The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Regulation of gene expression in trypanosomatids: living with polycistronic transcription
Open accessAbstract
In trypanosomes, RNA polymerase II transcription is polycistronic and individual mRNAs are excised by trans -splicing and polyadenylation. The lack of individual gene transcription control is compensated by control of mRNA processing, translation and degradation. Although the basic mechanisms of mRNA decay and translation are evolutionarily conserved, there are also unique aspects, such as the existence of six cap-binding translation initiation factor homologues, a novel decapping enzyme and an mRNA stabilizing complex that is recruited by RNA-binding proteins. High-throughput analyses have identified nearly a hundred regulatory mRNA-binding proteins, making trypanosomes valuable as a model system to investigate post-transcriptional regulation.
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The Revised Classification of Eukaryotes
Adl, S. M., Simpson, A. G. B., Lane, C. E., Lukeš, J., Bass, D., Bowser, S. S., Brown, M. W., Burki, F., Dunthorn, M., Hampl, V., et al. (2012) · Journal of Eukaryotic Microbiology · doi:10.1111/j.1550-7408.2012.00644.x · Cited by 1,680
Translational control by 5′-untranslated regions of eukaryotic mRNAs
Hinnebusch, A. G., Ivanov, I. P., & Sonenberg, N. (2016) · Science · doi:10.1126/science.aad9868 · Cited by 1,079
Codon optimality, bias and usage in translation and mRNA decay
Hanson, G., & Coller, J. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.91 · Cited by 825
Kalyna, M., Simpson, C. G., Syed, N. H., Lewandowska, D., Marquez, Y., Kusenda, B., Marshall, J., Fuller, J., Cardle, L., McNicol, J., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gkr932 · Cited by 480
Structural and molecular mechanisms for the control of eukaryotic 5′–3′ mRNA decay
Mugridge, J. S., Coller, J., & Gross, J. D. (2018) · Nature Structural & Molecular Biology · doi:10.1038/s41594-018-0164-z · Cited by 133
Wasmuth, E. V., & Lima, C. D. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.07.012 · Cited by 114
Cited by
The SPARC complex defines RNAPII promoters in Trypanosoma brucei
Staneva, D. P., Bresson, S., Auchynnikava, T., Spanos, C., Rappsilber, J., Jeyaprakash, A. A., Tollervey, D., Matthews, K. R., & Allshire, R. C. (2022) · eLife · doi:10.7554/elife.83135 · Cited by 13
The Elusive Trypanosoma cruzi Disperse Gene Protein Family (DGF-1)
Ramírez, J. L. (2023) · Pathogens · doi:10.3390/pathogens12020292 · Cited by 9
Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody
Pinto Torres, J. E., Claes, M., Hendrickx, R., Yuan, M., Smiejkowska, N., Van Wielendaele, P., Hacisuleyman, A., De Winter, H., Muyldermans, S., Michels, P. A., et al. (2025) · eLife · doi:10.7554/elife.100066 · Cited by 2
Metadata
- Authors
- Clayton, C.
- Venue
- Open Biology
- Publisher
- The Royal Society
- Published
- 2019-06
- Volume
- 9
- Issue
- 6
- Pages
- 190072-190072
- ISSN
- 2046-2441 (ISSN-L)
- OpenAlex
- W2948560706
- Cited by
- 282
- References
- 6
- FWCI
- 19.71
- Type
- journal article
- Language
- en
- Open access
- gold
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