Particulate Air Pollution Exposure and C-reactive Protein During Early Pregnancy
Open accessAbstract
BACKGROUND: It is not well understood how air pollution leads to adverse pregnancy outcomes. One pathway may be through C-reactive protein, a biomarker of systemic inflammation that has been reported to increase the risk of preterm delivery. We examined whether air pollution influences serum concentrations of C-reactive protein in early pregnancy. METHODS: We studied 1696 pregnant women in Allegheny County, PA, from 1997 through 2001. C-reactive protein concentrations were assayed in blood collected before the 22nd week of gestation. We estimated levels of particles of less than 10 μm (PM10) and less than 2.5 μm diameter (PM2.5), carbon monoxide, nitrogen dioxide, sulfur dioxide, and ozone at the maternal zip code using Kriging interpolation for measurements obtained from ambient stations. Associations between air pollution and high C-reactive protein concentrations (≥ 8 ng/mL) were evaluated using logistic regression. RESULTS: Among nonsmokers, an observed 9.2 μg/m increase in PM10 (averaged over 28 days prior to the blood sample) was associated with an odds ratios of 1.41 for high C-reactive protein concentrations (95% confidence interval = 0.99-2.00). Similarly, a 4.6 μg/m increase in PM2.5 was associated with an odds ratio of 1.47 (1.05-2.06). The odds ratio was 1.49 (0.75-2.96) per 7.9 ppb increase in ozone during summer. There were no associations in smokers or for other air pollutants, and there was no evidence for effect-measure modification by obesity. CONCLUSIONS: PM10, PM2.5, and ozone exposures were associated with increased C-reactive protein concentrations in early pregnancy, suggesting that these air pollutants contribute to inflammation and thereby possibly to adverse pregnancy outcomes.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
PM2.5 exposure was associated with increased C-reactive protein (CRP) concentrations in early pregnancy.
“Investigators observed PM2.5 exposure was associated with increased C-reactive protein (CRP) concentrations in early pregnancy [165].”
From Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter (2021) · cites this paper as [165]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
THE IMPACT OF CONFOUNDER SELECTION CRITERIA ON EFFECT ESTIMATION
Mickey, R. M., & Greenland, S. (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115101 · Cited by 2,382 · see citing works
RE:“;THE IMPACT OF CONFOUNDER SELECTION CRITERIA ON EFFECT ESTIMATION”
Greenland, S., & Mickey, R. M. (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115409 · Cited by 2,114 · see citing works
Oxidative stress-induced DNA damage by particulate air pollution
Risom, L., Möller, P., & Loft, S. H. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2005.06.012 · Cited by 914 · see citing works
Ambient Particle Inhalation and the Cardiovascular System: Potential Mechanisms
Donaldson, K., Stone, V., Seaton, A., & MacNee, W. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.01109s4523 · Cited by 690 · see citing works
Kannan, S., Misra, D. P., Dvonch, J. T., & Krishnakumar, A. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9081 · Cited by 505 · see citing works
Ambient Air Pollution and Risk of Birth Defects in Southern California
Ritz, B. R. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.1.17 · Cited by 463 · see citing works
Self-citationDubowsky, S. D., Suh, H. H., Schwartz, J. D., Coull, B. A., & Gold, D. R. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8469 · Cited by 431 · see citing works
Ambient Air Pollution and Low Birth Weight in Connecticut and Massachusetts
Bell, M. L., Ebisu, K., & Belanger, K. D. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.9759 · Cited by 422 · see citing works
Particulate air pollution and the blood
Seaton, A., Soutar, A., Crawford, V., Elton, R., McNerlan, S., Cherrie, J., Watt, M., Agius, R., & Stout, R. (1999) · Thorax · doi:10.1136/thx.54.11.1027 · Cited by 409 · see citing works
Air Pollution and Markers of Inflammation and Coagulation in Patients with Coronary Heart Disease
Rückerl, R., Ibald-Mulli, A., Köenig, W., Schneider, A. E., Wölke, G., Cyrys, J., Heinrich, J., Marder, V. J., Frampton, M. W., Wichmann, H. ‐., et al. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200507-1123oc · Cited by 406 · see citing works
Peters, A. (2001) · European Heart Journal · doi:10.1053/euhj.2000.2483 · Cited by 405 · see citing works
Ritz, B. R., Wilhelm, M. H., Hoggatt, K. J., & Ghosh, J. K. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm181 · Cited by 393 · see citing works
