The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
The decision neuroscience perspective on suicidal behavior: evidence and hypotheses
Open accessAbstract
PURPOSE OF REVIEW: Suicide attempts are usually regretted by people who survive them. Furthermore, addiction and gambling are over-represented among people who attempt or die by suicide, raising the question whether their decision-making is impaired. Advances in decision neuroscience have enabled us to investigate decision processes in suicidal people and to elucidate putative neural substrates of disadvantageous decision-making. RECENT FINDINGS: Early studies have linked attempted suicide to poor performance on gambling tasks. More recently, functional MRI augmented with a reinforcement learning computational model revealed that impaired decision-making in suicide attempters is paralleled by disrupted expected value (expected reward) signals in the ventromedial prefrontal cortex. Behavioral studies have linked increased delay discounting to low-lethality/poorly planned attempts, multiple attempts, and the co-occurrence of attempted suicide and addiction. This behavioral tendency may be related to altered integrity of the basal ganglia. By contrast, well-planned, serious suicide attempts were associated with intact/diminished delay discounting. One study has linked high-lethality suicide attempts and impaired social decision-making. SUMMARY: This emerging literature supports the notion that various impairments in decision-making - often broadly related to impulsivity - may mark different pathways to suicide. We propose that aggressive and self-destructive responses to social stressors in people prone to suicide result from a predominance of automatic, Pavlovian processes over goal-directed computations.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“For instance, depressed patients exhibit both hyposensitivity to rewards and oversensitivity to punishments 96,97 , attributed to alterations in mesolimbic prediction error signaling 97-99 , and may exhibit a constrained option space ('tunnel vision') during decision-making 100 .”
From Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model (2020) · cites this paper as [100]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The interpersonal theory of suicide.
Van Orden, K. A., Witte, T. K., Cukrowicz, K. C., Braithwaite, S. R., Selby, E. A., & Joiner, T. E. (2010) · Psychological Review · doi:10.1037/a0018697 · Cited by 5,292
Bartra, O., McGuire, J. T., & Kable, J. W. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.02.063 · Cited by 1,927
Baumeister, R. F. (1990) · Psychological Review · doi:10.1037/0033-295x.97.1.90 · Cited by 1,919 · cited 1×
“All rights rese Modern accounts of suicide such as Williams’ entrapment theory [4] and Baumeister’s view of suicide as an escape from the aversive self [5], see it as a flight from irresolvable problems.”
BackgroundThe neural correlates of subjective value during intertemporal choice
Kable, J. W., & Glimcher, P. W. (2007) · Nature Neuroscience · doi:10.1038/nn2007 · Cited by 1,916
Frames, Biases, and Rational Decision-Making in the Human Brain
de Martino, B., Kumaran, D., Seymour, B., & Dolan, R. (2006) · Science · doi:10.1126/science.1128356 · Cited by 1,623
Goal-directed instrumental action: contingency and incentive learning and their cortical substrates
Balleine, B. W., & Dickinson, A. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00033-1 · Cited by 1,541
Van Orden, K. A., Witte, T. K., Gordon, K. H., Bender, T. W., & Joiner, T. E. (2008) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.76.1.72 · Cited by 1,126
Delayed reward discounting and addictive behavior: a meta-analysis
MacKillop, J., Amlung, M. T., Few, L. R., Ray, L. A., Sweet, L. H., & Munafò, M. R. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2229-0 · Cited by 1,021
The Hyperbolic Consumption Model: Calibration, Simulation, and Empirical Evaluation
Angeletos, G.-M., Laibson, D., Repetto, A., Tobacman, J., & Weinberg, S. (2001) · The Journal of Economic Perspectives · doi:10.1257/jep.15.3.47 · Cited by 1,001
Motivational control of goal-directed action
Dickinson, A., & Balleine, B. (1994) · Animal Learning & Behavior · doi:10.3758/bf03199951 · Cited by 995
Flagged first, then by citations
Cited by
Sorted by citations
Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model
Price, R. B., & Duman, R. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0615-x · Cited by 739
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Schmaal, L., van Harmelen, A.-L., Chatzi, V., Lippard, E. T. C., Toenders, Y. J., Averill, L. A., Mazure, C. M., & Blumberg, H. P. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0587-x · Cited by 373
A brain-centric model of suicidal behavior
Mann, J. J., & Rizk, M. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20081224 · Cited by 214
Kim, K., Kim, S.-W., Myung, W., Han, C. E., Fava, M., Mischoulon, D., Papakostas, G. I., Seo, S. W., Cho, H., Seong, J.-K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-15926-0 · Cited by 107
Jollant, F., Wagner, G., Richard-Devantoy, S., Köhler, S., Bär, K.-J., Turecki, G., & Pereira, F. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0170-2 · Cited by 54
Metadata
- Authors
- Dombrovski, A. Y., & Hallquist, M. N.
- Affiliations
- Pennsylvania State University (US)
- Corresponding author
- Dombrovski, Alexandre Y.
- Venue
- Current Opinion in Psychiatry
- Published
- 2017-01
- Volume
- 30
- Issue
- 1
- Pages
- 7-14
- ISSN
- 0951-7367 (ISSN-L)
- PMC
- PMC5291285
- OpenAlex
- W2553902797
- Cited by
- 91
- References
- 82
- Citations by year
- 2026: 2 · 2025: 14 · 2024: 12 · 2023: 12 · 2022: 9 · 2021: 11 · 2020: 10 · 2019: 11 · 2018: 7 · 2017: 3
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Current Opinion in Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R01MH100095, K01MH097091, K23MH086620, R03MH090791, R01MH124092, R01MH085651)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
- Keywords
- suicidal behavior, suicide attempts, decision-making impairment, impulsivity, delay discounting, gambling behavior, addiction, ventromedial prefrontal cortex, basal ganglia, social decision-making, reinforcement learning
- MeSH terms
- Decision Making, Humans, Suicide, Attempted
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
