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Mindfulness Training and Physical Health: Mechanisms and Outcomes
Open accessAbstract
Objective: There has been substantial research and public interest in mindfulness interventions, biological pathways, and health for the past two decades. This article reviews recent developments in understanding relationships between mindfulness interventions and physical health. Methods: A selective review was conducted with the goal of synthesizing conceptual and empirical relationships between mindfulness interventions and physical health outcomes. Results: Initial randomized controlled trials in this area suggest that mindfulness interventions can improve pain management outcomes among chronic pain populations, and there is preliminary evidence for mindfulness interventions improving specific stress-related disease outcomes in some patient populations (i.e., clinical colds, psoriasis, irritable bowel syndrome, posttraumatic stress disorder, diabetes, HIV). We offer a stress-buffering framework for the observed beneficial effects of mindfulness interventions and summarize supporting biobehavioral and neuroimaging studies that provide plausible mechanistic pathways linking mindfulness interventions with positive physical health outcomes. Conclusions: We conclude with new opportunities for research and clinical implementations to consider in the next two decades.
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“MBIs have been shown to decrease inflammation42,43”
From Feasibility, Acceptability, and Efficacy of Mindfulness Training in People With Upper Motor Neuron Disorders: A Systematic Review (2022) · cites this paper as [43]
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“decrease cortisol levels by altering hypothalamic-pituitary-adrenal axis function,42–45”
From Feasibility, Acceptability, and Efficacy of Mindfulness Training in People With Upper Motor Neuron Disorders: A Systematic Review (2022) · cites this paper as [43]
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“Creswell et al 32,33 suggest that mindfulness interventions foster resilience to stress in the brain by enhancing connectivity within stress regulatory regions of the prefrontal cortex and decreasing connectivity in regions of the brain controlling the fight-or-flight stress response.”
From Nursing Implications of Mindfulness-Informed Interventions for Stroke Survivors and Their Families. (2022) · cites this paper as [33]
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“Furthermore, their work suggests that mindfulness training can buffer the sympathetic nervous system and hypothalamicpituitary-adrenal response to acute stress.”
From Nursing Implications of Mindfulness-Informed Interventions for Stroke Survivors and Their Families. (2022) · cites this paper as [33]
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“Intervention studies have shown promising results for mindfulness interventions in patients living with long term health conditions and chronic pain (31, 32).”
From Mindfulness as Predictor of Itch Catastrophizing in Patients With Atopic Dermatitis: Results of a Cross-Sectional Questionnaire Study (2021) · cites this paper as [32]
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“the burgeoning literature on mindfulness for various medical conditions and for promoting behavior change has been promising. 77”
From Randomized Controlled Trials of Mindfulness and Acceptance-Based Interventions Over the Past Two Decades: A Bibliometric Analysis. (2021) · cites this paper as [77]
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“Mindfulness practices help reduce stress by altering brain structures and activity in regions associated with attention and emotional regulation [36,37].”
From The Impact of an Online Mindfulness-Based Practice Program on the Mental Health of Brazilian Nurses during the COVID-19 Pandemic (2023) · cites this paper as [37]
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Cites
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“The central nucleus of the amygdala has long been considered an important node for gating the central stress response (50,51), and recent studies suggest that mindful awareness and mindfulness interventions are associated withmodulations in amygdala structure and function (52–55).”
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“Indeed, the extant mindfulness intervention RCT outcomes described previously are consistent with this framework, because stress is known to trigger the onset or exacerbation of symptoms in chronic pain, psoriasis, IBS, PTSD, and diabetes (46).”
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Alterations in brain and immune function produced by mindfulness meditation
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Cited by
Sorted by citations
Items 101–200 of 252
Naude, C., Skvarc, D., Biurra, Y. C., Blake, L., Evans, S., Knowles, S. R., Eric, O., Prasertsung, C., Russell, L., Bassili, A., et al. (2024) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2024.111984 · Cited by 9
Linz, R., Puhlmann, L. M. C., Engert, V., & Singer, T. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105800 · Cited by 8
EFFECT OF EXERCISE INTERVENTION AND REHABILITATION ON PATIENTS WITH DEPRESSION
Shen, Y. (2022) · Revista Brasileira de Medicina do Esporte · doi:10.1590/1517-8692202329012022_0157 · Cited by 8
Ong, A. D., Moskowitz, J. T., Wethington, E., Addington, E. L., Sanni, M. O., Goktas, S., Sluys, E., Swong, S., Kim, P., & Reid, M. C. (2022) · PsyArXiv (OSF Preprints) · doi:10.1016/j.cct.2022.106880 · Cited by 8
“Mindfulness, defined as the process of openly attending to the present moment [71], is a widely used and empirically supported psychosocial treatment for chronic pain [72].”
