Proteolytic Degradation of Amyloid -Protein

Cited by (369)

Items 301–369 of 369

1. Primate-specific 82-kDa choline acetyltransferase attenuates progression of Alzheimer’s disease-like pathology in the APPNL-G-F knock-in mouse model
   Hadir E. AlQot, Rebecca Jane Rylett · 2024 · Scientific Reports
2. Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer’s disease like pathology
   Ivan Arisi, Mara D’Onofrio, Rossella Brandi, Antonino Cattaneo, Paola Bertolazzi, Fabio Cumbo, Giovanni Felici, Concettina Guerra · 2015 · BMC Neuroscience
3. Mild blast wave exposure produces intensity-dependent changes in MMP2 expression patches in rat brains – Findings from different blast severities
   Takaki Inui, Michael E. Hoffer, Carey D. Balaban · 2021 · Brain Research
4. Predicting biological age using an accumulated neurotoxicity biomarker for amyloid beta oligomers
   Andrey V. Kuznetsov · 2026 · Mathematical Medicine and Biology A Journal of the IMA
5. Chlorin e6 and Amyloid-Targeting Peptide-Conjugated Superparamagnetic Iron Oxide Nanoparticles for Synchronous Amyloid Dual-Modal Imaging and Clearance in Alzheimer’s Therapy
   Chaoren Yan, Yuming Qi, Ruobing Zhao, Zhaohong Zhu, Zhaoxiong Yan, Chen Qian, Yixuan Wang, Yansong Li, Lianfeng Liu, Nan Zhang et al. · 2025 · ACS Applied Nano Materials
6. Functions of the basal lamina and ApoE in cerebral amyloid angiopathy
   A. Juan-Palencia, Yao Yao · 2025 · Fluids and Barriers of the CNS
7. Degradation of Amyloid-β Species by Multi-Copper Oxidases
   Jing Yang, Kathleen Renee Ran, Wenzhe Ma, Yanshi Chen, Yanxin Chen, Can Martin Zhang, Hui Ye, Ying Lu, Chongzhao Ran · 2024 · Journal of Alzheimer s Disease
8. Abnormal Expression of Proteolytic Stress‐Related Proteins and Protective Effect of Fibrinolytic Enzymes in Prion Diseases
   Yong-Chan Kim, Sae‐Young Won, Byung‐Hoon Jeong · 2025 · Transboundary and Emerging Diseases
9. Amyloid fil rouge from invertebrate up to human ageing: A focus on Alzheimer disease
   Magda de Eguileor, Annalisa Grimaldi, Laura Pulze, Francesco Acquati, Cristina Morsiani, Miriam Capri · 2022 · Mechanisms of Ageing and Development
10. A lysosomal surveillance response (LySR) that reduces proteotoxicity and extends healthspan
    Terytty Yang Li, Arwen W. Gao, Xiaoxu Li, Yasmine J. Liu, Rachel N. Arey, Kimberly Morales, Amélia Lalou, Qi Wang, Tanes Iamamura de Lima, Johan H. Auwerx · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
11. De novo design of metalloproteases for targeted amyloid-β cleavage
    Yannan Qu, Chentong Wang, Hongli Zhu, Yanjun Wang, Longxing Cao · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
12. Identification of Substrate-specific Allosteric Fingerprints in Matrix Metalloprotease-1 on Amyloid-beta Peptide Aggregates and Drug Screening With Single Molecule Insights
    Kamboj, Sumaer, Harms, Chase, Wright, Derek, Nash, Anthony, Klein-Seetharaman, Judith, Sarkar, Susanta K. · 2022
13. The Potential Use of Blood, Cerebrospinal Fluid, Saliva and Urine as Biological Samples for the Diagnosis of Alzheimer’s Disease
    Adnan Awn Algarni, Abdulhadi Ibrahim Hussain Bima, Ayman Zaky Elsamanoudy · 2020 · International Journal of Biochemistry Research & Review
14. Unlocking the therapeutic promise of miRNAs in promoting amyloid-β clearance for Alzheimer's disease
    Vajinder Kaur, Aditya Sunkaria · 2025 · Behavioural Brain Research
15. Utilizing fractional-order operator to Alzheimer’s disease dynamics
    Kottakkaran Sooppy Nisar, Muhammad Farman · 2026 · Scientific Reports
16. Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation
    W. Sambhariya, Catherine Bowes Rickman, P. A. d’Amore, G. Corradetti, G. S. Hageman, Gareth R. Howell, Olivia J. Marola, H. Phatnani, N. Philp, Debasish Sinha et al. · 2026 · Progress in retinal and eye research
17. Inhibition of NF-κB signaling pathway facilitates amyloid-β clearance by kallikrein-related peptidase 7
    Yuki Sudo, Chia-Jen Sung, Rie Nakayoshi, Honoka Kobayashi, Kazunori Kikuchi, Yung‐Wen Chiu, Sho Takatori, Yukiko Hori, Taisuke Tomita · 2026 · Molecular Neurodegeneration Advances
18. De novo design of metalloproteases for targeted amyloid-β cleavage
    Yannan Qu, Chentong Wang, Hongli Zhu, Yanjun Wang, Longxing Cao · 2026 · Vita
19. