Proteolytic Degradation of Amyloid -Protein

Cited by (369)

Items 201–300 of 369

1. Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells
   J. Chung, Geetika Phukan, David Vergote, A. Mohamed, Mahua Maulik, Miranda Stahn, Robert J. Andrew, Gopal Thinakaran, E Chaves, Satyabrata Kar · 2018 · Molecular and Cellular Biology
2. An inorganic overview of natural Aβ fragments: Copper(II) and zinc(II)-mediated pathways
   V. Lanza, F. Bellia, E. Rizzarelli · 2018 · Coordination chemistry reviews
3. The function of the co-chaperone ERdj4 in diverse (patho-)physiological conditions
   Lea Daverkausen-Fischer, Felicitas Pröls · 2021 · Cellular and Molecular Life Sciences
4. Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42
   Claire A. Krasinski, Valerie A. Ivancic, Qiuchen Zheng, Donald E. Spratt, Noel D. Lazo · 2018 · ACS Omega
5. The Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis
   Amanda J. Stock, Anne Kasus‐Jacobi, Jonathan D. Wren, Virginie Helle Sjoelund, Glenn D. Prestwich, Heloise Anne Pereira · 2016 · PLoS ONE
6. Metal homeostasis disturbances in neurodegenerative disorders, with special emphasis on Creutzfeldt-Jakob disease – Potential pathogenetic mechanism and therapeutic implications
   Yutaka Nakagawa, Shizuo Yamada · 2019 · Pharmacology & Therapeutics
7. Medroxyprogesterone Acetate Impairs Amyloid Beta Degradation in a Matrix Metalloproteinase-9 Dependent Manner
   Porter, Keyana N., Sarkar, Saumyendra N., Dakhlallah, Duaa A., Vannoy, Mya E., Quintana, Dominic D., Simpkins, James W. · 2020 · Frontiers in Aging Neuroscience
8. Cardiolipin released by microglia can act on neighboring glial cells to facilitate the uptake of amyloid-β (1–42)
   Tyler J. Wenzel, Taryn E. Murray, Benjamin Noyovitz, Kamal Narayana, Taylor E. Gray, Jennifer M. Le, Jim He, Svetlana Simtchouk, Julien Gibon, Jane Alcorn et al. · 2022 · Molecular and Cellular Neuroscience
9. Alleviating the unwanted effects of oxidative stress on Aβ clearance: a review of related concepts and strategies for the development of computational modelling
   Sarawoot Somin, Don Kulasiri, Sandhya Samarasinghe · 2023 · Translational Neurodegeneration
10. Immunotherapy in Alzheimer’s disease: focusing on the efficacy of gantenerumab on amyloid-β clearance and cognitive decline
    Ali Azargoonjahromi · 2024 · Journal of Pharmacy and Pharmacology
11. Effects of cholesterol transport inhibitor U18666A on APP metabolism in rat primary astrocytes
    Hongyan Yang, Yanlin Wang, Satyabrata Kar · 2017 · Glia
12. Racemization in Post-Translational Modifications Relevance to Protein Aging, Aggregation and Neurodegeneration: Tip of the Iceberg
    Victor V. Dyakin, Thomas Wısnıewskı, Ábel Lajtha · 2021 · Symmetry
13. Experimental approaches for altering the expression of Abeta‐degrading enzymes
    David A. Loeffler · 2023 · Journal of Neurochemistry
14. Dysfunction of different cellular degradation pathways contributes to specific β‐amyloid42‐induced pathologies
    Xuan‐Ru Ji, Kuan‐Chung Cheng, Yu‐Ru Chen, Tzu‐Yu Lin, Chun Hei Antonio Cheung, Chia‐Lin Wu, Hsueh‐Cheng Chiang · 2017 · The FASEB Journal
15. Deletion of miR-33, a regulator of the ABCA1–APOE pathway, ameliorates neuropathological phenotypes in APP/PS1 mice
    Tate, Mason, Wijeratne, H. R. Sagara, Kim, Byungwook, Philtjens, Stéphanie, You, Yanwen, Lee, Do‐Hun, Gutierrez, Daniela A., Sharify, Daniel, Wells, Megan, Perez‐Cardelo, Magdalena et al. · 2024 · Alzheimer's & Dementia
