Evaluation of self-collected versus clinician-collected swabs for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae pharyngeal infection among men who have sex with men.
Abstract
In Brief We evaluated self-sampling to detect pharyngeal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among men who have sex with men attending a San Francisco STD clinic. The prevalence of pharyngeal NG and CT infection was 6.7% (32/480) and 1.3% (6/480), respectively. The percent agreement between self-collected and clinician-collected NG and CT specimens using nucleic acid amplification testing was 96.6% with a κ of 0.766 (95% confidence interval: 0.653–0.879) and 99.4% with a κ of 0.766 (95% confidence interval: 0.502–1.000), respectively. Acceptability was high among participants. Our study found excellent agreement between self-collected and clinician-collected specimens using nucleic acid amplification testing to detect pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae infection among men who have sex with men attending a San Francisco STD clinic.
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Self-collected swabs have been reported to be an acceptable means of collection for pharyngeal and rectal specimens, which can enhance patient comfort and reduce clinical workloads.
“Self-collected swabs have been reported to be an acceptable means of collection for pharyngeal and rectal specimens (217–219), which can enhance patient comfort and reduce clinical workloads.”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [219]
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- Authors
- Freeman, A. H., Bernstein, K. T., Kohn, R. P., Philip, S., Rauch, L. M., & Klausner, J. D.
- Affiliations
- George Washington University (US)
- San Francisco Department of Public Health (US)
- University of California, San Francisco (US)
- Corresponding author
- Freeman, Alexandra H.
- Bernstein, Kyle T.
- Kohn, Robert P.
- Philip, Susan
- Venue
- Sexually Transmitted Diseases
- Published
- 2011-11
- Volume
- 38
- Issue
- 11
- Pages
- 1036-1039
- ISSN
- 0148-5717 (ISSN-L)
- OpenAlex
- W2081461223
- Cited by
- 58
- References
- 26
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 8 · 2023: 4 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 5 · 2015: 6 · 2014: 4 · 2013: 4 · 2012: 2
- FWCI
- 3.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sexually Transmitted Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- Chlamydia trachomatis, Neisseria gonorrhoeae, pharyngeal infection, men who have sex with men, nucleic acid amplification tests, STD clinic attendees, acceptability
- MeSH terms
- Chlamydia Infections, Chlamydia trachomatis, Gonorrhea, Humans, Male, Neisseria gonorrhoeae, Patient Acceptance of Health Care, Pharyngeal Diseases, Pharynx, Physician's Role, San Francisco, Self Care, Specimen Handling, Prevalence, Homosexuality, Male, Nucleic Acid Amplification Techniques
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