Evolutionary Forces Shaping the Golgi Glycosylation Machinery: Why Cell Surface Glycans Are Universal to Living Cells

Pattern Recognition Receptors and Inflammation

Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895 · see citing works

Biological roles of oligosaccharides: all of the theories are correct

Varki, A. P. (1993) · Glycobiology · doi:10.1093/glycob/3.2.97 · Cited by 5,203 · see citing works

Central Dogma of Molecular Biology

CRICK, F. (1970) · Nature · doi:10.1038/227561a0 · Cited by 3,444 · see citing works

The acute phase response

Baumann, H., & Gauldie, J. (1994) · Immunology Today · doi:10.1016/0167-5699(94)90137-6 · Cited by 2,907 · see citing works

Biological roles of glycans

Varki, A. (2017) · Glycobiology · doi:10.1093/glycob/cww086 · Cited by 2,635 · see citing works

Long noncoding RNAs: functional surprises from the RNA worldPreprint

Wilusz, J. E., Sunwoo, H., & Spector, D. L. (2009) · Genes & Development · doi:10.1101/gad.1800909 · Cited by 2,298 · see citing works

Proteomics by Mass Spectrometry: Approaches, Advances, and Applications

Yates, J. R., Ruse, C. I., & Nakorchevsky, A. (2009) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-061008-124934 · Cited by 1,078 · see citing works

Lipidomics: coming to grips with lipid diversity

Shevchenko, A., & Simons, K. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2934 · Cited by 828 · see citing works

Visualization of omics data for systems biology

Gehlenborg, N., O’Donoghue, S. I., Baliga, N. S., Goesmann, A., Hibbs, M., Kitano, H., Kohlbacher, O., Neuweger, H., Schneider, R., Tenenbaum, D., et al. (2010) · Nature Methods · doi:10.1038/nmeth.1436 · Cited by 622 · see citing works

The Endothelial Glycocalyx Protects Against Myocardial Edema

van den Berg, B. M., Vink, H., & Spaan, J. A. E. (2003) · Circulation Research · doi:10.1161/01.res.0000065917.53950.75 · Cited by 536 · see citing works

Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain–Barré syndrome

Yuki, N., Susuki, K., Koga, M., Nishimoto, Y., Odaka, M., Hirata, K., Taguchi, K., Miyatake, T., Furukawa, K., Kobata, T., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402391101 · Cited by 497 · see citing works

Evolutionary considerations in relating oligosaccharide diversity to biological function

Gagneux, P., & Varki, A. (1999) · Glycobiology · doi:10.1093/glycob/9.8.747 · Cited by 495 · see citing works

Golgi GlycosylationPreprint

Stanley, P. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005199 · Cited by 462 · see citing works

Proteoglycans and Sulfated GlycosaminoglycansPreprint

Esko, J. D., Kimata, K., & Lindahl, U. (2009) · Europe PMC (PubMed Central) · doi:10.1101/glycobiology.3e.017 · Cited by 455 · see citing works

Metabolism, Cell Surface Organization, and Disease

Dennis, J. W., Nabi, I. R., & Demetriou, M. (2009) · Cell · doi:10.1016/j.cell.2009.12.008 · Cited by 450 · see citing works

Plant‐specific glycosylation patterns in the context of therapeutic protein production

Gomord, V., Fitchette, A., Menu‐Bouaouiche, L., Saint‐Jore‐Dupas, C., Plasson, C., Michaud, D., & Faye, L. J.-Y. (2010) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2009.00497.x · Cited by 419 · see citing works

The α‐gal epitope and the anti‐Gal antibody in xenotransplantation and in cancer immunotherapy

Galili, U. (2005) · Immunology and Cell Biology · doi:10.1111/j.1440-1711.2005.01366.x · Cited by 335 · see citing works

Human Symbionts Use a Host-Like Pathway for Surface Fucosylation

Coyne, M. J., Reinap, B., Lee, M. M., & Comstock, L. E. (2005) · Science · doi:10.1126/science.1106469 · Cited by 304 · see citing works

The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach

Harduin‐Lepers, A., Mollicone, R., Delannoy, P., & Oriol, R. (2005) · Glycobiology · doi:10.1093/glycob/cwi063 · Cited by 302 · see citing works

Uniquely human evolution of sialic acid genetics and biology

Varki, A. P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914634107 · Cited by 278 · see citing works

Glycomics and disease markers

An, H. J., Kronewitter, S. R., Leoz, M. L. A. D., & Lebrilla, C. B. (2009) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2009.08.015 · Cited by 268 · see citing works

Nothing in Glycobiology Makes Sense, except in the Light of Evolution

Varki, A. P. (2006) · Cell · doi:10.1016/j.cell.2006.08.022 · Cited by 250 · see citing works

Models for Golgi Traffic: A Critical AssessmentPreprint

Glick, B. S., & Luini, A. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005215 · Cited by 234 · see citing works

Exploring Disease through Metabolomics

Vinayavekhin, N., Homan, E. A., & Saghatelian, A. (2009) · ACS Chemical Biology · doi:10.1021/cb900271r · Cited by 232 · see citing works

The Sialome—Far More Than the Sum of Its Parts

Cohen, M., & Varki, A. P. (2010) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2009.0148 · Cited by 232 · see citing works

Mass spectrometry in the analysis of N-linked and O-linked glycans

North, S. J., Hitchen, P. G., Haslam, S. M., & Dell, A. (2009) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2009.05.005 · Cited by 221 · see citing works

Definition of a bacterial virulence factor: sialylation of the group B streptococcal capsule.