16. Targeting lysyl-oxidase (LOX) may facilitate intramural periarterial drainage for the treatment of Alzheimer's disease
    Louise Kelly, Matthew MacGregor Sharp, Isabelle Thomas, Christopher Brown, Matthew Schrag, Lissa Ventura Antunes, Elena Solopova, José Martínez‐González, Cristina Rodrı́guez, Roxana Octavia Carare · 2023 · Cerebral Circulation - Cognition and Behavior
17. Prospects of antidiabetic drugs in the treatment of neurodegenerative disease
    Lidan Hu, Wenmin Wang, Xiangjun Chen, Guannan Bai, Liangjian Ma, Xin Yang, Qiang Shu, Xuekun Li · 2024 · Brain‐X
18. Navigating the Landscape of Plasma Biomarkers in Alzheimer's Disease: Focus on Past, Present, and Future Clinical Applications
    Sarrah E. Ankeny, Julia R. Bacci, Boris Decourt, Marwan Noel Sabbagh, Michelle M. Mielke · 2024 · Neurology and Therapy
19. The Effect of Aβ1-42 Oligomers on APP Processing and Aβ1-40 Generation in Cultured U-373 Astrocytes
    Dimitar Ourdev, Bahram V. Foroutanpay, Yanlin Wang, Satyabrata Kar · 2015 · Neurodegenerative Diseases
20. Simulated Interactions between Endothelin Converting Enzyme and Aβ Peptide: Insights into Subsite Recognition and Cleavage Mechanism
    Sagar H. Barage, C. B. Jalkute, M. Dhanavade, K. Sonawane · 2014 · International Journal of Peptide Research and Therapeutics
21. Maintenance of Amyloid β Peptide Homeostasis by Artificial Chaperones Based on Mixed‐Shell Polymeric Micelles
    Fan Huang, Jianzu Wang, Aoting Qu, Liangliang Shen, Jinjian Liu, Jianfeng Liu, Zhenkun Zhang, Yingli An, Linqi Shi · 2014 · Angewandte Chemie
22. Newfound effect of N-acetylaspartate in preventing and reversing aggregation of amyloid-beta in vitro
    Jean-Pierre Dollé, Jeffrey M. Rodgers, Kevin D. Browne, Thomas Troxler, Feng Gai, Douglas H. Smith · 2018 · Neurobiology of Disease
23. Effect of blood collection tube containing protease inhibitors on the pre‐analytical stability of Alzheimer's disease plasma biomarkers
    Yijun Chen, Xuemei Zeng, Jihui L. Diaz, Anuradha Sehrawat, Tara K Lafferty, James J. Boslett, William Edward Klunk, Tharick Ali Pascoal, Victor L. Villemagne, Ann D. Cohen et al. · 2024 · Journal of Neurochemistry
24. N-Terminal Truncated Aβ4-42 Is a Substrate for Neprilysin Degradation in vitro and in vivo
    Karen Annette Hornung, Silvia Zampar, Nadine Engel, Hans‐Wolfgang Klafki, Thomas Liepold, Thomas A. Bayer, Jens Wiltfang, Olaf Jahn, Oliver Wirths · 2019 · Journal of Alzheimer s Disease
25. Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: implications for Alzheimer’s disease
    Lauer, Anna A., Mett, Janine, Janitschke, Daniel, Thiel, Andrea, Stahlmann, Christoph P., Bachmann, Cornel M., Ritzmann, Felix, Schrul, Bianca, Müller, Ulrike C., Stein, Reuven et al. · 2020 · Aging Cell
26. Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP / PS 1 transgenic mice
    Shaowu Cheng, Willayat Yousuf Wani, David A. Hottman, Angela Jeong, Dongfeng Cao, Kyle J. LeBlanc, Paul Säftig, Jianhua Zhang, Ling Li · 2017 · Journal of Neurochemistry
27. Exceptional in vivo catabolism of neurodegeneration-related aggregates
    Zsolt Datki, Zita Galik-Olah, Tibor Hortobágyi, Lilla Mácsai, Katalin Zsuga, Lívia Fülöp, Zsolt Bozsó, Bence Gálik, Éva Ács, Angéla Földi et al. · 2018 · Acta Neuropathologica Communications
28. Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme
    Valerie A. Ivancic, Claire A. Krasinski, Qiuchen Zheng, Rebecca J. Meservier, Donald E. Spratt, Noel D. Lazo · 2018 · Bioscience Reports
29. MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets
    Fatih Demir, Jayachandran N. Kizhakkedathu, Markus Matthias Rinschen, Pitter F. Huesgen · 2021 · Analytical Chemistry
30. Enhanced Aβ1–40 Production in Endothelial Cells Stimulated with Fibrillar Aβ1–42
    Jayakumar Rajadas, Wenchao Sun, Hai Li, Mohammed Inayathullah, Damiano M. Cereghetti, Aaron Tan, Valéria de Mello Coelho, Francis J. Chrest, John W. Kusiak, Wanli Wei Smith et al. · 2013 · PLoS ONE
31. Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis
    Irem Ulku, Filip Liebsch, Sigvard Åkerman, Jana Felicitas Schulz, Luka Kulic, Christoph Höck, Claus U. Pietrzik, Alessandro Di Spiezio, Gopal Thinakaran, Paul Säftig et al. · 2023 · Scientific Reports
32. Numerical and Analytical Simulation of the Growth of Amyloid-β Plaques
    Andrey V. Kuznetsov · 2024 · Journal of Biomechanical Engineering
33. Activation of the γ-secretase complex and presence of γ-secretase-activating protein may contribute to Aβ42 production in sporadic inclusion-body myositis muscle fibers
    Anna Nogalska, Carla D’Agostino, W. King Engel, Valerie Askanas · 2012 · Neurobiology of Disease
34. Age and Its Association with Low Insulin and High Amyloid-β Peptides in Blood
    Huajie Li, Haihao Zhu, Max Wallack, Mkaya Mwamburi, Samer O. Abdul‐Hay, Malcolm A. Leissring, Wei Qiao Qiu · 2015 · Journal of Alzheimer s Disease
35. The Role of Aging in Alzheimer’s Disease
    Geoffrey A. Kerchner, Tony Wyss‐Coray · 2015 · Springer eBooks
36. Circulating adiponectin levels, expression of adiponectin receptors, and methylation of adiponectin gene promoter in relation to Alzheimer’s disease
    Aiym Kaiyrlykyzy, Bauyrzhan A. Umbayev, Abdul‐Razak Masoud, Aida Baibulatova, Andrey Tsoy, Farkhad Olzhayev, Dinara Alzhanova, Gulnaz Zholdasbekova, Kairat Davletov, Ainur R. Akilzhanova et al. · 2022 · BMC Medical Genomics
37. Systematic review of amyloid-beta clearance proteins from the brain to the periphery: implications for Alzheimer’s disease diagnosis and therapeutic targets
    Le-Tian Huang, Mingyue Liu, Ze Li, Bing Li, Jiahe Wang, Ke Zhang · 2025 · Neural Regeneration Research
38. Nanomedicine-Driven Therapeutic Interventions of Autophagy and Stem Cells in The Management of Alzheimer’s Disease
    Fahad Saad Alhodieb, Mohammad Akhlaquer Rahman, Muhammad Abul Barkat, Abdulkareem Ali Alanezi, Harshita Abul Barkat, Hazrina Ab. Hadi, Ranjit Kumar Harwansh, Vineet Mittal · 2023 · Nanomedicine
39. Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose‐conjugated beta sheet breaker peptides
    Giuseppe Di Natale, Stefania Zimbone, Francesco Bellia, Marianna Flora Tomasello, Maria Laura Giuffrida, Giuseppe Pappalardo, Enrico Rizzarelli · 2018 · Peptide Science
40. Recent advances in pre-clinical diagnosis of Alzheimer’s disease
    John Zhou, Marc Benoit, Md Golam Sharoar · 2021 · Metabolic Brain Disease
41. Fluids and flows in brain cancer and neurological disorders
    Peng Jin, Jennifer M. Munson · 2022 · WIREs Mechanisms of Disease
42. Anticoagulants inhibit proteolytic clearance of plasma amyloid beta
    Lu Yang, Arup Bhattacharya, Yun Li, Yuesheng Zhang · 2017 · Oncotarget
43. Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer’s disease
