The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Mechanisms of Rejection: Current Perspectives
Abstract
Rejection is the major barrier to successful transplantation. The immune response to an allograft is an ongoing dialogue between the innate and adaptive immune system that if left unchecked will lead to the rejection of transplanted cells, tissues, or organs. Activation of elements of the innate immune system, triggered as a consequence of tissue injury sustained during cell isolation or organ retrieval and ischemia reperfusion, will initiate and amplify the adaptive response. T cells require a minimum of two signals for activation, antigen recognition, and costimulation. The activation requirements of naive T cells are more stringent than those of memory T cells. Memory T cells are present in the majority of transplant recipients as a result of heterologous immunity. The majority of B cells require help from T cells to initiate antibody production. Antibodies reactive to donor human leukocyte antigen molecules, minor histocompatibility antigens, endothelial cells, RBCs, or autoantigens can trigger or contribute to rejection early and late after transplantation. Antibody-mediated rejection triggered by alloantibody binding and complement activation is recognized increasingly as a significant contribution to graft loss. Even though one component of the immune system may dominate and lead to rejection being described in short hand as T cell or antibody mediated, it is usually multifactorial resulting from the integration of multiple mechanisms. Identifying the molecular pathways that trigger tissue injury, signal transduction and rejection facilitates the identification of targets for the development of immunosuppressive drugs.
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“Nuclear and mitochondrial DNA, reactive oxygen species (ROS), and fragmented ECM components such as hyaluronic acid or fibronectin are among the most renowned DAMPs, which are released due to perturbation in the arrangement of nucleic acids within cells, transplantation imperfections such as ischemia-reperfusion, and harsh decellularization strategies, respectively [34–37].”
From Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine (2023) · cites this paper as [34]
In the citing paper
“The interaction of dECM scaffolds with the innate immune system is mainly mediated via damage-associated molecular patterns (DAMPs), danger signals released upon the cell and ECM damage during graft processing or implantation.”
From Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine (2023) · cites this paper as [34]
In the citing paper
“However, innate immunity is insufficient for graft rejection and immunological traits of the implant, and its interplay with adaptive immunity will determine its fate [34, 39, 43].”
From Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine (2023) · cites this paper as [34]
Citations
Cites
Pattern Recognition Receptors and Inflammation
Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895
Greenwald, R. J., Freeman, G. J., & Sharpe, A. H. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115611 · Cited by 2,318
Up on the tightrope: natural killer cell activation and inhibition
Lanier, L. L. (2008) · Nature Immunology · doi:10.1038/ni1581 · Cited by 1,656
Regulatory T cells in transplantation tolerance
Wood, K. J., & Sakaguchi, S. (2003) · Nature reviews. Immunology · doi:10.1038/nri1027 · Cited by 1,319
Self-citationImmune cell migration in inflammation: present and future therapeutic targets
Luster, A. D., Alon, R., & von Andrian, U. H. (2005) · Nature Immunology · doi:10.1038/ni1275 · Cited by 1,313
Neutrophil kinetics in health and disease
Summers, C., Rankin, S. M., Condliffe, A. M., Singh, N., Peters, A. M., & Chilvers, E. R. (2010) · Trends in Immunology · doi:10.1016/j.it.2010.05.006 · Cited by 1,237
The complement system in regulation of adaptive immunity
Carroll, M. C. (2004) · Nature Immunology · doi:10.1038/ni1113 · Cited by 1,035
IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo
Hara, M., Kingsley, C. I., Niimi, M., Read, S., Turvey, S. E., Bushell, A., Morris, P. J., Powrie, F. M., & Wood, K. J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.6.3789 · Cited by 765
Self-citationMolecular Heterogeneity in Acute Renal Allograft Rejection Identified by DNA Microarray Profiling
Sarwal, M., Chua, M., Kambham, N., Hsieh, S., Satterwhite, T. S., Masek, M., & Salvatierra, O. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035588 · Cited by 698
Identification of a B cell signature associated with renal transplant tolerance in humans