Wessels, M. R., Rubens, C. E., Benedi, V. J., & Kasper, D. L. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.22.8983 · Cited by 216 · see citing works

Nuclear magnetic resonance of hydroxyl and amido, protons of oligosaccharides in aqueous solution: evidence for a strong intramolecular hydrogen bond in sialic acid residues

Poppe, L., & van HALBEEK, H. (1991) · Journal of the American Chemical Society · doi:10.1021/ja00001a055 · Cited by 200 · see citing works

Regulation of Mucin Genes in Chronic Inflammatory Airway Diseases

Voynow, J. A., Gendler, S. J., & Rose, M. C. (2006) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2006-0035sf · Cited by 196 · see citing works

Molecular simulations of carbohydrates and protein–carbohydrate interactions: motivation, issues and prospects

Fadda, E., & Woods, R. J. (2010) · Drug Discovery Today · doi:10.1016/j.drudis.2010.06.001 · Cited by 188 · see citing works

Journeys through the Golgi—taking stock in a new era

Emr, S. D., Glick, B. S., Linstedt, A. D., Lippincott‐Schwartz, J., Luini, A., Malhotra, V., Marsh, B. J., Nakano, A., Pfeffer, S. R., Rabouille, C., et al. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200909011 · Cited by 183 · see citing works

Evolving views of protein glycosylation

Drickamer, K. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01246-8 · Cited by 180 · see citing works

O-GalNAc GlycansPreprint

Brockhausen, I., & Stanley, P. (2009) · Europe PMC (PubMed Central) · doi:10.1101/glycobiology.3e.010 · Cited by 177 · see citing works

Mechanisms of Protein Retention in the GolgiPreprint

Banfield, D. K. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005264 · Cited by 159 · see citing works

Elevated Golgi pH impairs terminal N‐glycosylation by inducing mislocalization of Golgi glycosyltransferases

Rivinoja, A., Hassinen, A., Kokkonen, N., Kauppila, A., & Kellokumpu, S. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21744 · Cited by 151 · see citing works

Macrophage lectins in host defence

Linehan, S. A., Martínez‐Pomares, L., & Gordon, S. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)00300-2 · Cited by 150 · see citing works

Glycomic Analysis of Sialic Acid Linkages in Glycans Derived from Blood Serum Glycoproteins

Alley, W. R., & Novotný, M. V. (2010) · Journal of Proteome Research · doi:10.1021/pr901210r · Cited by 150 · see citing works

Adhesins as Lectins: Specificity and Role in Infection

Ofek, I., & Sharon, N. (1990) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-74703-8_5 · Cited by 147 · see citing works

Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure

Lewis, A. L., Desa, N., Hansen, E. E., Knirel, Y. A., Gordon, J. I., Gagneux, P., Nizet, V., & Varki, A. P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902431106 · Cited by 138 · see citing works

Localization of Golgi-resident glycosyltransferases

Tu, L., & Banfield, D. K. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0126-z · Cited by 133 · see citing works

Bioenergetics, the origins of complexity, and the ascent of man

Wallace, D. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914635107 · Cited by 129 · see citing works

Evolution of carbohydrate antigens—microbial forces shaping host glycomes?

Bishop, J. R., & Gagneux, P. (2007) · Glycobiology · doi:10.1093/glycob/cwm005 · Cited by 126 · see citing works

The Acquired Immune System

Hedrick, S. M. (2004) · Immunity · doi:10.1016/j.immuni.2004.08.020 · Cited by 122 · see citing works

Historical Background and OverviewPreprint

Varki, A. P., & Sharon, N. (2009) · Europe PMC (PubMed Central) · doi:10.1101/glycobiology.3e.001 · Cited by 105 · see citing works

Nucleotide Sugar Transporters of the Golgi Apparatus: From Basic Science to Diseases

Caffaro, C. E., & Hirschberg, C. B. (2006) · Accounts of Chemical Research · doi:10.1021/ar0400239 · Cited by 102 · see citing works

Structures Common to Different GlycansPreprint

Stanley, P., & Cummings, R. D. (2009) · Europe PMC (PubMed Central) · doi:10.1101/glycobiology.3e.014 · Cited by 95 · see citing works

ABO blood group and related antigens, natural antibodies and transplantation

Milland, J., & Sandrin, M. S. (2006) · Tissue Antigens · doi:10.1111/j.1399-0039.2006.00721.x · Cited by 89 · see citing works

The Mimicry of Human Glycolipids and Glycosphingolipids by the Lipooligosaccharides of Pathogenic and

Harvey, H. A., Swords, W. E., & Apicella, M. A. (2001) · Journal of Autoimmunity · doi:10.1006/jaut.2000.0477 · Cited by 88 · see citing works

Cellular Organization of GlycosylationPreprint

Varki, A. P., Esko, J. D., & Colley, K. (2009) · doi:10.1101/glycobiology.3e.004 · Cited by 86 · see citing works

