Synapses and Alzheimer's Disease

Sheng, M., Sabatini, B. L., Sudhof, T. C.·2012·Cold Spring Harbor Perspectives in Biology

Cited by (441)

Items 101–200 of 441

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  2. Common Factors in Neurodegeneration: A Meta-Study Revealing Shared Patterns on a Multi-Omics Scale
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  3. Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease
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  4. Treatment of Alzheimer’s Disease: The Legacy of the Cholinergic Hypothesis, Neuroplasticity, and Future Directions
    John Wesson Ashford · 2015 · Journal of Alzheimer s Disease
  5. Ca2+-permeable AMPA receptor: A new perspective on amyloid-beta mediated pathophysiology of Alzheimer's disease
    Garry Whitehead, Philip L. Regan, Daniel J. Whitcomb, Kwangwook Cho · 2016 · Neuropharmacology
  6. PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease
    Giralt, Albert, de Pins, Benoit, Cifuentes-Díaz, Carmen, López-Molina, Laura, Farah, Amel Thamila, Tible, Marion, Deramecourt, Vincent, Arold, Stefan T, Ginés, Silvia, Hugon, Jacques et al. · 2018 · Experimental Neurology
  7. The two faces of synaptic failure in AppNL-G-F knock-in mice
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  8. Long non-coding RNAs in brain development, synaptic biology, and Alzheimer’s disease
    Changhua Shi, Ling Zhang, Chuan Qin · 2017 · Brain Research Bulletin
  9. Identification of Circulating miR-125b as a Potential Biomarker of Alzheimer’s Disease in APP/PS1 Transgenic Mouse
    Honghai Hong, Yang Li, Baochang Su · 2017 · Journal of Alzheimer s Disease
  10. Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition
    Park, Jong-Chan, Han, Sun-Ho, Cho, Hyun Jin, Byun, Min Soo, Yi, Dahyun, Choe, Young Min, Kang, Seokjo, Jung, Eun Sun, Won, Su Jin, Kim, Eun Hye et al. · 2017 · Alzheimer's Research & Therapy
  11. Evidence for altered dendritic spine compartmentalization in Alzheimer’s disease and functional effects in a mouse model
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  12. Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
    Timothy J. Hark, Nalini R. Rao, Charlotte Castillon, Tamara Basta, Samuel N. Smukowski, Huan Bao, Arun Upadhyay, Ewa K. Bomba-Warczak, Toshihiro Nomura, Eileen T O'Toole et al. · 2020 · Cell Systems
  13. Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum BDNF Levels in Healthy Older Adults: A Randomized Controlled Intervention Study
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  14. Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer’s disease mouse model
    Laura K. Hamilton, Gaël Moquin‐Beaudry, Chenicka Lyn Mangahas, Federico Pratesi, Myriam Aubin, Anne Aumont, Sandra E. Joppé, Alexandre Légiot, Annick Vachon, Mélanie Plourde et al. · 2022 · Nature Communications
  15. Autophagy interaction with herpes simplex virus type-1 infection
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  16. BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease
    Burke, Rebecca M., Norman, Timothy A., Haydar, Tarik F., Slack, Barbara E., Leeman, Susan E., Blusztajn, Jan Krzysztof, Mellott, Tiffany J. · 2013 · Proceedings of the National Academy of Sciences
  17. Epigenetic regulation by G9a/ GLP complex ameliorates amyloid‐beta 1‐42 induced deficits in long‐term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons
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  18. Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit
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  20. Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice
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  22. Caspase‐6 as a novel early target in the treatment of Alzheimer's disease
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  23. Role of Liver X Receptor in AD Pathophysiology
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  24. Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model
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  25. Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice
    Claire S. Durrant, Michael P. Coleman · 2016 · Molecular Neurodegeneration
  26. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease
    Santiago V. Salazar, Christopher Gallardo, Adam C. Kaufman, Charlotte S. Herber, Laura T. Haas, Sophie Robinson, Jean C. Manson, Michael K. Lee, Stephen M. Strittmatter · 2017 · Journal of Neuroscience
  27. Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway
    Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Qinjie Li, Ya Miao · 2018 · International Journal of Molecular Medicine
  28. Tau acts as a mediator for<scp>A</scp>lzheimer's disease‐related synaptic deficits
    Liao, Dezhi, Miller, Eric C., Teravskis, Peter J. · 2014 · European Journal of Neuroscience
  29. Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule
    Vojtěch Vyklický, Barbora Hrčka Krausová, Jiří Černý, Aleš Balík, Martin Zapotocky, Marián Novotný, Katarína Hemelíková, Tereza Smejkalová, Martina Kaniaková, Miloslav Kořı́nek et al. · 2015 · Scientific Reports
  30. Fornical Closed-Loop Stimulation for Alzheimer’s Disease
    Sühan Senova, Antoine Chaillet, Andrés M. Lozano · 2018 · Trends in Neurosciences
  31. Altered neural cell junctions and ion-channels leading to disrupted neuron communication in Parkinson’s disease
    Choudhury, Saptamita Paul, Bano, Sarika, Sen, Srijon, Suchal, Kapil, Kumar, Saroj, Nikolajeff, Fredrik, Dey, Sanjay Kumar, Sharma, Vaibhav · 2022 · npj Parkinson's Disease
  32. Alzheimer’s disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs
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  33. On the research of time past: the hunt for the substrate of memory
    Bridget N. Queenan, Tomás J. Ryan, Michael S. Gazzaniga, Charles Randy Gallistel · 2017 · Annals of the New York Academy of Sciences