Newell, K. A., Asare, A. L., Kirk, A. D., Gisler, T. D., Bourcier, K., Suthanthiran, M., Burlingham, W. J., Marks, W. H., Sanz, I., Lechler, R. I., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci39933 · Cited by 676
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Kim, C. J., Romero, R. J., Chaemsaithong, P., & Kim, J.-S. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.08.041 · Cited by 530
Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine
Dzobo, K., Thomford, N. E., Senthebane, D. A., Shipanga, H., Rowe, A., Dandara, C., Pillay, M., & Motaung, K. S. (2018) · Stem Cells International · doi:10.1155/2018/2495848 · Cited by 477
Regulatory immune cells in transplantation
Wood, K. J., Bushell, A., & Hester, J. (2012) · Nature reviews. Immunology · doi:10.1038/nri3227 · Cited by 442
Self-citationKasravi, M., Ahmadi, A., Babajani, A., Mazloomnejad, R., Hatamnejad, M. R., Shariatzadeh, S., Bahrami, S., & Niknejad, H. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00348-z · Cited by 316
Immunogenicity in xenogeneic scaffold generation: Antigen removal vs. decellularization
Wong, M. L., & Griffiths, L. G. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.01.028 · Cited by 254
Griffin, M. D., Ryan, A. E., Alagesan, S., Lohan, P., Treacy, O., & Ritter, T. (2012) · Immunology and Cell Biology · doi:10.1038/icb.2012.67 · Cited by 255
Streitz, M., Miloud, T., Kapinsky, M., Reed, M. R., Magari, R. T., Geissler, E. K., Hutchinson, J. A., Vogt, K., Schlickeiser, S., Kverneland, A. H., et al. (2013) · Transplantation Research · doi:10.1186/2047-1440-2-17 · Cited by 216
Origin and Consequences of Necroinflammation
Sarhan, M., Land, W. G., Tonnus, W., Hugo, C., & Linkermann, A. (2018) · Physiological Reviews · doi:10.1152/physrev.00041.2016 · Cited by 217
Abu-Elmagd, K. M., Kosmach‐Park, B., Costa, G., Zenati, M. S., Martin, L., Koritsky, D. A., Emerling, M., Murase, N., Bond, G. J., Soltys, K. A., et al. (2012) · Annals of Surgery · doi:10.1097/sla.0b013e318265f310 · Cited by 208
Abu-Elmagd, K. M., Wu, G. S., Costa, G., Lunz, J. G., Martin, L., Koritsky, D. A., Murase, N., Irish, W. D., & Zeevi, A. (2012) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2012.04237.x · Cited by 200
From immunosuppression to tolerance
Adams, D., Fueyo, A. S., & Samuel, D. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.02.042 · Cited by 192
Transplantation and Damage-Associated Molecular Patterns (DAMPs)
Land, W. G., Agostinis, P., Gasser, S., Garg, A. D., & Linkermann, A. (2016) · American Journal of Transplantation · doi:10.1111/ajt.13963 · Cited by 171
Sivanathan, K. N., Gronthos, S., Rojas‐Canales, D. M., Thierry, B., & Coates, P. T. (2014) · Stem Cell Reviews and Reports · doi:10.1007/s12015-014-9495-2 · Cited by 157
Mesenchymal stromal cells in renal transplantation: opportunities and challenges
Casiraghi, F., Perico, N., Cortinovis, M., & Remuzzi, G. (2016) · Nature Reviews Nephrology · doi:10.1038/nrneph.2016.7 · Cited by 154
Kwun, J., Matignon, M., Manook, M., Guendouz, S., Audard, V., Kheav, V., Poullot, E., Gautreau, C., Ezekian, B., Bodez, D., et al. (2019) · Journal of the American Society of Nephrology · doi:10.1681/asn.2018121254 · Cited by 140
Engineering the Surface of Therapeutic “Living” Cells
Park, J., Andrade, B., Seo, Y., Kim, M., Zimmerman, S. C., & Kong, H. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00157 · Cited by 140
Nilsson, J., Jernryd, V., Qin, G., Paskevicius, A., Metzsch, C., Sjöberg, T., & Steen, S. (2020) · Nature Communications · doi:10.1038/s41467-020-16782-9 · Cited by 130
Heidt, S., Hester, J., Shankar, S., Friend, P. J., & Wood, K. J. (2012) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2012.04012.x · Cited by 126
Self-citationLiu, J. M.-H., Zhang, J., Zhang, X., Hlavaty, K. A., Ricci, C. F., Leonard, J. N., Shea, L. D., & Gower, R. M. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.11.065 · Cited by 119
Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity
Mac, Q. D., Mathews, D., Kahla, J. A., Stoffers, C. M., Delmas, O. M., Holt, B. A., Adams, A. B., & Kwong, G. A. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0358-7 · Cited by 121
Li, X., Li, J., Yang, J., Wang, D., Zhao, W., Song, W., Li, W., Wang, J.-F., Han, W., Zhang, Z., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044045 · Cited by 118
Dixit, S., Baganizi, D. R., Sahu, R., Dosunmu, E., Chaudhari, A. A., Vig, K., Pillai, S., Singh, S. R., & Dennis, V. A. (2017) · Journal of Biological Engineering · doi:10.1186/s13036-017-0089-9 · Cited by 128
Arzi, B., Clark, K. C., Sundaram, A., Spriet, M. P., Verstraete, F. J. Μ., Walker, N. J., Loscar, M. R., Fazel, N., Murphy, W. J., Vapniarsky, N., et al. (2017) · Stem Cells Translational Medicine · doi:10.1002/sctm.17-0035 · Cited by 114
Allogeneic CAR-T Therapy Technologies: Has the Promise Been Met?
