Synapses and Alzheimer's Disease

Sheng, M., Sabatini, B. L., Sudhof, T. C.·2012·Cold Spring Harbor Perspectives in Biology

Cited by (441)

Items 201–300 of 441

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    Qiujian Yu, Huimin Liu, Shaoming Sang, Lulan Chen, Yingya Zhao, Yun Wang, Chunjiu Zhong · 2018 · Biological Research
  2. Cyclin‐Dependent kinase 5 targeting prevents β‐Amyloid aggregation involving glycogen synthase kinase 3β and phosphatases
    John Fredy Castro-Álvarez, Alejandro Uribe‐Arias, Gloria Patricia Cardona‐Gómez · 2015 · Journal of Neuroscience Research
  3. Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors
    Santosh Kumar Adla, Barbora Slavı́ková, Markéta Šmídková, Eva Tloušťová, Martin Svoboda, Vojtěch Vyklický, Barbora Hrčka Krausová, Pavla Hubálková, Michaela Nekardová, Kristína Holubová et al. · 2016 · Steroids
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  5. The transcriptional landscape of Alzheimer’s disease and its association with Wnt signaling pathway
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  6. Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity
    Yi‐Chen Hsieh, Joseph M. Negri, Amy He, Richard V. Pearse, Lei Liu, Duc Minh Duong, Lori Beth Chibnik, David Alan Bennett, Nicholas T. Seyfried, Tracy L. Young‐Pearse · 2022 · Molecular Neurodegeneration
  7. Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
    Karen Perez de Arce, Adema Ribic, Dhrubajyoti Chowdhury, Katherine E. Watters, Garth J. Thompson, Basavaraju G. Sanganahalli, Elizabeth Lippard, Astrid Rohlmann, Stephen M. Strittmatter, Markus Missler et al. · 2023 · Nature Communications
  8. MRZ-99030 – A novel modulator of Aβ aggregation: II – Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice
    Gerhard Rammes, Andreas Gravius, Maarten Ruitenberg, Nico Wegener, Caroline Chambon, Kamila Sroka, Ross Jeggo, Lydia E. Staniaszek, David C. Spanswick, Eugene O‘Hare et al. · 2015 · Neuropharmacology
  9. New Insights into the Spontaneous Human Alzheimer’s Disease-Like Model Octodon degus : Unraveling Amyloid-β Peptide Aggregation and Age-Related Amyloid Pathology
    Pedro Cisternas, Juan Manuel Zolezzi, Carolina B. Lindsay, Daniela S. Rivera, Alexis N. Martinez, Francisco Bozinovic, Nibaldo C. Inestrosa · 2018 · Journal of Alzheimer s Disease
  10. A consistent map in the medial entorhinal cortex supports spatial memory
    Taylor Joseph Malone, Nai-Wen Tien, Yan Ma, Lian Cui, Shangru Lyu, Garret Wang, Duc Nguyen, Kai Zhang, Maxym Myroshnychenko, Jean Tyan et al. · 2024 · Nature Communications
  11. Early neurotransmission impairment in non-invasive Alzheimer Disease detection
    C. Peña-Bautista, I. Torres-Cuevas, M. Baquero, I. Ferrer, Lorena García, M. Vento, C. Cháfer-Pericás · 2020 · Scientific Reports
  12. Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer’s Disease
    Yangjie Jia, Xia Wang, Yanyu Chen, Wenying Qiu, Wei Ge, Chao Ma · 2021 · Molecular Neurobiology
  13. α-Synuclein Preformed Fibrils Bind to β-Neurexins and Impair β-Neurexin-Mediated Presynaptic Organization
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  14. Aβ1-42-induced dysfunction in synchronized gamma oscillation during working memory
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  15. Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases
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  16. Amyloid-β Peptides Disrupt Interactions Between VAMP-2 and SNAP-25 in Neuronal Cells as Determined by FRET/FLIM
    Nidhi Sharda, Thomas Pengo, Zengtao Wang, Karunya K. Kandimalla · 2020 · Journal of Alzheimer s Disease