Self-citationSchins, R. P. F., Lightbody, J. H., Borm, P. J. A., Shi, T., Donaldson, K., & Stone, V. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2003.10.002 · Cited by 368 · see citing works
Wilhelm, M. H., & Ritz, B. R. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.5688 · Cited by 356 · see citing works
Self-citationDelfino, R. J., Staimer, N., Tjoa, T. T., Polidori, A., Arhami, M., Gillen, D. L., Kleinman, M. T., Vaziri, N. D., Longhurst, J. C., Zaldivar, F. P., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11189 · Cited by 356 · see citing works
Lung Inflammation Induced by Concentrated Ambient Air Particles Is Related to Particle Composition
Saldiva, P. H. N., Clarke, R. W., Coull, B. A., Stearns, R. C., Lawrence, J. E., Murthy, G. G. K., Diaz, E. A., Koutrakis, P., Suh, H. H., Tsuda, A., et al. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2106102 · Cited by 319 · see citing works
Wu, J. Y., Ren, C., Delfino, R. J., Chung, J. M., Wilhelm, M. H., & Ritz, B. R. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800334 · Cited by 276 · see citing works
Self-citationChronic Residential Exposure to Particulate Matter Air Pollution and Systemic Inflammatory Markers
Hoffmann, B. H., Moebus, S., Dragano, N., Stang, A., Möhlenkamp, S., Schmermund, A., Memmesheimer, M., Bröcker‐Preuß, M., Mann, K., Erbel, R., et al. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800362 · Cited by 250 · see citing works
Ambient Air Pollution and Adverse Birth Outcomes: Methodologic Issues in an Emerging Field
Ritz, B. R., & Wilhelm, M. H. (2008) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2007.00161.x · Cited by 244 · see citing works
Self-citationBarraza‐Villarreal, A., Sunyer, J., Cadena, L. H., Escamilla-Núñez, C., Sienra-Monge, J. J. L., Ramírez-Aguilar, M., Cortez‐Lugo, M., Holguín, F., Díaz-Sánchez, D., Olin, A. C., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10926 · Cited by 243 · see citing works
Wilhelm, M. H., & Ritz, B. R. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7751 · Cited by 239 · see citing works
Self-citationPlasma C-Reactive Protein in Early Pregnancy and Preterm Delivery
Pitiphat, W., Gillman, M. W., JOSHIPURA, K. J., Williams, P. L., Douglass, C. W., & Rich-Edwards, J. W. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi323 · Cited by 225 · see citing works
Xu, X., Ding, H., & Wang, X. (1995) · Archives of Environmental Health An International Journal · doi:10.1080/00039896.1995.9935976 · Cited by 216 · see citing works
Inflammatory markers and particulate air pollution: characterizing the pathway to disease
Zeka, A., Sullivan, J. R., Vokonas, P. S., Sparrow, D., & Schwartz, J. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl132 · Cited by 205 · see citing works
Space–time analysis using a general product–sum model
Iaco, S. D., Myers, D. E., & Posa, D. (2001) · Statistics & Probability Letters · doi:10.1016/s0167-7152(00)00200-5 · Cited by 195 · see citing works
C-reactive protein: history and revival
Ablij, H. C., & Meinders, A. E. (2002) · European Journal of Internal Medicine · doi:10.1016/s0953-6205(02)00132-2 · Cited by 177 · see citing works
Chen, L., Bell, E. M., Caton, A. R., Druschel, C. M., & Lin, S. (2010) · Environmental Research · doi:10.1016/j.envres.2009.11.001 · Cited by 163 · cited 2× · see citing works
“Because our study population was drawn from a longitudinal cohort, in which participants received their prenatal care and delivered in the same hospital, we believe that it is reasonable to assume that most women in our study either did not move or moved only within the same neighborhood (or zip code) during pregnancy…”
ResultThompson, A. M. S., Zanobetti, A., Silverman, F., Schwartz, J. D., Coull, B. A., Urch, B., Speck, M., Brook, J. R., Manno, M., & Gold, D. R. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900550 · Cited by 160 · see citing works
Panasevich, S., Leander, K., Rosenlund, M., Ljungman, P. L. S., Bellander, T., Fairé, U. D., Pershagen, G., & Nyberg, F. (2009) · Occupational and Environmental Medicine · doi:10.1136/oem.2008.043471 · Cited by 145 · see citing works
Inflammation and Dyslipidemia Related to Risk of Spontaneous Preterm Birth
Catov, J. M., Bodnar, L. M., Ness, R. B., Barron, S. J., & Roberts, J. M. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm273 · Cited by 144 · see citing works
Self-citationChronic Exposure to Outdoor Air Pollution and Markers of Systemic Inflammation
Forbes, L. J. L., Patel, M. D., Rudnicka, A. R., Cook, D. G., Bush, T., Stedman, J. R., Whincup, P. H., Strachan, D. P., & Anderson, R. (2009) · Epidemiology · doi:10.1097/ede.0b013e318190ea3f · Cited by 131 · see citing works
Increased cord serum inflammatory markers in small-for-gestational-age neonates