Two modes of evolution

Valen, L. V. (1974) · Nature · doi:10.1038/252298a0 · Cited by 86 · see citing works

Computational glycoscience: characterizing the spatial and temporal properties of glycans and glycan–protein complexes

Woods, R. J., & Tessier, M. B. (2010) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2010.07.005 · Cited by 81 · see citing works

Golgi Glycosylation and Human Inherited DiseasesPreprint

Freeze, H. H., & Ng, B. G. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005371 · Cited by 81 · see citing works

N ‐glycans of recombinant human interferon‐γ change during batch culture of chinese hamster ovary cells

Hooker, A. D., Goldman, M. H., Markham, N. H., James, D. C., Ison, A. P., Bull, A. T., Strange, P. G., Salmon, I., Baines, A. J., & Jenkins, N. (1995) · Biotechnology and Bioengineering · doi:10.1002/bit.260480612 · Cited by 80 · see citing works

ABO blood group glycans modulate sialic acid recognition on erythrocytes

Cohen, M., Hurtado-Ziola, N., & Varki, A. (2009) · Blood · doi:10.1182/blood-2009-06-227041 · Cited by 75 · see citing works

Sorting out glycosylation enzymes in the Golgi apparatus

Nilsson, T., Au, C. E., & Bergeron, J. J. M. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.10.064 · Cited by 73 · see citing works

Evolution and Diversity of the GolgiPreprint

Klute, M. J., Melançon, P., & Dacks, J. B. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a007849 · Cited by 67 · see citing works

Evolution of Glycan DiversityPreprint

Varki, A. P., Freeze, H. H., & Gagneux, P. (2009) · Europe PMC (PubMed Central) · doi:10.1101/glycobiology.3e.020 · Cited by 62 · see citing works

Microbial Lectins: Hemagglutinins, Adhesins, and Toxins

Esko, J. D., & Sharon, N. (2009) · Cited by 61 · see citing works

Inhibition of Golgi Apparatus Glycosylation Causes Endoplasmic Reticulum Stress and Decreased Protein Synthesis

Xu, Y., Liu, L., Caffaro, C. E., & Hirschberg, C. B. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.134544 · Cited by 52 · see citing works

Molecular Mimicry of Host Structures by Lipooligosaccharides of Neisseria Meningitidis: Characterization of Sialylated and Nonsialylated Lacto-N-Neotetraose (Galß1-4GlcNAcß1-3Galβ1-4Glc) Structures in Lipooligosaccharides Using Monoclonal Antibodies and Specific Lectins

Tsai, C.-M. (2001) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-1267-7_35 · Cited by 37 · see citing works

Bacterium–Host Protein–Carbohydrate Interactions

Ilver, D., Johansson, P., Miller‐Podraza, H., Nyholm, P., Teneberg, S., & Karlsson, K. (2003) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(03)01049-8 · Cited by 35 · see citing works

Footprints of nonsentient design inside the human genome

Avise, J. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914609107 · Cited by 24 · see citing works

A Genomic View of GlycobiologyPreprint

Henrissat, B., Surolia, A., & Stanley, P. (2009) · Europe PMC (PubMed Central) · doi:10.1101/glycobiology.3e.008 · Cited by 24 · see citing works

Sialic Acids -- Essentials of Glycobiology

Varki, A. P., Rd, C., Jd, E., Freeze, H. H., Stanley, P., Bertozzi, C. R., Hart, G. W., & Me, E. (2009) · Cited by 23 · see citing works

Other Classes of ER/Golgi-derived Glycans

Freeze, H. H., & Haltiwanger, R. S. (2009) · Europe PMC (PubMed Central) · Cited by 20 · see citing works

Glycosylphosphatidylinositol Anchors -- Essentials of Glycobiology

Varki, A. P., Rd, C., Jd, E., Freeze, H. H., Stanley, P., Bertozzi, C. R., Hart, G. W., & Me, E. (2009) · Cited by 11 · see citing works

Glycosylphosphatidylinositol Anchors

Thomson, L. M., Fontaine, T., Mehlert, A., & Ferguson, M. A. J. (2003) · NATO science series. Series II, Mathematics, physics and chemistry · doi:10.1007/978-94-007-0958-4_18 · Cited by 6 · see citing works

Hyaluronan -- Essentials of Glycobiology

Varki, A. P., Rd, C., Jd, E., Freeze, H. H., Stanley, P., Bertozzi, C. R., Hart, G. W., & Me, E. (2009) · Cited by 2 · see citing works

Deuterostomes -- Essentials of Glycobiology

Varki, A. P., Rd, C., Jd, E., Freeze, H. H., Stanley, P., Bertozzi, C. R., Hart, G. W., & Me, E. (2009) · Cited by 2 · see citing works

Viridiplantae -- Essentials of Glycobiology

Varki, A. P., Rd, C., Jd, E., Freeze, H. H., Stanley, P., Bertozzi, C. R., Hart, G. W., & Me, E. (2009) · Cited by 1 · see citing works

Biological roles of glycans

Varki, A. (2017) · Glycobiology · doi:10.1093/glycob/cww086 · Cited by 2,635 · see citing works

Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration

Schnaar, R. L., Gerardy-Schahn, R., & Hildebrandt, H. (2014) · Physiological Reviews · doi:10.1152/physrev.00033.2013 · Cited by 745 · see citing works