    Lauren Owens, Alexandre Benedetto, Neil Dawson, Christopher J. Gaffney, Edward T. Parkin · 2021 · Brain Research
44. Unveiling Brain Aβ Heterogeneity Through Targeted Proteomic Analysis
    Agueda A. Rostagno, Thomas A. Neubert, Jorge A. Ghiso · 2018 · Methods in molecular biology
45. Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains
    Mehrdad Falamarzi Askarani, Fei Fang, Scott Counts, Liangliang Sun · 2025 · PROTEOMICS
46. Effects of DHA (omega-3 fatty acid) and estradiol on amyloid β-peptide regulation in the brain
    Didier Majou, Anne-Lise Dermenghem · 2023 · Brain Research
47. Interlinking diabetes and Alzheimer's disease: A pathway through medicinal plant-based treatments
    Sandesh Kumar Pattanaik, Prajapati Manisha Anil, Sudipta Jena, Diptirani Rath · 2025 · Journal of Ethnopharmacology
48. Combination of Carthamus tinctorius L. seed and Taraxacum coreanum exerts synergistic effects on learning and memory function by regulating metabolism of amyloid beta in mice
    Mei Tong He, Ji-Hyun Kim, Ji Hyun Kim, Chan Hum Park, Eun Ju Cho · 2020 · Journal of Functional Foods
49. Biomimetically Engineered Amyloid-Shelled Gold Nanocomplexes for Discovering α-Synuclein Oligomer-Degrading Drugs
    Dongtak Lee, Hyo Gi Jung, Dongsung Park, Junho Bang, Ji Hye Hong, Sang Won Lee, Seokbeom Roh, Jae Won Jang, Yong-Hwan Kim, Kyo Seon Hwang et al. · 2022 · ACS Applied Materials & Interfaces
50. Protective Potential of β-Hydroxybutyrate against Glucose-Deprivation-Induced Neurotoxicity Involving the Modulation of Autophagic Flux and the Monomeric Aβ Level in Neuro-2a Cells
    Yi‐Fen Chiang, Ngan Thi Kim Nguyen, Shih‐Min Hsia, Hsin-Yuan Chen, Shyh‐Hsiang Lin, Ching-I Lin · 2023 · Biomedicines
51. Apolipoprotein E receptor pathways in Alzheimer disease
    Vanessa Schmidt, Anne-Sophie Carlo, Thomas E. Willnow · 2014 · WIREs Systems Biology and Medicine
52. Identification of amyloid beta mid-domain fragments in human cerebrospinal fluid.
    Magnus Røgeberg, M. Wettergreen, L. Nilsson, T. Fladby · 2015 · Biochimie
53. Sodium phenylbutyrate reverses lysosomal dysfunction and decreases amyloid-β42 in an in vitro-model of inclusion-body myositis
    Anna Nogalska, Carla D’Agostino, W. King Engel, Valerie Askanas · 2014 · Neurobiology of Disease
54. Inhibition of insulin-degrading enzyme in human neurons promotes amyloid-β deposition
    Helen A. Rowland, S. Moxon, Nicola J. Corbett, Kelsey A. Hanson, Kate Fisher, K. Kellett, Nigel M. Hooper · 2023 · Neuronal Signaling
55. Isobaric Quantification of Cerebrospinal Fluid Amyloid-β Peptides in Alzheimer’s Disease: C-Terminal Truncation Relates to Early Measures of Neurodegeneration
    Magnus Røgeberg, Ina S. Almdahl, Marianne Wettergreen, Lars N. G. Nilsson, Tormod Fladby · 2015 · Journal of Proteome Research
56. Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via circRNAs as a potential therapeutic approach for neurodegenerative diseases
    Rabea Basri, Faryal Mehwish Awan, Burton B. Yang, Usman Ayub Awan, Ayesha Obaid, Anam Naz, Aqsa Ikram, Suliman Khan, Ijaz ul Haq, Sadiq Noor Khan et al. · 2023 · Frontiers in Molecular Neuroscience
57. Antibody-guided proteases enable selective and catalytic degradation of challenging therapeutic targets
    Matthew G. Romei, Brandon C. Leonard, Ingrid Kim, Hok Seon Kim, Greg A. Lazar · 2023 · Journal of Biological Chemistry
58. Effect of diffusivity of amyloid beta monomers on the formation of senile plaques
