The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Effectiveness of Cognitive Behavioral Therapy for Depression and Anxiety in Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis
Open accessAbstract
OBJECTIVE: Depression and anxiety are highly prevalent in patients with cardiovascular disease (CVD) and influence their mental well-being and CVD prognosis. The primary objective was to assess the effectiveness of cognitive behavioral therapy (CBT) for depression and anxiety in patients with CVD. Secondary objectives were to assess the impact of CBT on cardiovascular mortality, cardiovascular events, patient satisfaction, and quality of life. METHODS: MEDLINE, PsycINFO, CINAHL, CENTRAL, and alternative sources were searched for randomized controlled trials and observational studies with a control. Studies were required to assess CBT in coronary heart disease, acute coronary syndrome, atrial fibrillation, or postmyocardial infarction patients, with anxiety and/or depression. Studies were independently screened by two reviewers and critically appraised using the Cochrane Risk of Bias tool. The random-effects model was used to pool standardized mean differences (SMD). RESULTS: Twelve randomized controlled trials were included. At follow-up, depression (SMD = -0.35, 95% confidence interval [CI] = -0.52 to -0.17, p < .001, I = 59%) and anxiety (SMD = -0.34, 95% CI = -0.65 to -0.03, p = .03, I = 71%) scores were significantly lower in CBT patients compared with controls. Change in mental health quality of life (SF-12) was also significantly greater for CBT patients, compared with controls (mean difference = 3.62, 95% CI = 0.22 to 7.02, p = .04, I = 0%). No differences in patient satisfaction or cardiovascular events were evident between CBT and control groups. Among the study reports included in this meta-analysis, data specific to cardiovascular mortality were not reported. CONCLUSIONS: Cognitive behavioral therapy seems to be an effective treatment for reducing depression and anxiety in patients with CVD and should be considered in standard clinical care.
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“Psychological treatment of anxiety and depression has small to moderate efficacy in this group and is not commonly based on a model of causal mechanisms.”
From Metacognitive beliefs and their relationship with anxiety and depression in physical illnesses: A systematic review (2020) · cites this paper as [18]
In the citing paper
“Whilst CBT significantly decreased symptoms, the effect sizes were small for depression (Cohen’s d = 0.35) and anxiety (Cohen’s d = 0.34) [18].”
From Metacognitive beliefs and their relationship with anxiety and depression in physical illnesses: A systematic review (2020) · cites this paper as [18]
Citations
Cites
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Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
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Cited by
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Comorbid depression in medical diseases
Gold, S. M., Köhler‐Forsberg, O., Moss-Morris, R. E., Mehnert-Theuerkauf, A., Miranda, J. J., Bullinger, M., Steptoe, A., Whooley, M. A., & Otte, C. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0200-2 · Cited by 583
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Piepoli, M. F., Abreu, A., Albus, C., Ambrosetti, M., Brotons, C., Catapano, A. L., Corrà, U., Cosyns, B., Deaton, C., Graham, I. M., et al. (2019) · European Journal of Preventive Cardiology · doi:10.1177/2047487319893035 · Cited by 226
“Another meta-analysis showed the efficacy of cognitive psychotherapy for reducing psychological symptoms in patients with CVD and significant symptoms of depression and anxiety,(157) but there was no effect on cardiovascular events.(157) However, a recent trial has shown for the first time a favourable effect of antid…”
BackgroundDepression and cardiovascular disease: The deep blue sea of women's heart
Bucciarelli, V., Caterino, A. L., Bianco, F., Caputi, C. G., Salerni, S., Sciomer, S., Maffei, S., & Gallina, S. (2019) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.05.001 · Cited by 209
Kovacs, A. H., Brouillette, J., Ibeziako, P. I., Jackson, J. L., Kasparian, N. A., Kim, Y. Y., Livecchi, T., Sillman, C., & Kochilas, L. K. (2022) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/hcq.0000000000000110 · Cited by 199
Metadata
- Authors
- Reavell, J., Hopkinson, M., Clarkesmith, D., & Lane, D. A.
- Affiliations
- Sandwell & West Birmingham Hospitals NHS Trust (GB)
- Corresponding author
- Lane, Deirdre A.
- Venue
- Psychosomatic Medicine
- Published
- 2018-10
- Volume
- 80
- Issue
- 8
- Pages
- 742-753
- ISSN
- 0033-3174 (ISSN-L)
- 1534-7796
- OpenAlex
- W2883745162
- Cited by
- 189
- References
- 34
- Citations by year
- 2026: 14 · 2025: 17 · 2024: 28 · 2023: 24 · 2022: 36 · 2021: 34 · 2020: 23 · 2019: 12
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- green
- vbn.aau.dk
- Licence
- other-oa
- Locations
- Psychosomatic Medicine (publishedVersion)
- PubMed (publishedVersion)
- VBN Forskningsportal (Aalborg Universitet) (submittedVersion, other-oa)
- Funders
- Bristol-Myers Squibb
- Pfizer
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive behavioral therapy, depression, anxiety, cardiovascular disease, coronary artery disease, acute coronary syndrome, atrial fibrillation, post-myocardial infarction, quality of life, cardiovascular mortality, cardiovascular events, patient satisfaction
- MeSH terms
- Anxiety Disorders, Cardiovascular Diseases, Depressive Disorder, Humans, Comorbidity, Cognitive Behavioral Therapy, Outcome Assessment, Health Care
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