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Cited by 187Nutritional Studies and DietFatty Acid Research and HealthDietary Effects on Health

Mediterranean Diet and Prevention of Chronic Diseases

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Romagnolo, Donato F., Selmin, Ornella I.·2017·Nutrition Today
DOI 10.1097/nt.0000000000000228PMC PMC5625964
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Abstract

A large body of research data suggests that traditional dietary habits and lifestyle unique to the Mediterranean region (Mediterranean diet, MD) lower the incidence of chronic diseases and improve longevity. These data contrast with troubling statistics in the United States and other high income countries pointing to an increase in the incidence of chronic diseases and the projected explosion in cost of medical care associated with an aging population. In 2013, the MD was inscribed by UNESCO in the “Representative List of the Intangible Cultural Heritage of Humanity.” The 2015–2020 Dietary Guidelines for Americans included the MD as a healthy dietary pattern. Therefore, specific objectives of this article are to provide an overview of the nutritional basis of this healthful diet, its metabolic benefits, and its role in multiple aspects of disease prevention and healthy aging. Whereas recommendations about the MD often focus on specific foods or bioactive compounds, we suggest that the eating pattern as a whole likely contributes to the health promoting effects of the MD.

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  • Human intervention studies have shown that consumption of a Mediterranean diet can dramatically reduce the incidence of neurodegenerative disorders, psychiatric conditions, cancer, and cardiovascular disease.

    “Human intervention studies have shown that the consumption of a Mediterranean diet can dramatically reduce the incidence of neurodegenerative disorders (Karstens et al., 2019;Romagnolo and Selmin, 2017;Scarmeas et al., 2006), psychiatric conditions, cancer (Schwingshackl et al., 2017) and cardiovascular disease (CVD (Bonaccio et al., 2013;Tsivgoulis et al., 2015;Wu and Sun, 2017)).”

    From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Romagnolo and Selmin, 2017

    The Neurodegenerative Diseases section (page unavailable) reports an association between greater Mediterranean-diet adherence and reduced incidence of Alzheimer’s disease and cognitive decline. It describes observational and prospective evidence, not human intervention studies demonstrating a dramatic reduction in neurodegenerative disorders. The other conditions in the citing sentence have separate citations and are not assessed here. (LLM, conf=0.88)

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Cited by

Sorted by citations

Authors
Romagnolo, D. F., & Selmin, O. I.
Affiliations
University of Arizona (US)
Corresponding author
Romagnolo, Donato F.
ORCID
Selmin, Ornella I.
Venue
Nutrition Today
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2017-09
Volume
52
Issue
5
Pages
208-222
ISSN
  • 0029-666X (ISSN-L)
  • 1538-9839
DOI
10.1097/nt.0000000000000228
PMC
PMC5625964
OpenAlex
W2749187798
Cited by
187
References
7
Citations by year
2026: 13 · 2025: 21 · 2024: 20 · 2023: 18 · 2022: 24 · 2021: 39 · 2020: 21 · 2019: 18 · 2018: 11 · 2017: 2
FWCI
13.35
Type
journal article
Language
en
Open access
Licence
Locations
  • Nutrition Today (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
  • U.S. Department of Defense (W81XWH)
  • U.S. Department of Agriculture
  • University of Arizona Cancer Center (CA023074, P30CA023074)
  • University of Arizona (P30CA023074, CA023074)
  • National Institute of Food and Agriculture
  • National Cancer Institute (P30CA023074)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Health Sciences › Medicine › Physiology › Dietary Effects on Health
Keywords
Mediterranean diet, chronic disease prevention, healthy eating patterns, dietary guidelines, healthy aging, metabolic benefits, lifestyle, bioactive compounds, UNESCO Intangible Cultural Heritage, Dietary Guidelines for Americans

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