    Andrey V. Kuznetsov · 2024 · Mathematical Medicine and Biology A Journal of the IMA
59. The Other Side of Alzheimer’s Disease: Influence of Metabolic Disorder Features for Novel Diagnostic Biomarkers
    Chiara Argentati, Ilaria Tortorella, Martina Bazzucchi, Carla Emiliani, Francesco Morena, Sabata Martino · 2020 · Journal of Personalized Medicine
60. Suppression of amyloid‐β secretion from neurons by cis ‐9, trans ‐11‐octadecadienoic acid, an isomer of conjugated linoleic acid
    Saori Hata, Kazunori Kikuchi, Kuniyuki Kano, Haruka Saito, Yuriko Sobu, Shoichi Kinoshita, Takashi Saito, Takaomi C. Saido, Yoshitake Sano, Hidenori Taru et al. · 2021 · Journal of Neurochemistry
61. Vasoactive neuropeptides and Alzheimer’s disease: a systematic review focusing on calcitonin gene-related peptide
    Giulio Papiri, Simona Luzzi, Matteo Marcucci, Arianna Vignini · 2021 · Journal of Integrative Neuroscience
62. LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice
    Sophie K. Stukas, Lita A. Freeman, Michael Lee, Anna Wilkinson, Alice Ossoli, Boris L. Vaisman, Stephen J. Demosky, Jeniffer Y. Chan, Veronica Hirsch‐Reinshagen, Alan Thomas Remaley et al. · 2014 · Journal of Lipid Research
63. Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment
    Nicole G. Metzendorf, Ana Godec, Alex Petrovic, Aikaterini Chourlia, Antonino Napoleone, Stina Syvänen, Fadi Rofo, Greta Hultqvist · 2025 · Biomedicine & Pharmacotherapy
64. Postmenopausal sarcopenia and Alzheimer's disease: The interplay of mitochondria, insulin resistance, and myokines
    Fardous Farhana, Most Arifa Sultana, Raksa Andalib Hia, Vijay K. Hegde · 2025 · Neuroscience & Biobehavioral Reviews
65. Effect of icariin in a rat model of colchicine-induced cognitive deficit: role of β - amyloid proteolytic enzymes
    Eman Magdy Omar, Soha F. Elatrebi, Nada A.H. Soliman, Amira M. Omar, Eman A. Allam · 2022 · Nutritional Neuroscience
66. Astrocytic functions and lipid metabolism: Correlations and therapeutic targets in Alzheimer's disease and glioblastoma
    Xu Zhang, Rongrong Gao, Liuke Yang, Youwei Zhu, Tiancheng Zhang, Xiaorong Shen, Wenwen Gu, Long Yang, Shenjie Peng · 2024 · Clinical and Translational Discovery
67. Association of Genes Involved in the Metabolic Pathways of Amyloid-β and Tau Proteins With Sporadic Late-Onset Alzheimer’s Disease in the Southern Han Chinese Population
    Xuewen Xiao, Bin Jiao, Xinxin Liao, Weiwei Zhang, Zhenhua Yuan, Lina Guo, Xin Wang, Lu Zhou, Xixi Liu, Xinxiang Yan et al. · 2020 · Frontiers in Aging Neuroscience
68. A study from structural insight to the antiamyloidogenic and antioxidant activities of flavonoids: scaffold for future therapeutics of Alzheimer’s disease
    Madhu Sudan Dutta · 2022 · Medicinal Chemistry Research
69. A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site
    E. Futai, H. Kawasaki, Shinichi Sato, Khadija Daoudi, Masafumi Hidaka, T. Tomita, T. Ogawa · 2023 · Toxins
70. Functional amyloid formation in LPS activated cells from invertebrates to vertebrates
    Annalisa Grimaldi, Gianluca Tettamanti, Rossana Girardello, Laura Pulze, Roberto Valvassori, Davide Malagoli, Enzo Ottaviani, Magda de Eguileor · 2014 · Invertebrate survival journal
71. Neprilysin Inhibitors as a New Approach in the Treatment of Right Heart Failure in the Course of Chronic Obstructive Pulmonary Disease. Response to the Letter of Siniorakis et al.