Amarilyo, G., Oren, A., Mimouni, F. B., Ochshorn, Y., Deutsch, V., & Mandel, D. (2010) · Journal of Perinatology · doi:10.1038/jp.2010.53 · Cited by 125 · see citing works
Air Pollution and Infant Death in Southern California, 1989–2000
Ritz, B. R., Wilhelm, M., & Zhao, Y. (2006) · PEDIATRICS · doi:10.1542/peds.2006-0027 · Cited by 123 · see citing works
Self-citationEffects of Ambient Air Pollution on Hemostasis and Inflammation
Rudež, G., Janssen, N., Kılınç, E., Leebeek, F. W. G., Gerlofs-Nijland, M. E., Spronk, H. M. H., Cate, H. T., Cassee, F. R., & de Maat, M. P. M. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800437 · Cited by 111 · see citing works
Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation
Saber, A. T., Bornholdt, J., Dybdahl, M., Sharma, A. K., Loft, S. H., Vogel, U. B., & Wallin, H. (2004) · Archives of Toxicology · doi:10.1007/s00204-004-0613-9 · Cited by 97 · see citing works
A local space–time kriging approach applied to a national outpatient malaria data set
Gething, P. W., Atkinson, P. M., Noor, A. M., Gikandi, P. W., Hay, S. I., & Nixon, M. S. (2007) · Computers & Geosciences · doi:10.1016/j.cageo.2007.05.006 · Cited by 86 · see citing works
C-Reactive Protein Is Elevated 30 Years After Eclamptic Pregnancy
Hubel, C. A., Powers, R. W., Snaedal, S., Gammill, H. S., Ness, R. B., Roberts, J. M., & Arngrı́msson, R. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.109934 · Cited by 79 · see citing works
Self-citationOxidative stress and inflammation in pregnancy
Fialová, L., Malbohan, I., Kalousová, M., Soukupová, J., Krofta, L., Štípek, S., & Zima, T. (2006) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510500375230 · Cited by 76 · see citing works
Neutrophil Activation and C‐Reactive Protein Concentration in Preeclampsia
Belo, L., Santos‐Silva, A., CASLAKE, M. J., Cooney, J., Pereira‐Leite, L., Quintanilha, A. T., & Rebelo, I. (2003) · Hypertension in Pregnancy · doi:10.1081/prg-120021059 · Cited by 72 · see citing works
Traffic-Related Air Pollution and Perinatal Mortality: A Case–Control Study
de Medeiros, A. P. P., Gouveia, N., Machado, R. P. P., de Souza, M. R., Alencar, G. P., Novaes, H. M. D., & de Almeida, M. F. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11679 · Cited by 69 · see citing works
Thornton, C. A. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s0029665110001886 · Cited by 27 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Bekkar, B., Pacheco, S. E., Basu, R., & DeNicola, N. G. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.8243 · Cited by 825 · see citing works
Johnson, N. M., Hoffmann, A. R., Behlen, J. C., Lau, C., Pendleton, D., Harvey, N., Shore, R., Li, Y., Chen, J., Tian, Y., et al. (2021) · Environmental Health and Preventive Medicine · doi:10.1186/s12199-021-00995-5 · Cited by 339 · see citing works
“5 exposure was associated with increased Creactive protein (CRP) concentrations in early pregnancy [165].”
BackgroundKlepac, P., Locatelli, I., Korošec, S., Künzli, N., & Kukec, A. (2018) · Environmental Research · doi:10.1016/j.envres.2018.07.008 · Cited by 345 · see citing works
Roberts, A. L., Lyall, K., Hart, J. E., Laden, F., Just, A. C., Bobb, J. F., Koenen, K. C., Ascherio, A., & Weisskopf, M. G. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1206187 · Cited by 306 · see citing works
Lee, P.-C., Roberts, J., Catov, J., Talbott, E., & Ritz, B. (2013) · Maternal and Child Health Journal · doi:10.1007/s10995-012-1028-5 · Cited by 223 · see citing works
Self-citationPreconception and early pregnancy air pollution exposures and risk of gestational diabetes mellitus
Robledo, C. A., Mendola, P., Yeung, E. H., Männistö, T. I., Sundaram, R., Liu, D., Ying, Q., Sherman, S. J., & Grantz, K. L. (2015) · Environmental Research · doi:10.1016/j.envres.2014.12.020 · Cited by 181 · see citing works
Effects of Environmental Exposures on Fetal and Childhood Growth Trajectories
Zheng, T., Zhang, J., Sommer, K., Bassig, B. A., Zhang, X., Braun, J., Shuang-qing, X., Boyle, P., Zhang, B., Shi, K., et al. (2016) · Annals of Global Health · doi:10.1016/j.aogh.2016.01.008 · Cited by 174 · see citing works
Nachman, R. M., Mao, G., Zhang, X., Hong, X., Chen, Z., Soria, C. S., He, H., Wang, G., Caruso, D., Pearson, C., et al. (2016) · Environmental Health Perspectives · doi:10.1289/ehp243 · Cited by 164 · see citing works
Air Pollution During Pregnancy and Neonatal Outcome: A Review
Proietti, E., Röösli, M., Frey, U., & Latzin, P. (2012) · Journal of Aerosol Medicine and Pulmonary Drug Delivery · doi:10.1089/jamp.2011.0932 · Cited by 157 · see citing works
Early life exposure to air pollution: How bad is it?