  34. Sensory processing deficits and related cortical pathological changes in Alzheimer’s disease
    Zhang, Nicole K., Zhang, Selena K., Zhang, Li I., Tao, Huizhong W., Zhang, Guang-Wei · 2023 · Frontiers in Aging Neuroscience
  35. VEGF counteracts amyloid-β-induced synaptic dysfunction
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  36. Promising Role of Neuromodulation in Predicting the Progression of Mild Cognitive Impairment to Dementia
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  37. Regulation of GABAergic synapse development by postsynaptic membrane proteins
    Wei Lü, Samantha Bromley‐Coolidge, Jun Li · 2016 · Brain Research Bulletin
  38. Future Therapeutics in Alzheimer’s Disease: Development Status of BACE Inhibitors
    Genevieve M. Evin · 2016 · BioDrugs
  39. Bioactive human Alzheimer brain soluble Aβ: pathophysiology and therapeutic opportunities
    Shaomin Li, Andrew M. Stern · 2022 · Molecular Psychiatry
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    Claudia García‐Rodríguez, Paula Mujica, Javiera Illanes-González, Araceli López, Camilo Vargas, Juan Carlos Sáez, Arlek M. González‐Jamett, Álvaro O. Ardiles · 2023 · Biomedicines
  41. Age-related alterations in human neocortical plasticity
    Meg J. Spriggs, Claire J. Cadwallader, Jordan P. Hamm, Lynette J. Tippett, Ian J. Kirk · 2016 · Brain Research Bulletin
  42. Proteomic analysis of postsynaptic density in Alzheimer's Disease
    Jianying Zhou, Drew R. Jones, Duc Minh Duong, Allan I. Levey, James J. Lah, Junmin Peng · 2013 · Clinica Chimica Acta
  43. Disruption of a Neural Microcircuit in the Rod Pathway of the Mammalian Retina by Diabetes Mellitus
    Áurea Castilho, António Francisco Ambrósio, Espen Hartveit, Margaret Lin Veruki · 2015 · Journal of Neuroscience
  44. LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses
    Wang, Shao-hua, Huang, Yan, Yuan, Yang, Xia, Wen-qing, Wang, Pin, Huang, Rong · 2014 · Lipids in Health and Disease
  45. Stress-Induced Synaptic Dysfunction and Neurotransmitter Release in Alzheimer’s Disease: Can Neurotransmitters and Neuromodulators be Potential Therapeutic Targets?
    Saurabh Kumar Jha, Niraj Kumar Jha, Dhiraj Kumar, Renu Sharma, Abhishek Shrivastava, Rashmi K. Ambasta, Pravir Kumar · 2016 · Journal of Alzheimer s Disease
  46. Soluble tau aggregates inhibit synaptic long-term depression and amyloid β-facilitated LTD in vivo
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  47. Stereo-seq of the prefrontal cortex in aging and Alzheimer’s disease
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  48. Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression
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  49. Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of A lzheimer's Disease
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  50. Recent Developments in Understanding Brain Aging: Implications for Alzheimer’s Disease and Vascular Cognitive Impairment
    Ferenc Deák, Willard M. Freeman, Zoltan I. Ungvari, Anna Csiszár, William Edmund Sonntag · 2015 · The Journals of Gerontology Series A
  51. PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy
    Joseph Benetatos, Rachel E. Bennett, Harrison Tudor Evans, Sevannah A. Ellis, Bradley T. Hyman, Liviu‐Gabriel Bodea, Jürgen Götz · 2020 · Acta Neuropathologica
  52. d-Polyglutamine Amyloid Recruits l-Polyglutamine Monomers and Kills Cells
    Karunakar Kar, Irene Arduini, Kenneth W. Drombosky, Patrick C.A. van der Wel, Ronald B. Wetzel · 2013 · Journal of Molecular Biology
  53. Modulation of neurotrophic factors in the treatment of dementia, stroke and TBI: Effects of Cerebrolysin
    K. Rejdak, H. Sienkiewicz-Jarosz, P. Bieńkowski, A. Alvarez · 2023 · Medicinal research reviews (Print)
  54. Amyloid‐β oligomers interact with neurexin and diminish neurexin‐mediated excitatory presynaptic organization
    Naito, Yusuke, Tanabe, Yuko, Lee, Alfred Kihoon, Hamel, Edith, Takahashi, Hideto · 2017 · Scientific Reports
  55. Alzheimer’s disease: amyloid-based pathogenesis and potential therapies
    Yixiu Zhou, Yuhui Sun, Quanhong Ma, Yaobo Liu · 2018 · Cell Stress
  56. X-ray Absorption Spectroscopy Investigations of Copper(II) Coordination in the Human Amyloid β Peptide
    Kelly L. Summers, Kevin M. Schilling, Graham P. Roseman, Kate A. Markham, Natalia V. Dolgova, Thomas Kröll, Dimosthenis Sokaras, Glenn L. Millhauser, Ingrid J. Pickering, Graham Neil George · 2019 · Inorganic Chemistry
  57. Dysfunction of the ubiquitin ligase E3A Ube3A/E6-AP contributes to synaptic pathology in Alzheimer’s disease
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  58. Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells
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  59. Synaptic Communication Engineering for Future Cognitive Brain–Machine Interfaces
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  60. Advances in stem cell therapy in Alzheimer’s disease: a comprehensive clinical trial review
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  61. Natural Phyto-Antioxidant Albumin Nanoagents to Treat Advanced Alzheimer’s Disease
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  62. Fmr1 KO and Fenobam Treatment Differentially Impact Distinct Synapse Populations of Mouse Neocortex
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  71. Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis
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  93. Effect of genetic polymorphisms on Alzheimer’s disease treatment outcomes: an update
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  94. Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis
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  100. Role of ASIC1a in Aβ-induced synaptic alterations in the hippocampus
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