  17. Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance
    João M. N. Duarte · 2023 · Biochemical Society Transactions
  18. Convergent mechanisms of microglia‐mediated synaptic dysfunction contribute to diverse neuropathological conditions
    Nicole Scott‐Hewitt, Youtong Huang, Beth Stevens · 2023 · Annals of the New York Academy of Sciences
  19. Fragile X mental retardation protein: from autism to neurodegenerative disease
    Hansen Wang · 2015 · Frontiers in Cellular Neuroscience
  20. Uncovering True Cellular Phenotypes: Using Induced Pluripotent Stem Cell-Derived Neurons to Study Early Insults in Neurodevelopmental Disorders
    James J. Fink, Eric S. Levine · 2018 · Frontiers in Neurology
  21. Peripheral apolipoprotein E proteins and their binding to LRP1 antagonize Alzheimer’s disease pathogenesis in the brain during peripheral chronic inflammation
    Hana Na, Jack B. Yang, Zhengrong Zhang, Qini Gan, Hua Tian, Ibraheem M. Rajab, Lawrence A. Potempa, Qiushan Tao, Wei Qiao Qiu · 2023 · Neurobiology of Aging
  22. Age‑dependent concomitant changes in synaptic function and GABAergic pathway in the APP/PS1 mouse model
    Tutu Oyelami, An De Bondt, Ilse Van den Wyngaert, Kirsten Van Hoorde, Luc Hoskens, Hamdy Shaban, John A. Kemp, Wilhelmus H. I. M. Drinkenburg · 2016 · Acta Neurobiologiae Experimentalis
  23. Glycogen and amyloid-beta: key players in the shift from neuronal hyperactivity to hypoactivity observed in Alzheimer′s disease?
    Ian V.J. Murray, Brittany Bass, Sarah Upson, Kamolika Roy, EmilyL Montgomery, TuulaO Jalonen · 2015 · Neural Regeneration Research
  24. Dysregulated APP expression and α-secretase processing of APP is involved in manganese-induced cognitive impairment
    Yiping Yang, Jie Zhang, Xiaobo Yang, Zhiying Li, Jian Wang, Cailing Lu, Aruo Nan, Yunfeng Zou · 2021 · Ecotoxicology and Environmental Safety
  25. Alzheimer’s disease is an inherent, natural part of human brain aging: an integrated perspective
    Isidró Ferrer · 2022 · Free Neuropathology
  26. Coexistence of Multiple Functional Variants and Genes Underlies Genetic Risk Locus 11p11.2 of Alzheimer’s Disease
    Min Xu, Qianjin Liu, Rui Bi, Yu Li, Hongli Li, Wei-Bo Kang, Zhongjiang Yan, Quanzhen Zheng, Chunli Sun, Maosen Ye et al. · 2023 · Biological Psychiatry
  27. Nattokinase: Insights into Biological Activity, Therapeutic Applications, and the Influence of Microbial Fermentation
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  28. Maternal Exposure to Di-(2-ethylhexyl) Phthalate Impairs Hippocampal Synaptic Plasticity in Male Offspring: Involvement of Damage to Dendritic Spine Development
    Dong, Jing, Fu, Hui, Fu, Yuanyuan, You, Mingdan, Li, Xudong, Wang, Chaonan, Leng, Kunkun, Wang, Yuan, Chen, Jie · 2021 · ACS Chemical Neuroscience
  29. Functional Genomics of Axons and Synapses to Understand Neurodegenerative Diseases
    Andrés Di Paolo, Joaquín Garat, Guillermo Eastman, Joaquina Farías, Federico Dajas‐Bailador, Pablo Smircich, José Roberto Sotelo-Silveira · 2021 · Frontiers in Cellular Neuroscience
  30. Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's disease
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  31. Neuromorphic Computing: A Path to Artificial Intelligence Through Emulating Human Brains
    Noah Zins, Yan Zhang, Chunxiu Yu, Hongyu An · 2023 · Springer eBooks
  32. “Olfactory Three-Needle” Enhances Spatial Learning and Memory Ability in SAMP8 Mice
    Yuan Wang, Qiang Wang, Bo Xu Ren, Ting Guo, Jing Qiang, Hui Cao, Yujie Gao, Zhibin Liu, Xinyan Gao, Bing Zhu · 2020 · Behavioural Neurology
