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Citalopram modulation of neuronal responses to aversive face emotions: a functional MRI study
Abstract
This study investigated the serotonergic modulation of face emotion processing using blood oxygen level-dependent (BOLD) functional MRI. In a placebo-controlled, balanced order design, intravenous citalopram (7.5 mg) was given to 12 male volunteers 60 min before a covert face emotion recognition task. Angry, disgusted and fearful faces produced BOLD signal responses, which were broadly consistent with previous findings. Citalopram enhanced the BOLD signal response in the left posterior insula (together with nonprespecified pulvinar and visual cortex) but attenuated activation in the left amygdala to disgusted faces and right amygdala activation to fearful faces. No citalopram modulation of BOLD responses to angry faces were found. These results suggest that serotonin modulates low-level amygdala activation to aversive stimuli.
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“Studies acutely enhancing 5-HT function with citalopram have found decreased amygdala responses to negative compared with neutral faces (Anderson et al., 2007;Del-Ben et al., 2005;Murphy et al., 2009a) but increased activation comparing faces (emotional and neutral) and a sensorimotor control task (Bigos et al., 2008).”
From Affective Cognition and its Disruption in Mood Disorders (2011) · cites this paper as Anderson et al., 2007
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Cites
Ekman, P. (1976) · Medical Entomology and Zoology · Cited by 4,345
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173
Why sex matters for neuroscience
Cahill, L. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1909 · Cited by 1,540
Sheline, Y. I., Barch, D. M., Donnelly, J. M., Ollinger, J. M., Snyder, A. Z., & Mintun, M. A. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01263-x · Cited by 1,191
The Amygdala Response to Emotional Stimuli: A Comparison of Faces and Scenes
Hariri, A. R., Tessitore, A., Mattay, V. S., Fera, F., & Weinberger, D. R. (2002) · NeuroImage · doi:10.1006/nimg.2002.1179 · Cited by 984
Fu, C. H. Y., Williams, S. C. R., Cleare, A. J., Brammer, M. J., Walsh, N. D., Kim, J., Andrew, C. M., Pich, E. M., Williams, P. M., Reed, L. J., et al. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.9.877 · Cited by 775
Self-citationWhat is the function of the claustrum?
Crick, F. C., & Koch, C. (2005) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2005.1661 · Cited by 742
Dissociable Neural Responses in Human Reward Systems
Elliott, R., Friston, K. J., & Dolan, R. J. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-16-06159.2000 · Cited by 740
Self-citationAntidepressant Drug Treatment Modifies the Neural Processing of Nonconscious Threat Cues
Harmer, C. J., Mackay, C. E., Reid, C. B., Cowen, P. J., & Goodwin, G. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.015 · Cited by 450
Beyond threat: amygdala reactivity across multiple expressions of facial affect
Fitzgerald, D. A., Angstadt, M., Jelsone, L. M., Nathan, P. J., & Phan, K. L. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.11.003 · Cited by 427
Facial expressions and complex IAPS pictures: Common and differential networks
Britton, J. C., Taylor, S. F., Sudheimer, K. D., & Liberzon, I. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.12.050 · Cited by 425
Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers
Harmer, C. J., Bhagwagar, Z., Perrett, D. I., Völlm, B. A., Cowen, P. J., & Goodwin, G. M. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300004 · Cited by 420 · cited 2×
“This appears inconsistent with behavioural studies, which have suggested 5-HT positively modulates recognition of fearful faces in women [3,4].”
BackgroundResultPhillips, M. L., Williams, L. M., Heining, M., Herba, C. M., Russell, T., Andrew, C., Bullmore, E. T., Brammer, M. J., Williams, S. C. R., Morgan, M., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.12.013 · Cited by 314
Self-citationDel-Ben, C. M., Deakin, J. F. W., Mckie, S., Delvai, N. A., Williams, S. R., Elliott, R., Dolan, M., & Anderson, I. M. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300728 · Cited by 260
Self-citationProcessing Faces and Facial Expressions
Posamentier, M. T., & Abdi, H. (2003) · Neuropsychology Review · doi:10.1023/a:1025519712569 · Cited by 257
Shelley, B. P., & Trimble, M. (2004) · The World Journal of Biological Psychiatry · doi:10.1080/15622970410029933 · Cited by 172
Tryptophan depletion decreases the recognition of fear in female volunteers
Harmer, C. J., Rogers, R. D., Tunbridge, E. M., Cowen, P. J., & Goodwin, G. M. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1401-6 · Cited by 165
Cools, R., Calder, A. J., Lawrence, A. D., Clark, L., Bullmore, E., & Robbins, T. W. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2215-5 · Cited by 161
Neuronal effects of acute citalopram detected by pharmacoMRI
McKie, S., Del‐Ben, C. M., Elliott, R., Williams, S., del Vai, N., Anderson, I. M., & Deakin, J. F. W. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2270-y · Cited by 123
Self-citationFunctional dissociation of amygdala-modulated arousal and cognitive appraisal, in Turner syndrome
Skuse, D., Morris, J. S., & Dolan, R. J. (2005) · Brain · doi:10.1093/brain/awh562 · Cited by 85
The role of serotonin in panic, anxiety and depression
Deakin, J. F. W. (1998) · International Clinical Psychopharmacology · doi:10.1097/00004850-199804004-00001 · Cited by 81
Worsley (1996) · doi:10.1002/(sici)1097-0193(1996)4:1
Research works printed but not linked: 1
- First, 2002, Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition (SCID-I/NP)
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Roiser, J. P., Elliott, R., & Sahakian, B. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.183 · Cited by 535
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Metadata
- Authors
- Anderson, I. M., Del-Ben, C. M., Mckie, S., Richardson, P., Williams, S. R., Elliott, R., & William Deakin, J. F.
- Affiliations
- University of Manchester (GB)
- Sheffield Hallam University (GB)
- Corresponding author
- Anderson, Ian M.
- Venue
- NeuroReport
- Published
- 2007-08-27
- Volume
- 18
- Issue
- 13
- Pages
- 1351-1355
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W1984163458
- Cited by
- 129
- References
- 22
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 4 · 2023: 3 · 2022: 4 · 2021: 5 · 2020: 5 · 2019: 5 · 2018: 6 · 2017: 2 · 2016: 4 · 2015: 14 · 2014: 6 · 2013: 9 · 2012: 8
- FWCI
- 5.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroreport (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- citalopram, serotonin, aversive emotions, amygdala, posterior insula, disgust, fear, anger, facial emotion recognition, serotonergic modulation
- MeSH terms
- Adult, Brain, Brain Mapping, Emotions, Face, Humans, Image Processing, Computer-Assisted, Functional Laterality, Magnetic Resonance Imaging, Male, Oxygen, Pattern Recognition, Visual, Photic Stimulation, Citalopram, Single-Blind Method, Antidepressive Agents, Second-Generation
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