BackgroundMeasuring mindfulness: A systematic review and evaluation of self-report mindfulness scales
Chems-Maarif, R., Cavanagh, K., Baer, R., Gu, J., & Strauss, C. (2026) · Clinical Psychology Review · doi:10.1016/j.cpr.2026.102719 · Cited by 7
Huang, S., Riccardi, D., Pflanzer, S., Redwine, L. S., Gray, H. L., Carson, T. L., McDowell, M., Thompson, Z., Hubbard, J. J., & Pabbathi, S. R. (2023) · Nutrients · doi:10.3390/nu15194205 · Cited by 7
Kwon, C. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20053807 · Cited by 7
“Mindfulness training has also been reported to benefit individuals with physical illnesses such as chronic pain, common cold, psoriasis, irritable bowel syndrome, and diabetes [3].”
BackgroundENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices
Ganesan, S., Barrios, F. A., Batta, I., Bauer, C. C. C., Braver, T. S., Brewer, J. A., Brown, K. W., Cahn, B. R., Cain, J. A., Calhoun, V. D., et al. (2024) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2024.10.015 · Cited by 7
Self-citationMüller, L., Rapoport, O., & Rahe, M. (2024) · Mindfulness · doi:10.1007/s12671-024-02467-7 · Cited by 9
“Furthermore, Creswell et al. (2019) suggested that mindfulness interventions train central stress resilience pathways in the brain, which may buffer stress and boost positive emotions.”
Mindfulness, self-reported health, and cortisol: A latent profile analysis
Leach, S. M., Mitchell, A. M., Salmon, P. M., & Sephton, S. E. (2020) · Journal of Health Psychology · doi:10.1177/1359105320931184 · Cited by 7
Clark, E., Gulley, L. D., Prince, M. A., Casamassima, M., Sánchez, N., Jimenez, V., Johnson, S. A., Miller, R. L., Conte, I., Kaar, J. L., et al. (2021) · Journal of Behavioral Medicine · doi:10.1007/s10865-021-00225-x · Cited by 7
Miniati, M., Orrù, G., Paroli, M., Cinque, M., Paolicchi, A., Gemignani, A., Perugi, G., Ciacchini, R., Marazziti, D., Palagini, L., et al. (2023) · PubMed Central · doi:10.36131/cnfioritieditore20230505 · Cited by 7
Roychowdhury, D. (2021) · Asian Journal of Sport and Exercise Psychology · doi:10.1016/j.ajsep.2021.09.004 · Cited by 8
Komariah, M., Maulana, S., Amirah, S., Platini, H., Rahayuwati, L., Yusuf, A., & Firdaus, M. K. Z. H. (2025) · JMIR Cancer · doi:10.2196/54154 · Cited by 11
“…(the regulatory and reactivity pathways) and may enhance the regulation of the stress reactivity of the hypothalamic-pituitary-adrenal and sympathetic-adrenal-medullary axes, thereby elucidating the effects of mindfulness interventions on stress-related health and disease outcomes over time [51].”
