Intraductal Papillary Mucinous Neoplasm of the Pancreas as the Main Focus for Early Detection of Pancreatic Adenocarcinoma
Abstract
For early detection of pancreatic cancer, interests are now focused on the detection of high-risk individuals to undergo screening examinations. Intraductal papillary mucinous neoplasm (IPMN) is a unique dual precursor of pancreatic cancer, characterized by progression to invasive cancer and the development of pancreatic adenocarcinoma either concomitantly (synchronous occurrence) or even after resection of IPMN (metachronous occurrence). Careful examination and surveillance of patients with IPMN may therefore lead to early detection of pancreatic cancer. By reviewing only reports describing detailed breakdown of the morphological types of IPMN and numbers of patients with noninvasive and invasive carcinoma in each type, the rough frequencies of noninvasive carcinoma in main duct IPMNs and branch duct IPMNs (BD-IPMNs) are 20% and 10%, respectively, and those of invasive carcinoma are 40% and 13%, respectively. Roughly 5% of all patients with IPMN had concomitant adenocarcinoma. The real frequency of carcinoma in BD-IPMNs would be far lower because most patients with small asymptomatic BD-IPMNs do not undergo resection. Intraductal papillary mucinous neoplasm can be the main focus for early detection of pancreatic cancer to achieve favorable prognosis after surgical resection. The optimal protocol for surveillance and method for early detection of pancreatic cancer are to be determined.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
It is estimated that 5% of patients with IPMNs have concomitant adenocarcinoma elsewhere in the pancreas.
“Conversely, a negative biopsy or cytology does not rule out the presence of a high-risk lesion, and it is estimated that 5% of patients with IPMNs have concomitant adenocarcinoma elsewhere in the pancreas [18,19].”
From Artificial Intelligence in the Diagnosis and Treatment of Pancreatic Cystic Lesions and Adenocarcinoma (2023) · cites this paper as [18]
Cites
Jemal, A., Siegel, R. L., Ward, E. M., Murray, T., Xu, J., Smigal, C., & Thun, M. J. (2006) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.56.2.106 · Cited by 5,309 · see citing works
International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas
Tanaka, M., Fernández-del Castillo, C., Adsay, V., Chari, S., Falconi, M., Jang, J.-Y., Kimura, W., Levy, P., Pitman, M. B., Schmidt, C. M., et al. (2012) · Pancreatology · doi:10.1016/j.pan.2012.04.004 · Cited by 2,354 · see citing works
Self-citationTanaka, M., Chari, S. T., Adsay, V. N., Carlos, F.-D., Falconi, M., Shimizu, M., Yamaguchi, K., Yamao, K., & Matsuno, S. (2005) · Pancreatology · doi:10.1159/000090023 · Cited by 2,042 · see citing works
Self-citationSalvia, R., Castillo, C., Bassi, C., Thayer, S., Falconi, M., Mantovani, W., Pederzoli, P., & Warshaw, A. (2004) · Annals of Surgery · doi:10.1097/01.sla.0000124386.54496.15 · Cited by 783 · see citing works
Rodríguez, J. R., Salvia, R., Crippa, S., Warshaw, A. L., Bassi, C., Falconi, M., Thayer, S. P., Lauwers, G. Y., Capelli, P., Mino-Kenudson, M. A., et al. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.05.010 · Cited by 437 · see citing works
Predictive factors for malignancy in intraductal papillary–mucinous tumours of the pancreas
Sugiyama, M., Izumisato, Y., Abe, N., Masaki, T., Mori, T., & Atomi, Y. (2003) · British journal of surgery · doi:10.1002/bjs.4265 · Cited by 427 · see citing works
Terris, B., Ponsot, P., Paye, F., Hammel, P. R., Sauvanet, A., Molas, G., Bernades, P., Belghiti, J., Ruszniewski, P. B., & Fléjou, J. (2000) · The American Journal of Surgical Pathology · doi:10.1097/00000478-200010000-00006 · Cited by 418 · see citing works
Intraductal Papillary Mucinous Neoplasms
Schmidt, C. M., White, P. B., Waters, J. A., Yiannoutsos, C. T., Cummings, O. W., Baker, M. S., Howard, T. J., Zyromski, N. J., Nakeeb, A., DeWitt, J. M., et al. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e318155a9e5 · Cited by 413 · see citing works
Intraductal Papillary Mucinous Tumors of the Pancreas Comprise 2 Clinical Subtypes
Kobari, M. (1999) · Archives of Surgery · doi:10.1001/archsurg.134.10.1131 · Cited by 323 · see citing works
