The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Prehospital Rapid Sequence Intubation Improves Functional Outcome for Patients With Severe Traumatic Brain Injury: A Randomized Controlled Trial
Abstract
OBJECTIVE: To determine whether paramedic rapid sequence intubation in patients with severe traumatic brain injury (TBI) improves neurologic outcomes at 6 months compared with intubation in the hospital. BACKGROUND: Severe TBI is associated with a high rate of mortality and long-term morbidity. Comatose patients with TBI routinely undergo endo-tracheal intubation to protect the airway, prevent hypoxia, and control ventilation. In many places, paramedics perform intubation prior to hospital arrival. However, it is unknown whether this approach improves outcomes. METHODS: In a prospective, randomized, controlled trial, we assigned adults with severe TBI in an urban setting to either prehospital rapid sequence intubation by paramedics or transport to a hospital emergency department for intubation by physicians. The primary outcome measure was the median extended Glasgow Outcome Scale (GOSe) score at 6 months. Secondary end-points were favorable versus unfavorable outcome at 6 months, length of intensive care and hospital stay, and survival to hospital discharge. RESULTS: A total of 312 patients with severe TBI were randomly assigned to paramedic rapid sequence intubation or hospital intubation. The success rate for paramedic intubation was 97%. At 6 months, the median GOSe score was 5 (interquartile range, 1-6) in patients intubated by paramedics compared with 3 (interquartile range, 1-6) in the patients intubated at hospital (P = 0.28).The proportion of patients with favorable outcome (GOSe, 5-8) was 80 of 157 patients (51%) in the paramedic intubation group compared with 56 of 142 patients (39%) in the hospital intubation group (risk ratio, 1.28; 95% confidence interval, 1.00-1.64; P = 0.046). There were no differences in intensive care or hospital length of stay, or in survival to hospital discharge. CONCLUSIONS: In adults with severe TBI, prehospital rapid sequence intubation by paramedics increases the rate of favorable neurologic outcome at 6 months compared with intubation in the hospital.
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Cites
The Epidemiology and Impact of Traumatic Brain Injury: A Brief Overview
Langlois, J. A., Rutland-Brown, W., & Wald, M. M. (2006) · Journal of Head Trauma Rehabilitation · doi:10.1097/00001199-200609000-00001 · Cited by 3,643
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THE ROLE OF SECONDARY BRAIN INJURY IN DETERMINING OUTCOME FROM SEVERE HEAD INJURY
Chesnut, R. M., Marshall, L. F., Klauber, M. R., Blunt, B. A., Baldwin, N., Eisenberg, H. M., Jane, J. A., Marmarou, A., & Foulkes, M. A. (1993) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-199302000-00006 · Cited by 2,189
Cooper, D. J., Myles, P. S., McDermott, F. T., Murray, L. J., Laidlaw, J., Cooper, G., Tremayne, A. B., Bernard, S. S., Ponsford, J., & for the HTS Study Investigators (2004) · JAMA · doi:10.1001/jama.291.11.1350 · Cited by 469
Self-citationAirway Management in the Emergency Department: A One-Year Study of 610 Tracheal Intubations
Sakles, J. C., Laurin, E. G., Rantapaa, A. A., & Panacek, E. A. (1998) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(98)70342-7 · Cited by 448
Davis, D. P., Hoyt, D. B., Ochs, M., Fortlage, D., Holbrook, T., Marshall, L. K., & Rosen, P. (2003) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/01.ta.0000053396.02126.cd · Cited by 374
A statewide system of trauma care in Victoria: effect on patient survival
Cameron, P. A., Gabbe, B. J., Cooper, D. J., Walker, T., Judson, R., & McNeil, J. (2008) · Medical Journal of Australia · doi:10.5694/j.1326-5377.2008.tb02176.x · Cited by 312
Self-citationDavis, D. P., Dunford, J. V., Poste, J. C., Ochs, M., Holbrook, T., Fortlage, D., Size, M. J., Kennedy, F., & Hoyt, D. B. (2004) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/01.ta.0000135503.71684.c8 · Cited by 307
Out-of-hospital endotracheal intubation and outcome after traumatic brain injury
Wang, H. E., Peitzman, A. B., Cassidy, L. D., Adelson, P. D., & Yealy, D. M. (2004) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2004.04.008 · Cited by 276
The OPALS Major Trauma Study: impact of advanced life-support on survival and morbidity
Stiell, I. G., Nesbitt, L. P., Pickett, W., Munkley, D., Spaite, D. W., Banek, J., Field, B., Luinstra-Toohey, L., Maloney, J., Dreyer, J., et al. (2008) · Canadian Medical Association Journal · doi:10.1503/cmaj.071154 · Cited by 266
Cited by
Early management of severe traumatic brain injury
Rosenfeld, J. V., Maas, A. I., Bragge, P., Morganti-Kossmann, M. C., Manley, G. T., & Gruen, R. L. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60864-2 · Cited by 558
Self-citationErythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial
Nichol, A., French, C., Little, L., Haddad, S., Presneill, J., Arabi, Y., Bailey, M., Cooper, D. J., Duranteau, J., Huet, O., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00386-4 · Cited by 272
Self-citationMayglothling, J., Duane, T. M., Gibbs, M., McCunn, M., Legome, E., Eastman, A. L., Whelan, J., & Shah, K. H. (2012) · Journal of Trauma and Acute Care Surgery · doi:10.1097/ta.0b013e31827018a5 · Cited by 200
Impact brain apnoea–a forgotten cause of cardiovascular collapse in trauma
Wilson, M. H., Hinds, J., Grier, G., Burns, B., Carley, S., & Davies, G. (2016) · Resuscitation · doi:10.1016/j.resuscitation.2016.05.007 · Cited by 59
Moderate and Severe Traumatic Brain Injury
Frattalone, A. R., & Ling, G. S. F. (2013) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2013.03.006 · Cited by 52
Metadata
- Authors
- Bernard, S. A., Nguyen, V., Cameron, P., Masci, K., Fitzgerald, M., Cooper, D. J., Walker, T., Std, B. P., Myles, P., Murray, L., David, Taylor, Smith, K., Patrick, I., Edington, J., Bacon, A., Rosenfeld, J. V., & Judson, R.
- Venue
- Annals of Surgery
- Published
- 2010-12
- Volume
- 252
- Issue
- 6
- Pages
- 959-965
- ISSN
- 0003-4932 (ISSN-L)
- OpenAlex
- W2120067680
- Cited by
- 356
- References
- 20
- FWCI
- 10.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bernard, S. A., Nguyen, V., Cameron, P., Masci, K., Fitzgerald, M., Cooper, D. J., Walker, T., Std, B. P., Myles, P., Murray, L., David, Taylor, Smith, K., Patrick, I., Edington, J., Bacon, A., Rosenfeld, J. V., & Judson, R. (2010). Prehospital Rapid Sequence Intubation Improves Functional Outcome for Patients With Severe Traumatic Brain Injury: A Randomized Controlled Trial. Annals of Surgery. https://doi.org/10.1097/sla.0b013e3181efc15f
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
