Cited by 27Abdominal vascular conditions and treatmentsGastrointestinal Bleeding Diagnosis and TreatmentIntestinal and Peritoneal Adhesions

Laparoscopic Diagnostics of Acute Bowel Ischemia Using Ultraviolet Light and Fluorescein Dye: An Experimental Study

Jiri, Paral, Alexander, Ferko, Michal, Plodr, Jan, Raupach, Dimitar, Hadzi-Nikolov, David, Dolezal, Vendelin, Chovanec·2007·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques

Abstract

Purpose The aim of the study was to show the diagnostic potential of laparoscopy using fluorescein dye and ultraviolet light in acute bowel ischemia. Materials and methods The study involved 12 domestic pigs. Under general anesthesia, the peripheral branch of the superior mesenteric artery was embolized using polyvinyl-alcohol microparticles. Two hours after the embolization, optical filters were placed into the laparoscopic set to produce ultraviolet light. Fluorescein dye was given intravenously, and the bowel was inspected. Clips were placed on the border of the ischemia that was visualized with fluorescein. Resection of the ischemic part of the bowel and anastomosis of the viable parts were carried out using laparoscopic linear cutting staplers. After 24 hours, a laparoscopic second-look procedure was carried out to verify the viability of the anastomosis. Results The method was in all cases able to recognize intestinal ischemia and reliably differentiate ischemic bowel segments from viable bowel. Microscopic analysis of the ischemic specimens showed beginning ischemic changes of the bowel tissues. Conclusions The method should be considered a valuable diagnostic procedure both for diagnostics of early stage of acute bowel ischemia and for second-look procedures.

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Crossref · 10.1097/sle.0b013e3180dc9376

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32 of 32 references verified0 citation errors · 0 not checkable

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  • Flowmetry with fluorescein dye is currently part of the accepted standard of clinical care for intraoperative assessment of bowel viability.

    “Flowmetry with fluorescein dye is currently part of the accepted standard of clinical care for intraoperative assessment of bowel viability.”

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Authors
Jiri, P., Alexander, F., Michal, P., Jan, R., Dimitar, H.-N., David, D., & Vendelin, C.
Venue
Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Published
2007-08
Volume
17
Issue
4
Pages
291-295
ISSN
1530-4515 (ISSN-L)
OpenAlex
W1981817457
Cited by
27
References
32
Citations by year
2025: 2 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 2 · 2017: 1 · 2016: 3 · 2015: 1 · 2014: 1 · 2012: 2
FWCI
1.00
Type
journal article
Language
en
Open access
closed
Locations
  • Surgical Laparoscopy Endoscopy & Percutaneous Techniques (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
  • Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
Keywords
diagnostic laparoscopy, fluorescein, ultraviolet radiation, second-look laparoscopy, bowel resection, porcine model
MeSH terms
Animals, Disease Models, Animal, Embolization, Therapeutic, Female, Fluorescent Dyes, Intestines, Ischemia, Laparoscopy, Radiography, Swine, Ultraviolet Rays, Mesenteric Artery, Superior, Fluorescein

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