Backes, C. H., Nelin, T. D., Gorr, M. W., & Wold, L. E. (2012) · Toxicology Letters · doi:10.1016/j.toxlet.2012.11.007 · Cited by 155 · see citing works
PM2.5 Exposure and Birth Outcomes
Hyder, A., Lee, H. J., Ebisu, K., Koutrakis, P., Belanger, K. D., & Bell, M. L. (2013) · Epidemiology · doi:10.1097/ede.0000000000000027 · Cited by 150 · see citing works
Air Pollution Exposure and Abnormal Glucose Tolerance during Pregnancy: The Project Viva Cohort
Fleisch, A. F., Gold, D. R., Rifas‐Shiman, S. L., Koutrakis, P., Schwartz, J. D., Kloog, I., Melly, S. J., Coull, B. A., Zanobetti, A., Gillman, M. W., et al. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307065 · Cited by 143 · see citing works
Basu, R., Harris, M. H., Sie, L., Malig, B., Broadwin, R., & Green, R. S. (2013) · Environmental Research · doi:10.1016/j.envres.2013.10.008 · Cited by 126 · see citing works
van den Hooven, E. H., de Kluizenaar, Y., Pierik, F. H., Albert Hofman, D., van Ratingen, S. W., Zandveld, P. Y. J., Lindemans, J. W., Russcher, H., Steegers, E. A. P., Miedema, H., et al. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104345 · Cited by 112 · see citing works
Obesity and the cardiovascular health effects of fine particulate air pollution
Weichenthal, S., Hoppin, J. A., & Reeves, F. (2014) · Obesity · doi:10.1002/oby.20748 · Cited by 107 · see citing works
Ambient air pollution and adverse birth outcomes: A review of underlying mechanisms
Fussell, J. C., Jauniaux, E. R. M., Smith, R. B., & Burton, G. J. (2023) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.17727 · Cited by 102 · see citing works
Risk factors for placenta accreta spectrum: findings from the Japan environment and Children’s study
the Japan Environment and Children’s Study (JECS) Group, Kyozuka, H., Yamaguchi, A., Suzuki, D., Fujimori, K., Hosoya, M., Yasumura, S., Yokoyama, T., Satô, A., & Hashimoto, K. (2019) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-019-2608-9 · Cited by 96 · see citing works
Goodman, J. E., Prueitt, R. L., Sax, S. N., Pizzurro, D. M., Lynch, H. N., Zu, K., & Venditti, F. J. (2015) · Critical Reviews in Toxicology · doi:10.3109/10408444.2015.1031371 · Cited by 92 · see citing works
Erickson, A. C., & Arbour, L. (2014) · Journal of Environmental and Public Health · doi:10.1155/2014/901017 · Cited by 90 · see citing works
Prenatal fine particulate matter exposure, placental DNA methylation changes, and fetal growth
Zhao, Y., Wang, P., Zhou, Y., Xia, B., Zhu, Q., Ge, W., Li, J., Shi, H., Xiao, X., & Zhang, Y. (2020) · Environment International · doi:10.1016/j.envint.2020.106313 · Cited by 71 · see citing works
Lactation and maternal subclinical cardiovascular disease among premenopausal women
McClure, C. K., Catov, J. M., Ness, R. B., & Schwarz, E. B. (2012) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2012.04.030 · Cited by 68 · see citing works
Self-citationInoue, K., Yan, Q. J., Arah, O. A., Paul, K. C., Walker, D. I., Jones, D. P., & Ritz, B. R. (2020) · Current Environmental Health Reports · doi:10.1007/s40572-020-00284-3 · Cited by 66 · see citing works
Self-citationPrenatal exposure to ambient air pollution is associated with early life immune perturbations
Pedersen, C. T., Eliasen, A. U., Ketzel, M., Brandt, J. G., Loft, S. H., Frohn, L. M., Khan, J., Brix, S., Rasmussen, M. A., Stokholm, J., et al. (2022) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2022.08.020 · Cited by 61 · see citing works
The association of PM2.5 with full term low birth weight at different spatial scales
Harris, G., Thompson, W. D., Fitzgerald, E. F., & Wartenberg, D. E. (2014) · Environmental Research · doi:10.1016/j.envres.2014.05.034 · Cited by 62 · see citing works
Prenatal air pollution exposure and ultrasound measures of fetal growth in Los Angeles, California
Ritz, B. R., Qiu, J., Lee, P., Lurmann, F. W., Penfold, B. M., Weiss, R. E., McConnell, R., Arora, C., Hobel, C. J., & Wilhelm, M. H. (2014) · Environmental Research · doi:10.1016/j.envres.2014.01.006 · Cited by 60 · see citing works
Self-citationA Potential Role for Allostatic Load in Preeclampsia
Hux, V. J., & Roberts, J. M. (2014) · Maternal and Child Health Journal · doi:10.1007/s10995-014-1543-7 · Cited by 57 · see citing works