    Maciej Liczek, Iga Panek, Piotr Damiański, Olga Jęczeń, Jędrzej Jaźwiec, Piotr Kuna, Michał Panek · 2018 · Advances in respiratory medicine
72. Numerical Simulations Reveal Complementary Function of Blood-Brain Barrier and Glymphatic Transport in the Brain
    Reza Yousofvand, Jeffrey Tithof · 2025 · Physical Review Letters
73. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer’s Disease
    Xuesong Chen, John F. Wagener, Othman Ghribi, Jonathan D. Geiger · 2016 · Frontiers in Aging Neuroscience
74. Hypoxia and Inflammation as a Consequence ofβ-Fibril Accumulation: A Perspective View for New Potential Therapeutic Targets
    Matteo Antonio Russo, Carlo Tomino, Enza Vernucci, Federica Limana, Luigi Sansone, Andrea Frustaci, Marco Tafani · 2019 · Oxidative Medicine and Cellular Longevity
75. Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
    H. B. Peng, K. Noh, Sophie R. Pan, V. Saldivia, Sylvia Serson, Anja Toscan, I. D. de Lannoy, K. Pang · 2020 · Drug Metabolism And Disposition
76. Aβ degradation—the inside story
    Malcolm A. Leissring · 2014 · Frontiers in Aging Neuroscience
77. Apolipoprotein E and Amyloid-β-Independent Mechanisms in Alzheimer’s Disease
    Takahisa Kanekiyo, Guojun Bu · 2016 · Elsevier eBooks
78. Changing the treatment of heart failure with reduced ejection fraction: clinical use of sacubitril-valsartan combination.
    Edgardo Kaplinsky · 2016 · PubMed Central
79. Computational Approaches to Understand Cleavage Mechanism of Amyloid Beta (Aβ) Peptide
    Kailas Dashrath Sonawane, Maruti Jayram Dhanavade · 2017 · Neuromethods
80. The Molecular Physiopathogenesis of Islet Amyloidosis
    Diti Chatterjee Bhowmick, Sanghamitra Singh, Saurabh Trikha, Aleksandar M. Jeremic · 2017 · Handbook of experimental pharmacology
81. Enhanced amyloid-β generation by γ-secretase complex in DRM microdomains with reduced cholesterol levels
    Saori Hata, Anqi Hu, Yi Piao, Tadashi Nakaya, Hidenori Taru, Maho Morishima‐Kawashima, Shigeo Murayama, Masaki Nishimura, Toshiharu Suzuki · 2019 · Human Molecular Genetics
82. Selection of mutant µplasmin for amyloid-β cleavage in vivo
    Dongying Yang, Wei Zhu, Yingjie Wang, Fangmei Tan, Zhiping Ma, Jiali Gao, Xinli Lin · 2020 · Scientific Reports
83. A stress-enhanced model for discovery of disease-modifying gene: Ece1-suppresses the toxicity of α-synuclein A30P
    Alex Yen-Yu Chen, Tim Tully · 2018 · Neurobiology of Disease
84. The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme
    Claire A. Krasinski, Qiuchen Zheng, Valerie A. Ivancic, Donald E. Spratt, Noel D. Lazo · 2018 · ACS Chemical Neuroscience
85. Heterobifunctional proteomimetic polymers for targeted degradation of MYC and KRAS
    Max M. Wang, Mihai Ioan Truica, Brayley S. Gattis, Julia Oktawiec, Vinay Sagar, Ananya A. Basu, Paul A. Bertin, Xiaoyu Zhang, Sarki Abba Abdulkadir, Nathan C. Gianneschi · 2026 · Nature Communications
86. Overview of the Molecular Modalities and Signaling Pathways Intersecting with β-Amyloid and Tau Protein in Alzheimer’s Disease
    Ahmed M. Elshazly, Melanie M. Sinanian, Diaaeldin M. Elimam, Sherin Zakaria · 2023 · Neuroglia
87. Raw Inonotus obliquus polysaccharide counteracts Alzheimer’s disease in a transgenic mouse model by activating the ubiquitin-proteosome system
