When does it end? Attention-deficit/hyperactivity disorder in the middle aged and older populations
Abstract
Background Attention-deficit/hyperactivity disorder (ADHD) is estimated to affect 4% to 6% of the adult population. In recent years, more and more middle-aged and older adults (>55 years) turn to the ADHD unit at Geha Mental Health Center suspecting ADHD. Yet, a literature search resulted in very few relevant studies. Methods and results This study, approved by the Geha Mental Health Center ethics committee, presents 11 patients, 55 years or older, diagnosed and treated by the unit. The patients underwent complete clinical evaluation for ADHD according to Diagnostic and Statistical Manual of Mental Disorder, Fourth Edition. The data-collection phase included demographic and clinical data; Test of Variables of Attention scores used as indicators of methylphenidate (MPH) response; Clinical Global Impression scores of both severity and improvement were used. Because the sample is very small, allowing only limited statistical analyses, nonparametric statistics were used. Eleven patients, aged 61.64 ± 3.87 years (male-female ratio, 9:2), were assessed. The follow-up was conducted for more than 2 months. Fifty-five percent had ADHD, predominantly inattentive, and 45% had ADHD combined type. All patients indicated suffering (Clinical Global Impression-Severity score range: mild = 27.3%, moderate = 45.4%, severe = 27.3%). Fifty-four percent showed at least 1 psychiatric comorbidity. Test of Variables of Attention scores showed significant improvement in 90% (8/9 patients) with MPH do…
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Older adults have been reported to benefit from pharmacological treatment similarly to younger adults.
“Older adults have been reported to have similar benefits from pharmacological treatment as younger adults (Lensing et al., 2015;Manor et al., 2011)”
From Prevalence of attention-deficit/hyperactivity disorder in older adults: a systematic review and meta-analysis (2020) · cites this paper as Manor et al., 2011
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“This seems to be a not uncommon phenomenon in younger adult populations, according to literature.(16) Six (55%) had other medical problems, which may be expected in this age group (hypertension, type 2 diabetes, and ischemic heart disease), although the percentage was relatively high.”
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“The appropriate treatment includes psychotherapy and pharmacotherapy, with the latter consisting mainly of stimulants, especially methylphenidate (MPH).(9,10) There are, however, few data available on ADHD in the middle-aged and older population.”
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- Authors
- Manor, I., Rozen, S., Zemishlani, Z., Weizman, A., & Zalsman, G.
- Affiliations
- Tel Aviv University (IL)
- Geha Mental Health Center (IL)
- Corresponding author
- Manor, Iris
- Rozen, Shlomit
- Weizman, Abraham
- Zalsman, Gil
- Venue
- Clinical Neuropharmacology
- Published
- 2011-07
- Volume
- 34
- Issue
- 4
- Pages
- 148-154
- ISSN
- 0362-5664 (ISSN-L)
- OpenAlex
- W1975867705
- Cited by
- 45
- References
- 5
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 6 · 2019: 3 · 2018: 1 · 2017: 4 · 2016: 4 · 2015: 3 · 2014: 4 · 2013: 6 · 2012: 3
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Neuropharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- adult ADHD, middle-aged and older adults, methylphenidate response, Test of Variables of Attention, inattentive type ADHD, combined type ADHD, psychiatric comorbidity, medication adherence, adverse effects, clinical global impression
- MeSH terms
- Aged, Aging, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Female, Follow-Up Studies, Hospitals, Psychiatric, Humans, Israel, Male, Medical Records, Methylphenidate, Middle Aged, Pilot Projects, Psychiatric Status Rating Scales, Retrospective Studies, Comorbidity, Diagnostic and Statistical Manual of Mental Disorders
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