Breast milk oligosaccharides: structure-function relationships in the neonate

Smilowitz, J. T., Lebrilla, C. B., Mills, D. A., German, J. B., & Freeman, S. L. (2014) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071813-105721 · Cited by 410 · see citing works

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Stewart-Jones, G. B. E., Soto, C. S., Lemmin, T., Chuang, G., Druz, A., Kong, R., Thomas, P. V., Wagh, K., Zhou, T., Behrens, A., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.010 · Cited by 406 · see citing works

Modulation of Immune Tolerance via Siglec-Sialic Acid Interactions

Lübbers, J., Rodríguez, E., & van Kooyk, Y. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02807 · Cited by 261 · see citing works

A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry–Based Glycoproteomics

Riley, N. M., Bertozzi, C. R., & Pitteri, S. J. (2020) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r120.002277 · Cited by 234 · see citing works

Gangliosides of the Vertebrate Nervous System

Schnaar, R. L. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.05.020 · Cited by 198 · see citing works

Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms

Gügi, B., Costaouëc, T. L., Burel, C., Lerouge, P., Helbert, W., & Bardor, M. (2015) · Marine Drugs · doi:10.3390/md13095993 · Cited by 191 · see citing works

Effective Use of Mass Spectrometry for Glycan and Glycopeptide Structural Analysis

Leymarie, N., & Zaia, J. (2012) · Analytical Chemistry · doi:10.1021/ac3000573 · Cited by 185 · see citing works

Cell wall O-glycoproteins and N-glycoproteins: aspects of biosynthesis and function

Nguema‐Ona, E., Vicré‐Gibouin, M., Gotté, M., Plancot, B., Lerouge, P., Bardor, M., & Driouich, A. (2014) · Frontiers in Plant Science · doi:10.3389/fpls.2014.00499 · Cited by 177 · see citing works

Ganglioside Biochemistry

Kolter, T. (2012) · ISRN Biochemistry · doi:10.5402/2012/506160 · Cited by 167 · see citing works

Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins

Bornhöfft, K. F., Goldammer, T., Rebl, A., & Galuska, S. P. (2018) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2018.05.008 · Cited by 150 · see citing works

Mapping the O‐glycoproteome using site‐specific extraction of O‐linked glycopeptides (EXoO)

Yang, W., Ao, M., Hu, Y., Li, Q. K., & Zhang, H. (2018) · Molecular Systems Biology · doi:10.15252/msb.20188486 · Cited by 151 · see citing works

Glycobiology simplified: diverse roles of glycan recognition in inflammation

Schnaar, R. L. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.3ri0116-021r · Cited by 141 · see citing works

Glycan variation and evolution in the eukaryotes

Corfield, A. P., & Berry, M. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.04.004 · Cited by 134 · see citing works

Alternative glycosylation modulates function of IgG and other proteins — Implications on evolution and disease

Gornik, O., Štambuk, T., & Lauc, G. (2011) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.12.004 · Cited by 131 · see citing works

ABO Blood Groups and Cardiovascular Diseases

Zhang, H., Mooney, C. J., & Reilly, M. P. (2012) · International Journal of Vascular Medicine · doi:10.1155/2012/641917 · Cited by 122 · see citing works

Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012

Leymarie, N., Griffin, P. J., Jonscher, K. R., Kolarich, D., Orlando, R., McComb, M. E., Zaia, J., Aguilan, J. T., Alley, W. R., Altmann, F., et al. (2013) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m113.030643 · Cited by 112 · see citing works

Exploring the N-glycosylation Pathway in Chlamydomonas reinhardtii Unravels Novel Complex Structures

Mathieu‐Rivet, E., Scholz, M., Arias, C., Dardelle, F., Schulze, S., Mauff, F. L., Teo, G., Hochmal, A. K., Blanco-Rivero, A., Loutelier‐Bourhis, C., et al. (2013) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m113.028191 · Cited by 109 · see citing works

Glycans and glycan-binding proteins in immune regulation: A concise introduction to glycobiology for the allergist

Schnaar, R. L. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.10.057 · Cited by 105 · see citing works

Sialylation regulates brain structure and function

Yoo, S., Motari, M. G., Susuki, K., Prendergast, J., Mountney, A., Hurtado, A., & Schnaar, R. L. (2015) · The FASEB Journal · doi:10.1096/fj.15-270983 · Cited by 101 · see citing works

Hypotheses on the evolution of hyaluronan: A highly ironic acid

Csoka, A. B., & Stern, R. (2013) · Glycobiology · doi:10.1093/glycob/cws218 · Cited by 97 · see citing works

B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan

Praissman, J. L., Live, D. H., Wang, S., Ramiah, A., Chinoy, Z. S., Boons, G., Moremen, K. W., & Wells, L. (2014) · eLife · doi:10.7554/elife.03943 · Cited by 97 · see citing works

Protein N-glycosylation in eukaryotic microalgae and its impact on the production of nuclear expressed biopharmaceuticals

Mathieu‐Rivet, E., Kiefer‐Meyer, M., Vanier, G., Ovide, C., Burel, C., Lerouge, P., & Bardor, M. (2014) · Frontiers in Plant Science · doi:10.3389/fpls.2014.00359 · Cited by 96 · see citing works

