015.58.11.1011 · Cited by 22 · see citing works

Pre- and post-operative psychological interventions to prevent pain and fatigue after breast cancer surgery (PREVENT): Protocol for a randomized controlled trial

Reme, S. E., Munk, A., Holter, M. T. S., Falk, R. S., & Jacobsen, H. B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0268606 · Cited by 21 · see citing works

Alien at home: Adjustment strategies of students returning from a six-months over-sea's educational programme

Dettweiler, U., Ünlü, A., Lauterbach, G., Legl, A., Simon, P. D., & Kugelmann, C. (2014) · International Journal of Intercultural Relations · doi:10.1016/j.ijintrel.2014.10.005 · Cited by 21 · see citing works

Chronic postoperative pain and sensory changes following reduction mammaplasty

von Sperling, M. L., Høimyr, H., Finnerup, K., Jensen, T. S., & Finnerup, N. B. (2011) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2011.01.002 · Cited by 17 · see citing works

The Registry Imperative

Hannenberg, A. A., & Warner, M. A. A. (2009) · Anesthesiology · doi:10.1097/aln.0b013e3181b786f3 · Cited by 16 · see citing works

Acute and chronic neuropathic pain after surgery

Steyaert, A., & Lavand'homme, P. M. (2017) · European Journal of Anaesthesiology · doi:10.1097/eja.0000000000000682 · Cited by 13 · see citing works

Pain therapy to reduce perioperative complications

Freys, S. M., & Pogatzki-Zahn, E. M. (2019) · Innovative Surgical Sciences · doi:10.1515/iss-2019-0008 · Cited by 12 · see citing works

Perioperative Comparative Effectiveness Research

Kheterpal, S. (2009) · Anesthesiology · doi:10.1097/aln.0b013e3181bfabb4 · Cited by 12 · see citing works

The incidence of persistent postoperative opioid use among U.S. veterans: A national study to identify risk factors

Namiranian, K., Siglin, J., & Sorkin, J. D. (2020) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2020.110079 · Cited by 11 · see citing works

Efficacy of Intrathoracic Intercostal Nerve Block on Postoperative Acute and Chronic Pains of Patients Undergoing Video-Assisted Thoracoscopic Surgery

Zhao, X., Li, X., Wang, Y., Xiao, W., Zhang, B., Meng, X., & Sun, X. (2022) · Journal of Pain Research · doi:10.2147/jpr.s369042 · Cited by 10 · see citing works

The effects of different analgesic methods on chronic pain in patients undergoing video-assisted thoracoscopic surgery.

Zhao, X., Xiao, W., Zhang, T., Xi, M., & Sun, X. (2022) · Videosurgery and Other Miniinvasive Techniques · doi:10.5114/wiitm.2022.120572 · Cited by 8 · see citing works

Schmerz und Anästhesiologie

Witte, W. (2011) · Der Anaesthesist · doi:10.1007/s00101-011-1874-3 · Cited by 8 · see citing works

The long‐term incidence of chronic post‐surgical pain after coronary artery bypass surgery – A prospective observational study

Charlton, E. J., Atkins, K. J., Evered, L. A., SILBERT, B. S., & Scott, D. A. (2023) · European Journal of Pain · doi:10.1002/ejp.2203 · Cited by 7 · see citing works

Douleurs chroniques après chirurgie : état des lieux

Lavand'homme, P. M. (2015) · La Presse Médicale · doi:10.1016/j.lpm.2014.09.025 · Cited by 7 · see citing works

Association between aesthetic satisfaction and chronic postsurgical pain in breast cancer patients treated with one stage prosthesis implantation

Wang, B., Gao, P., Wang, J., & Zheng, H. (2022) · Scientific Reports · doi:10.1038/s41598-022-05185-z · Cited by 7 · see citing works

A History of Regional Anesthesia

Mulroy, M. F. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8441-7_63 · Cited by 6 · see citing works

Pain after Surgery—Acute Becomes Chronic: Might There be a Silver Rocket?

Schug, S. A. (2017) · Anaesthesia and Intensive Care · doi:10.1177/0310057x1704500404 · Cited by 5 · see citing works

Current Approaches to Four Challenging Pain Syndromes

Μoka, Ε., Allam, A. E.-S., Rekatsina, M., Abed, L. A., Paladini, A., AlKharabsheh, A., Vadalouca, A., & Varrassi, G. (2023) · Cureus · doi:10.7759/cureus.45573 · Cited by 4 · see citing works

Opioid-induced hyperalgesia: New insights into the chronicization of pain

Veevaete, L., & Lavand'homme, P. M. (2014) · Techniques in Regional Anesthesia and Pain Management · doi:10.1053/j.trap.2015.10.004 · Cited by 4 · see citing works

Acute to Chronic Pain: Transition in the Post-Surgical Patient

Short, R. T., & Vetter, T. R. (2011) · Springer eBooks · doi:10.1007/978-1-4419-1651-8_19 · Cited by 3 · see citing works

Situación actual del dolor postoperatorio en el “Año Global Contra el Dolor Agudo”

Pérez, A. M., Alvarez, J., & Trillo, L. (2011) · Revista Española de Anestesiología y Reanimación · doi:10.1016/s0034-9356(11)70060-3 · Cited by 3 · see citing works