  33. Localization of heat shock proteins in cerebral cortical cultures following induction by celastrol
    Ari M. Chow, Derek W.F. Tang, Asad Hanif, Ian R. Brown · 2014 · Cell Stress and Chaperones
  34. Identification and characterization of functional modules reflecting transcriptome transition during human neuron maturation
    Zhisong He, Qianhui Yu · 2018 · BMC Genomics
  35. Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease
    Margaret G. O’Connor, Yangping Shentu, Guan Wang, Wenting Hu, Zhendong Xu, Xiaochuan Wang, Rong Liu, Heng‐Ye Man · 2020 · iScience
  36. Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice
    Haiwang Zhang, Youssif Ben Zablah, An Liu, Dongju Lee, Haorui Zhang, Yanghong Meng, Changxi Zhou, Xingde Liu, Yiming Wang, Zhengping Jia · 2021 · Molecular Brain
  37. Inhibition of Nogo-A rescues synaptic plasticity and associativity in APP/PS1 animal model of Alzheimer's disease
    María Vázquez Pavón, Sheeja Navakkode, Lik‐Wei Wong, Sreedharan Sajikumar · 2022 · Seminars in Cell and Developmental Biology
  38. Synaptic Injury in the Thalamus Accompanies White Matter Injury in Hypoxia/Ischemia-Mediated Brain Injury in Neonatal Rats
    Na Liu, Xin Tong, Wanjie Huang, Jianhua Fu, Xindong Xue · 2019 · BioMed Research International
  39. Firing rate homeostasis counteracts changes in stability of recurrent neural networks caused by synapse loss in Alzheimer’s disease
    Claudia Bachmann, Tom Tetzlaff, Renato Duarte, Abigail Morrison · 2020 · PLoS Computational Biology
  40. Early hippocampal hyperexcitability and synaptic reorganization in mouse models of amyloidosis
    Ajit Ray, Iulia Loghinov, Vijayalakshmi Ravindranath, Alison L. Barth · 2024 · iScience
  41. Dissecting Molecular and Circuit Mechanisms for Inhibition and Delayed Response of ASI Neurons during Nociceptive Stimulus
    Min Yi Guo, Ming-Hai Ge, Michael A. Berberoglu, Jie H. S. Zhou, Long Ma, Juan Yang, Qiyan Dong, Yanni Feng, Zheng‐Xing Wu, Zhiqiang Dong · 2018 · Cell Reports
  42. OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages
    Xuping Li, Lin Wang, Matthew D. Cykowski, Tiancheng He, Timothy Liu, Joshua Chakranarayan, Andreana Laura Rivera, Hong Zhao, Suzanne Zein-Eldin Powell, Weiming Xia et al. · 2020 · EBioMedicine
  43. The β‐adrenergic hypothesis of synaptic and microglial impairment in Alzheimer's disease
    Shaomin Li · 2023 · Journal of Neurochemistry
  44. Drosophila melanogaster as a model to study age and sex differences in brain injury and neurodegeneration after mild head trauma
    Changtian Ye, Joseph A. Behnke, Katherine R. Hardin, James Q. Zheng · 2023 · Frontiers in Neuroscience
  45. Molecular mechanisms implicated in protein changes in the Alzheimer’s disease human hippocampus
    Hai Duc Nguyen, Woong-Ki Kim, Giang Huong Vu · 2024 · Mechanisms of Ageing and Development
  46. Synaptic Protein 1-Takusan Mitigates Amyloid- -Induced Synaptic Loss via Interaction with Tau and Postsynaptic Density-95 at Postsynaptic Sites
    N. Nakanishi, Scott D. Ryan, X. Zhang, Asmat Ullah Khan, T. Holland, E.-G. Cho, Xiumei Huang, Francesca‐Fang Liao, Hui Xu, Stuart A. Lipton et al. · 2013 · Journal of Neuroscience
  47. Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer’s Disease
    Yuewen Chen, Jinying Xu, Xiaopu Zhou, Saijuan Liu, Yulin Zhang, Shuangshuang Ma, Amy K.Y. Fu, Nancy Y. Ip, Yu Chen · 2019 · ACS Chemical Neuroscience
  48. miR-26b inhibits total neurite outgrowth, promotes cells apoptosis and downregulates neprilysin in Alzheimer's disease.