Crippa, S., Castillo, C. F. F.-D., Salvia, R., Finkelstein, D. M., Bassi, C., Domínguez, I., Muzikansky, A., Thayer, S. P., Falconi, M., Mino-Kenudson, M. A., et al. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.10.001 · Cited by 322 · see citing works
Uehara, H., Nakaizumi, A., Ishikawa, O., Iishi, H., Tatsumi, K., Takakura, R., Ishida, T., Takano, Y., Tanaka, S., & Takenaka, A. (2008) · Gut · doi:10.1136/gut.2007.145631 · Cited by 286 · see citing works
Sahora, K., Mino-Kenudson, M., Brugge, W., Thayer, S. P., Ferrone, C. R., Sahani, D., Pitman, M. B., Warshaw, A. L., Lillemoe, K. D., & Fernandez-del Castillo, C. F. (2013) · Annals of Surgery · doi:10.1097/sla.0b013e3182a18f48 · Cited by 285 · see citing works
Pergolini, I., Sahora, K., Ferrone, C. R., Morales‐Oyarvide, V., Wolpin, B. M., Mucci, L. A., Brugge, W. R., Mino-Kenudson, M. A., Patiño, M., Sahani, D. V., et al. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.07.019 · Cited by 280 · see citing works
Yamaguchi, K., Ohuchida, J., Ohtsuka, T., Nakano, K., & Tanaka, M. (2002) · Pancreatology (Print) · doi:10.1159/000064716 · Cited by 243 · see citing works
Self-citationNatural History of Branch Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas
Maguchi, H., Tanno, S., Mizuno, N., Hanada, K., Kobayashi, G., Hatori, T., Sadakari, Y., Yamaguchi, T., Tobita, K., Doi, R., et al. (2011) · Pancreas · doi:10.1097/mpa.0b013e31820a5975 · Cited by 226 · see citing works
Self-citationPancreatic Cancer in Patients With Pancreatic Cystic Lesions: A Prospective Study in 197 Patients
Tada, M., Kawabe, T., Arizumi, M., Togawa, O., Matsubara, S., Yamamoto, N., Nakai, Y., Sasahira, N., Hirano, K., Tsujino, T., et al. (2006) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.07.013 · Cited by 206 · see citing works
Intraductal Papillary Mucinous Neoplasms of the Pancreas
Ohno, E., Hirooka, Y., Ito, A., Ishigami, M., Katano, Y., Ohmiya, N., Niwa, Y., & Goto, H. (2009) · Annals of Surgery · doi:10.1097/sla.0b013e3181a189a8 · Cited by 199 · see citing works
Anand, N., Sampath, K., & Wu, B. U. (2013) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2013.02.010 · Cited by 195 · see citing works
Ingkakul, T., Sadakari, Y., Ienaga, J., Satoh, N., Takahata, S., & Tanaka, M. (2009) · Annals of Surgery · doi:10.1097/sla.0b013e3181c5ddc3 · Cited by 190 · see citing works
Self-citationJang, J.-Y., Kim, S.-W., Lee, S. E., Yang, S. H., Lee, K., Lee, Y. J., Kim, S.-C., Han, D., Choi, D., Choi, S., et al. (2007) · Annals of Surgical Oncology · doi:10.1245/s10434-007-9603-5 · Cited by 175 · see citing works
Tanno, S., Nakano, Y., Koizumi, K., Sugiyama, Y., Nakamura, K., Sasajima, J., Nishikawa, T., Mizukami, Y., Yanagawa, N., Fujii, T., et al. (2009) · Pancreas · doi:10.1097/mpa.0b013e3181b91cd0 · Cited by 163 · see citing works
He, J. P., Cameron, J. L., Ahuja, N., Makary, M. A., Hirose, K., Choti, M. A., Schulick, R. D., Hruban, R. H., Pawlik, T. M., & Wolfgang, C. L. (2013) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2012.12.026 · Cited by 163 · see citing works
Kitagawa, Y., Unger, T. A., Taylor, S. L., Kozarek, R. A., & Traverso, L. W. (2003) · Journal of Gastrointestinal Surgery · doi:10.1016/s1091-255x(02)00152-x · Cited by 155 · see citing works
Kamata, K., Kitano, M., Kudo, M., Sakamoto, H., Kadosaka, K., Miyata, T., Imai, H., Maekawa, K., Chikugo, T., Kumano, M., et al. (2013) · Endoscopy · doi:10.1055/s-0033-1353603 · Cited by 148 · see citing works
Sadakari, Y., Ienaga, J., Kobayashi, K., Miyasaka, Y., Takahata, S., Nakamura, M., Mizumoto, K., & Tanaka, M. (2010) · Pancreas · doi:10.1097/mpa.0b013e3181bab60e · Cited by 147 · see citing works
Self-citationTanno, S., Nakano, Y., Sugiyam, Y., Nakamura, K., Sasajima, J., Koizumi, K., Yamazaki, M., Nishikawa, T., Mizukami, Y., Yanagawa, N., et al. (2010) · Pancreatology · doi:10.1159/000231982 · Cited by 144 · see citing works
Nagai, K., Doi, R., Kida, A., Kami, K., Kawaguchi, Y., Ito, T., Sakurai, T., & Üemoto, S. (2007) · World Journal of Surgery · doi:10.1007/s00268-007-9281-2 · Cited by 138 · see citing works
