Kennedy, James L.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, Stahl, E. A., BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., et al. (2019) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,519

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Psychiatric GWAS Consortium Bipolar Disorder Working Group, Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., et al. (2011) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,344

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Initiative, A. N. G., Watson, H. J., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., Bryois, J., Hinney, A., et al. (2019) · Nature Genetics

Eating Disorders and BehaviorsGenetic Associations and Epidemiology

Cited by 1,109

Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes

Setiawan, E., Wilson, A. A., Mizrahi, R., Rusjan, P. M., Miler, L., Rajkowska, G., Suridjan, I., Kennedy, J. L., Rekkas, P. V., Houle, S., et al. (2015) · JAMA Psychiatry

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 939

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

The Wellcome Trust Case Control Consortium, Liu, J. Z., Tozzi, F., Waterworth, D. M., Pillai, S. G., Muglia, P., Middleton, L., Berrettini, W., Knouff, C. W., Yuan, X., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologySmoking Behavior and Cessation

Cited by 614

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 544

The social and economic burden of treatment-resistant schizophrenia: a systematic literature review

Kennedy, J. L., Altar, C. A., Taylor, D. L., Degtiar, I., & Hornberger, J. C. (2014) · International Clinical Psychopharmacology

Schizophrenia research and treatmentMental Health Treatment and Access

Cited by 392

Genome-wide association study of obsessive-compulsive disorder

Stewart, S. E., Yu, D., Scharf, J. M., Neale, B. M., Fagerness, J. A., Mathews, C. A., Arnold, P. D., Evans, P. D., Gamazon, E. R., Osiecki, L., et al. (2013) · Molecular Psychiatry

Obsessive-Compulsive Spectrum DisordersGenetic Associations and Epidemiology

Cited by 384

Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder

Arnold, P. D., Sicard, T., Burroughs, E., Richter, M. A., & Kennedy, J. L. (2006) · Archives of General Psychiatry

Obsessive-Compulsive Spectrum DisordersNeurotransmitter Receptor Influence on Behavior

Cited by 357

Dopamine for “Wanting” and Opioids for “Liking”: A Comparison of Obese Adults With and Without Binge Eating

Davis, C. A., Levitan, R. D., Reid, C., Carter, J. C., Kaplan, A. S., Patte, K. A., King, N., Curtis, C., & Kennedy, J. L. (2009) · Obesity

Eating Disorders and BehaviorsNeurotransmitter Receptor Influence on Behavior

Cited by 314

Suicide risk in bipolar patients: the role of co‐morbid substance use disorders

Dalton, E. J., Cate‐Carter, T. D., Mundo, E., Parikh, S. V., & Kennedy, J. L. (2003) · Bipolar Disorders

Bipolar Disorder and TreatmentSuicide and Self-Harm Studies

Cited by 275

Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention

Swanson, J., Oosterlaan, J., Murias, M., Schuck, S., Flodman, P., Spence, M. A., Wasdell, M., Ding, Y., Chi, H.-C., Smith, M., et al. (2000) · Proceedings of the National Academy of Sciences

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 267

Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder

Davis, C., Levitan, R. D., Kaplan, A. S., Carter, J., Reid, C., Curtis, C., Patte, K., Hwang, R., & Kennedy, J. L. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Eating Disorders and BehaviorsNeurotransmitter Receptor Influence on Behavior

Cited by 200

Serotonin Transporter Polymorphisms and Persistent, Pervasive Childhood Aggression

Beitchman, J. H., Baldassarra, L., Mik, H., De Luca, V., King, N., Bender, D., Ehtesham, S., & Kennedy, J. L. (2006) · American Journal of Psychiatry

Neurotransmitter Receptor Influence on BehaviorPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 167

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J., Murnyak, B., Wendt, F., Adams, M., et al. (2023) · American Journal of Psychiatry

Genetic Associations and EpidemiologySuicide and Self-Harm Studies

Cited by 160

Translocator Protein (18 kDa) Polymorphism (rs6971) Explains in-vivo Brain Binding Affinity of the PET Radioligand [ 18 F]-FEPPA

Mizrahi, R., Rusjan, P. M., Kennedy, J., Pollock, B., Mulsant, B., Suridjan, I., De Luca, V., Wilson, A. A., & Houle, S. (2012) · Journal of Cerebral Blood Flow & Metabolism

Neuroinflammation and Neurodegeneration MechanismsMedical Imaging Techniques and Applications

Cited by 155

Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study

McGrath, L. M., Yu, D., Marshall, C., Davis, L. K., Thiruvahindrapuram, B., Li, B., Cappi, C., Gerber, G., Wolf, A., Schroeder, F. A., et al. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry

Obsessive-Compulsive Spectrum DisordersGenomic variations and chromosomal abnormalities

Cited by 141

Meta‐analysis of association between obsessive‐compulsive disorder and the 3′ region of neuronal glutamate transporter gene SLC1A1

Stewart, S. E., Mayerfeld, C., Arnold, P. D., Crane, J. R., O'Dushlaine, C., Fagerness, J. A., Yu, D., Scharf, J. M., Chan, E., Kassam, F., et al. (2013) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Obsessive-Compulsive Spectrum DisordersGenetic Associations and Epidemiology

Cited by 102

Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive-compulsive disorder

Arnold, P. D., MacMaster, F. P., Richter, M. A., Hanna, G. L., Sicard, T., Burroughs, E., Mirza, Y., Easter, P. C., Rose, M., Kennedy, J. L., et al. (2009) · Psychiatry Research: Neuroimaging

Obsessive-Compulsive Spectrum DisordersNeurotransmitter Receptor Influence on Behavior

Cited by 91

Association of the serotonin transporter and 5HT1Dβ receptor genes with extreme, persistent and pervasive aggressive behaviour in children

Davidge, K. M., Atkinson, L., Douglas, L., Lee, V., Shapiro, S., Kennedy, J. L., & Beitchman, J. H. (2004) · Psychiatric Genetics

Neurotransmitter Receptor Influence on BehaviorPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 84

The early care environment and DNA methylome variation in childhood

Garg, E., Chen, L., Nguyen, T. T. T., Pokhvisneva, I., Chen, L. M., Unternaehrer, E., MacIsaac, J. L., McEwen, L. M., Mah, S. M., Gaudreau, H., et al. (2018) · Development and Psychopathology

Epigenetics and DNA MethylationMaternal Mental Health During Pregnancy and Postpartum

Cited by 82