Quality of life and sexual function 2 years after vaginal surgery for prolapse.
Open accessAbstract
OBJECTIVE: To longitudinally assess the effect of native tissue vaginal apical prolapse repair with anti-incontinence surgery on quality of life, sexual function, and body image between uterosacral and sacrospinous suspensions. METHODS: A planned secondary analysis was performed on 374 women enrolled in a randomized trial of the two types of native tissue repair for apical prolapse. Condition-specific and generic quality of life, sexual function, overall and de novo dyspareunia, and body image were assessed using validated instruments at baseline; 6, 12, and 24 months postoperatively; and changes from baseline were assessed and compared between surgical groups. General linear mixed models were used for comparisons and clinically significant differences were assessed using minimum important differences. RESULTS: Of the women randomized, 82% had outcomes available at 2 years. Overall, clinically and statistically significant improvements in generic and condition-specific quality of life and sexual function were observed after surgery. Dyspareunia rates decreased from 25% to 16% by 24 months with only 3% of all women undergoing treatment. De novo dyspareunia occurred in 5% and 10% by 12 and 24 months, respectively. Body image scores also significantly improved from baseline. There were no clinically meaningful or statistically significant differences between groups for any of these outcomes (all P>.05). CONCLUSION: Native tissue vaginal prolapse surgery results in statistically and clinically significant improvements in quality of life, sexual function, and body image at 24 months with no significant differences between uterosacral and sacrospinous suspensions. One in 10 women experience de novo dyspareunia but few requested treatment. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00597935.
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A conservative estimate of the minimal clinically important difference for the POPDI has been previously reported to be 34.3 points.
“A conservative estimate of the minimal clinically important difference for the POPDI has been previously reported to be 34.3 points.18,19”
From Standard Restrictions vs Expedited Activity After Pelvic Organ Prolapse Surgery (2023) · cites this paper as [19]
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Brandon, C. A., Friedman, S., Rosenblum, N., Escobar, C. M., Stewart, L. E., & Brucker, B. M. (2022) · International Urogynecology Journal · doi:10.1007/s00192-022-05372-6 · Cited by 1 · see citing works
Obesity and Native Tissue Repairs: A Secondary Analysis of the OPTIMAL Trial
Hagedorn, M. K., Locklear, T. M., Evans, S., Karp, N. E., & Greer, W. J. (2024) · Urogynecology · doi:10.1097/spv.0000000000001498 · Cited by 1 · see citing works
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Female Sexuality in Pelvic Floor Disorders
Halder, G. E., White, A. B., & Rogers, R. G. (2021) · Urodynamics, neurourology and pelvic floor dysfunctions · doi:10.1007/978-3-030-57393-5_15 · Cited by 1 · see citing works
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SACROSPINOUS LIGAMENT FIXATION FOR APICAL PROLAPSE REPAIR COMPARED TO OTHER VAGINAL PROCEDURES
Ionescu, O., Bacalbaşa, N., Saba, N., & Banceanu, G. (2017) · Romanian Journal of Medical Practice · doi:10.37897/rjmp.2017.4.6
Quality of Life and Sexual Function 2 Years After Vaginal Surgery for Prolapse: Correction
(2017) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000001893
Pelvic floor dysfunction in women after hysterectomy
Vermeulen, C. K. M. (2024) · doi:10.26481/dis.20241204cv
Robotic/Laparoscopic Female Pelvic Reconstructive Surgery
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Improvement of Pelvic Pain Associated with Pelvic Organ Prolapse After Reconstructive SurgeryPreprint
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Strategies to improve sexual health in women with urinary incontinence: A scoping review
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Sexual Function After Prolapse Repair and Retropubic Versus Single-incision Sling
Choi, J. Y., Gutman, R. E., Iglesia, C. B., Russell, G., Rardin, C., Kenton, K. A., & Matthews, C. A. (2026) · Urogynecology · doi:10.1097/spv.0000000000001888
Sexual function after urogynecologic surgery
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- Authors
- Lukacz, E. S., Warren, L. K., Richter, H. E., Brubaker, L., Barber, M. D., Norton, P., Weidner, A. C., Nguyen, J. N., & Gantz, M. G.
- Affiliations
- Cleveland Clinic (US)
- ORCID
- Venue
- Obstetrics & Gynecology
- Published
- 2016-06
- Volume
- 127
- Issue
- 6
- Pages
- 1071-1079
- ISSN
- 0029-7844 (ISSN-L)
- PMC
- PMC4879084
- OpenAlex
- W2372075305
- Cited by
- 72
- References
- 29
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 10 · 2020: 8 · 2019: 9 · 2018: 9 · 2017: 9 · 2016: 1
- FWCI
- 9.93
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10HD041261, U10HD054136, UG1HD041261, U10HD054214, U01HD041249, U10HD054215, UG1HD054215, U01HD069031, U10HD041267, U10HD054241, U10HD041250, UG1HD054214)
- Topics
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
- Keywords
- quality of life, sexual function, dyspareunia, body image, anti-incontinence surgery, long-term outcomes
- MeSH terms
- Body Image, Female, Humans, Middle Aged, Postoperative Period, Quality of Life, Surveys and Questionnaires, Sexual Behavior, Urinary Incontinence, Uterine Prolapse, Suburethral Slings
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