CH−π Interactions in Glycan Recognition

Kiessling, L. L., & Diehl, R. C. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.1c00413 · Cited by 90 · see citing works

Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood

Deng, L., Bensing, B. A., Thamadilok, S., Yu, H., Lau, K., Chen, X., Ruhl, S., Sullam, P. M., & Varki, A. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004540 · Cited by 88 · see citing works

Glycosaminoglycan Glycomics Using Mass Spectrometry

Zaia, J. (2013) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r112.026294 · Cited by 88 · see citing works

Modulation of Glycan Recognition by Clustered Saccharide Patches

(2014) · International Review of Cell and Molecular Biology · doi:10.1016/b978-0-12-800097-7.00003-8 · Cited by 84 · see citing works

A Targeted Glycan-Related Gene Screen Reveals Heparan Sulfate Proteoglycan Sulfation Regulates WNT and BMP Trans-Synaptic Signaling

Dani, N., Nahm, M., Lee, S., & Broadie, K. S. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1003031 · Cited by 81 · see citing works

Biochemical, Cellular, Physiological, and Pathological Consequences of Human Loss of N‐Glycolylneuraminic Acid

Okerblom, J., & Varki, A. P. (2017) · ChemBioChem · doi:10.1002/cbic.201700077 · Cited by 80 · see citing works

Genome-Scale Modeling of the Protein Secretory Machinery in Yeast

Feizi, A., Österlund, T., Petranović, D., Bordel, S., & Nielsen, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063284 · Cited by 79 · see citing works

Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode

Agrawal, P., Kurcon, T., Pilobello, K. T., Rakus, J. F., Koppolu, S., Liu, Z., Batista, B. S., Eng, W. S., Hsu, K.-L., Liang, Y., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321524111 · Cited by 77 · see citing works

Glycan Evolution in Response to Collaboration, Conflict, and Constraint

Springer, S. A., & Gagneux, P. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.r112.424523 · Cited by 76 · see citing works

Salmonella Degrades the Host Glycocalyx Leading to Altered Infection and Glycan Remodeling

Arabyan, N., Park, D., Foutouhi, S. H., Weis, A. M., Huang, B. C., Williams, C. C., Desai, P., Shah, J., Jeannotte, R., Kong, N. T., et al. (2016) · Scientific Reports · doi:10.1038/srep29525 · Cited by 76 · see citing works

Cell walls: a comparative view of the composition of cell surfaces of plants, algae, and microorganisms

Fuertes-Rabanal, M., Rebaque, D., Largo‐Gosens, A., Encina, A., & Mélida, H. (2024) · Journal of Experimental Botany · doi:10.1093/jxb/erae512 · Cited by 67 · see citing works

Multiple N-Glycans Cooperate in the Subcellular Targeting and Functioning of Arabidopsis KORRIGAN1

Rips, S., Bentley, N. L., Jeong, I. S., Welch, J. L., von Schaewen, A., & Koiwa, H. (2014) · The Plant Cell · doi:10.1105/tpc.114.129718 · Cited by 61 · see citing works

Glycans – the third revolution in evolution

Lauc, G., Krištić, J., & ZoldoÅ¡, V. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00145 · Cited by 60 · see citing works

Notable Aspects of Glycan-Protein Interactions

Cohen, M. (2015) · Biomolecules · doi:10.3390/biom5032056 · Cited by 57 · see citing works

Recessive GM3 synthase deficiency: Natural history, biochemistry, and therapeutic frontier

Bowser, L. E., Young, M., Wenger, O. K., Ammous, Z., Brigatti, K. W., Carson, V. J., Moser, T., Deline, J., Aoki, K., Morlet, T. G., et al. (2019) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2019.01.013 · Cited by 56 · see citing works

Exploration of Sialic Acid Diversity and Biology Using Sialoglycan Microarrays

Deng, L., Chen, X., & Varki, A. P. (2013) · Biopolymers · doi:10.1002/bip.22314 · Cited by 55 · see citing works

Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes

Wu, Z., Liu, Y., Ma, C., Li, L., Bai, J., Byrd-Leotis, L. A., Lasanajak, Y., Guo, Y., Wen, L., Zhu, H., et al. (2016) · Organic & Biomolecular Chemistry · doi:10.1039/c6ob01982j · Cited by 50 · see citing works

Healthy human serum N-glycan profiling reveals the influence of ethnic variation on the identified cancer-relevant glycan biomarkers

Gebrehiwot, A. G., Seifu, D., Kassaye, Y. M., Rehan, I. F., Rangappa, S., Hinou, H., Kamiyama, T., & Nishimura, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0209515 · Cited by 50 · see citing works

Towards a new avenue for producing therapeutic proteins: Microalgae as a tempting green biofactory

Dehghani, J., Adibkia, K., Movafeghi, A., Maleki, H., Saeedi, N., & Omidi, Y. (2019) · Biotechnology Advances · doi:10.1016/j.biotechadv.2019.107499 · Cited by 51 · see citing works

Development of plant-made monoclonal antibodies against viral infections

Chen, Q. (2021) · Current Opinion in Virology · doi:10.1016/j.coviro.2021.12.005 · Cited by 49 · see citing works