Assessing a Structured Mental Fitness Program for Academic Acute Care Surgeons: A Pilot Study
Bhat, S. G., Nagaraj, M. B., Balentine, C. J., Hogan, T. P., Meier, J., Prince, H. B., AbdelFattah, K. R., Zeh, H. J., & Lévi, B. (2023) · Journal of Surgical Research · doi:10.1016/j.jss.2023.09.052 · Cited by 6
Puhlmann, L. M. C., Vrtička, P., Linz, R., Valk, S. L., Papassotiriou, I., Chrousos, G. P., Engert, V., & Singer, T. (2024) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2024.100414 · Cited by 7
“Thus, overall, our fi ndings add to the growing literature on positive neurobiological changes following contemplative training (30,37,44,108), including enhanced neuroplasticity (58,104,109), and support the hypothesis that neurotrophins such as BDNF mediate these changes, potentially in…”
Valencia, L. P., Arampatzis, D., Beck, H., Dreinhöfer, K., Drießlein, D., Mau, W., Zimmer, J., Schäfer, M., Steinfeldt, F., & Wippert, P. (2021) · Trials · doi:10.1186/s13063-021-05823-3 · Cited by 6
Mindfulness stress-buffering model of health: implications for successful aging
MacAulay, R. K., Brown, L. F., & Moore, L. (2022) · Aging & Mental Health · doi:10.1080/13607863.2022.2107175 · Cited by 9
“Trait mindfulness is reliably associated with reduced stress and NA, which theoretically could have distal effects on health outcomes (Creswell et al., 2019).”
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“12,13 The longer the patient uses this tool, the greater the effect on LC-associated autonomic dysfunction, which is hypothesized to decrease symptom burden.”
Xu, L., Guan, A., & Huang, Y. (2025) · Medicine · doi:10.1097/md.0000000000041870 · Cited by 5
“[6,16,17] Because of the rapid advancement of information technology, a number of online platforms, including online MBIs, have been used to deliver mental health interventions.”
Chua, J. Y., Long, V. S., Yeo, P. M., Ding, J., Dua, J. P. L., Chandran, N. S., Lim, Q., Tow, H. X. S., Sim, W., Ing, C. W., et al. (2025) · JAAD International · doi:10.1016/j.jdin.2025.09.017 · Cited by 5
Dinesh, T. K., Shetty, A., Gil, M. T., & Dsouza, K. J. (2022) · Economic Research-Ekonomska Istraživanja · doi:10.1080/1331677x.2022.2154237 · Cited by 5
“Creswell et al. (2019) posits that stressful workplace scenarios have highlighted the significance of mindfulness where emerging contributions have been seen in clinical trials presently visualized at its infancy in different organizational settings (Aikens et al., 2014) though not reflected in the…”
BackgroundHeredia, L., Ventura, D., Torrente, M., & Vicens, P. (2024) · Mind Brain and Education · doi:10.1111/mbe.12419 · Cited by 7
Zen Meditation and the Neuro-Immuno-Endocrine Axis
Ring, H. Z., & Kern, R. (2024) · Health · doi:10.4236/health.2024.1612086 · Cited by 5
Banariu, G. M. (2021) · Acta Endocrinologica (Bucharest) · doi:10.4183/aeb.2021.486 · Cited by 6
Onofrei, L. M., Puiu, M., Chiriță-Emandi, A., & Șerban, C. L. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1368069 · Cited by 5
Serpa, J. G., Atwood, K., Shamblen, S. R., Sangpukdee, A., Jents, M. A., & Wolf, C. (2022) · Mindfulness · doi:10.1007/s12671-022-01905-8 · Cited by 5
“Mindfulness-Based Interventions (MBIs) are a rapidly growing field described as an emerging trend (Baminiwatta & Solangaarachchi, 2021) in terms of the diversity of interventions, evidence-basis, and ubiquity (Creswell et al., 2019; Khoury et al., 2013).”
BackgroundGarfin, D. R., Cipres, A. L., & Reyes, R. M. (2021) · doi:10.15406/ijcam.2021.14.00534 · Cited by 6
Preventive Treatment of Migraine
Todd, C., Sandoe, C. H., & Lay, C. L. (2022) · Seminars in Neurology · doi:10.1055/a-1933-4366 · Cited by 5
Loucks, E. B., Rosenkranz, M. A., & Creswell, J. D. (2021) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000961 · Cited by 6
“stress burdens are the most likely to experience health benefits from mindfulness interventions (57,61) although more research is still needed.”