Han, Y., Lee, H., Kang, J. S., Kim, J. R., Kim, H. S., Lee, J. M., Lee, K.-B., Kwon, W., Kim, S., & Jang, J. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.10.013 · Cited by 130 · see citing works
Patterns of Recurrence After Resection of IPMN
Marchegiani, G., Mino-Kenudson, M. A., Ferrone, C. R., Morales‐Oyarvide, V., Warshaw, A. L., Lillemoe, K. D., & Castillo, C. F. F.-D. (2015) · Annals of Surgery · doi:10.1097/sla.0000000000001008 · Cited by 128 · see citing works
Hwang, D., Jang, J.-Y., Lee, S. E., Lim, C., Lee, K., & Kim, S.-W. (2010) · Langenbeck's archives of surgery (Print) · doi:10.1007/s00423-010-0674-6 · Cited by 123 · see citing works
LaFemina, J., Katabi, N., Klimstra, D., Correa-Gallego, C., Gaujoux, S., Kingham, T., DeMatteo, R., Fong, Y., D'Angelica, M., Jarnagin, W., et al. (2013) · Annals of Surgical Oncology · doi:10.1245/s10434-012-2702-y · Cited by 113 · see citing works
Khannoussi, W., Vullierme, M., Rebours, V., Maire, F., Hentic, O., Aubert, A., Sauvanet, A., Dokmak, S., Couvelard, A., Hammel, P. R., et al. (2012) · Pancreatology · doi:10.1016/j.pan.2012.03.056 · Cited by 109 · see citing works
Kanno, A., Satoh, K., Hirota, M., Hamada, S., Umino, J., Itoh, H., Masamune, A., Asakura, T., & Shimosegawa, T. (2010) · Journal of Gastroenterology · doi:10.1007/s00535-010-0238-0 · Cited by 99 · see citing works
Ohtsuka, T., Kono, H., Tanabe, R., Nagayoshi, Y., Mori, Y., Sadakari, Y., Takahata, S., Oda, Y., Aishima, S., Igarashi, H., et al. (2011) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2011.04.007 · Cited by 98 · see citing works
Self-citationManagement of Intraductal Papillary-mucinous Neoplasm of the Pancreas
Serikawa, M., Sasaki, T., Fujimoto, Y., Kuwahara, K., & Chayama, K. (2006) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000225609.63975.6f · Cited by 97 · see citing works
Controversies in the management of pancreatic IPMN
Tanaka, M. (2011) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2010.193 · Cited by 94 · see citing works
Self-citationCorrea‐Gallego, C., Do, R., LaFemina, J., Gönen, M., D'Angelica, M. I., DeMatteo, R. P., Fong, Y., Kingham, T. P., Brennan, M. F., Jarnagin, W. R., et al. (2013) · Annals of Surgical Oncology · doi:10.1245/s10434-013-3207-z · Cited by 93 · see citing works
Kim, S. C., Park, K. T., Lee, Y. J., Lee, S. S., Seo, D. W., Lee, S. K., Kim, M. H., Jang, S. J., Byun, J. H., & Han, D. J. (2008) · Journal of Hepato-Biliary-Pancreatic Surgery · doi:10.1007/s00534-007-1231-8 · Cited by 85 · see citing works
Nara, S., Onaya, H., Hiraoka, N., Shimada, K., Sano, T., Sakamoto, Y., Esaki, M., & Kosuge, T. (2008) · Pancreas · doi:10.1097/mpa.0b013e318181b90d · Cited by 84 · see citing works
Sahora, K., Castillo, C. F. F.-D., Dong, F., Marchegiani, G., Thayer, S. P., Ferrone, C. R., Sahani, D. V., Brugge, W. R., Warshaw, A. L., Lillemoe, K. D., et al. (2014) · Surgery · doi:10.1016/j.surg.2014.04.023 · Cited by 83 · see citing works
Predictors of Malignant Intraductal Papillary Mucinous Neoplasm of the Pancreas
Mimura, T., Masuda, A., Matsumoto, I., Shiomi, H., Yoshida, S., Sugimoto, M., Sanuki, T., Yoshida, M., Fujita, T., Kutsumi, H., et al. (2010) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e3181d8fb91 · Cited by 80 · see citing works
Aso, T., Ohtsuka, T., Matsunaga, T., Kimura, H., Watanabe, Y., Tamura, K., Ideno, N., Osoegawa, T., Takahata, S., Shindo, K., et al. (2014) · Pancreas · doi:10.1097/mpa.0000000000000199 · Cited by 80 · see citing works
Self-citationUehara, H., Ishikawa, O., Katayama, K., Kawada, N., Ikezawa, K., Fukutake, N., Takakura, R., Takano, Y., Tanaka, S., & Takenaka, A. (2010) · Journal of Gastroenterology · doi:10.1007/s00535-010-0343-0 · Cited by 80 · see citing works
Miyasaka, Y., Ohtsuka, T., Tamura, K., Mori, Y., Shindo, K., Yamada, D., Takahata, S., Ishigami, K., Ito, T., Tokunaga, S., et al. (2015) · Annals of Surgery · doi:10.1097/sla.0000000000001368 · Cited by 76 · see citing works
Self-citationNakata, K., Ohuchida, K., Aishima, S., Sadakari, Y., Kayashima, T., Miyasaka, Y., Nagai, E., Mizumoto, K., Tanaka, M., Tsuneyoshi, M., et al. (2011) · Pancreas · doi:10.1097/mpa.0b013e318214fa86 · Cited by 73 · see citing works