Self-citationMorales-Ancajima, V. C., Tapia, V., Vu, B. N., Liu, Y., Alarcón-Yaquetto, D. E., & Gonzales, G. F. (2019) · Journal of Environmental and Public Health · doi:10.1155/2019/6127845 · Cited by 57 · see citing works
de Oliveira, B. F. A., Chacra, A. P. M., Frauches, T. S., Vallochi, A. L., & Hacon, S. D. S. (2014) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2014.976893 · Cited by 47 · see citing works
Slama, R., Ballester, F., Casas, M., Cordier, S., Eggesbø, M. Å., Íñiguez, C., Nieuwenhuijsen, M. J., Philippat, C., Rey, S., Vandentorren, S., et al. (2013) · Epidemiologic Reviews · doi:10.1093/epirev/mxt011 · Cited by 46 · see citing works
CRITICAL REVIEW OF AIR POLLUTION HEALTH EFFECTS WITH SPECIAL CONCERN ON RESPIRATORY HEALTH
Khafaie, M. A., Yajnik, C. S., Salvi, S., & Ojha, A. R. (2016) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 47 · see citing works
Carvalho, M. A., Bernardes, L. S., Hettfleisch, K., Pastro, L. D. M., Vieira, S. E., Saldiva, S. R. D. M., Saldiva, P. H. N., & Francisco, R. P. V. (2016) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.04.013 · Cited by 46 · see citing works
Friedman, C., Dabelea, D., Thomas, D. S. K., Peel, J. L., Adgate, J. L., Magzamen, S. L., Martenies, S. E., Allshouse, W. B., & Starling, A. P. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111165 · Cited by 45 · see citing works
Shang, L., Huang, L., Yang, W., Qi, C., Yang, L., Xin, J., Wang, S., Li, D., Wang, B., Zeng, L., et al. (2019) · BMC Public Health · doi:10.1186/s12889-019-7790-1 · Cited by 45 · see citing works
Chen, J., Li, P., Fan, H., Li, C., Zhang, Y., Ju, D., Deng, F., Guo, X., Guo, L., & Wu, S. (2021) · International Journal of Epidemiology · doi:10.1093/ije/dyab166 · Cited by 44 · see citing works
Bastain, T. M., Chavez, T., Habre, R., Hernandez‐Castro, I., Grubbs, B. H., Toledo‐Corral, C. M., Farzan, S. F., Lurvey, N., Lerner, D. L., Eckel, S. P., et al. (2021) · Environmental Health · doi:10.1186/s12940-021-00807-x · Cited by 42 · see citing works
Particle air pollution and gestational diabetes mellitus in Houston, Texas
Rammah, A., Whitworth, K. W., & Symanski, E. (2020) · Environmental Research · doi:10.1016/j.envres.2020.109988 · Cited by 42 · see citing works
Männistö, T. I., Mendola, P., Liu, D., Leishear, K., Sherman, S. J., & Laughon, S. K. (2014) · American Journal of Hypertension · doi:10.1093/ajh/hpu077 · Cited by 39 · see citing works
Zhang, R.-D., Chen, C., Wang, P., Fang, Y., Jiang, L.-Q., Fang, X., Zhao, Y., Ni, J., Wang, D., & Pan, H. (2023) · Environmental Geochemistry and Health · doi:10.1007/s10653-023-01495-x · Cited by 41 · see citing works
Rahmalia, A., Giorgis-Allemand, L., Lepeule, J., Philippat, C., Galineau, J., Hulin, A., Charles, M.-A. A., & Slama, R. (2012) · Environment International · doi:10.1016/j.envint.2012.06.013 · Cited by 39 · see citing works
Ozone and hypertensive disorders of pregnancy in Florida: Identifying critical windows of exposure
Hu, H. Z., Ha, S., & Xu, X. (2016) · Environmental Research · doi:10.1016/j.envres.2016.12.002 · Cited by 40 · see citing works
Michikawa, T., Morokuma, S., Fukushima, K., Kato, K., Nitta, H., & Yamazaki, S. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.06.069 · Cited by 39 · see citing works
The Association Between Air Pollution and Low Birth Weight and Preterm Labor in Ahvaz, Iran
Sarizadeh, R., Dastoorpoor, M., Goudarzi, G., & Simbar, M. (2020) · International Journal of Women s Health · doi:10.2147/ijwh.s227049 · Cited by 38 · see citing works
Su, X., Zhang, S., Lin, Q., Wu, Y., Yang, Y., Yu, H., Huang, S., Luo, W., Wang, X., Lin, H., et al. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.151658 · Cited by 38 · see citing works
Ambient PM2.5 exposures and systemic inflammation in women with early pregnancy
Zhang, B., Gong, X., Han, B., Chu, M., Gong, C., Yang, J., Chen, L., Wang, J., Bai, Z., & Zhang, Y. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154564 · Cited by 39 · see citing works