    Tingting Chu, Yongwei Shu, Yang Qu, Shasha Gao, Liming Zhang · 2018 · Europe PMC (PubMed Central)
  49. Alzheimer's disease: Is there a role for galectins?
    Michelle Melgarejo da Rosa, Manoela de Aguiar Ferreira, Crysvane Araújo De Oliveira Lima, Anna Claudia Santos Mendonça, Yasmim Meneses Silva, Muhammad Sharjeel, Moacyr Jesus Barreto de Melo Rêgo, Michelly Cristiny Pereira, Maíra Galdino da Rocha Pitta · 2021 · European Journal of Pharmacology
  50. HEBP1 - An early trigger for neuronal cell death and circuit dysfunction in Alzheimer’s disease
    John Jia En Chua · 2022 · Seminars in Cell and Developmental Biology
  51. Functional NMDA receptors are expressed by both AII and A17 amacrine cells in the rod pathway of the mammalian retina
    Yifan Zhou, Barbora Tencerová, Espen Hartveit, Margaret Lin Veruki · 2015 · Journal of Neurophysiology
  52. Association of SHANK Family with Neuropsychiatric Disorders: An Update on Genetic and Animal Model Discoveries
    Lily Wan, Du Liu, Wenbiao Xiao, Boxin Zhang, Xiao‐Xin Yan, Zhaohui Luo, Bo Xiao · 2021 · Cellular and Molecular Neurobiology
  53. β-Secretase BACE1 Promotes Surface Expression and Function of Kv3.4 at Hippocampal Mossy Fiber Synapses
    Stephanie Hartmann, Fang Zheng, Michele C. Kyncl, Sandra Karch, Kerstin Voelkl, Benedikt Zott, Carla D’Avanzo, Selene Lomoio, Giuseppina Tesco, Doo Yeon Kim et al. · 2018 · Journal of Neuroscience
  54. Towards developing a rhesus monkey model of early Alzheimer's disease focusing on women's health
    Danielle Beckman, John H. Morrison · 2021 · American Journal of Primatology
  55. Hydroxymethyl bioisosteres of phenolic GluN2B-selective NMDA receptor antagonists: Design, synthesis and pharmacological evaluation
    Louisa Temme, Bastian Frehland, Dirk Schepmann, Dina Robaa, Wolfgang Sippl, Bernhard Wünsch · 2017 · European Journal of Medicinal Chemistry
  56. Calcitonin native prefibrillar oligomers but not monomers induce membrane damage that triggers NMDA-mediated Ca2+-influx, LTP impairment and neurotoxicity
    Marcello Belfiore, Ida Cariati, Andrea Matteucci, Lucia Gaddini, Gianfranco Macchia, Raoul Fioravanti, Claudio Frank, Virginia Tancredi, Giovanna D’Arcangelo, Marco Diociaiuti · 2019 · Scientific Reports
  57. Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice
    Cecilia Skoug, Cecilia Holm, João M. N. Duarte · 2022 · Journal of Lipid Research
  58. Cholinergic activity is essential for maintaining the anterograde transport of Choline Acetyltransferase in Drosophila
    Swagata Dey, Krishanu Ray · 2018 · Scientific Reports
  59. β-amyloid pathology is not associated with depression in a large community sample autopsy study
    Nanci Moreira Saldanha, Cláudia Kimie Suemoto, Roberta Diehl Rodriguez, Renata Elaine Paraízo Leite, Camila Fernandes Nascimento, Renata Eloah de Lucena Ferretti‐Rebustini, Magnólia Moreira da Silva, Carlos Augusto Pasqualucci, Ricardo Nitríni, Wilson Jacob Filho et al. · 2020 · Journal of Affective Disorders
  60. Accumulated BCAAs and BCKAs contribute to the HFD-induced deterioration of Alzheimer's disease via a dysfunctional TREM2-related reduction in microglial β-amyloid clearance
    Yang Yang, Guanjin Shi, Y. Ge, Shan-Shan Huang, Ning-Ning Cui, L. Tan, Rui Liu, Xue-Feng Yang · 2024 · Journal of Neuroinflammation
  61. Long-term exposure to high glucose induces changes in the expression of AMPA receptor subunits and glutamate transmission in primary cultured cortical neurons
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  62. Altered pain sensitivity in 5×familial Alzheimer disease mice is associated with dendritic spine loss in anterior cingulate cortex pyramidal neurons