Lonez, C., & Breman, E. (2024) · Cells · doi:10.3390/cells13020146 · Cited by 119
Mesenchymal Stromal Cells in Transplantation Rejection and TolerancePreprint
English, K., & Wood, K. J. (2013) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a015560 · Cited by 98
Self-citationMescher, A. L., Neff, A. W., & King, M. W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080477 · Cited by 85
Non-invasive Biomarkers of Acute Rejection in Kidney Transplantation: Novel Targets and Strategies
Eikmans, M., Gielis, E. M., Ledeganck, K. J., Yang, J., Abramowicz, D., & Claas, F. H. J. (2019) · Frontiers in Medicine · doi:10.3389/fmed.2018.00358 · Cited by 91
Three dimensional printed nanostructure biomaterials for bone tissue engineering
Marew, T., & Birhanu, G. (2021) · Regenerative Therapy · doi:10.1016/j.reth.2021.05.001 · Cited by 83
Kinnear, G., Jones, N. D., & Wood, K. J. (2012) · Transplantation · doi:10.1097/tp.0b013e31826d4672 · Cited by 82
Self-citationMesenchymal Stromal Cells for Transplant Tolerance
Podestà, M. A., Remuzzi, G., & Casiraghi, F. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01287 · Cited by 83
Sarhane, K. A., TUFFAHA, S. H., Broyles, J. M., Ibrahim, A. E., Khalifian, S., Baltodano, P. A., Santiago, G. F., Alrakan, M., & Ibrahim, Z. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00406 · Cited by 81
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Alelign, T., Ahmed, M. M., Bobosha, K., Tadesse, Y., Howe, R., & Petros, B. (2018) · Journal of Immunology Research · doi:10.1155/2018/5986740 · Cited by 82
Gower, R. M., Boehler, R. M., Azarin, S. M., Ricci, C. F., Leonard, J. N., & Shea, L. D. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.11.036 · Cited by 78
Immunogenicity of Allogeneic Mesenchymal Stromal Cells: What Has Been Seen in Vitro and in Vivo ?
Consentius, C., Reinke, P., & Volk, H. (2015) · Regenerative Medicine · doi:10.2217/rme.15.14 · Cited by 78
Ono, M., Oshima, M., Ogawa, M., Sonoyama, W., Hara, E. S., Oida, Y., Shinkawa, S., Nakajima, R., Mine, A., Hayano, S., et al. (2017) · Scientific Reports · doi:10.1038/srep44522 · Cited by 76
Lohan, P., Coleman, C. M., Murphy, M. J., Griffin, M. D., Ritter, T., & Ryan, A. E. (2014) · Stem Cell Research & Therapy · doi:10.1186/scrt488 · Cited by 76
mTOR inhibitors effects on regulatory T cells and on dendritic cells
Stallone, G., Infante, B., Lorenzo, A. D., Rascio, F., Zaza, G., & Grandaliano, G. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-0916-7 · Cited by 76
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Kraaij, M. D., Vereyken, E. J. F., Leenen, P. J. M., van den Bosch, T. P. P., Rezaee, F., Betjes, M. G. H., Baan, C. C., & Rowshani, A. T. (2014) · Cytokine · doi:10.1016/j.cyto.2014.02.001 · Cited by 71
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Bhagra, S. K., Pettit, S., & Parameshwar, J. K. (2018) · Heart · doi:10.1136/heartjnl-2018-313103 · Cited by 70
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Romero, R. J., Chaemsaithong, P., Chaiyasit, N., Docheva, N., Dong, Z., Kim, C. J., Kim, Y. M., Kim, J.-S., Qureshi, F., Jacques, S. M., et al. (2017) · American Journal of Reproductive Immunology · doi:10.1111/aji.12685 · Cited by 71
Figueiredo, C., Oliveira, M. C., Chen, C., Jansson, K., Höffler, K., Yuzefovych, Y., Pogozhykh, O., Jin, Z., Kühnel, M., Jonigk, D. D., et al. (2018) · Human Gene Therapy · doi:10.1089/hum.2018.117 · Cited by 69
IL-34 Inhibits Acute Rejection of Rat Liver Transplantation by Inducing Kupffer Cell M2 Polarization
Zhao, Z., Pan, G., Tang, C., Li, Z., Zheng, D., Wei, X., & Wu, Z. (2018) · Transplantation · doi:10.1097/tp.0000000000002194 · Cited by 67
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Karahan, G. E., Claas, F. H. J., & Heidt, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00686 · Cited by 69