Laine, J. E., Bodinier, B., Robinson, O., Plusquin, M., Scalbert, A., Keski‐Rahkonen, P., Robinot, N. R., Vermeulen, R. C. H., Pizzi, C., Asta, F., et al. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.0c02657 · Cited by 37 · see citing works
Olsson, D., Ekström, M., & Forsberg, B. (2012) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph9010272 · Cited by 37 · see citing works
Maternal Exposure to PM2.5 Affects Fetal Lung Development at Sensitive Windows
Yue, H., Ji, X., Li, G., Hu, M., & Sang, N. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b04674 · Cited by 35 · see citing works
Ambient fine particulate matter exposures and human early placental inflammation
Gong, C., Chu, M., Yang, J., Gong, X., Han, B., Chen, L., Bai, Z., Wang, J., & Zhang, Y. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.120446 · Cited by 34 · see citing works
Impact of air pollution on low birth weight in Spain: An approach to a National Level Study
Arroyo, V., Díaz, J., Salvador, P., & Linares, C. (2019) · Environmental Research · doi:10.1016/j.envres.2019.01.030 · Cited by 33 · see citing works
Williams, A., Grantz, K. L., Zhang, C., Nobles, C. J., Sherman, S. J., & Mendola, P. (2018) · American Journal of Epidemiology · doi:10.1093/aje/kwy256 · Cited by 30 · see citing works
Michikawa, T., Morokuma, S., Yamazaki, S., Fukushima, K., Kato, K., & Nitta, H. (2016) · Environment International · doi:10.1016/j.envint.2016.04.037 · Cited by 31 · see citing works
Ren, Y., Yao, X., Liu, Y., Liu, S., Li, X., Huang, Q., Liu, F., Li, N., Lu, Y., Yuan, Z., et al. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-018-3715-2 · Cited by 30 · see citing works
Biomarkers used in studying air pollution exposure during pregnancy and perinatal outcomes: a review
Desai, G. S., Chu, L., Guo, Y., Myneni, A. A., & Mu, L. (2017) · Biomarkers · doi:10.1080/1354750x.2017.1339294 · Cited by 29 · see citing works
Tan, Y., Liao, J., Zhang, B., Mei, H., Peng, A., Zhao, J., Zhang, Y., Yang, S., & He, M. (2020) · Environmental Research · doi:10.1016/j.envres.2020.110627 · Cited by 28 · see citing works
Traffic pollution at the home address and pregnancy outcomes in Stockholm, Sweden
Olsson, D., Mogren, I., Eneroth, K., & Forsberg, B. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007034 · Cited by 28 · see citing works
Wang, Y., Duan, H., Meng, T., Shen, M., Ji, Q., Xing, J., Wang, Q., Wang, T., Niu, Y., Yu, T., et al. (2017) · Environment International · doi:10.1016/j.envint.2017.12.024 · Cited by 27 · see citing works
Premature births in Spain: Measuring the impact of air pollution using time series analyses
Arroyo, V., Linares, C., & Díaz, J. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.12.470 · Cited by 25 · see citing works
Wang, J., Zeng, Y., Ni, Z., Gui, W., Liu, S., Li, C., Yu, C.-L., Wang, Q., & Nie, S. (2017) · Journal of Huazhong University of Science and Technology [Medical Sciences] · doi:10.1007/s11596-017-1729-5 · Cited by 24 · see citing works
Rammah, A., Whitworth, K. W., Amos, C. I., Estarlich, M., Guxens, M., Ibarluzea, J. M., Íñiguez, C., Subiza‐Pérez, M., Vrijheid, M., & Symanski, E. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18179354 · Cited by 23 · see citing works
Ambient air pollution and endocrinologic disorders in childhood
Heo, Y. J., & Kim, H. S. (2021) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2142132.066 · Cited by 23 · see citing works
An exposure-response meta-analysis of ambient PM2.5 during pregnancy and preeclampsia
Gogna, P., Villeneuve, P. J., Borghese, M. M., & King, W. D. (2022) · Environmental Research · doi:10.1016/j.envres.2022.112934 · Cited by 22 · see citing works
Slama, R., & Cordier, S. (2013) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2013.02.012 · Cited by 22 · see citing works
Hao, H., Yoo, S.-R., Strickland, M., Darrow, L., D'Souza, R., Warren, J. L., Moss, S. E., Wang, H.-Q., Zhang, H.-S., & Chang, H. H. (2023) · Scientific Reports · doi:10.1038/s41598-023-48329-5 · Cited by 19 · see citing works
Cowell, W., Brunst, K. J., Malin, A. J., Coull, B. A., Gennings, C., Kloog, I., Lipton, L. R., Wright, R. O., Enlow, M. B., & Wright, R. J. (2019) · Environmental Health Perspectives · doi:10.1289/ehp4434 · Cited by 21 · see citing works
