Placebo 2.0: the impact of expectations on analgesic treatment outcome

View Through a Window May Influence Recovery from Surgery

Ulrich, R. S. (1984) · Science · doi:10.1126/science.6143402 · Cited by 5,341

Placebo-Induced Changes in fMRI in the Anticipation and Experience of Pain

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An fMRI-Based Neurologic Signature of Physical Pain

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Placebo and Opioid Analgesia-- Imaging a Shared Neuronal Network

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THE MECHANISM OF PLACEBO ANALGESIA

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Corticostriatal functional connectivity predicts transition to chronic back pain

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Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems

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Towards a theory of chronic pain

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Changing illness perceptions after myocardial infarction: an early intervention randomized controlled trial

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The neuroscience of placebo effects: connecting context, learning and health

Wager, T. D., & Atlas, L. Y. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3976 · Cited by 844

Recommendations for the development, implementation, and reporting of control interventions in efficacy and mechanistic trials of physical, psychological, and self-management therapies: the CoPPS Statement

Hohenschurz‐Schmidt, D., Vase, L., Scott, W., Annoni, M., Ajayi, O. K., Barth, J., Bennell, K. L., Berna, C., Bialosky, J. E., BRAITHWAITE, F., et al. (2023) · BMJ · doi:10.1136/bmj-2022-072108 · Cited by 110

Neural circuit basis of placebo pain relief

Chen, C., Niehaus, J. K., Dinç, F., Huang, K. L., Barnette, A. L., Tassou, A., Shuster, S. A., Wang, L., Lemire, A. L., Menon, V., et al. (2024) · Nature · doi:10.1038/s41586-024-07816-z · Cited by 91

Expectancy Effects in Psychedelic Trials

Szigeti, B., & Heifets, B. D. (2024) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2024.02.004 · Cited by 81

Placebo and nocebo effects and mechanisms associated with pharmacological interventions: an umbrella review

Frisaldi, E., Shaibani, A. I., Benedetti, F., & Pagnini, F. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-077243 · Cited by 54

Local brain oscillations and interregional connectivity differentially serve sensory and expectation effects on pain

Bott, F. S., Nickel, M. M., Hohn, V. D., May, E. S., Ávila, C. G., Tiemann, L., Groß, J., & Ploner, M. (2023) · Science Advances · doi:10.1126/sciadv.add7572 · Cited by 36

Placebo and nocebo effects: from observation to harnessing and clinical application

Tu, Y., Zhang, L., & Kong, J. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02293-2 · Cited by 34

Pain, from perception to action: A computational perspective

Chen, Z. S., & Wang, J. (2022) · iScience · doi:10.1016/j.isci.2022.105707 · Cited by 38

The Nocebo Effect: A Review of Contemporary Experimental Research

Bagarić, B., Jokić‐Begić, N., & Jokić, C. S. (2021) · International Journal of Behavioral Medicine · doi:10.1007/s12529-021-10016-y · Cited by 29

The influence of psychological traits and prior experience on treatment expectations

Basedow, L. A., Fischer, A., Benson, S., Bingel, U., Brassen, S., Büchel, C., Engler, H., Mueller, E. M., Schedlowski, M., & Rief, W. (2023) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2023.152431 · Cited by 32

Music-Induced Analgesia in Healthy Participants Is Associated With Expected Pain Levels but Not Opioid or Dopamine-Dependent Mechanisms

Lunde, S. J., Vuust, P., Garza‐Villarreal, E. A., Kirsch, I., Møller, A., & Vase, L. (2022) · Frontiers in Pain Research · doi:10.3389/fpain.2022.734999 · Cited by 24

No long-term effects after a 3-week open-label placebo treatment for chronic low back pain: a 3-year follow-up of a randomized controlled trial

Kleine‐Borgmann, J., Dietz, T.-N., Schmidt, K., & Bingel, U. (2022) · Pain · doi:10.1097/j.pain.0000000000002752 · Cited by 23

Working with patients’ treatment expectations – what we can learn from homeopathy

Wilhelm, M., Hermann, C., Rief, W., Schedlowski, M., Bingel, U., & Winkler, A. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1398865 · Cited by 23

Observing treatment outcomes in other patients can elicit augmented placebo effects on pain treatment: a double-blinded randomized clinical trial with patients with chronic low back pain