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Effect of Angiogenesis in Bone Tissue Engineering
Huang, J., Han, Q., Cai, M., Zhu, J., Li, L., Yu, L., Wang, Z., Fan, G., Zhu, Y., Lü, J., et al. (2022) · Annals of Biomedical Engineering · doi:10.1007/s10439-022-02970-9 · Cited by 64
Li, L., Wang, R., Jia, Y., Rong, R., Xu, M., & Zhu, T. (2019) · Frontiers in Medicine · doi:10.3389/fmed.2019.00269 · Cited by 60
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Drachenberg, C. B., & Papadimitriou, J. C. (2013) · Transplantation · doi:10.1097/tp.0b013e31827e6b45 · Cited by 60
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Tang, Q., Dong, C., & Sun, Q. (2022) · Inflammation Research · doi:10.1007/s00011-022-01651-6 · Cited by 59
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Wood, K. J., Issa, F., & Hester, J. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.11.005 · Cited by 59
Self-citationNaji, A., Rouas‐Freiss, N., Dürrbach, A., Carosella, E. D., Sensebé, L., & Deschaseaux, F. (2013) · Stem Cells · doi:10.1002/stem.1494 · Cited by 58
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Mesnard, L., Muthukumar, T., Burbach, M., Li, C. Y., Shang, H., Dadhania, D. M., Lee, J. R., Sharma, V. K., Xiang, J., Suberbielle, C., et al. (2016) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005088 · Cited by 64
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Cozzi, E., Colpo, A., & De Silvestro, G. (2017) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2017.07.005 · Cited by 57
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Stolp, J., Turka, L. A., & Wood, K. J. (2014) · Nature Reviews Nephrology · doi:10.1038/nrneph.2014.80 · Cited by 61
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Elsabbagh, A. M., Hawksworth, J. S., Khan, K., Kaufman, S. S., Yazigi, N. A., Kroemer, A., Smith, C. I., Fishbein, T., & Matsumoto, C. (2019) · American Journal of Transplantation · doi:10.1111/ajt.15269 · Cited by 56
Freeley, M., & Long, A. (2013) · Biochemical Journal · doi:10.1042/bj20130950 · Cited by 55
Dollinger, B. R., Gupta, M. K., Martin, J. R., & Duvall, C. L. (2017) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0495 · Cited by 51
Kanitakis, J., Karayannopoulou, G., Lanzetta, M., & Petruzzo, P. (2014) · Transplant International · doi:10.1111/tri.12399 · Cited by 50
Supplemental mineral ions for bone regeneration and osteoporosis treatment
Su, Y., Cappock, M., Dobres, S., Kucine, A. J., Waltzer, W. C., & Zhu, D. (2023) · Engineered Regeneration · doi:10.1016/j.engreg.2023.02.003 · Cited by 54
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Etra, J. W., Raimondi, G., & Brandacher, G. (2017) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000490 · Cited by 49
Chandrasekharan, D. P., Issa, F., & Wood, K. J. (2013) · Transplant International · doi:10.1111/tri.12081 · Cited by 49
Self-citationLei, T., Chen, L., Wang, K., Du, S., Gonelle‐Gispert, C., Wang, Y., & Bühler, L. H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1031185 · Cited by 44
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Stolp, J., Zaitsu, M., & Wood, K. J. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-8938-6_12 · Cited by 44
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Hoffmann, U., Neudörfl, C., Daemen, K., Keil, J., Stevanovic-Meyer, M., Lehner, F., Haller, H. G., Blume, C. A., & Falk, C. S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132484 · Cited by 44
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Goto, R., You, S., Zaitsu, M., Chatenoud, L., & Wood, K. J. (2013) · American Journal of Transplantation · doi:10.1111/ajt.12272 · Cited by 42
Self-citationGraft microvascular disease in solid organ transplantation
