How Does Mindfulness Training Affect Health? A Mindfulness Stress Buffering Account
Abstract
Initial well-controlled studies have suggested that mindfulness training interventions can improve a broad range of mental and physical health outcomes (e.g., HIV pathogenesis, depression relapse, inflammation, drug abuse), yet the underlying pathways linking mindfulness and health are poorly understood. In this article, we offer a mindfulness stress buffering account to explain these health outcomes, which posits that mindfulness-based health effects are mostly likely to be observed in high-stress populations for which stress is known to affect the onset or exacerbation of disease pathogenic processes. We then offer an evidence-based biological model of mindfulness, stress buffering, and health.
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Mindfulness-based practices promote acceptance of ill-health through non-judgemental observation of thoughts and feelings.
“Mindfulness-based practices employ strategies that promote acceptance of (ill-)health through non-judgemental observation of thoughts and feelings [1].”
Mindfulness has demonstrated strong utility for enhancing self-management and health outcomes in chronic illness.
“Mindfulness has demonstrated strong utility for enhancing self-management and health outcomes in chronic illness.”
Mindfulness is widely employed as an adjunctive strategy for health self-management in people with chronic health conditions.
“Mindfulness is widely employed as an adjunctive strategy for health self-management in people with chronic health conditions [1].”
Mindfulness-based stress reduction programs have been shown to ameliorate symptoms of anxiety, depression, and emotional dysregulation during global crises.
“Mindfulness-based stress reduction programs have been shown to ameliorate symptoms of anxiety, depression, and emotional dysregulation during global crises [182].”
From Impact of Media-Induced Uncertainty on Mental Health: Narrative-Based Perspective. (2025) · cites this paper as [182]
In older populations, MBIs including mindfulness-based cognitive therapy and ACT have shown promise in helping individuals cope with stress and uncertainty.
“In these populations, MBIs, including mindfulness-based cognitive therapy and ACT, have shown promise in helping individuals cope with stress and uncertainty [182,194,195].”
From Impact of Media-Induced Uncertainty on Mental Health: Narrative-Based Perspective. (2025) · cites this paper as [182]
Mindfulness principles and practices can foster self-regulation that may protect against biological and behavioral contributors to stress-related illness.
“Taken together, the core principles and practices of mindfulness can promote self-regulation that may ultimately “buffer” against biological processes and behaviors that contribute to stress-related disease [10].”
From Mindfulness and physical disease: a concise review (2019) · cites this paper as [10]
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“Being mindful enables people to be more aware and accepting of their experiences of the present moment, leading to reductions in stress levels and other negative outcomes (Colgan et al., 2019; Creswell & Lindsay, 2014).”
BackgroundSpecific reduction in the cortisol awakening response after socio-affective mental training
Engert, V., Hoehne, K., & Singer, T. (2023) · Mindfulness · doi:10.1007/s12671-023-02074-y · Cited by 17 · see citing works
Mindfulness During Pregnancy and Parental Stress in Mothers Raising Toddlers
Boekhorst, M. G. B. M., Potharst, E. S., Beerthuizen, A., Hulsbosch, L. P., Bergink, V., Pop, V. J. M., & Nyklíček, I. (2020) · Mindfulness · doi:10.1007/s12671-020-01392-9 · Cited by 17 · see citing works
Hartley, M., Due, C., & Dorstyn, D. (2022) · Disability and Rehabilitation · doi:10.1080/09638288.2021.1921859 · Cited by 15 · see citing works
“Letting Go” (Implicitly): Priming Mindfulness Mitigates the Effects of a Moderate Social Stressor
Bergeron, C. M., Almgren-Doré, I., & Dandeneau, S. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00872 · Cited by 11 · see citing works
Prochilo, G. A., Costa, R. J. S., Hassed, C., Chambers, R., & Molenberghs, P. (2021) · Pilot and Feasibility Studies · doi:10.1186/s40814-020-00751-6 · Cited by 12 · see citing works
O’Connor, E. J., Crozier, A. J., Murphy, A., & Immink, M. A. (2022) · Perceptual and Motor Skills · doi:10.1177/00315125221087523 · Cited by 12 · see citing works
The psychometric properties of the Vietnamese Version of the Five Facet Mindfulness Questionnaire
Nguyen, H. T. M., Nguyen, H. V., & Bui, T. T. H. (2022) · BMC Psychology · doi:10.1186/s40359-022-01003-3 · Cited by 6 · see citing works
A pilot mindfulness intervention to reduce heavy episodic drinking
Cotter, E. W., Hawthorne, D. J., Gerker, C., Norman, M., & Fotang, J. P. (2021) · Journal of College Counseling · doi:10.1002/jocc.12184 · Cited by 6 · see citing works
Is mindfulness a noticeable quality? Development and validation of the observed mindfulness measure
Bartlett, L., Martin, A. J., Bruno, R., Kilpatrick, M., Sanderson, K., & Neil, A. L. (2022) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-021-09936-6 · Cited by 6 · see citing works
Finlay, K. A., Hearn, J. H., & Chater, A. (2021) · BMC Psychology · doi:10.1186/s40359-021-00628-0 · Cited by 6 · see citing works
- Authors
- Creswell, J. D., & Lindsay, E. K.
- Affiliations
- Carnegie Mellon University (US)
- Venue
- Current Directions in Psychological Science
- Publisher
- SAGE Publications
- Published
- 2014-12
- Volume
- 23
- Issue
- 6
- Pages
- 401-407
- ISSN
- 0963-7214 (ISSN-L)
- 1467-8721
- OpenAlex
- W2120274371
- Cited by
- 543
- References
- 48
- Citations by year
- 2026: 43 · 2025: 69 · 2024: 63 · 2023: 39 · 2022: 66 · 2021: 66 · 2020: 52 · 2019: 37 · 2018: 49 · 2017: 22 · 2016: 28 · 2015: 8 · 2012: 1
- FWCI
- 22.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Directions in Psychological Science (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Health Professions › General Health Professions › Health, psychology, and well-being
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Keywords
- mindfulness training, stress buffering, stress, health outcomes, pathogenesis, inflammation, depression relapse, HIV, drug abuse
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