Schwartz, M., Fischer, L., Bläute, C., Stork, J., Colloca, L., Zöllner, C., & Klinger, R. (2021) · Pain · doi:10.1097/j.pain.0000000000002513 · Cited by 22

Effects of Patients’ Expectation in Dermatology: Evidence from Experimental and Clinical Placebo Studies and Implications for Dermatologic Practice and Research

Sondermann, W., Jockenhöfer, F., Dissemond, J., Pfaar, O., Bingel, U., & Schedlowski, M. (2021) · Dermatology · doi:10.1159/000513445 · Cited by 22

The beneficial effect of positive treatment expectations on pharmacological migraine prophylaxis

Schmidt, K., Berding, T., Kleine‐Borgmann, J., Engler, H., Holle, D., Gaul, C., & Bingel, U. (2021) · Pain · doi:10.1097/j.pain.0000000000002341 · Cited by 21

How do placebo effects contribute to mindfulness-based analgesia? Probing acute pain effects and interactions using a randomized balanced placebo design

Davies, J. N., Sharpe, L., Day, M. A., & Colagiuri, B. (2022) · Pain · doi:10.1097/j.pain.0000000000002593 · Cited by 18

Expectations: How and when do they contribute to placebo analgesia?

Rosenkjær, S., Lunde, S. J., Kirsch, I., & Vase, L. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.817179 · Cited by 17

The role of expectations in transformative experiences

Villiger, D. (2022) · Philosophical Psychology · doi:10.1080/09515089.2022.2070063 · Cited by 16

Open-label placebo treatment does not enhance cognitive abilities in healthy volunteers

Hartmann, H., Forkmann, K., Schmidt, K., Kleine‐Borgmann, J., Albers, J., Wiech, K., & Bingel, U. (2023) · Scientific Reports · doi:10.1038/s41598-023-45979-3 · Cited by 13

Placebo induced expectations of mood enhancement generate a positivity effect in emotional processing

Baker, J., Gamer, M., Rauh, J., & Brassen, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-09342-2 · Cited by 15

Does pain modality play a role in the interruptive function of acute visceral compared with somatic pain?

Kleine‐Borgmann, J., Schmidt, K., Scharmach, K., Zunhammer, M., Elsenbruch, S., Bingel, U., & Forkmann, K. (2021) · Pain · doi:10.1097/j.pain.0000000000002418 · Cited by 14

Impact of the COVID ‐19 pandemic on patients with chronic pain in Germany: Associations with expectations and control beliefs

Müßgens, D., Burgard, L. C., Kleine‐Borgmann, J., Frettlöh, J., Sorgatz, H., & Bingel, U. (2022) · European Journal of Pain · doi:10.1002/ejp.1955 · Cited by 12

Patient Expectations for Synchronous Telerehabilitation Visits: A Survey Study of Telerehabilitation-Naive Patients

Peterson, S., Young, J. L., King, V., & Meadows, J. (2021) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2021.0083 · Cited by 12

Pre-treatment expectations and their influence on subjective symptom change in Crohn's disease

Basedow, L. A., Zerth, S. F., Salzmann, S., Uecker, C., Bauer, N., Elsenbruch, S., Rief, W., & Langhorst, J. (2023) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2023.111567 · Cited by 13

Erwartungsfokussierte psychotherapeutische Interventionen bei Depression: ein Behandlungsmanual

Wilhelm, M., Bleichhardt, G. M., Ewen, A.-C. I., & Rief, W. (2022) · Psychotherapeut · doi:10.1007/s00278-022-00590-1 · Cited by 10

Prehabilitation: The underutilised weapon for chronic pain management

Tidmarsh, L. V., Harrison, R. N., & Finlay, K. A. (2024) · British Journal of Pain · doi:10.1177/20494637241250239 · Cited by 10

Educational needs and preferences of adult patients with acute pain: a mixed-methods systematic review

Berube, M., Verret, M., Bourque, L., Côté, C. L., Guénette, L., Richard‐Denis, A., Ouellet, S., Singer, L. N., Gauthier, L. R., Gagnon, M., et al. (2024) · Pain · doi:10.1097/j.pain.0000000000003288 · Cited by 10

Ergebnisse einer Pilotstudie zur Rolle der Therapieerwartung bei der interdisziplinären multimodalen Schmerztherapie bei chronischem Rückenschmerz