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  64. Amyloid –β pathology in Alzheimer’s disease: A nano delivery approach
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  65. Impairments in endogenous AMPA receptor dynamics correlates with learning deficits in Alzheimer’s disease model mice
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  66. The therapeutic prospects and challenges of human neural stem cells for the treatment of Alzheimer's Disease
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  67. Alterations in spontaneous delta and gamma activity might provide clues to detect changes induced by amyloid‐β administration
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  68. Synaptic Organizers in Alzheimer’s Disease: A Classification Based on Amyloid-β Sensitivity
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  69. Cerebrospinal Fluid Synaptosomal-Associated Protein 25 Levels in Patients with Alzheimer’s Disease: A Meta-Analysis
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  70. Genome‐wide association studies identify novel loci in rapidly progressive Alzheimer's disease
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  71. Etersalate prevents the formations of 6Aβ16-22 oligomer: An in silico study
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  72. Presenilin and APP Regulate Synaptic Kainate Receptors
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  76. Partial Destabilization of Amyloid-β Protofibril by Methionine Photo-Oxidation: A Molecular Dynamic Simulation Study
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  78. Association between systemic rheumatic diseases and dementia risk: A meta-analysis
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  79. Altered exocytosis in chromaffin cells from mouse models of neurodegenerative diseases
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  80. The Role of Long Noncoding RNAs in Diabetic Alzheimer’s Disease
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  86. Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer's disease
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  88. Rare Variants and Transcriptomics in Alzheimer disease
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  89. Biomarkers of Activity-Dependent Plasticity and Persistent Enhancement of Synaptic Transmission in Alzheimer Disease: A Review of the Current Status
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  91. Brain metabolite clearance: impact on Alzheimer’s disease
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  92. Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses
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  93. Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries
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  94. The role of microglia in the prion-like transmission of protein aggregates in neurodegeneration
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  95. Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates
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  96. Advances in Neural Signal Processing
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  98. ATP-ases of synaptic plasma membranes in striatum: Enzymatic systems for synapses functionality by in vivo administration of l-acetylcarnitine in relation to Parkinson’s Disease
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  99. Combined loss of brevican, neurocan, tenascin-C and tenascin-R leads to impaired fear retrieval due to perineuronal net loss
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  100. Alpha‐Ketoglutarate Ameliorates Synaptic Plasticity Deficits in APP / PS1 Mice Model of Alzheimer's Disease
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