BackgroundSelf-citationColaianne, B. A. (2025) · Journal of Adolescence · doi:10.1002/jad.70020 · Cited by 5
Campo, C., Cellucci, F., Treggiari, G., Spedicato, G. A., Lasaponara, S., & Conversi, D. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1755043 · Cited by 5
“Thus, this improvement suggests that mindfulness-based training positively affects the athletes’ overall balance of the ANS, potentially contributing to improved stress adapt-ability, mental and physical health (Kemp and Quintana, 2013), and Plot (mean and 95% CI error bars) of variations from T0 to T1 in MAIA scores…”
InfluentialRosen, J., & Penque, S. (2022) · Journal of the American Psychiatric Nurses Association · doi:10.1177/10783903221108767 · Cited by 4
“The outcome of mindfulness may be a more effective response to the situation and may promote health (Bartlett et al., 2019; Creswell et al., 2019; Tang & Braver, 2020).”
BackgroundGvozden, M., Perunicic-Mladenovic, I., Purić, D., & Krstić, K. (2025) · Mindfulness · doi:10.1007/s12671-025-02580-1 · Cited by 6
“Mindfulness also targets physiological, neurological, and behavioral processes associated with psychological stress (Black & Slavich, 2016; Creswell et al., 2019; Paulus, 2016; Slagter et al., 2011; Tang et al., 2016).”
Puhlmann, L. M. C., & Engert, V. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1415081 · Cited by 5
Zhang, J., Zheng, Z., Wang, L., Luberto, C. M., Zhang, M., Wen, Y., Su, Q., & Jiao, C. (2022) · Behavior Therapy · doi:10.1016/j.beth.2022.04.004 · Cited by 4
Dispositional mindfulness: Is it related to knee osteoarthritis population’s common health problems?
Chu, S., Lin, L., Chiu, A., & Wang, H. (2024) · PLoS ONE · doi:10.1371/journal.pone.0299879 · Cited by 5
“…positive affect, improve social connectedness, and help individuals develop interpersonal relationships, as well as alter biological pathways that affect health (e.g., neuroendocrine function, the immune system, and the autonomic nervous system), ultimately improving physical health outcomes [12].”
BackgroundNyklíček, I., Boxtel, G. J. M. V., van der Donk, L. J., Kop, W. J., & Lodder, P. (2024) · Mindfulness · doi:10.1007/s12671-024-02358-x · Cited by 4
“The few studies performed have yielded inconsistent findings (Creswell et al., 2019; Morton et al., 2020).”
Asadollah, F., Nikfarid, L., Nourian, M., & Hashemi, F. (2024) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000657 · Cited by 4
“43 They also improve adjustment and emotion by adjusting attention.”
Bermudo-Gallaguet, A., Ariza, M., Agudelo, D., Camins-Vila, N., Boldo, M., Peters, S., Sawicka, A. K., Dacosta‐Aguayo, R., Soriano-Raya, J. J., Vía, M., et al. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14082580 · Cited by 4
“MBIs are thought to promote psychological and physical health by modulating the body’s stress-response systems, including reducing the reactivity of the sympathetic nervous system (e.g., lowering catecholamines and blood pressure) and the hypothalamic– pituitary–adrenal (HPA) axis [39].”
Mindfulness: Why it may work and why it is sure to succeed
Errasti, J. M., Al‐Halabí, S., López-Navarro, E., & Álvarez, M. P. (2022) · Behavioral Psychology/Psicología Conductual · doi:10.51668/bp.8322112n · Cited by 4
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Assisting Focused Attention Meditation Through EEG-Based Alpha-Theta Cross-Frequency Neurofeedback
Vuyst, H.-J. D., Karaiskou, A.-Ι., Soriano, J. R., Pergens, J., de Beeck, R. O., der Gucht, K. V., Raes, F., Vos, M. D., Varon, C., & Alaerts, K. (2025) · Mindfulness · doi:10.1007/s12671-025-02603-x · Cited by 3
“While these practices vary in form, they are fundamentally rooted in the act of using one’s attention to observe the present moment with an attitude of non-judgmental acceptance and equanimity (Creswell et al., 2019; Kabat-Zinn, 2018).”
BackgroundGalluzzi, S., Solorzano, C. S., Marizzoni, M., Gatti, E., Gualco, C., Lanfredi, M., Rossi, R., Cattaneo, A., Frisoni, G. B., Crescentini, C., et al. (2025) · Mindfulness · doi:10.1007/s12671-025-02718-1 · Cited by 3
“However, modulation of the function of the stress system may be involved (Creswell et al., 2019; Taylor et al., 2010).”