Maser, D., Müller, D., Bingel, U., & Müßgens, D. (2021) · Der Schmerz · doi:10.1007/s00482-021-00590-1 · Cited by 10

Individual treatment expectations predict clinical outcome after lumbar injections against low back pain

Müller-Schrader, M., Heinzle, J., Müller, A. E., Lanz, C., Häussler, O., Sutter, M. A., Eggspuehler, A., Mare, S., Toussaint, B., Pereira, I., et al. (2022) · Pain · doi:10.1097/j.pain.0000000000002674 · Cited by 10

Personalised exercise therapy and self-management support for people with multimorbidity: Development of the MOBILIZE intervention

Bricca, A., Jäger, M., Dideriksen, M., Rasmussen, H., Nyberg, M., Pedersen, J. R., Zangger, G., Andreasson, K. H., & Skou, S. T. (2022) · Pilot and Feasibility Studies · doi:10.1186/s40814-022-01204-y · Cited by 11

How side effects can improve treatment efficacy: a randomized trial

Schenk, L. A., Fadai, T., & Büchel, C. (2024) · Brain · doi:10.1093/brain/awae132 · Cited by 10

Learning by observing: a systematic exploration of modulatory factors and the impact of observationally induced placebo and nocebo effects on treatment outcomes

Klauß, H., Kunkel, A., Müßgens, D., Haaker, J., & Bingel, U. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1293975 · Cited by 12

Conclusions Regarding the Role of Expectations in Placebo Analgesia Studies May Depend on How We Investigate It: A Meta-Analysis, Systematic Review, and Proposal for Methodological Discussions

Lunde, S. J., Rosenkjær, S., Matthiesen, S. T., Kirsch, I., & Vase, L. (2024) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001333 · Cited by 8

Patients’ Experiences During the Long Journey Before Initiating Migraine Prevention with a Calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibody (mAb)

Seng, E. K., Lampl, C., Viktrup, L., Lenderking, W. R., Karn, H., Hoyt, M. L., Kim, G., Ruff, D. D., Ossipov, M. H., & Vincent, M. B. (2024) · Pain and Therapy · doi:10.1007/s40122-024-00652-z · Cited by 9

Placeboeffekte in der Schmerztherapie

Kunkel, A., & Bingel, U. (2023) · Der Schmerz · doi:10.1007/s00482-022-00685-3 · Cited by 9

Expectation focused and frequency enhanced cognitive behavioural therapy for patients with major depression (EFFECT): a study protocol of a randomised active-control trial

Ewen, A.-C. I., Bleichhardt, G. M., Rief, W., von Blanckenburg, P., Wambach, K., & Wilhelm, M. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-065946 · Cited by 10

Increasing the Effectiveness of a Physical Activity Smartphone Intervention With Positive Suggestions: Randomized Controlled Trial

Skvortsova, A., Rodrigues, T. C., de Buisonjé, D. R., Kowatsch, T., Santhanam, P., Veldhuijzen, D. S., van Middendorp, H., & Evers, A. W. M. (2021) · Journal of Medical Internet Research · doi:10.2196/32130 · Cited by 11

Conscious connected breathing with breath retention intervention in adults with chronic low back pain: protocol for a randomized controlled pilot study

Pratscher, S. D., Sibille, K. T., & Fillingim, R. B. (2023) · Pilot and Feasibility Studies · doi:10.1186/s40814-023-01247-9 · Cited by 9

Positive Treatment Expectations Shape Perceived Medication Efficacy in a Translational Placebo Paradigm for the Gut-Brain Axis

Benson, S., Theysohn, N., Kleine‐Borgmann, J., Rebernik, L., Icenhour, A., & Elsenbruch, S. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.824468 · Cited by 7

Effects of a preoperative psychological expectation-focused intervention in patients undergoing valvular surgery - the randomized controlled ValvEx (valve patients’ expectations) study

Horn, N., Gärtner, L., Rastan, A. J., Andrási, T. B., Lenz, J., Böning, A., Salzmann-Djufri, M., Puvogel, U., Niemann, B., Genovese, M., et al. (2025) · American Heart Journal · doi:10.1016/j.ahj.2025.01.006 · Cited by 6

Nocebo effects are stronger and more persistent than placebo effects in healthy individualsPreprint

