Cited by 30Hormonal and reproductive studiesMenopause: Health Impacts and TreatmentsAdrenal Hormones and Disorders

Testosterone correlated to symptoms of partial androgen deficiency in aging men (PADAM) in an elderly Swedish population

Spetz, Anna-Clara E., Palmefors, Lennart, Skobe, R. Staffan P., Strömstedt, Martin T., Fredriksson, Mats G., Theodorsson, Elvar, Hammar, Mats L.·2007·Menopause

Abstract

OBJECTIVE: To investigate the prevalence of different symptoms of partial androgen deficiency in aging men (PADAM) and to correlate them with blood concentrations of testosterone and bioavailable testosterone. DESIGN: A total of 370 men, aged 55 to 75 years, were invited to one of three primary healthcare centers in Sweden. They were asked to complete a questionnaire regarding demographic data, medical history, mood status, medication, castration therapy and smoking, exercise and alcohol habits, as well as different symptoms of PADAM. The 10 questions from a previously used questionnaire (the ADAM questionnaire) were included. The men were offered blood tests for analyses of testosterone, follicle stimulating hormone, luteinizing hormone, steroid hormone-binding globulin, and albumin. From these test results, we calculated the bioavailable testosterone. RESULTS: Of the questionnaires sent out, 81.6% were returned and eligible for evaluation. Blood samples were obtained from 85.8% of men answering the questionnaire. Many of the symptoms, including five from the ADAM questionnaire, were more common in older age groups (P < 0.05). Three symptoms, deterioration in work performance, decreased strength and/or endurance, and bothersome hot flushes, were associated with low bioavailable testosterone and/or testosterone (P < 0.05). Testosterone and bioavailable testosterone did not differ between age groups, but bioavailable testosterone was higher in men with three or fewer symptoms on the ADAM questionnaire. CONCLUSIONS: Symptoms associated with PADAM often occur in an elderly population, but we could only find an association between three symptoms and blood testosterone concentrations, one being bothersome hot flushes. It is likely that these symptoms have a more complex background than only PADAM.

Integrity signals

Registry

Crossref · 10.1097/gme.0b013e318057786b

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

1 of the 28 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Spetz, A.-C. E., Palmefors, L., Skobe, R. S. P., Strömstedt, M. T., Fredriksson, M. G., Theodorsson, E., & Hammar, M. L.
Affiliations
  • Linköping University (SE)
  • Linköping University Hospital (SE)
Corresponding author
Spetz, Anna-Clara E.
Venue
Menopause
Published
2007-11
Volume
14
Issue
6
Pages
999-1005
ISSN
1072-3714 (ISSN-L)
OpenAlex
W2018221577
Cited by
30
References
28
Citations by year
2024: 1 · 2016: 1 · 2014: 3 · 2013: 2 · 2012: 7
FWCI
3.66
Type
journal article
Language
en
Open access
closed
Locations
  • Menopause The Journal of The North American Menopause Society (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
testosterone, bioavailable testosterone, ADAM questionnaire, hot flashes, employee performance, muscle strength and endurance, older men, hormone replacement therapy
MeSH terms
Aged, Aging, Cross-Sectional Studies, Humans, Male, Middle Aged, Surveys and Questionnaires, Severity of Illness Index, Sweden, Testosterone, Hot Flashes, Andropause

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review