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Cited by 5Psychopathy, Forensic Psychiatry, Sexual OffendingNeurotransmitter Receptor Influence on BehaviorNeuroendocrine regulation and behavior

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Possible association between the prolactin receptor gene and callous-unemotional traits among aggressive children

Hirata, Yuko, Zai, Clement C., Nowrouzi, Behdin, Shaikh, Sajid A., Kennedy, James L., Beitchman, Joe H.·2016·Psychiatric Genetics
DOI 10.1097/ypg.0000000000000108
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Abstract

This study examined the possible association between prolactin (PRL) system genes and callous-unemotional (CU) traits in childhood-onset aggression. Two markers for the PRL peptide gene and three markers for the prolactin receptor (PRLR) gene were genotyped. The participants were assessed on the CU subscale using five items from the Antisocial Process Screening Device. Genotype analysis showed nominally significant results with PRLR_rs187490 (uncorrected P=0.01), with the GG genotype associated with higher CU scores. This is the first paper to evaluate the relationship of PRL system genes with CU traits in childhood-onset aggression.

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Crossref · 10.1097/ypg.0000000000000108

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Metadata

Authors
Hirata, Y., Zai, C. C., Nowrouzi, B., Shaikh, S. A., Kennedy, J. L., & Beitchman, J. H.
Affiliations
Centre for Addiction and Mental Health (CA)
Corresponding author
Kennedy, James L.
ORCID
Venue
Psychiatric Genetics
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2016-02
Volume
26
Issue
1
Pages
48-51
ISSN
0955-8829 (ISSN-L)
DOI
10.1097/ypg.0000000000000108
OpenAlex
W2339074466
Cited by
5
References
35
Citations by year
2025: 1 · 2024: 1 · 2019: 2 · 2017: 1
FWCI
0.41
Type
journal article
Language
en
Open access
closed
Locations
  • Psychiatric Genetics (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • American Foundation for Suicide Prevention
  • Centre for Addiction and Mental Health
  • Centre for Addiction and Mental Health Foundation
  • Eli Lilly Canada
Topics
  • Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Keywords
prolactin receptor gene, callous-unemotional traits, antisocial behavior, genetic association, Antisocial Process Screening Device
MeSH terms
Adolescent, Aggression, Antisocial Personality Disorder, Child, Emotions, Female, Humans, Male, Receptors, Prolactin, Polymorphism, Single Nucleotide, Genetic Association Studies

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