Kunkel, A., Schmidt, K., Hartmann, H., Strietzel, T., Sperzel, J.-L., Wiech, K., & Bingel, U. (2025) · eLife · doi:10.7554/elife.105753.3 · Cited by 9

Reframing pain: the power of individual and societal factors to enhance pain treatment

Slater, R., Eccleston, C., Williams, A. C. D. C., Vincent, K., Linde, M., Hurley, M., & Laughey, W. F. (2024) · PAIN Reports · doi:10.1097/pr9.0000000000001161 · Cited by 6

Dopamine has no direct causal role in the formation of treatment expectations and placebo analgesia in humans

Kunkel, A., Asan, L., Krüger, I., Erfurt, C., Ruhnau, L., Caliskan, E. B., Hackert, J., Wiech, K., Schmidt, K., & Bingel, U. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3002772 · Cited by 6

Placebo, nocebo: Believing in the field of medicine

Meißner, K. (2022) · Frontiers in Pain Research · doi:10.3389/fpain.2022.972169 · Cited by 7

Expectations and patient outcomes: a framework for intervention development in chronic pain management

Finan, P. H., & Colloca, L. (2025) · Pain · doi:10.1097/j.pain.0000000000003654 · Cited by 5

Influence of Role Expectancy on Patient-Reported Outcomes Among Patients With Migraine

May, A., Carvalho, G. F., Schwarz, A., & Basedau, H. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.3223 · Cited by 5

Neurobiologische und neurochemische Mechanismen der Placeboanalgesie

Asan, L., Bingel, U., & Kunkel, A. (2022) · Der Schmerz · doi:10.1007/s00482-022-00630-4 · Cited by 5

The role of the communicated treatment rationale on treatment outcome: study protocol for a randomized controlled trial

Henrich, L., Wilhelm, M., Lange, P., & Rief, W. (2023) · Trials · doi:10.1186/s13063-023-07557-w · Cited by 4

Ethical considerations with using placebo treatments and effects in clinical practice

Druart, L., Annoni, M., & Blease, C. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-29884-4.00008-x · Cited by 4

Associations Between Interindividual Differences, Expectations and Placebo and Nocebo Effects in Itch

Meeuwis, S. H., van Middendorp, H., Veldhuijzen, D. S., & Evers, A. W. M. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.781521 · Cited by 5

Temporal expectancy induced by the mere possession of a placebo analgesic affects placebo analgesia: preliminary findings from a randomized controlled trial

Yeung, V. W. L. (2022) · Scientific Reports · doi:10.1038/s41598-022-05537-9 · Cited by 3

Updating beliefs about pain following advice: Trustworthiness of social advice predicts pain expectations and experience

Krahé, C., Koukoutsakis, A., & Fotopoulou, A. (2024) · Cognition · doi:10.1016/j.cognition.2024.105756 · Cited by 4

Patient‐Reported Outcomes With Immediate‐Loaded Zygomatic Implant Fixed Rehabilitation in Patients With Edentulous Atrophic Maxilla: A Retrospective Practice‐Based Clinical Study

Rodrigues, A., Nader, S. A., Daniel, N. G., & Emami, E. (2025) · Clinical Oral Implants Research · doi:10.1111/clr.14432 · Cited by 3

The impact of patients' pre‐treatment expectations on immunosuppressive treatment outcomes in myasthenia gravis: A pilot correlational study

Frisaldi, E., Ferrero, B., Liberto, A. D., Barbiani, D., Camerone, E. M., Piedimonte, A., Vollert, J., Cavallo, R., Zibetti, M., Lopiano, L., et al. (2024) · Muscle & Nerve · doi:10.1002/mus.28189 · Cited by 3

Neural mechanisms underlying placebo and nocebo effects in tonic muscle pain

Chen, M., Wu, X. X., Zhang, L., Zhang, F., Li, L., Zhang, Y., Xiong, D., Qiu, Y., Hu, L., & Xiao, W. (2024) · NeuroImage · doi:10.1016/j.neuroimage.2024.120877 · Cited by 3

Generalization and enhancement of the effects of an active placebo nasal spray on sadness

Wilhelm, M., Fischer, S. M., Rief, W., Fiorio, M., & Barbiani, D. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.10.045 · Cited by 3

