The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Asymptomatic Colonization by Clostridium difficile in Infants: Implications for Disease in Later Life
Abstract
Approximately 60% to 70% of healthy newborns and infants are colonized by the enteric pathogen Clostridium difficile. For reasons that remain obscure, these colonized infants show no ill effects from the potent exotoxins released by this anaerobe, in contrast to older children and adults who are susceptible to severe diarrhea and colitis. The organism is acquired in infancy, as in adults, from environmental contamination in the nursery or home environment. Between 12 and 24 months C difficile is evicted as a commensal, presumably by the gradual development of the adult colonic microflora. The carrier state is well tolerated by infants, and the immunoglobulin G antitoxin response that develops during the carrier state appears to provide durable protection against subsequent C difficile disease.
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Penders, J., Thijs, C., van den Brandt, P. A., Kummeling, I., Snijders, B., Stelma, F., Adams, H., van Ree, R., & Stobberingh, E. E. (2007) · Gut · doi:10.1136/gut.2006.100164 · Cited by 844
Stark, P. L., & Lee, A. (1982) · Journal of Medical Microbiology · doi:10.1099/00222615-15-2-189 · Cited by 616
Colonization of the large bowel by Clostridium difficile in healthy infants: quantitative study
Stark, P. L., Lee, A., & Parsonage, B. D. (1982) · Infection and Immunity · doi:10.1128/iai.35.3.895-899.1982 · Cited by 104
Clostridia isolated from the feces of infants during the first year of life
Stark, P. L., & Lee, A. (1982) · The Journal of Pediatrics · doi:10.1016/s0022-3476(82)80430-7 · Cited by 80
Cited by
McDonald, L. C., Gerding, D. N., Johnson, S., Bakken, J. S., Carroll, K. C., Coffin, S. E., Dubberke, E. R., Garey, K. W., Gould, C. V., Kelly, C., et al. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/cix1085 · Cited by 2,690
Intestinal colonization resistance
Lawley, T. D., & Walker, A. W. (2013) · Immunology · doi:10.1111/j.1365-2567.2012.03616.x · Cited by 610
Understanding the mechanisms of faecal microbiota transplantation
Khoruts, A., & Sadowsky, M. J. (2016) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2016.98 · Cited by 561
Buss, S. N., Leber, A., Chapin, K., Fey, P. D., Bankowski, M. J., Jones, M. K., Rogatcheva, M., Kanack, K. J., & Bourzac, K. M. (2015) · Journal of Clinical Microbiology · doi:10.1128/jcm.02674-14 · Cited by 554
Clostridium difficile Infection in Infants and Children
COMMITTEE ON INFECTIOUS DISEASES, Schutze, G. E., Willoughby, R. E., Brady, M. T., Byington, C. L., Davies, H. D., Edwards, K. M., Glode, M. P., Jackson, M. A., Keyserling, H. L., et al. (2013) · PEDIATRICS · doi:10.1542/peds.2012-2992 · Cited by 256
Metadata
- Authors
- Jangi, S., & Lamont, J. T.
- Venue
- Journal of Pediatric Gastroenterology and Nutrition
- Publisher
- Wiley
- Published
- 2010-07
- Volume
- 51
- Issue
- 1
- Pages
- 2-7
- ISSN
- 0277-2116 (ISSN-L)
- 1536-4801
- OpenAlex
- W2034676061
- Cited by
- 305
- References
- 4
- FWCI
- 6.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jangi, S., & Lamont, J. T. (2010). Asymptomatic Colonization by Clostridium difficile in Infants: Implications for Disease in Later Life. Journal of Pediatric Gastroenterology and Nutrition. https://doi.org/10.1097/mpg.0b013e3181d29767
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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