    Shumin Wang, Kaiye Dong, Ji Zhang, Chaochao Chen, Hongyan Shuai, Xin Yu · 2023 · Nutrition Research and Practice
88. Inhibition of amyloid beta oligomer accumulation by NU-9: A unifying mechanism for the treatment of neurodegenerative diseases
    Elizabeth Anne Johnson, Raghad Nowar, Kirsten L. Viola, Weijian Huang, Sihang Zhou, Maira Assunção Bicca, Wei Zhu, Daniel L. Kranz, William L. Klein, Richard B. Silverman · 2025 · Proceedings of the National Academy of Sciences
89. The growth rate of senile plaques is determined by the competition between the rate of deposition of free Aβ aggregates into plaques and the autocatalytic production of free Aβ aggregates
    Andrey V. Kuznetsov · 2024 · Journal of Theoretical Biology
90. Unraveling APOE4's Role in Alzheimer's Disease: Pathologies and Therapeutic Strategies
    Siddhant Tripathi, Yashika Sharma, Dileep Kumar · 2024 · Current Protein and Peptide Science
91. Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells
    Yuxin Chen, Chunyu Zhou, Mona Abdelhamid, Cha‐Gyun Jung, Makoto Michikawa · 2023 · The Journal of Biochemistry
92. Krüppel-like factor 9 alleviates Alzheimer’s disease via IDE-mediated Aβ degradation
    Yue-yao Feng, Jing-ran Hao, Yujie Zhang, Tong-tong Qiu, Meng-Lin Zhang, Wei Qiao, Jinjin Wu, Ping Qiu, Chao-fan Xu, Yinliang Zhang et al. · 2025 · Acta Pharmacologica Sinica
93. Bromelain prevents Alzheimer's disease progression by suppressing oxidative stress and upregulating apolipoprotein A1 in 5x familial Alzheimer's disease transgenic mice
    Julia Chu-Ning Hsu, Po-An Hu, Chia‐Hui Chen, Chia-Ju Lee, Hsuan-Yun Hu, Man‐Chen Hsu, Wen‐Hua Chen, Hsueh‐Te Lee, Tzong‐Shyuan Lee · 2025 · Journal of Agriculture and Food Research
94. Diabetes and Alzheimer’s Disease
    Shuko Takeda, Ryuichi Morishita · 2017 · Springer eBooks
95. CNTNAP2 Protein Is Degraded by the Ubiquitin–Proteasome System and the Macroautophagy-Lysosome Pathway
    Qing Hua Zhang, Keenan Sterling, Lu Xu, Mengen Xing, Fang Cai, Sheng Yuan Yu, Isabel Bestard‐Lorigados, Weihong Song · 2023 · Molecular Neurobiology
96. Sulodexide and Alzheimer’s Disease: A Preliminary Prospective Study
    J. Lasierra-Cirujeda, M. Pascual-Salcedo, M. Pascual-Salcedo · 2016 · World Journal of Cardiovascular Diseases
97. Neuronal aging potentiates beta-amyloid generation via amyloid precursor protein endocytosis
    Tatiana Burrinha, Ricardo A. Gomes, Ana Paula Terrasso, Cláudia Guimas Almeida · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
98. Lysosomal enzyme tripeptidyl peptidase 1 plays a role in degradation of beta amyloid fibrils
    Dana L. Cruz, Mukarram El-Banna, Amitabha Majumdar, David E. Sleat, Michelle Muldowney, Peter Lobel, Frederick R. Maxfield · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
99. Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease
    Carla Hartmann, Undine Haferkamp, Antje Appelt‐Menzel, Janica Barenberg, Andreas Brachner, Toni Ehrhard, Julia Silvia Feldhaus, Anna Gerhartl, Thomas Hollemann, Linda Anna Michelle Kulka et al. · 2026 · Fluids and Barriers of the CNS
100. Molecular Imaging of Cardiac Amyloidosis
     Sarah A. M. Cuddy, Rodney H. Falk, Sharmila Dorbala · 2018 · Current Cardiovascular Imaging Reports