Liu, Y., Li, L., Xie, J., Jiao, X. C., Hu, H., Zhang, Y., Tao, R., Tao, F., & Zhu, P. (2021) · Environment International · doi:10.1016/j.envint.2021.106460 · Cited by 20 · see citing works
Ambient air pollution and inflammatory effects in a Canadian pregnancy cohort
Gogna, P., King, W. D., Villeneuve, P. J., Kumarathasan, P., Johnson, M., Lanphear, B. P., Shutt, R., Arbuckle, T. E., & Borghese, M. M. (2021) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000168 · Cited by 20 · see citing works
Liu, R., Zhang, J., Chu, L., Zhang, J., Guo, Y., Qiao, L., Niu, Z., Wang, M., Farhat, Z., Grippo, A., et al. (2022) · Environmental Research · doi:10.1016/j.envres.2022.114008 · Cited by 19 · see citing works
Huang, C., Liu, C., Chen, M., Tsao, P., Chen, C., Chou, H., & Chen, P. (2019) · Pediatrics & Neonatology · doi:10.1016/j.pedneo.2019.11.008 · Cited by 19 · see citing works
Zordão, O. P., Campolim, C. M., Yariwake, V. Y., Castro, G., Ferreira, C. K. D. O., Santos, A., Norberto, S., Veras, M. M., Saad, M. J. A., Saldiva, P. H. N., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1069243 · Cited by 19 · see citing works
Hung, T., Hsu, T., Tung, T., Tsai, C., Ou, C., Chung, F.-F., & Wan, G. (2021) · Environmental Research · doi:10.1016/j.envres.2021.110921 · Cited by 18 · see citing works
Liu, W., Zhang, Q., Qiu, C., & Qiu, C. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-22379-0 · Cited by 17 · see citing works
Particulate matter : sources, emission rates, and health effects
Knudsen, H. N., & Rasmussen, N. (2012) · Nova Science Publishers eBooks · Cited by 17 · see citing works
Soesanti, F., Uiterwaal, C. S. P. M., Meliefste, K., Chen, J., Brunekreef, B., Idris, N. S., Grobbee, D. E., Klipstein‐Grobusch, K., & Hoek, G. (2023) · Environmental Health · doi:10.1186/s12940-023-00973-0 · Cited by 16 · see citing works
Role of infant sex in the association between air pollution and preterm birth
Cossi, M., Zuta, S., Padula, A. M., Gould, J. B., Stevenson, D. K., & Shaw, G. M. (2015) · Annals of Epidemiology · doi:10.1016/j.annepidem.2015.08.005 · Cited by 16 · see citing works
Ehrenstein, O. S. V., Wilhelm, M. H., & Ritz, B. R. (2013) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e31829888fe · Cited by 16 · see citing works
Self-citationPayne-Sturges, D., Puett, R. C., & Cory‐Slechta, D. A. (2022) · Environmental Health · doi:10.1186/s12940-022-00856-w · Cited by 14 · see citing works
Ekland, J., Olsson, D., Forsberg, B., Andersson, C., & Orru, H. (2021) · Environmental Research Letters · doi:10.1088/1748-9326/abe6c4 · Cited by 14 · see citing works
Gogna, P., Borghese, M. M., Villeneuve, P. J., Kumarathasan, P., Johnson, M., Shutt, R., Ashley‐Martin, J., Bouchard, M. F., & King, W. D. (2024) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000308 · Cited by 12 · see citing works
Maternal Smoking and the Risk of Placenta Accreta Spectrum: A Systematic Review and Meta‐Analysis
Jenabi, E., Salehi, A. M., Masoumi, S. Z., & Maleki, A. (2022) · BioMed Research International · doi:10.1155/2022/2399888 · Cited by 10 · see citing works
Moore, B., Starling, A., Martenies, S. E., Magzamen, S., & Dabelea, D. (2021) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000142 · Cited by 6 · see citing works
Neighbourhood assets and early pregnancy cardiometabolic risk factors
Assibey‐Mensah, V., Fabio, A., Méndez, D. D., Lee, P., Roberts, J. M., & Catov, J. M. (2019) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12531 · Cited by 9 · see citing works
Self-citationHu, J., Wan, N., Ma, Y., Liu, Y., Liu, B., Li, L., Liu, C., Qiao, C., & Wen, D. (2022) · Indoor Air · doi:10.1111/ina.13167 · Cited by 8 · see citing works
Chang, S. Y., Vizuete, W., Breen, M. S., Isakov, V., & Arunachalam, S. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph121215007 · Cited by 8 · see citing works
Williams, A., Ha, S., Shenassa, E. D., Messer, L. C., Kanner, J., & Mendola, P. (2021) · Environmental Health · doi:10.1186/s12940-021-00738-7 · Cited by 8 · see citing works
Association between maternal exposure to particulate matter and premature birth
Nascimento, L. F. C., de Lima, T. A. C., de Medeiros, A. P. P., & Santos, V. D. P. (2014) · Ambiente e Agua - An Interdisciplinary Journal of Applied Science · doi:10.4136/ambi-agua.1262 · Cited by 7 · see citing works