Lamont, J. M. (2024) · Journal of Prevention and Health Promotion · doi:10.1177/26320770241238354 · Cited by 3
“Moreover, such interventions have also been shown to be effective at preventing poor health behaviors (Roche et al., 2019) and promoting positive health outcomes (Creswell et al., 2019).”
BackgroundPérez-Marqués, M. (2024) · Romanian Journal of Applied Psychology · doi:10.2478/rjap-2024-0005 · Cited by 5
Childbirth-related fear, tokophobia, and cognitive behavioral therapy
Martin, C. R., Jones, C., Marshall, C. A., & Jomeen, J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85757-4.00043-2 · Cited by 3
Addressing Stress Among Healthcare Workers Using Mindfulness-Based Interventions
Dave, P. (2024) · Asian Journal of Dental and Health Sciences · doi:10.22270/ajdhs.v4i2.89 · Cited by 3
Reply: The PHIOMM Framework for Implementing Mindfulness in Public Health, With Groundwork
Oman, D. (2025) · Mindfulness · doi:10.1007/s12671-025-02553-4 · Cited by 4
“…little systematic evidence that MBPs can support establishing novel proactive salutary behavioral routines, such as physical exercise routines (Creswell et al., 2019; for physical activity, Schneider et al., 2019 reported four null, two favorable, and one unfavorable randomized comparisons…”
Unveiling the mirage of mindfulness profiles through mindfulness-based stress reduction
Lecuona, O. Z., García‐Rubio, C., de Rivas, S., Vidal, J., Moreno‐Jiménez, J. E., & Rodríguez‐Carvajal, R. (2024) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2024.100775 · Cited by 2
Alhawatmeh, H. N., Najadat, I. A., & Hweidi, I. M. (2024) · International Journal of Nursing Practice · doi:10.1111/ijn.13282 · Cited by 2
Nunes, G. M., Paiva, S. D. P. C., Geber, S., Serra, A. S. V. D. A., Sampaio, M. A. C., & Tavares, R. L. C. (2024) · EXPLORE · doi:10.1016/j.explore.2024.103067 · Cited by 2
How Does Mindfulness Build Resilience? The Mediating Role of Hope
Dorais, S., Gutiérrez, D., Dukes, A. T., Niles, J. K., & Colon, M. L. (2025) · Counseling and Values · doi:10.1163/2161007x-bja10024 · Cited by 2
Chiu, D. T., Fein, F., Thompson‐Lastad, A., Hartogensis, W., Christian, S. N., Ekman, E., & Chao, M. T. (2025) · Global Advances in Integrative Medicine and Health · doi:10.1177/27536130251347913 · Cited by 2
“37,39 Low-income and racially and ethnically minoritized populations are less likely than their higher-income and White counterparts to participate in mindfulness-based interventions.”
Trait mindfulness: a potential health asset?
Bartlett, L., Roche, M., Bindoff, A. D., Roccati, E., Sinclair, D., & Vickers, J. C. (2025) · Journal of Public Health · doi:10.1007/s10389-025-02584-0 · Cited by 2
Habits of Mind: Mindful Awareness from a Habits Framework
Lipsett, M., Berkman, E. T., & Creswell, J. D. (2025) · Springer eBooks · doi:10.1007/978-3-031-91451-5_5 · Cited by 2
Self-citationMulhem, E., Zeman, L. L., Childers, K. L., Roy, S., & Homayouni, R. (2025) · PLoS ONE · doi:10.1371/journal.pone.0334752 · Cited by 2
Mindfulness Training for New Nursing Students Improves Stress Resilience and Well-Being
Schwartz‐Mette, R. A., Strout, K. A., Sapp, M., Carmone, S.-M., & Weirich, M. (2026) · Journal of Nursing Education · doi:10.3928/01484834-20250827-01 · Cited by 3
Associations between mindfulness and non-restorative sleep: the roles of resilience and handgrip
Li, S.-H., Jiang, Y., Shen, Z., Liao, Y., Zeng, Y.-H., & Ye, Z.-J. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1476197 · Cited by 2
Hebert, K., & Best, L. A. (2021) · Psychological applications and trends · doi:10.36315/2021inpact027 · Cited by 3
Mindfulness and Health: The Nursing Science Bridge
Saban, K. L., & Janusek, L. W. (2020) · Western Journal of Nursing Research · doi:10.1177/0193945920973748 · Cited by 2
“Yet, the investigation of the neuro-biologic mechanisms of mindfulness and how mindfulness promotes health is still in its infancy (Creswell et al., 2019; Greeson & Chin, 2019).”
