Cited by 45Attention Deficit Hyperactivity DisorderDementia and Cognitive Impairment ResearchSchizophrenia research and treatment

When does it end? Attention-deficit/hyperactivity disorder in the middle aged and older populations

Manor, Iris, Rozen, Shlomit, Zemishlani, Zvi, Weizman, Abraham, Zalsman, Gil·2011·Clinical Neuropharmacology

Abstract

Background Attention-deficit/hyperactivity disorder (ADHD) is estimated to affect 4% to 6% of the adult population. In recent years, more and more middle-aged and older adults (>55 years) turn to the ADHD unit at Geha Mental Health Center suspecting ADHD. Yet, a literature search resulted in very few relevant studies. Methods and results This study, approved by the Geha Mental Health Center ethics committee, presents 11 patients, 55 years or older, diagnosed and treated by the unit. The patients underwent complete clinical evaluation for ADHD according to Diagnostic and Statistical Manual of Mental Disorder, Fourth Edition. The data-collection phase included demographic and clinical data; Test of Variables of Attention scores used as indicators of methylphenidate (MPH) response; Clinical Global Impression scores of both severity and improvement were used. Because the sample is very small, allowing only limited statistical analyses, nonparametric statistics were used. Eleven patients, aged 61.64 ± 3.87 years (male-female ratio, 9:2), were assessed. The follow-up was conducted for more than 2 months. Fifty-five percent had ADHD, predominantly inattentive, and 45% had ADHD combined type. All patients indicated suffering (Clinical Global Impression-Severity score range: mild = 27.3%, moderate = 45.4%, severe = 27.3%). Fifty-four percent showed at least 1 psychiatric comorbidity. Test of Variables of Attention scores showed significant improvement in 90% (8/9 patients) with MPH do…

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Crossref · 10.1097/wnf.0b013e3182206dc1

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Authors
Manor, I., Rozen, S., Zemishlani, Z., Weizman, A., & Zalsman, G.
Affiliations
  • Tel Aviv University (IL)
  • Geha Mental Health Center (IL)
Corresponding author
  • Manor, Iris
  • Rozen, Shlomit
  • Weizman, Abraham
  • Zalsman, Gil
Venue
Clinical Neuropharmacology
Published
2011-07
Volume
34
Issue
4
Pages
148-154
ISSN
0362-5664 (ISSN-L)
OpenAlex
W1975867705
Cited by
45
References
5
Citations by year
2025: 1 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 6 · 2019: 3 · 2018: 1 · 2017: 4 · 2016: 4 · 2015: 3 · 2014: 4 · 2013: 6 · 2012: 3
FWCI
2.84
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Neuropharmacology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Keywords
adult ADHD, middle-aged and older adults, methylphenidate response, Test of Variables of Attention, inattentive type ADHD, combined type ADHD, psychiatric comorbidity, medication adherence, adverse effects, clinical global impression
MeSH terms
Aged, Aging, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Female, Follow-Up Studies, Hospitals, Psychiatric, Humans, Israel, Male, Medical Records, Methylphenidate, Middle Aged, Pilot Projects, Psychiatric Status Rating Scales, Retrospective Studies, Comorbidity, Diagnostic and Statistical Manual of Mental Disorders

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