Self-citationCrippa, S., Pergolini, I., Rubini, C., Castelli, P., Partelli, S., Zardini, C., Marchesini, G., Zamboni, G., & Falconi, M. (2015) · Surgery · doi:10.1016/j.surg.2015.11.003 · Cited by 64 · see citing works
Hirono, S. (2009) · Archives of Surgery · doi:10.1001/archsurg.2009.2 · Cited by 61 · see citing works
Pedrazzoli, S., Sperti, C., Pasquali, C., Bissoli, S., & Chierichetti, F. (2011) · Annals of Surgery · doi:10.1097/sla.0b013e3182383137 · Cited by 54 · see citing works
Gian, R. K., Katz, S. S., Gollub, M. J., Li, J., LaFemina, J., Zabor, E. C., Moskowitz, C. S., Klimstra, D. S., & Allen, P. J. (2014) · American Journal of Roentgenology · doi:10.2214/ajr.13.11490 · Cited by 52 · see citing works
Pancreatic cyst as a sentinel ofin situ carcinoma of the pancreas
Yamaguchi, K., Nakamura, K., Yokohata, K., Shimizu, S., Chijiiwa, K., & Tanaka, M. (1997) · International Journal of Pancreatology · doi:10.1007/bf02788389 · Cited by 51 · see citing works
Self-citationLong‐term follow up results of intraductal papillary mucinous tumors of pancreas
Lee, S., Lee, K. T., Lee, J. K., Jeon, Y. H., Choi, D., Lim, J. H., Heo, J. S., Choi, S. H., Jang, K., Paik, S. W., et al. (2005) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2005.04014.x · Cited by 50 · see citing works
Barron, M. R., Roch, A. M., Waters, J. A., Parikh, J. A., DeWitt, J. M., Al‐Haddad, M., Ceppa, E. P., House, M. G., Zyromski, N. J., Nakeeb, A., et al. (2014) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-013-2444-6 · Cited by 48 · see citing works
Bournet, B., Kirzin, S., Carrère, N., Portier, G., Otal, P., Sèlves, J., Musso, C., Suc, B., Moreau, J., Fourtanier, G., et al. (2009) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2009.05826.x · Cited by 46 · see citing works
Tanaka, M. (2014) · Digestion · doi:10.1159/000370111 · Cited by 43 · see citing works
Self-citationPrognosis of cancer with branch duct type IPMN of the pancreas
Ikeuchi, N. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i15.1890 · Cited by 42 · see citing works
Pérez‐Cuadrado‐Robles, E., Maire, F., Cros, J. F., Vullierme, M., Rebours, V., Sauvanet, A., Aubert, A., Dokmak, S., Lévy, P., & Ruszniewski, P. B. (2016) · United European Gastroenterology Journal · doi:10.1177/2050640615623370 · Cited by 41 · see citing works
Hwang, D. W., Jang, J., Lim, C.-S., Lee, S. E., Yoon, Y., Ahn, Y. J., Han, H., Kim, S., Kim, S. G., Yun, Y. K., et al. (2011) · Journal of Korean Medical Science · doi:10.3346/jkms.2011.26.6.740 · Cited by 37 · see citing works
Ohtsuka, T., Ideno, N., Aso, T., Nagayoshi, Y., Kono, H., Mori, Y., Takahata, S., Oda, Y., Aishima, S., Igarashi, H., et al. (2012) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1007/s00534-012-0541-7 · Cited by 34 · see citing works
Self-citationMori, Y., Ohtsuka, T., Tsutsumi, K., Yasui, T., Sadakari, Y., Ueda, J., Takahata, S., Nakamura, M., & Tanaka, M. (2015) · PubMed · doi:10.6092/1590-8577/3628 · Cited by 32 · see citing works
Self-citationSegmental balloon cytology for preoperative localization of in situ pancreatic cancer
Tanaka, M., Yokohata, K., Konomi, H., Yamaguchi, K., Chijiiwa, K., & Ohta, M. (1997) · Gastrointestinal Endoscopy · doi:10.1016/s0016-5107(97)70039-7 · Cited by 32 · see citing works
Self-citationTanaka, M. (2015) · Digestive Endoscopy · doi:10.1111/den.12434 · Cited by 25 · see citing works
Self-citationTamura, K., Ohtsuka, T., Ideno, N., Aso, T., Kono, H., Nagayoshi, Y., Shindo, K., Ushijima, Y., Ueda, J., Takahata, S., et al. (2013) · PubMed · doi:10.6092/1590-8577/1494 · Cited by 20 · see citing works
Self-citationMoriya, T., Hashimoto, Y., & Traverso, L. W. (2011) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-011-1437-6 · Cited by 20 · see citing works
Sakamoto, H., Kitano, M., Komaki, T., Imai, H., Kamata, K., Kimura, M., Takeyama, Y., & Kudo, M. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.5489 · Cited by 19 · see citing works
Law, J. K., Wolfgang, C. L., Weiss, M. J., & Lennon, A. M. (2014) · PubMed Central · doi:10.3748/wjg.v20.i27.9200 · Cited by 14 · see citing works
Jarry, J., Belleannée, G., Rault, A., Cunha, A. S., & Collet, D. (2016) · PubMed · doi:10.6092/1590-8577/3872 · Cited by 7 · see citing works
Intraductal papillary mucinous neoplasms of the pancreas--predictors of malignancy.
Fan, F., Lai, E. C. H., Xie, F., Yang, J., Xu, F., Kan, T., Shen, R.-X., Yang, X., Wan, Y. L., & Wu, M.-C. (2010) · PubMed · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Early Detection of Pancreatic Cancer: Opportunities and Challenges
Singhi, A. D., Koay, E. J., Chari, S. T., & Maitra, A. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.01.259 · Cited by 841 · see citing works
Ohtsuka, T., Castillo, C. F. F.-D., Furukawa, T., Hijioka, S., Jang, J., Lennon, A. M., Miyasaka, Y., Ohno, E., Salvia, R., Wolfgang, C. L., et al. (2023) · Pancreatology · doi:10.1016/j.pan.2023.12.009 · Cited by 549 · see citing works
Early detection of pancreatic cancer using DNA-based molecular approaches
Singhi, A. D., & Wood, L. D. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00470-0 · Cited by 127 · see citing works
Pancreatic Cystic Lesions and Malignancy: Assessment, Guidelines, and the Field Defect
Miller, F. H., Vendrami, C. L., Recht, H. S., Wood, C. G., Mittal, P., Keswani, R. N., Gabriel, H. A., Borhani, A. A., Nikolaidis, P., & Hammond, N. A. (2021) · Radiographics · doi:10.1148/rg.210056 · Cited by 99 · see citing works
Skaro, M. F., Nanda, N., Gauthier, C. D., Felsenstein, M., Jiang, Z., Qiu, M., Shindo, K., Yu, J., Hutchings, D., Javed, A. A., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.01.254 · Cited by 65 · see citing works
Marchegiani, G., Pollini, T., Andrianello, S., Tomasoni, G., Biancotto, M., Javed, A. A., Kinny-Köster, B., Amini, N., Han, Y., Kim, H., et al. (2021) · JAMA Surgery · doi:10.1001/jamasurg.2021.1802 · Cited by 63 · see citing works
Elevating pancreatic cystic lesion stratification: Current and future pancreatic cancer biomarker(s)
Carmicheal, J., Patel, A., Dalal, V., Atri, P., Dhaliwal, A., Wittel, U. A., Malafa, M. P., Talmon, G. A., Swanson, B. J., Singh, S., et al. (2019) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2019.188318 · Cited by 55 · see citing works
Advances in Early Detection of Pancreatic Cancer
Kanno, A., Masamune, A., Hanada, K., Kikuyama, M., & Kitano, M. (2019) · Diagnostics · doi:10.3390/diagnostics9010018 · Cited by 56 · see citing works
Excellent Accuracy of Glucose Level in Cystic Fluid for Diagnosis of Pancreatic Mucinous Cysts
Faias, S. R., Pereira, L. C., Roque, R. R., Chaves, P. P., Torres, J., Cravo, M. L., & Pereira, A. D. (2019) · Digestive Diseases and Sciences · doi:10.1007/s10620-019-05936-5 · Cited by 45 · see citing works
Pollini, T., Adsay, V., Capurso, G., Molin, M. D., Esposito, I., Hruban, R. H., Luchini, C., Maggino, L., Matthaei, H., Marchegiani, G., et al. (2022) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(22)00235-7 · Cited by 40 · see citing works
Early detection of pancreatic cancer
Garg, S. K., & Chari, S. T. (2020) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000663 · Cited by 39 · see citing works
Jiang, J., Chao, W.-L., Culp, S., & Krishna, S. G. (2023) · Cancers · doi:10.3390/cancers15092410 · Cited by 38 · see citing works
Riva, G., Pea, A., Pilati, C., Fiadone, G., Lawlor, R. T., Scarpa, A., & Luchini, C. (2018) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v10.i10.317 · Cited by 34 · see citing works
From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer
Bazzichetto, C., Conciatori, F., Luchini, C., Simionato, F., Santoro, R., Vaccaro, V., Corbo, V., Falcone, I., Ferretti, G., Cognetti, F., et al. (2020) · Cells · doi:10.3390/cells9020309 · Cited by 33 · see citing works
Ohtsuka, T., Maguchi, H., Tokunaga, S., Hijioka, S., Takayama, Y., Koshita, S., Hanada, K., Sudo, K., Uehara, H., Tanno, S., et al. (2024) · Pancreatology · doi:10.1016/j.pan.2024.08.013 · Cited by 33 · see citing works
Self-citationPaolino, G., Esposito, I., Hong, S., Baştürk, O., Mattiolo, P., Kaneko, T., Veronese, N., Scarpa, A., Adsay, V. N., & Luchini, C. (2022) · Histopathology · doi:10.1111/his.14698 · Cited by 34 · see citing works
Harnessing Analytic Morphomics for Early Detection of Pancreatic Cancer
Petrov, M. S. (2018) · Pancreas · doi:10.1097/mpa.0000000000001155 · Cited by 30 · see citing works
Kane, L. E., Mellotte, G. S., Conlon, K. C., Ryan, B. M., & Maher, S. G. (2021) · Cancers · doi:10.3390/cancers13040769 · Cited by 27 · see citing works