The effect of a methadone reformulation on opioid agonist treatment outcomes: A population-based study in British Columbia, Canada, 2013–14

Krebs, E., Hongdilokkul, N., Dale, L. M., Min, J. E., Schnepel, K., Shigeoka, H., & Nosyk, B. (2021) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2021.108714 · Cited by 3

Duloxetine in addition to self-management for painful temporomandibular disorders: a post hoc responder analysis of a randomized, placebo-controlled clinical trial

Ferreira, D. M. A. O., Soares, F. F. C., Raimundini, A. A., Bonjardim, L. R., Costa, Y. M., & Conti, P. C. R. (2024) · Journal of Applied Oral Science · doi:10.1590/1678-7757-2024-0035 · Cited by 2

Placebo and the doctor–patient interaction and communication

Evers, A. W. M., Broekman, F. L., Janine, W., Van Vliet Liesbeth, M., & H., M. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-29884-4.00015-7 · Cited by 2

Meta-Analysis of the Placebo Response in Chronic and Episodic Migraine: Insights from Migraine Preventive Drug Trials

Nookala, A. R., Panse, N., Gottipati, G., Fitter, H. D., Uppoor, R. S., Mehta, M., & Sabarinath, S. (2025) · The AAPS Journal · doi:10.1208/s12248-025-01181-z · Cited by 2

Placebo and nocebo in clinical practice: An online cross-sectional survey of healthcare professionals from European countries on views, practices and training needs

O’Keeffe, M., Skidmore, N., Bagnis, A., Bąbel, P., Bajcar, E. A., Palma, A. D., Evers, A. W. M., Glogan, E., Haas, J. W., Meeuwis, S. H., et al. (2026) · PLoS ONE · doi:10.1371/journal.pone.0338905 · Cited by 2

Symptom Perception and Interpretation

Gasteiger, C., & Petrie, K. J. (2021) · Comprehensive Clinical Psychology · doi:10.1016/b978-0-12-818697-8.00067-4 · Cited by 2

Study protocol: effects of treatment expectation toward repetitive transcranial magnetic stimulation (rTMS) in major depressive disorder—a randomized controlled clinical trial

Steiner, K. M., Timmann, D., Bingel, U., Kunkel, A., Spisák, T., Schedlowski, M., Benson, S., Engler, H., Scherbaum, N., & Koelkebeck, K. (2023) · Trials · doi:10.1186/s13063-023-07579-4 · Cited by 3

Alzheimer disease may compromise patients' ability for expectancy-based pain modulation. Now what?

Wiech, K., & Bingel, U. (2023) · Pain · doi:10.1097/j.pain.0000000000003036 · Cited by 2

Pain, mindfulness, and placebo: a systematic review

Lopes, A., Sampaio, R., & Tavares, I. (2024) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2024.1432270 · Cited by 2

Autonomic correlates of osteopathic manipulative treatment on facial functional mapping: an innovative approach based on thermal imaging

Cerritelli, F., Perpetuini, D., Keys, J., Merla, A., & Cardone, D. (2025) · Scientific Reports · doi:10.1038/s41598-025-92092-8 · Cited by 4

Expectations, conditioning, and the placebo effect do not differ between fibromyalgia patients and healthy controls but might be differently associated

Emergui, G., Agostinho, M. R., Canaipa, R., & Treister, R. (2025) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2025.112207 · Cited by 2

Seeing others is believing – Analgetische Placeboeffekte durch Beobachtungslernen?

Schwartz, M., Stuhlreyer, J., & Klinger, R. (2022) · Der Schmerz · doi:10.1007/s00482-022-00646-w · Cited by 2

Analgetische Placeboeffekte und Implikationen für die Behandlung chronischer Schmerzen

Schwartz, M., & Klinger, R. (2022) · Psychotherapeut · doi:10.1007/s00278-022-00592-z · Cited by 2

Erector spinae plane block: did low p values overstate the evidence against the null hypothesis and distract us from clinically unimportant effects?