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Gajardo, T., Morales, R. A., Campos‐Mora, M., Campos‐Acuña, J., & Pino‐Lagos, K. (2015) · Immunology · doi:10.1111/imm.12483 · Cited by 41
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Gu, H., Xie, M., Xu, L., Zheng, X., Yang, Y., & Lv, X. (2015) · Transplant International · doi:10.1111/tri.12683 · Cited by 40
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Cantarelli, E., Citro, A., Marzorati, S., Melzi, R., Scavini, M., & Piemonti, L. (2013) · Islets · doi:10.4161/isl.24698 · Cited by 40
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Self-citationPonticelli, C. E., & Campise, M. (2021) · Kidney International · doi:10.1016/j.kint.2021.04.016 · Cited by 42
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Yuan, J., Bagley, J., & Iacomini, J. (2015) · American Journal of Transplantation · doi:10.1111/ajt.13350 · Cited by 37
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Self-citationFindeisen, K., Morticelli, L., Goecke, T., Kolbeck, L., Ramm, R., Höffler, H., Brandes, G., Korossis, S., Haverich, A., & Hilfiker, A. (2020) · Xenotransplantation · doi:10.1111/xen.12617 · Cited by 36
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Borges, T. J., O’Malley, J. T., Wo, L. M., Murakami, N., Smith, B., Azzi, J. R., Tripathi, S., Lane, J. D., Bueno, E. M., Clark, R. A., et al. (2016) · American Journal of Transplantation · doi:10.1111/ajt.13705 · Cited by 35
Thaunat, O., Badet, L., Dubois, V., Kanitakis, J., Petruzzo, P., & Morélon, E. (2015) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000242 · Cited by 35
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Heim, C., Gebhardt, J., Ramsperger-Gleixner, M., Jacobi, J., Weyand, M., & Ensminger, S. M. (2015) · Heart and Vessels · doi:10.1007/s00380-015-0696-7 · Cited by 35
Vereyken, E. J. F., Kraaij, M. D., Baan, C. C., Rezaee, F., Weimar, W., Wood, K. J., Leenen, P. J. M., & Rowshani, A. T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070152 · Cited by 33
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Issa, F., & Wood, K. J. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00254 · Cited by 33
Self-citationHeidt, S., Vergunst, M., Anholts, J. D. H., Reinders, M. E. J., de Fijter, J. W., Eikmans, M., & Claas, F. H. J. (2014) · Transplantation · doi:10.1097/tp.0000000000000465 · Cited by 33
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Metadata
- Authors
- Wood, K. J., & Goto, R.
- Affiliations
- John Radcliffe Hospital (GB)
- Corresponding author
- Wood, Kathryn J.
- ORCID
- Goto, Ryoichi
- Venue
- Transplantation
- Published
- 2012-01-15
- Volume
- 93
- Issue
- 1
- Pages
- 1-10
- ISSN
- 0041-1337 (ISSN-L)
- OpenAlex
- W1973175840
- Cited by
- 369
- References
- 65
- Citations by year
- 2026: 12 · 2025: 14 · 2024: 18 · 2023: 19 · 2022: 14 · 2021: 22 · 2020: 25 · 2019: 24 · 2018: 27 · 2017: 27 · 2016: 25 · 2015: 36 · 2014: 43 · 2013: 32 · 2012: 31
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Transplantation (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- British Heart Foundation
- Topics
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Health Sciences › Medicine › Transplantation › Renal Transplantation Outcomes and Treatments
- Keywords
- graft rejection, innate immune activation, adaptive immune response, T cell activation, costimulation, memory T cells, heterologous immunity, B cell help, antibody-mediated rejection, alloantibodies, complement activation, minor histocompatibility antigens, HLA antibodies, ischemia-reperfusion injury, graft loss
- MeSH terms
- B-Lymphocytes, Graft Rejection, Humans, Immunity, Innate, T-Lymphocytes, Signal Transduction, Organ Transplantation
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