Yoshioka, T., Shigekawa, M., Ikezawa, K., Tamura, T., Sato, K., Urabe, M., Sueyoshi, H., Yamai, T., Suda, T., Sakamori, R., et al. (2020) · Pancreas · doi:10.1097/mpa.0000000000001521 · Cited by 25 · see citing works
Tanaka, S., Tsujimae, M., Masuda, A., Inoue, J., Inomata, N., Uemura, H., Kohashi, S., Nagao, K., Masuda, S., Abe, S., et al. (2023) · Pancreas · doi:10.1097/mpa.0000000000002267 · Cited by 24 · see citing works
Early detection of pancreatic cancer: current state and future opportunities
Trikudanathan, G., Lou, E., Maitra, A., & Majumder, S. (2021) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000770 · Cited by 23 · see citing works
Paolino, G., Baştürk, O., Esposito, I., Hong, S., Brosens, L. A. A., Tarcan, Z. C., Wood, L. D., Γκουντάκος, Α., Omori, Y., Mattiolo, P., et al. (2024) · Modern Pathology · doi:10.1016/j.modpat.2024.100554 · Cited by 22 · see citing works
Intraductal Papillary Mucinous Neoplasms in Hereditary Cancer Syndromes
Ardeshna, D. R., Rangwani, S. M., Cao, T., Pawlik, T. M., Stanich, P. P., & Krishna, S. G. (2022) · Biomedicines · doi:10.3390/biomedicines10071475 · Cited by 22 · see citing works
Turner, R. C., Melnychuk, J., Chen, W., Jones, D. B., & Krishna, S. G. (2022) · Diagnostics · doi:10.3390/diagnostics12112573 · Cited by 21 · see citing works
Pancreatic Cancer: A Review of Risk Factors
Grigorescu, R. R., Husar-Sburlan, I. A., & Gheorghe, C. (2024) · Life · doi:10.3390/life14080980 · Cited by 21 · see citing works
Guzmán‐Calderón, E., Martínez‐Moreno, B., Casellas, J. A., & Aparicio, J. R. (2021) · Digestive Diseases and Sciences · doi:10.1007/s10620-021-07035-w · Cited by 20 · see citing works
Felix, K., Honda, K., Nagashima, K., Kashiro, A., Takeuchi, K., Kobayashi, T., Hinterkopf, S., Gaida, M. M., Dang, H. T., Brindl, N., et al. (2021) · International Journal of Cancer · doi:10.1002/ijc.33875 · Cited by 20 · see citing works
Pancreatic Cyst Surveillance: Who, Why, How?
Luk, L., Lowy, A. M., Li, K. D., Fowler, K. J., Wang, Z. J., Kamel, I. R., & Liau, J. (2023) · Radiology · doi:10.1148/radiol.222778 · Cited by 18 · see citing works
Intraductal papillary mucinous neoplasms of the pancreas: a clinical challenge
Rossi, R. E., & Massironi, S. (2018) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2018.1530111 · Cited by 17 · see citing works
Pergolini, I., Jäger, C., Safak, O., Göß, R., Novotny, A., Ceyhan, G. O., Frieß, H., & Demir, İ. E. (2020) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2020.04.090 · Cited by 16 · see citing works
Lee, D. Y., Shin, J., Kim, S., Baek, S., Lee, S., Son, N., & Park, M. (2023) · European Radiology · doi:10.1007/s00330-023-10158-5 · Cited by 15 · see citing works
Multi-omic markers of intraductal papillary mucinous neoplasms progression into pancreatic cancer
Corradi, C., Gentiluomo, M., Adsay, V. N., Sáinz, J., Camisa, P. R., Włodarczyk, B., Crippa, S., Tavano, F., Capurso, G., & Campa, D. (2024) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2024.12.005 · Cited by 12 · see citing works
Huang, X., Zhang, B., Zhao, J., Sun, C., Kong, K., Deng, L., Liu, Y., & Zheng, J. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00610 · Cited by 11 · see citing works
Integrating Molecular Analysis into the Pathologic Evaluation of Pancreatic Cysts
Bell, P. D., & Singhi, A. D. (2022) · Surgical pathology clinics · doi:10.1016/j.path.2022.05.009 · Cited by 10 · see citing works
Oi, H., Hozaka, Y., Akahane, T., Fukuda, K., Idichi, T., Tanoue, K., Yamasaki, Y., Kawasaki, Y., Mataki, Y., Kurahara, H., et al. (2024) · Pancreas · doi:10.1097/mpa.0000000000002373 · Cited by 9 · see citing works
Zhu, Z., Liu, J., Hong, C. W., Houshmand, S., Wang, K., & Yang, Y. (2025) · American Journal of Roentgenology · doi:10.2214/ajr.25.32729 · Cited by 9 · see citing works
Jiang, J. H., Chao, W., Cao, T., Culp, S., Napoléon, B., El-Dika, S. S., Machicado, J. D., Pannala, R., Mok, S. R. S., Luthra, A., et al. (2023) · Biomimetics · doi:10.3390/biomimetics8060496 · Cited by 9 · see citing works
Huang, C., Prabhu, V., Smereka, P. N., Vij, A., Anthopolos, R., Hajdu, C. H., & Dane, B. R. (2024) · Abdominal Radiology · doi:10.1007/s00261-024-04449-8 · Cited by 8 · see citing works
Early Detection of Pancreatic Cancer: Risk Factors and the Current State of Screening Modalities.
Keihanian, T., Barkin, J. A., & Souto, E. O. (2021) · PubMed Central · Cited by 7 · see citing works
Yoshioka, T., Shigekawa, M., Ikezawa, K., Hirao, M., Ishii, S., Suda, T., Kegasawa, T., Matsumoto, K., Iwahashi, K., Murata, J., et al. (2023) · Pancreatology · doi:10.1016/j.pan.2023.11.005 · Cited by 7 · see citing works
Translation of a Protease Turnover Assay for Clinical Discrimination of Mucinous Pancreatic Cysts
Suresh, V., Byers, K., Rajesh, U. C., Caiazza, F., Zhu, G., Craik, C. S., Kirkwood, K. S., Davisson, V. J., & Sheik, D. A. (2022) · Diagnostics · doi:10.3390/diagnostics12061343 · Cited by 6 · see citing works
Hong, S. B., Lee, N. K., Kim, S., Seo, H. I., Park, Y. M., Noh, B. G., Kim, D. U., Han, S. Y., & Kim, T. U. (2022) · Japanese Journal of Radiology · doi:10.1007/s11604-022-01312-y · Cited by 6 · see citing works
Abdelbaki, A., Li, Z., Pan, T.-Y., Lee, J., Chowdhury, A. R., Culp, S., Gnyawali, B., Maloof, T. G., Vishwanath, A. B., Reddy, S. N., et al. (2025) · Techniques and Innovations in Gastrointestinal Endoscopy · doi:10.1016/j.tige.2025.250924 · Cited by 5 · see citing works
Comandatore, A., Franco, G. D., Garajová, I., Panaitescu, A., Ausania, F., Giannessi, L., Furbetta, N., Guadagni, S., Milanetto, A. C., Pasquali, C., et al. (2025) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2025.06.001 · Cited by 4 · see citing works
Tashiro, Y., Kachi, M., Hashimoto, T., Takeyama, N., Ueda, Y., Munechika, J., & Ohgiya, Y. (2025) · Abdominal Radiology · doi:10.1007/s00261-025-04996-8 · Cited by 5 · see citing works
Terrin, M., Spadaccini, M., Poletti, V., Palma, C. D., Mercurio, M., minini, F., Spertino, M., Colombo, M., Andreozzi, M., Bonifacio, C., et al. (2025) · Digestive and Liver Disease · doi:10.1016/j.dld.2025.10.029 · Cited by 10 · see citing works
Hesse, F., Ritter, J., Hapfelmeier, A., Braren, R., & Phillip, V. (2023) · Pancreas · doi:10.1097/mpa.0000000000002264 · Cited by 4 · see citing works
Fukuda, K., Hozaka, Y., Oi, H., Tomita, M., Idichi, T., Yamasaki, Y., Kawasaki, Y., Hayashi, Y., Goto, Y., Sugiura, T., et al. (2025) · Pancreatology · doi:10.1016/j.pan.2025.08.001 · Cited by 4 · see citing works
Surveillance of Pancreatic Cystic Neoplasms
Chhoda, A., Schmidt, J., & Farrell, J. J. (2023) · Gastrointestinal Endoscopy Clinics of North America · doi:10.1016/j.giec.2023.03.010 · Cited by 4 · see citing works
Makino, Y., Oyama, K., Sagara, A., Thege, F. I., & Maitra, A. (2025) · Journal of Gastroenterology · doi:10.1007/s00535-025-02328-7 · Cited by 3 · see citing works
Tanaka, H., Matsusaki, S., Asakawa, H., Tsuruga, S., Nose, K., Kumazawa, H., Sakuno, T., Isono, Y., Sase, T., Okano, H., et al. (2022) · Internal Medicine · doi:10.2169/internalmedicine.9104-21 · Cited by 3 · see citing works
Farrell, J. J. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.11.014 · Cited by 3 · see citing works
Accurate Identification of Mucinous Pancreatic Cystic Lesions Using Small-Volume Analytes
Caiazza, F., Conroy, P. C., Ivry, S. L., York, T. J., Lin, J., Hernandez, S., Hoffmann, T. J., Francis, S. S., Park, W. G., Yip-Schneider, M., et al. (2022) · Journal of Surgical Research · doi:10.1016/j.jss.2022.08.014 · Cited by 2 · see citing works
Conditions at risk of pancreatic cancer: The radiology perspective
Cannella, R., Burgio, M. D., Maino, C., Matteini, F., Ippolito, D., Boraschi, P., Zamboni, G. A., & Vernuccio, F. (2025) · European Journal of Radiology · doi:10.1016/j.ejrad.2025.112119 · Cited by 2 · see citing works
Oppat, K. M., Bennett, F. J., & Maithel, S. K. (2024) · Surgical Clinics of North America · doi:10.1016/j.suc.2024.04.012 · Cited by 1 · see citing works
Pea, A., Dall’Olio, T., Solinas, D., Filippini, C., Venturini, E., Pastena, M. D., Luchini, C., Crinò, S. F., Zamboni, G. A., D’Onofrio, M., et al. (2026) · Annals of Surgical Oncology · doi:10.1245/s10434-026-19898-2 · Cited by 1 · see citing works
Kano, S., Gonoi, W., Nakaya, M., Inui, S., Nakai, Y., Masuoka, S., Masumoto, T., Minami, M., Gaballah, A. H., & Abe, O. (2026) · Radiographics · doi:10.1148/rg.250085 · Cited by 1 · see citing works
The Screening and Early Detection of Pancreatic Cancer: Who, When, and How?
Chang, J. H. (2020) · The Korean Journal of Pancreas and Biliary Tract · doi:10.15279/kpba.2020.25.2.65 · Cited by 1 · see citing works
Pancreatic Intraductal Papillary Mucinous Neoplasms: A Narrative Review
Paramythiotis, D., Karlafti, E., Fotiadou, G., Charalampidou, M., Karakatsanis, A., Ioannidis, A., & Michalopoulos, A. (2023) · Acta medica Lituanica · doi:10.15388/amed.2023.30.1.6 · Cited by 1 · see citing works
Long‐term Outcome after Observation and Surgical Treatment of Cystic Neoplasms
Salvia, R., Marchegiani, G., Perri, G., & Bassi, C. (2023) · doi:10.1002/9781119876007.ch97 · Cited by 1 · see citing works
Screening of Pancreatic Cancer for Early Diagnosis
Chang, J. H. (2021) · Korean Journal of Medicine · doi:10.3904/kjm.2021.96.2.110
Chalhoub, J. M., & Andrawes, S. (2021) · Clinical gastroenterology · doi:10.1007/978-3-030-69940-6_8
Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN with Associated Invasive Component
Wartenberg, M., & Karamitopoulou, E. (2021) · Encyclopedia of pathology · doi:10.1007/978-3-319-28845-1_5539-1
Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN with Associated Invasive Component
Wartenberg, M., & Karamitopoulou, E. (2022) · Encyclopedia of pathology · doi:10.1007/978-3-030-62416-3_5539
Marbles and Bubbles of the Pancreas: Imaging and Management of Pancreatic Solid and Cystic Lesions
Naamo, S., Chung, K., Rawal, S., Mpoy, M., & Ros, P. R. (2023) · Contemporary Diagnostic Radiology · doi:10.1097/01.cdr.0000990064.84915.68
Risk factors to to monitor to facilitate early diagnosis of pancreatic cancer
Kanno, A., Tanaka, A., Sakurai, Y., Ikeda, E., Ando, K., Yokoyama, K., & Yamamoto, H. (2024) · Suizo · doi:10.2958/suizo.39.205
Multianalyte blood-based risk stratification of incidental pancreas lesionsPreprint
Marcinak, C. T., Stephens, M. D., McDonald, B. R., Merali, N., Dietmann, E. C., McGregor, S. M., Ronnekleiv‐Kelly, S. M., Weber, S. M., Nkadori, E. N., Stadmeyer, P. G., et al. (2024) · medRxiv · doi:10.1101/2024.12.13.24318579
Current Considerations in Nonoperative Surveillance of Intraductal Papillary Mucinous Neoplasms
Mayhew, M. M., Buerlein, R. C. D., & Zaydfudim, V. M. (2025) · Digestive Disease Interventions · doi:10.1055/s-0045-1802658
Pancreatic Ductal Adenocarcinoma
Bello, R. J., & Clarke, C. N. (2025) · Springer eBooks · doi:10.1007/978-3-031-78409-5_16
Bravo, A. C., Cruz, R., Fernandes, A., Bispo, M., Boas, F. V., Gonçalves, T. C., Rodrigues‐Pinto, E., & Fidalgo, C. A. (2025) · GE Portuguese Journal of Gastroenterology · doi:10.1159/000549925
Mucinous vs. non-mucinous pancreatic cysts: diagnostic keys on CT and MRI
Burgio, M. D., Ronot, M., Chassaing, C., Copin, P., Dokmak, S., Cros, J. F., Rebours, V., de Mestier, L., Vilgrain, V., Sartoris, R., et al. (2026) · Abdominal Radiology · doi:10.1007/s00261-026-05509-x
Aleotti, F., Andreasi, V., Arru, G. G., Belfiori, G., Partelli, S., Pecorelli, N., Palumbo, D., Marmorale, C., COBELLI, F. D., Capurso, G., et al. (2026) · Updates in Surgery · doi:10.1007/s13304-026-02654-2
Rizzo, G. E. M., Infantino, G., Marchegiani, G., Machicado, J. D., Chiaro, M. D., Tarantino, I., Rossi, G., Arcidiacono, P. G., Vanella, G., Guilabert, L., et al. (2026) · World Journal of Clinical Oncology · doi:10.5306/wjco.v17.i5.120600
Toshima, F., Inoue, D., Kozaka, K., Yoneda, N., Komori, T., Takamatsu, A., 裕一, 中., & Kobayashi, S. (2026) · Japanese Journal of Radiology · doi:10.1007/s11604-026-02067-6
Indications for Non-operative Management for IPMN
Saeidishahri, S., Ebadinejad, A., & Serrano, O. K. (2026) · Springer eBooks · doi:10.1007/978-3-032-28601-7_21
- Authors
- Tanaka, M.
- Affiliations
- Shimonoseki City Hospital (JP)
- Corresponding author
- Tanaka, Masao
- ORCID
- Tanaka, Masao
- Venue
- Pancreas
- Published
- 2018-05
- Volume
- 47
- Issue
- 5
- Pages
- 544-550
- ISSN
- 0885-3177 (ISSN-L)
- 1536-4828
- OpenAlex
- W2801701284
- Cited by
- 76
- References
- 67
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 9 · 2023: 12 · 2022: 10 · 2021: 11 · 2020: 5 · 2019: 8 · 2018: 3
- FWCI
- 0.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pancreas (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Medicine › Epidemiology › Neuroendocrine Tumor Research Advances
- Keywords
- intraductal papillary mucinous neoplasm, pancreatic ductal adenocarcinoma, early detection, pancreatic cancer screening, branch duct IPMN, main duct IPMN, metachronous carcinoma, synchronous multiple primary cancers, invasive carcinoma, surveillance (medicine), precursor lesions
- MeSH terms
- Adenocarcinoma, Adenocarcinoma, Mucinous, Carcinoma, Papillary, Humans, Pancreas, Pancreatic Neoplasms, Disease Progression, Carcinoma, Pancreatic Ductal, Early Detection of Cancer
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
