Zai, Clement C.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., et al. (2017) · Nature Genetics

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 1,058

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 544

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 270

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J., Murnyak, B., Wendt, F., Adams, M., et al. (2023) · American Journal of Psychiatry

Genetic Associations and EpidemiologySuicide and Self-Harm Studies

Cited by 160

The role of oxytocin and oxytocin receptor gene variants in childhood‐onset aggression

Malik, A. I., Zai, C. C., Abu, Z., Nowrouzi, B., & Beitchman, J. H. (2012) · Genes, Brain and Behavior

Neuroendocrine regulation and behaviorPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 128

Dopaminergic system genes in childhood aggression: Possible role for DRD2

Zai, C. C., Ehtesham, S., Choi, E., Nowrouzi, B., de Luca, V., Stankovich, L., Davidge, K., Freeman, N., King, N., Kennedy, J. L., et al. (2012) · The World Journal of Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 78

Study of the Catechol‐O‐Methyltransferase (COMT) Gene with High Aggression in Children

Hirata, Y., Zai, C. C., Nowrouzi, B., Beitchman, J. H., & Kennedy, J. L. (2013) · Aggressive Behavior

Psychopathy, Forensic Psychiatry, Sexual OffendingNeurotransmitter Receptor Influence on Behavior

Cited by 65

Antipsychotics, dopamine D₂ receptor occupancy and clinical improvement in schizophrenia: a meta-analysis

Yilmaz, Z., Zai, C. C., Hwang, R., Mann, S., Arenovich, T., Remington, G., & Daskalakis, Z. J. (2012) · Schizophrenia Research

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 52

Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice

Lee, F. H., Zai, C. C., Cordes, S. P., Roder, J. C., & Wong, A. H. (2013) · Molecular Brain

Schizophrenia research and treatmentNeurogenesis and neuroplasticity mechanisms

Cited by 49

Possible genetic association between vasopressin receptor 1B and child aggression

Zai, C. C., Muir, K. E., Nowrouzi, B., Shaikh, S. A., Choi, E., Berall, L., Trépanier, M.-O., Beitchman, J. H., & Kennedy, J. L. (2012) · Psychiatry Research

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 43

Genetics of child aggression, a systematic review

Koyama, E., Kant, T., Takata, A., Kennedy, J. L., & Zai, C. C. (2024) · Translational Psychiatry

Neurotransmitter Receptor Influence on BehaviorPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 33

Epigenome-wide association study of suicide attempt in schizophrenia

Bani-Fatemi, A., Jeremian, R., Wang, K. Z., Silveira, J., Zai, C., Kolla, N. J., Graff, A., Gerretsen, P., Strauss, J., & De Luca, V. (2018) · Journal of Psychiatric Research

Epigenetics and DNA MethylationSuicide and Self-Harm Studies

Cited by 33

The role of genetic variants in genes regulating the oxytocin–vasopressin neurohumoral system in childhood-onset aggression

Malik, A. I., Zai, C. C., Berall, L., Abu, Z., Din, F., Nowrouzi, B., Chen, S., & Beitchman, J. H. (2014) · Psychiatric Genetics

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 29

Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder

Novak, G., Zai, C. C., Mirkhani, M., Shaikh, S., Vincent, J. B., Meltzer, H., Lieberman, J. A., Strauss, J., Lévesque, D., Kennedy, J. L., et al. (2010) · Genes, Brain and Behavior

Smoking Behavior and CessationSchizophrenia research and treatment

Cited by 23

COMT Val/Met and Psychopathic Traits in Children and Adolescents: A Systematic Review and New Evidence of a Developmental Trajectory toward Psychopathy

Kant, T., Koyama, E., Zai, C. C., Beitchman, J. H., & Kennedy, J. L. (2022) · International Journal of Molecular Sciences

Psychopathy, Forensic Psychiatry, Sexual OffendingNeurotransmitter Receptor Influence on Behavior

Cited by 16

FKBP5 interacts with maltreatment in children with extreme, pervasive, and persistent aggression

Bryushkova, L., Zai, C., Chen, S., Pappa, I., Mileva, V., Tiemeier, H., Bakermans-Kranenburg, M., Kennedy, J. L., & Beitchman, J. H. (2016) · Psychiatry Research

Child Abuse and TraumaChild and Adolescent Psychosocial and Emotional Development

Cited by 13

Evidence for association of vasopressin receptor 1A promoter region repeat with childhood onset aggression

Vollebregt, O., Koyama, E., Zai, C. C., Shaikh, S. A., Lisoway, A. J., Kennedy, J. L., & Beitchman, J. H. (2021) · Journal of Psychiatric Research

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 13

Possible association between the prolactin receptor gene and callous-unemotional traits among aggressive children

Hirata, Y., Zai, C. C., Nowrouzi, B., Shaikh, S. A., Kennedy, J. L., & Beitchman, J. H. (2016) · Psychiatric Genetics

Psychopathy, Forensic Psychiatry, Sexual OffendingNeurotransmitter Receptor Influence on Behavior

Cited by 5