BackgroundRESEARCH ON THE RELATIONSHIP BETWEEN SPORTS SCIENTIFIC TRAINING AND ATHLETES’ MENTAL HEALTH
Han, F. (2021) · Revista Brasileira de Medicina do Esporte · doi:10.1590/1517-8692202127042021_0096 · Cited by 2
“1 0 0 [ ] 0 cos sin 0 sin cos α α α α α = − The inverse matrix of equation (1) is:”
BackgroundA comparative analysis of body awareness in women practising yoga and volleyball players
Muda, A., & Długołęcka, A. (2021) · Physiotherapy Review · doi:10.5114/phr.2021.111809 · Cited by 2
Bases biológicas del mindfulness y su aplicación en la práctica clínica
Gómez, S. M., Peñaloza, M., Rodríguez, N. B., & Alba, L. H. (2022) · Universitas Médica · doi:10.11144/javeriana.umed63-2.mind · Cited by 4
“Existe evidencia de que las terapias basadas en mindfulness inducen cambios biológicos positivos en los sistemas nervioso, cardiovascular, inmunológico y hormonal, lo cual explica el auge de este tipo de aproximaciones como terapias complementarias en el manejo de patologías relacionadas con los sistemas mencionados (…”
BackgroundHashemzadeh, A., Hatami, H., Banijamali, S.-A., & Asadzade, H. (2022) · The Journal Of Psychological Science · doi:10.52547/jps.21.112.763 · Cited by 2
Managing Differences in the Workplace: Mindfulness-based Interventions
Yavuz, M. (2023) · Emerald Group Publishing Limited eBooks · doi:10.1108/s2051-233320230000009004 · Cited by 2
Mindfulness for Midwives: Supporting Health and Well‐Being for Our Clients and Ourselves
Kantrowitz‐Gordon, I., & Avery, M. D. (2023) · Journal of Midwifery & Women s Health · doi:10.1111/jmwh.13572 · Cited by 2
Reynolds, R. B. (2022) · Cross-cultural advancements in positive psychology · doi:10.1007/978-3-031-22288-7_18 · Cited by 1
Gobbo, M. E., Medrano, L. A., Parada, M. D. L. P. S., & Palau, F. G. (2024) · Neurología Argentina · doi:10.1016/j.neuarg.2024.02.002 · Cited by 5
Oliveira, M. L., Lima, N. S., Renaud, G. K., Estrada, A., Buitrago, D., Hamm, A., Nadeem, S., Naylor, K. B., Chen, Z., Yanez, B. R., et al. (2024) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00608.2024 · Cited by 1
Mindfulness and physical health among college students: A latent profile analysis
Jaurequi, M. E., Love, H., Taylor, S., & Barnes, A. (2025) · Journal of American College Health · doi:10.1080/07448481.2025.2459749 · Cited by 2
“15,17 Furthermore, mindfulness has been argued to counter stress and illness by enhancing the ability to accept discomfort and redirect attention from an unpleasant experience to more benign sensations, such as the breath or sense of ease elsewhere within the body.”
Joss, D., Sevinc, G., Denninger, J. W., Khalsa, S. B. S., Hoge, E. A., Bhasin, M., Dusek, J. A., Macklin, E. A., Libermann, T. A., Fricchione, G. L., et al. (2025) · Neuroscience Letters · doi:10.1016/j.neulet.2025.138272 · Cited by 1
Mind Power: A Holistic Mindful-Based Health Promotion Course for University Students
Ray, H. A., & Flessati, S. (2025) · Mindfulness · doi:10.1007/s12671-025-02648-y · Cited by 1
“Evidence also supports the positive neural, physiological, behavioral, and psychological mechanisms linking mindfulness with improved physical health (Creswell, et al., 2019).”