Zhang, T., Jiang, W., Huang, Y., Wang, C., Cao, J., Qiu, W., Huang, R., Zhang, J., Ye, W., & Zhang, Q. (2025) · BMC Public Health · doi:10.1186/s12889-025-22913-y · Cited by 6 · see citing works
Yamaguchi, T., Kyozuka, H., Ito, M., Hiraiwa, T., Murata, T., Sugeno, M., Ito, F., Suzuki, D., Fukuda, T., Yasuda, S., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0306488 · Cited by 6 · see citing works
Orenshtein, S., Sheiner, E., Kloog, I., & Wainstock, T. (2023) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2023.101050 · Cited by 6 · see citing works
Soesanti, F., Hoek, G., Brunekreef, B., Meliefste, K., Chen, J., Idris, N. S., Putri, N. D., Uiterwaal, C. S. P. M., Grobbee, D. E., & Klipstein‐Grobusch, K. (2024) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-024-02064-0 · Cited by 5 · see citing works
Zhang, Y., Rosen, R. L., Reibman, J., & Shao, Y. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19148622 · Cited by 5 · see citing works
Valid predictions with confidence estimation in an air pollution problem
Ivina, O., Nouretdinov, I., & Gammerman, A. (2012) · Progress in Artificial Intelligence · doi:10.1007/s13748-012-0018-6 · Cited by 4 · see citing works
Tong, M., Lin, W., Liu, H., Gong, J., Zhang, J. J., & Xue, T. (2023) · Environmental Health · doi:10.1186/s12940-023-01016-4 · Cited by 4 · see citing works
Ambient air pollution and the fetus
Yurdakök, K. (2013) · Journal of pediatric and neonatal individualized medicine · doi:10.7363/020232 · Cited by 4 · see citing works
From exposure to outcomes: How air pollutants impact maternal and foetal health
Parikh, G., & Patel, B. M. (2025) · Reproductive Toxicology · doi:10.1016/j.reprotox.2025.109080 · Cited by 3 · see citing works
Hu, J., Liu, Y., Ma, Y., Gao, M., Wan, N., Li, L., Liu, B., & Wen, D. (2022) · Indoor Air · doi:10.1111/ina.13124 · Cited by 3 · see citing works
Lin, J., Shen, Y., Wu, F., Zhu, Q., Huang, J., Cai, J., & Lin, J. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.176014 · Cited by 3 · see citing works
Synergistic Impact of Air Pollution and Heat on Health and Economy in India
Sekar, A., Sharma, R. K., & Mahajan, A. (2024) · Springer eBooks · doi:10.1007/978-3-031-56564-9_2 · Cited by 2 · see citing works
Self-citationBrink, L. L., Benson, S. M., Marshall, L. P., & Talbott, E. O. (2014) · Journal of Racial and Ethnic Health Disparities · doi:10.1007/s40615-014-0018-2 · Cited by 2 · see citing works
Self-citationLaine, M. K., Kautiainen, H., Anttila, P., Gissler, M., Pennanen, P., & Eriksson, J. G. (2022) · Primary care diabetes · doi:10.1016/j.pcd.2022.11.012 · Cited by 2 · see citing works
- Authors
- Lee, P.-C., Talbott, E. O., Roberts, J. M., Catov, J. M., Sharma, R. K., & Ritz, B.
- Affiliations
- University of Pittsburgh (US)
- University of California, Los Angeles (US)
- Corresponding author
- Lee, Pei-Chen
- Venue
- Epidemiology
- Published
- 2011-07
- Volume
- 22
- Issue
- 4
- Pages
- 524-531
- ISSN
- 1044-3983 (ISSN-L)
- PMC
- PMC4325994
- OpenAlex
- W1994603238
- Cited by
- 118
- References
- 41
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 6 · 2023: 13 · 2022: 13 · 2021: 15 · 2020: 7 · 2019: 9 · 2018: 3 · 2017: 4 · 2016: 6 · 2015: 5 · 2014: 13 · 2013: 7 · 2012: 9
- FWCI
- 7.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD030367)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Social Sciences › Sociology and Political Science › Environmental Justice and Health Disparities
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Keywords
- particulate matter, PM10, PM2.5, C-reactive protein, early pregnancy, maternal air pollution exposure, systemic inflammation, ozone, carbon monoxide, nitrogen dioxide, sulfur dioxide, preterm birth, adverse pregnancy outcomes, smoking, obesity
- MeSH terms
- Adult, Air Pollutants, Air Pollution, C-Reactive Protein, Carbon Monoxide, Female, Humans, Longitudinal Studies, Nitrogen Dioxide, Ozone, Pennsylvania, Pregnancy, Pregnancy Outcome, Sulfur Dioxide, Logistic Models, Maternal Exposure, Particulate Matter
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