Barrington, M. J. (2020) · Regional Anesthesia & Pain Medicine · doi:10.1136/rapm-2020-102152 · Cited by 2

Nocebo effects are stronger and more persistent than placebo effects in healthy individualsPreprint

Kunkel, A., Schmidt, K., Hartmann, H., Strietzel, T., Sperzel, J.-L., Wiech, K., & Bingel, U. (2025) · eLife · doi:10.7554/elife.105753.1 · Cited by 2

Revisiting the SSRI vs. placebo debate in the treatment of social anxiety disorder: the role of expectancy effects, neural responsivity, and monoamine transporters

Furmark, T., Wahlstedt, K., & Faria, V. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1531725 · Cited by 1

Inpatient’s, therapist’s and staff’s expectations regarding treatment and their effects on placebo response in the psychiatric ward – results from an add-on oxytocin RCT

Nitzan, U., Grossman‐Giron, A., Sedoff, O., Maoz, H., Arad, O., Tilbor, E., Dror, C., & Bitan, D. T. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06593-x · Cited by 1

The association between test anxiety, learning strategies, and open-label placebo effects on academic test performance: a secondary analysis of a randomized controlled trial

Frisaldi, E., Kleine‐Borgmann, J., Hartmann, H., Benson, S., Bingel, U., & Schmidt, K. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1529056 · Cited by 1

Placebo effects in mental disorders

Wilhelm, M., Rief, W., & Salzmann, S. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-29884-4.00016-9 · Cited by 1

Direct comparison of nocebo, deceptive placebo and open-label placebo effects on sustained visual attention

Potthoff, J., & Hartmann, H. (2025) · Acta Psychologica · doi:10.1016/j.actpsy.2025.106127 · Cited by 1

Variability of post-operative acute pain management and the association of patients' socio-demographics on pain management outcome in Indonesia: A multicenter hospital-based observational study

Laksono, R. M., Musba, A. M. T., Siswagama, T. A., Fitrisyah, A., Rofiq, A., Adithya, B., Wirabuana, B., Sutiyono, D., Adhiany, E., Purnomo, H. D., et al. (2026) · Dialogues in Health · doi:10.1016/j.dialog.2026.100300 · Cited by 1

Cognitive, Emotional, and Social Factors in the Modulation of Pain Perception

Илюшичев, В. Д., Dudkin, I. V., Mitiureva, D. G., Евгеньевич, М. П., Sysoeva, O. V., & Gerasimova, E. V. (2026) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-026-02005-z · Cited by 1

The Power of a Good Word: Enhancing the Efficacy of Analgesics in Clinical Settings

Treister, R., Cohen, V., Issa, L., Wiegler, K. B., Izakson, A., & Agostinho, M. R. (2024) · Psychotherapy and Psychosomatics · doi:10.1159/000541810 · Cited by 1

Shaping Treatment Expectation to Optimize Efficacy of Interleukin 17A Antagonist Secukinumab in Psoriasis Patients

Hölsken, S., Krefting, F., Mühlhaus, S., Bese, D., Schedlowski, M., & Sondermann, W. (2025) · Psoriasis Targets and Therapy · doi:10.2147/ptt.s486338 · Cited by 2

Topical preparations in the treatment of musculoskeletal pain

Tomašević-Todorović, S. (2022) · Galenika Medical Journal · doi:10.5937/galmed2201088t · Cited by 1

Movement-related pain as a learned response: an investigation of the possible mechanisms underlyng movement-related pain persistence and recovery in subjects with chronic musculoskeletal pain

Alaiti, R. K. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.47.2021.tde-01102021-162436 · Cited by 1

Patient Expectancy Does Not Predict Success or Failure of Thermal Neurotomy for Persistent Zygapophysial and Sacroiliac Joint Pain

Speldewinde, G. C., & Panwar, C. E. (2021) · Pain Medicine · doi:10.1093/pm/pnab133

An introduction to the Biennial Review of Pain

Rice, A. S. C., & Keefe, F. J. (2020) · Pain · doi:10.1097/j.pain.0000000000001979

Efeitos de estímulos verbais na dor

Sousa, P. T. A. (2022) · doi:10.11606/d.47.2022.tde-20062022-144358

Expectations

Lunde, S. J., Kirsch, I., Bingel, U., Büchel, C., & Vase, L. (2023) · Oxford University Press eBooks · doi:10.1093/med/9780197645444.003.0002

Placebo–Placebo, Nocebo–Nocebo, Placebo–Nocebo, and Nocebo–Placebo Effects: A Review of Eastern and Western PerspectivesPreprint

