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Depression and Depressive Symptoms in Pediatric Traumatic Brain Injury: A Scoping Review
Abstract
Objective: This scoping review aimed to summarize the existing knowledge base regarding depression and depressive symptoms in pediatric traumatic brain injury (TBI) and to identify gaps in the literature in an effort to guide future research. Methods: MEDLINE Ovid and PsycINFO Ovid databases were each searched by the authors using search terms intended to identify any original research study that examined depressive symptoms in children (ie, aged 0-18 years) with TBI. Results: A total of 14 published studies were included in the review. The studies included examined the prevalence of depression, risk factors associated with depression, and depression as a predictor of other TBI-related outcomes. Conclusion: Existing research suggests that depressive symptoms are more common in a TBI population than in a healthy or orthopedically injured population. Injury-related factors such as lesions in the brain and the presence of pain, as well as noninjury factors such as older age at injury and low socioeconomic status, may be predictive of depressive symptoms. Depression is likely a secondary outcome of pediatric TBI rather than a direct result of the injury itself. Overall, a relative dearth of research exists on this topic; thus, the review concludes by proposing future research directions.
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“Children younger than 10 years are at a particular high risk for TBI, yet the risk this injury poses for subsequent mood and anxiety disorders in this population is the least defined.1,13”
From Long-Term Risk for Mood and Anxiety Disorders After Pediatric Traumatic Brain Injury: A Population-Based, Birth Cohort Analysis (2023) · cites this paper as [13]
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“However, the risk of developing clinically determined mood and anxiety disorders greater than 5 years after pediatric TBI and into adulthood remains unclear.13–15”
From Long-Term Risk for Mood and Anxiety Disorders After Pediatric Traumatic Brain Injury: A Population-Based, Birth Cohort Analysis (2023) · cites this paper as [13]
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Short- and long-term social outcomes following pediatric traumatic brain injury
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Cited by
Lambert, M., Sheldrake, E., Deneault, A.-A., Wheeler, A., Burke, M., & Scratch, S. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.48453 · Cited by 51
Botchway, E. N., Godfrey, C., Ryan, N. P., Hearps, S., Nicholas, C. L., Anderson, V. A., & Catroppa, C. (2020) · Brain Injury · doi:10.1080/02699052.2020.1832704 · Cited by 11
Exploring emotional distress symptom clusters in young adults with childhood traumatic brain injury
Botchway-Commey, E., Ryan, N. P., Anderson, V., & Catroppa, C. (2025) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2024.2375803 · Cited by 3
Esterov, D., Witkowski, J., McCall, D. M., Weaver, A. L., & Brown, A. W. (2023) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000825 · Cited by 3
Botchway‐Commey, E., Ryan, N. P., Crowe, L., Godfrey, C., Macleod, H., Hearps, S., Anderson, V. A., & Catroppa, C. (2026) · Journal of Neuropsychology · doi:10.1111/jnp.70042
Luszawski, C. A., Luszawski, M. M., Bender, A. M., Noel, M., & Yeates, K. O. (2026) · Journal of Neurotrauma · doi:10.1177/08977151261425214
Self-citation
Metadata
- Authors
- Laliberté Durish, C., Pereverseff, R. S., & Yeates, K. O.
- Venue
- Journal of Head Trauma Rehabilitation
- Published
- 2018-05
- Volume
- 33
- Issue
- 3
- Pages
- E18-E30
- ISSN
- 0885-9701
- Cited by
- 63
- References
- 4
- Language
- en
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