Non-pharmacological sedation techniques: The role of hypnosis, virtual reality, and other strategies
Nijs, K., Jorissen, C., Teunkens, A., de Velde, M. V., & Stessel, B. (2025) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2025.09.004 · Cited by 2
Cheng, S., Li, J., & Deng, L. (2025) · International Journal of Inclusive Education · doi:10.1080/13603116.2025.2560004 · Cited by 1
“While numerous scholars have confirmed the influence of mindfulness on physical health (Creswell et al. 2019; Murphy et al. 2012), for instance, Bazzano et al.’s (2018) randomised controlled trial involving elementary teachers demonstrated significant improvement in emotional and psychosocial…”
Mindfulness, Emotion Regulation, and Links to Behavioral Health
Heppner, W. L., & Spears, C. A. (2025) · Springer eBooks · doi:10.1007/978-3-031-91451-5_11 · Cited by 1
Alnabilsy, R., Israel, S., Soroker, I., & Levit‐Binnun, N. (2025) · Mindfulness · doi:10.1007/s12671-025-02687-5 · Cited by 1
“The quantitative findings confirmed well-established relationships between mindfulness, self-compassion, and mental well-being (Creswell et al., 2019; Gu et al., 2015; Querstret et al., 2020), consistent with cross-sectional evidence from other marginalized populations, including Orthodox Jews (Paz…”
Lindsay, E. K., Damon, S., Low, C. A., & Marsland, A. L. (2025) · Behavior Therapy · doi:10.1016/j.beth.2025.08.004 · Cited by 1
“MBIs show promise for targeting stress pathways, inflammatory mechanisms, and stress-related disease outcomes (Creswell et al., 2019), especially among people at heightened risk (Sanada et al., 2020).”
Self-citationVelázquez-Paniagua, M., Gomez‐Virgilio, L., Gómez-Chavarı́n, M., Cárdenas‐Aguayo, M. D. C., & Sampieri-Cabrera, R. (2026) · Discover Mental Health · doi:10.1007/s44192-025-00364-6 · Cited by 1
“The explanation for the effect of mindfulness on reducing levels of biomarkers, such as cortisol, is that this type of activity promotes the regulation of the hypothalamic-pituitary-adrenal (HPA) axis [7].”
Jin, X., Chen, J., & Zhang, X. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1769779 · Cited by 1
“…as mindfulness meditation, suggest a role for the prefrontal cortex (e.g., in top-down regulation), limbic system (e.g., amygdala reactivity), and striatum in emotion regulation, as well as modulation of inflammatory and stress-related gene expression (Tang et al., 2015; Creswell et al., 2019).”
Zhang, X., Luo, J., Zhang, H., Jiao, J., Qu, Z., Yin, J., & Zhang, H. (2026) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2026.103356 · Cited by 1
Non-pharmacological mental health interventions for law enforcement officers: A systematic review
Delgado, H. N., & Wu, Y. (2026) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2026.152098 · Cited by 1
Mind–Body Therapies for Multimorbidity: A Bibliometric Analysis and Evidence Map
Li, X., Yin, H., Li, Z., Wang, Y., Yuan, Y., Chen, R., Fang, J., & Liu, J. (2026) · Healthcare · doi:10.3390/healthcare14182902 · Cited by 1
“Mindfulness and related interventions may influence responses to stress, pain, and negative emotions through attention regulation, decentring, emotion regulation, and body awareness [31–33].”
Shahbazi, K., Taghvaei, M. H., Solati, S. K., Khaledifar, A., & Shahnazari, M. (2021) · doi:10.32592/ajnpp.2021.8.4.104 · Cited by 1
“Third, this intervention affects the regulation of emotion, self-awareness, attention control, and concentration through psychological mechanisms [29].”
BackgroundPacini, A., Všetečková, J., & Haider, S. (2022) · Clinical Gerontologist · doi:10.1080/07317115.2022.2093687 · Cited by 1
“The role of mindfulness and social relationships in physical health has been modeled by Cresswell, Lindsay, Vallalba, and Chin (2019).”