JARALI, S. S. (2024) · PsyArXiv (OSF Preprints) · doi:10.31234/osf.io/f6nrz

Placebo in Sports Medicine Research

Prill, R., Ostojić, M., & Królikowska, A. (2024) · Springer eBooks · doi:10.1007/978-3-642-36801-1_500-1

Interdisciplinary pain program participants with high catastrophizing scores improve function utilizing enriched therapeutic encounters and integrative health techniques: a retrospective study

Vora, A. J., Kennedy-Spaien, E., Gray, S., Estudillo‐Guerra, M. A., Phillips, G., Mesia-Toledo, I., Glenn, M. B., Chin, B. S., & Morales-Quezada, L. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1448117 · Cited by 3

Die Bedeutung von Placebomechanismen in der Schmerztherapie

Bingel, U. (2024) · Elsevier eBooks · doi:10.1016/b978-3-437-21545-2.00022-7

Placebo in Sports Medicine Research

Prill, R., Ostojić, M., & Królikowska, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-58351-3_500

Nocebo effects are stronger and more persistent than placebo effects in healthy individualsPreprint

Kunkel, A., Schmidt, K., Hartmann, H., Strietzel, T., Sperzel, J.-L., Wiech, K., & Bingel, U. (2025) · eLife · doi:10.7554/elife.105753.2

Modulating Placebo Effects in Clinical Trials: Study Team Briefing to Optimize Drug–Placebo Differences

Coenen, M., Bingel, U., Berdaguer, M. S., Fuhrmann, C., Németh, R., Rengelshausen, J., Hartmann, G., Coch, C., & Schedlowski, M. (2025) · Clinical and Translational Science · doi:10.1111/cts.70399

The effect of physiotherapists' explanation of therapeutic virtual reality on treatment expectations in healthy people and people with chronic musculoskeletal pain: Two online RCTs

Slatman, S., van Lankveld, W., Staal, J. B., van Goor, H., Ostelo, R., Westendorp, J., & Knoop, J. (2025) · PEC Innovation · doi:10.1016/j.pecinn.2025.100443

The first consultation of a patient with chronic pelvic pain

Messelink, B. (2026) · Continence Reports · doi:10.1016/j.contre.2026.100108

The power to adapt: How resilience and changing expectations contribute to placebo effects

Thomas, S., Resnick, B. M., Klinedinst, N. J., Zhu, S., & Colloca, L. (2026) · Journal of Pain · doi:10.1016/j.jpain.2026.106234 · Cited by 1

Expectations are associated with psychological and biological outcomes after allogeneic hematopoietic stem cell transplantation in a prospective cohort study

Salzmann, S., Euteneuer, F., Lishewski, P., Trenker, C., Schäfer, J., Mack, E., Sohlbach, K., Neubauer, A., Beilharz, L., Rief, W., et al. (2026) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2026.112640

An eight-week placebo-controlled RCT on the efficacy of a probiotic nutritional intervention for subclinical gastrointestinal symptoms in students

Winkler, A., Hermann, C., Hahn, A., & Beis, D. M. (2026) · Scientific Reports · doi:10.1038/s41598-026-44433-4

What people want to know before surgery – The role of sex and expectation

Horn, N., Gärtner, L., Rief, W., & Salzmann, S. (2026) · Patient Education and Counseling · doi:10.1016/j.pec.2026.109599

Longitudinal assessment and clinical implications of treatment expectations in an outpatient pain centre: evaluation of the GEEE in patients with chronic pain

Henrich, L., Basedow, L. A., Maser, D., Schmidt, K., Bingel, U., & Rief, W. (2026) · BMJ Open · doi:10.1136/bmjopen-2024-097959

Placebo analgesia : the role of expectation and aversive prediction error

Hird, E. (2018) · Research Explorer (The University of Manchester) · Cited by 1

Placebo analgesia: Psycho-neuro-physiological interactions and clinical implications

Vase, L. (2007)

Placebo analgesia: Clinical applications

Klinger, R., Colloca, L., Bingel, U., & Flor, H. (2013) · Pain · doi:10.1016/j.pain.2013.12.007 · Cited by 99

[Placebo analgesia].

Bingel, U. (2014) · PubMed

CLINICIANS' EXPECTATIONS INFLUENCE PLACEBO ANALGESIA

Gracely, R. H., Dubner, R. A., Deeter, W. R., & Wolskee, P. J. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90984-5 · Cited by 311