Calidad de atención del dolor postoperatorio en cirugía ginecológica

Calderón-Estrada, M., Pichardo-Cuevas, M., Suárez-Muñiz, M. P. B., Ramírez–Montiel, M. L., & Contreras-Carreto, N. A. (2012) · Médica Sur · Cited by 2 · see citing works

Erhebung von Schmerzen nach ambulanten Operationen

Schwarze, C., Zenz, D., Orlowski, O., Wempe, C., Aken, H. V., Zahn, P. K., Maier, C., & Pogatzki-Zahn, E. M. (2015) · Der Schmerz · doi:10.1007/s00482-015-0071-8 · Cited by 2 · see citing works

Engaging men in ending men’s violence against women

Flood, M. (2018) · Routledge eBooks · doi:10.4324/9780429423468-9 · Cited by 2 · see citing works

Perioperative Methadone in Orthopedic Surgery: A Scoping Review

Yang, A., Lee, E., Babaei, M., & Lee, P. S. (2025) · Healthcare · doi:10.3390/healthcare13192431 · Cited by 1 · see citing works

Postoperative acute pain

Cata, J. P., & Zaky, S. S. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9780511793851.021 · Cited by 1 · see citing works

Methadone Prescribing in the Sickle Cell Patient

Smith, W., & Alsalman, A. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6974-2_18 · Cited by 1 · see citing works

Pain in the Battlefield Injured

Dragovich, A., & Cohen, S. P. (2011) · Springer eBooks · doi:10.1007/978-1-4419-1651-8_14

Postoperative care of the adult patient

Farag, E. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9780511793851.018

Taking a systems neuroscience approach to persistent postsurgical pain : mechanisms, prediction tools and preventive strategies

Anwar, S. (2016) · Queen Mary Research Online (Queen Mary University of London)

Pain Management on the Battlefield

Liu, R., Reid, C. O., & Cohen, S. P. (2018) · Springer eBooks · doi:10.1007/978-3-319-95369-4_13

Використання габапентину для премедікації при хірургічних втручаннях в онкоурології

Климчук, Л. В., Лісний, І. І., Стаховський, Е. О., Галак, І. І., Наумчук, Г. В., & Бєлка, К. Ю. (2012) · doi:10.25284/2519-2078.3(60).2012.107339

Acute to Chronic Pain: Transition in the Postsurgical Patient

Garman, J., Paul, C., & Short, R. T. (2018) · Springer eBooks · doi:10.1007/978-3-319-95369-4_16

Craniotomy

Grasu, R. M., & Raty, S. R. (2019) · Oxford University Press eBooks · doi:10.1093/med/9780190856649.003.0016

Spinal Deformity Surgery

Ferreira, R. J. R., Bordini, E. C., dos Santos, A. C. J., Pontes, R. W. F., Cavali, P. T. M., & Gonzaga, T. B. (2022) · Springer eBooks · doi:10.1007/978-3-030-95730-8_22

Gestion de l’analgésie à domicile dans le cadre de la réhabilitation améliorée après chirurgie

Evans, I., Aubrun, F., & Theissen, A. (2022) · Douleur et Analgésie · doi:10.3166/dea-2022-0236

Connecting assessment and strategic planning to advancing equity on campus

Clark, J., & Brown, S. S. (2017) · Journal of Student Affairs Inquiry Improvement and Impact · doi:10.18060/27879

Chirurgische Therapie von Wirbelsäulendeformitäten

Ferreira, R. J. R., Bordini, E. C., dos Santos, A. C. J., Pontes, R. W. F., Cavali, P. T. M., & Gonzaga, T. B. (2025) · Springer eBooks · doi:10.1007/978-3-031-72258-5_22

Acute Pain Management Services

Choudhary, N., & Magoon, R. (2025) · Springer eBooks · doi:10.1007/978-981-96-7822-8_8

Recommendations for perioperative pain medicine focusing on structures, processes, and organisation

Rehberg, B., Schneider, T., & Stamer, U. M. (2026) · Swiss Medical Weekly · doi:10.57187/4797

Chronic Postsurgical Pain: Identification and Management

Feldheim, T. V., & Tighe, P. (2026) · Springer eBooks · doi:10.1007/978-3-032-11484-6_20

Long-term Consequences of Anesthetic Management

Sessler, D. I. (2009) · Anesthesiology · doi:10.1097/aln.0b013e3181a913e1 · Cited by 124 · see citing works

Anesthesia, Surgery and Long-Term Outcomes

Stoelting, R. K. (2005) · ASA Monitor

Implications of Postoperative Infections on Long-term Outcomes

Chen, Z., Han, E. Y., & Ling, X. L. (2020) · JAMA Surgery · doi:10.1001/jamasurg.2020.0418 · Cited by 1 · see citing works

ANNOUNCEMENT AND CALL FOR Meeting Abstracts

(2010) · Anesthesiology · doi:10.1097/01.anes.0000368883.25930.bb

Implications of Postoperative Infections on Long-term Outcomes—Reply

O’Brien, W. J., Gupta, K., & Itani, K. M. F. (2020) · JAMA Surgery · doi:10.1001/jamasurg.2020.0419