BackgroundMethodSamadi, B., Mirzaian, B., & Ghanadzadegan, H. A. (2024) · doi:10.61838/kman.jayps.5.5.5 · Cited by 1
Lifestyle Interventions to Manage Insulin Resistance
Babalola, O. O., Ottu, P. O., Akinnusi, E., Aturamu, P. O., & Iwaloye, O. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1005259 · Cited by 1
Outcomes of Mindfulness Therapy for Adolescents with Mental Health Issues: A Scoping Review
Sapulette, B. J., Prabhasuari, I. A. M., Zakiyah, H., Fatmawati, K. A., Soselisa, A. H., & Warsini, S. (2025) · Journal of Indian Association for Child and Adolescent Mental Health · doi:10.1177/09731342251360104 · Cited by 1
“34 40 Mindfulness also helps individuals avoid overreacting to negative emotions, which can reduce somatization symptoms such as physical pain or discomfort, often arising due to psychological stress.”
Mindfulness, Health and Wellbeing
Rahman, S., Prastuti, E., & Machmudah, M. (2021) · KnE Social Sciences · doi:10.18502/kss.v4i15.8189
Wu, Y.-F., Chen, M., Ye, J., Hong, J., Ye, J.-N., & Wu, Y.-T. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.847602 · Cited by 1
“, 2017), reducing perceived pain (Creswell et al., 2019), improving concentration (Norris et al.”
BackgroundPsychological and Clinical Theories
Lo, H. H. M. (2022) · Springer eBooks · doi:10.1007/978-981-16-3059-0_2-1 · Cited by 1
Stop Running Away from Stress: Practice Mindfulness Instead
Zaidi, F. Z., Ming, L. M., & Jumaat, A. (2022) · Advances in economics, business and management research/Advances in Economics, Business and Management Research · doi:10.2991/978-94-6463-080-0_26 · Cited by 1
Psychological and Clinical Theories
Lo, H. H. M. (2023) · Social Work · doi:10.1007/978-981-19-1015-9_2 · Cited by 1
Mindfulness Training and Health-Related Quality of Life in Male NCAA Division I AthletesPreprint
Haraldsdóttir, K., Anderson, S. C., Sanfilippo, J. L., McGehee, C., & Watson, A. M. (2023) · medRxiv · doi:10.1101/2023.03.09.23287051 · Cited by 1
Znaczenie mindfulness w miejscu pracy – możliwości pobudzania uważności pracowników
Syper‐Jędrzejak, M., & Bednarska‐Wnuk, I. (2019) · e-mentor · doi:10.15219/em79.1413 · Cited by 1
López-Montoyo, A. (2020) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) · doi:10.6035/14109.2020.261277
Typy podejścia do uważności młodych dorosłych w świetle wyników badań własnych
Dębska, E. (2021) · Rocznik Andragogiczny · doi:10.12775/ra.2021.005
Entspannungstherapie – Definition und Wirkungsmechanismen
Burch, C. (2021) · Springer eBooks · doi:10.1007/978-3-662-63513-1_2
McKenzie, S. P. (2022) · Springer eBooks · doi:10.1007/978-3-030-97170-0_6
Living with a Chronic Disorder: The Benefits of Mindfulness and Psychological Flexibility
Pracana, C., & Wang, M. (2021) · doi:10.36315/2021padvii23
Metadata
- Authors
- Creswell, J. D., Lindsay, E. K., Villalba, D. K., & Chin, B.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- Creswell, J. David
- Venue
- Psychosomatic Medicine
- Published
- 2019-04
- Volume
- 81
- Issue
- 3
- Pages
- 224-232
- ISSN
- 0033-3174 (ISSN-L)
- 1534-7796
- PMC
- PMC6613793
- OpenAlex
- W2913434882
- Semantic Scholar
- 8867cd2d818afb74ba3a269c72fa0e0653a68d13
- Cited by
- 252
- References
- 89
- Citations by year
- 2026: 30 · 2025: 49 · 2024: 41 · 2023: 28 · 2022: 46 · 2021: 36 · 2020: 14 · 2019: 8
- FWCI
- 4.12
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychosomatic Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Center for Complementary and Integrative Health (F32AT009508, R21AT008493, R01AT008685)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Health Professions › General Health Professions › Health, psychology, and well-being
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- mindfulness training, mindfulness-based interventions, physical health, chronic pain, stress buffering, stress-related disorders, psoriasis, irritable bowel syndrome, post-traumatic stress disorder, diabetes mellitus, HIV, neuroimaging, biobehavioral mechanisms
- MeSH terms
- Health Status, Humans, Inflammation, Stress, Psychological, Health Behavior, Mindfulness
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