Human N -acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite

Kadirvelraj, R., Yang, J., Sanders, J. H., Liu, L., Ramiah, A., Prabhakar, P. K., Boons, G., Wood, Z. A., & Moremen, K. W. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1716988115 · Cited by 47 · see citing works

Evolution of sialic acids: Implications in xenotransplant biology

Paul, A., & Padler‐Karavani, V. (2018) · Xenotransplantation · doi:10.1111/xen.12424 · Cited by 45 · see citing works

Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies

Tytgat, H. L. P., Lin, C., Levasseur, M. D., Tomek, M. B., Rutschmann, C., Mock, J., Liebscher, N., Terasaka, N., Azuma, Y., Wetter, M., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13283-2 · Cited by 45 · see citing works

Hitting the Sweet Spot: Glycans as Targets of Fungal Defense Effector Proteins

Künzler, M. (2015) · Molecules · doi:10.3390/molecules20058144 · Cited by 43 · see citing works

Are humans prone to autoimmunity? Implications from evolutionary changes in hominin sialic acid biology

Varki, A. P. (2017) · Journal of Autoimmunity · doi:10.1016/j.jaut.2017.07.011 · Cited by 43 · see citing works

Translation of genome to glycome: role of the Golgi apparatus

Pothukuchi, P., Agliarulo, I., Russo, D., Rizzo, R., Russo, F., & Parashuraman, S. (2019) · FEBS Letters · doi:10.1002/1873-3468.13541 · Cited by 43 · see citing works

Integrative View of α2,3-Sialyltransferases (ST3Gal) Molecular and Functional Evolution in Deuterostomes: Significance of Lineage-Specific Losses

Petit, D. P., Teppa, E., Mir, A., Vicogne, D., Thisse, C., Thisse, B., Filloux, C., & Harduin‐Lepers, A. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu395 · Cited by 42 · see citing works

Mammalian protein glycosylation – structure versus function

Defaus, S., Gupta, P., Andreu, D., & Gallego, R. G. (2014) · The Analyst · doi:10.1039/c3an02245e · Cited by 40 · see citing works

Investigating virus–glycan interactions using glycan microarrays

Smith, D. F., & Cummings, R. D. (2014) · Current Opinion in Virology · doi:10.1016/j.coviro.2014.05.005 · Cited by 41 · see citing works

Ubiquitous Importance of Protein Glycosylation

Krištić, J., & Lauc, G. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6493-2_1 · Cited by 40 · see citing works

Abnormal Sphingolipid World in Inflammation Specific for Lysosomal Storage Diseases and Skin Disorders

Moskot, M., Bocheńska, K., Jakóbkiewicz‐Banecka, J., Banecki, B., & Gabig‐Cimińska, M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19010247 · Cited by 39 · see citing works

Expanding Proteostasis by Membrane Trafficking NetworksPreprint

Hutt, D. M., & Balch, W. E. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a013383 · Cited by 40 · see citing works

Comparisons of N-glycans across invertebrate phyla

Paschinger, K., & Wilson, I. (2019) · Parasitology · doi:10.1017/s0031182019000398 · Cited by 35 · see citing works

Computational Biology and Chemistry

Behzadi, P., & Bernabò, N. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.83539 · Cited by 39 · see citing works

Exploring glycans as vital biological macromolecules: A comprehensive review of advancements in biomedical frontiers

Arora, K., Sherilraj, P. M., Abutwaibe, K. A., Dhruw, B., & Mudavath, S. L. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.131511 · Cited by 37 · see citing works

Tandem mass spectra of glycan substructures enable the multistage mass spectrometric identification of determinants on oligosaccharides

Everest‐Dass, A., Kolarich, D., Campbell, M. P., & Packer, N. H. (2013) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.6527 · Cited by 37 · see citing works

Glycoengineering of plants yields glycoproteins with polysialylation and other defined N-glycoforms

Chen, Q. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1610803113 · Cited by 37 · see citing works

The life cycle and enigmatic egress of coronaviruses

Prydz, K., & Saraste, J. (2022) · Molecular Microbiology · doi:10.1111/mmi.14907 · Cited by 35 · see citing works

Glycomics: Building Upon Proteomics to Advance Glycosciences

Wells, L., & Hart, G. W. (2013) · Molecular & Cellular Proteomics · doi:10.1074/mcp.e113.027904 · Cited by 33 · see citing works

Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/ miR-1-3p axis in bladder cancer

Tan, Z., Jiang, Y., Liang, L., Wu, J., Cao, L. L., Zhou, X., Song, Z., Ye, Z., Zhao, Z., Feng, H., et al. (2022) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-022-02438-7 · Cited by 32 · see citing works

Microfluidic Chip-LC/MS-based Glycomic Analysis Revealed Distinct N-glycan Profile of Rat Serum

Gao, W., Yau, L., Liu, L., Zeng, X., Chen, D., Jiang, M., Liu, J., Wang, J., & Jiang, Z. (2015) · Scientific Reports · doi:10.1038/srep12844 · Cited by 32 · see citing works

Study of structure‐dependent chromatographic behavior of glycopeptides using reversed phase nanoLC

Kozlík, P., Goldman, R., & Šanda, M. (2017) · Electrophoresis · doi:10.1002/elps.201600547 · Cited by 32 · see citing works

Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera

Alisson‐Silva, F., Liu, J. Z., Diaz, S. L., Deng, L., Gareau, M. G., Marchelletta, R. R., Chen, X., Nizet, V., Varki, N. M., Barrett, K. E., et al. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1007133 · Cited by 31 · see citing works

A general approach to explore prokaryotic protein glycosylation reveals the unique surface layer modulation of an anammox bacterium

Pabst, M., Grouzdev, D. S., Lawson, C. E., Kleikamp, H. B. C., de Ram, C., Louwen, R., Lin, Y. M., Lücker, S., van Loosdrecht, M. C. M., & Laureni, M. (2021) · The ISME Journal · doi:10.1038/s41396-021-01073-y · Cited by 32 · see citing works

Interaction of Bordetella adenylate cyclase toxin with complement receptor 3 involves multivalent glycan binding

Hasan, S., Osic̆ková, A., Bumba, L., Novák, P., Šebo, P., & Osička, R. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.12.023 · Cited by 32 · see citing works

Recent advances in expression and purification strategies for plant made vaccines

Venkataraman, S., Khan, I. H., Habibi, P., Le, M., Lippert, R., & Hefferon, K. L. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1273958 · Cited by 31 · see citing works

Posttranslational Modifications in PD-L1 Turnover and Function: From Cradle to Grave

Yu, X., Li, W., Young, K. H., & Li, Y. (2021) · Biomedicines · doi:10.3390/biomedicines9111702 · Cited by 31 · see citing works

Changes in Plasma Membrane Surface Potential of PC12 Cells as Measured by Kelvin Probe Force Microscopy

Tsai, C.-C., Hung, H., Liu, C.-P., Chen, Y., & Pan, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033849 · Cited by 31 · see citing works

The role of glycosylation in clinical allergy and immunology

Hale, R. C., Morais, D., Chou, J. S., & Stowell, S. R. (2023) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2023.09.003 · Cited by 31 · see citing works

Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis

Colomb, F., Giron, L. B., Trbojević‐Akmačić, I., Lauc, G., & Abdel‐Mohsen, M. (2019) · Current HIV/AIDS Reports · doi:10.1007/s11904-019-00433-w · Cited by 28 · see citing works

Female-induced remote regulation of sperm physiology may provide opportunities for gamete-level mate choice

Kekäläinen, J., & Evans, J. P. (2016) · Evolution · doi:10.1111/evo.13141 · Cited by 29 · see citing works

Glycan-Dependent Corneocyte Adherence of Staphylococcus epidermidis Mediated by the Lectin Subdomain of Aap

Roy, P., Horswill, A. R., & Fey, P. D. (2021) · mBio · doi:10.1128/mbio.02908-20 · Cited by 28 · see citing works

Many Light Touches Convey the Message

Dennis, J. W. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.08.010 · Cited by 27 · see citing works

Interactions of human galectins with Trypanosoma cruzi: Binding profile correlate with genetic clustering of lineages

Pineda, M. A., Corvo, L., Soto, M., Fresno, M., & Bonay, P. (2014) · Glycobiology · doi:10.1093/glycob/cwu103 · Cited by 27 · see citing works

Multiple horizontal gene transfer events have shaped plant glycosyl hydrolase diversity and function

Kfoury, B., Rodrigues, W. F. C., Kim, S., Brandizzí, F., & Del‐Bem, L. (2024) · New Phytologist · doi:10.1111/nph.19595 · Cited by 27 · see citing works

Mollusc N-glycosylation: Structures, Functions and Perspectives

Staudacher, E. (2021) · Biomolecules · doi:10.3390/biom11121820 · Cited by 25 · see citing works

Evolutionary–developmental perspectives on immune system interactions among the pregnant woman, placenta, and fetus, and responses to sexually transmitted infectious agents

Nahmias, A. J., Schollin, J., & Abramowsky, C. R. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06137.x · Cited by 25 · see citing works

The Role of Typhoid Toxin in Salmonella Typhi Virulence .

Chong, A. M., Lee, S., Yang, Y.-A., & Song, J. (2017) · Europe PMC (PubMed Central) · Cited by 25 · see citing works

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

Guo, S., Vance, T. D. R., Zahiri, H., Eves, R. L., Stevens, C. A., Hehemann, J., Vidal‐Melgosa, S., & Davies, P. L. (2021) · mBio · doi:10.1128/mbio.00130-21 · Cited by 24 · see citing works

Inflammatory Stress Causes N-Glycan Processing Deficiency in Ocular Autoimmune Disease

Woodward, A. M., Lehoux, S. D., Mantelli, F., Zazzo, A. D., Brockhausen, I., Bonini, S., & Argüeso, P. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.10.012 · Cited by 24 · see citing works

Therapeutic potential to target sialylation and SIGLECs in neurodegenerative and psychiatric diseases

Wißfeld, J., Assale, T. A., Cuevas-Ríos, G., Liao, H., & Neumann, H. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1330874 · Cited by 23 · see citing works

Targeting Tn-Antigen-Positive Human Tumors with a Recombinant Human Macrophage Galactose C-Type Lectin

Bulteau, F., Thépaut, M., Henry, M., Hurbin, A., Vanwonterghem, L., Vivès, C., Roy, A. L., Ebel, C., Renaudet, O., Fieschi, F., et al. (2021) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.1c00744 · Cited by 21 · see citing works

The Secretome and N-Glycosylation Profiles of the Charophycean Green Alga, Penium margaritaceum, Resemble Those of Embryophytes

Ruíz-May, E., Sørensen, I., Fei, Z., Zhang, S., Domozych, D. S., & Rose, J. K. C. (2018) · Proteomes · doi:10.3390/proteomes6020014 · Cited by 21 · see citing works

Protecting Groups as a Factor of Stereocontrol in Glycosylation Reactions

Tokatly, A. I., Vinnitskiy, D. Z., Ustuzhanina, N. E., & Nifantiev, N. E. (2021) · Russian Journal of Bioorganic Chemistry · doi:10.1134/s1068162021010258 · Cited by 21 · see citing works

GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system

Yoshimura, T., Hayashi, A., Handa-Narumi, M., Yagi, H., Ohno, N., Koike, T., Yamaguchi, Y., Uchimura, K., Kadomatsu, K., Sędzik, J., et al. (2017) · Scientific Reports · doi:10.1038/srep42257 · Cited by 20 · see citing works

Encoding Asymmetry of the N-Glycosylation Motif Facilitates Glycoprotein Evolution

Williams, R., Ma, X., Schott, R. K., Mohammad, N., Ho, C., Li, C. F., Chang, B. S. W., Demetriou, M., & Dennis, J. W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086088 · Cited by 20 · see citing works

Recent advances in photoaffinity labeling strategies to capture Glycan-Protein interactions.

Babulic, J. L., González, F. V. D. L., & Capicciotti, C. J. (2024) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2024.102456 · Cited by 15 · see citing works

Tuning specificity and topology of lectins through synthetic biology

Notová, S., & Imberty, A. (2023) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2023.102275 · Cited by 19 · see citing works

Putting a cap on the glycome: Dissecting human sialyltransferase functions

Mohamed, K. A., Kruf, S., & Büll, C. (2024) · Carbohydrate Research · doi:10.1016/j.carres.2024.109242 · Cited by 19 · see citing works

Mechanistic basis of adaptive maternal effects: egg jelly water balance mediates embryonic adaptation to acidity in Rana arvalis

Shu, L., Suter, M. J. ‐., Laurila, A., & Räsänen, K. (2015) · Oecologia · doi:10.1007/s00442-015-3332-4 · Cited by 18 · see citing works

Structure and interactions of the phloem lectin (phloem protein 2) Cus17 from Cucumis sativus

Bobbili, K. B., Sivaji, N., Priya, B., Suguna, K., & Surolia, A. (2023) · Structure · doi:10.1016/j.str.2023.02.008 · Cited by 18 · see citing works

A guided tour through α-helical peptide antibiotics and their targets

Preußke, N., Sönnichsen, F. D., & Leippe, M. (2023) · Bioscience Reports · doi:10.1042/bsr20230474 · Cited by 15 · see citing works

Modulation of Cell Sialoglycophenotype: A Stylish Mechanism Adopted by Trypanosoma cruzi to Ensure Its Persistence in the Infected Host

Freire‐de‐Lima, L., da Fonseca, L. M., da Silva, V. A., da Costa, K. M., Morrot, A., Freire-de-Lima, C. G., Previato, J. O., & Mendonça‐Previato, L. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00698 · Cited by 15 · see citing works

Glyco-Engineering Cell Surfaces by Exo-Enzymatic Installation of GlcNAz and LacNAz Motifs

González, F. V. D. L., Boddington, M. E., Kofsky, J. M., Prindl, M. I., & Capicciotti, C. J. (2024) · ACS Chemical Biology · doi:10.1021/acschembio.3c00542 · Cited by 14 · see citing works

Conservation of anatomically restricted glycosaminoglycan structures in divergent nematode species

Attreed, M., Saied‐Santiago, K., & Bülow, H. E. (2016) · Glycobiology · doi:10.1093/glycob/cww037 · Cited by 14 · see citing works

Enhanced glycan nanoprofiling by weak anion exchange preparative chromatography, mild acid desialylation, and nanoliquid chromatography‐mass spectrometry with nanofluorescence detection

Kalay, H., Ambrosini, M., Chiodo, F., van Kooyk, Y., & García-Vallejo, J. J. (2013) · Electrophoresis · doi:10.1002/elps.201200657 · Cited by 14 · see citing works

Glycan Biosynthesis in Eukaryotes

Kim, C. (2022) · Springer eBooks · doi:10.1007/978-981-16-9081-5_3 · Cited by 4 · see citing works

Glycan Evolution in Response to Collaboration, Conflict, and Constraint

Springer, S. A., & Gagneux, P. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.r112.424523 · Cited by 76 · see citing works

Nothing in Glycobiology Makes Sense, except in the Light of Evolution

Varki, A. P. (2006) · Cell · doi:10.1016/j.cell.2006.08.022 · Cited by 250 · see citing works

Life is sweet: the cell biology of glycoconjugates

Broussard, A., & Boyce, M. (2019) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-04-0247 · Cited by 33 · see citing works

Evolutionary considerations in relating oligosaccharide diversity to biological function

Gagneux, P., & Varki, A. (1999) · Glycobiology · doi:10.1093/glycob/9.8.747 · Cited by 495 · see citing works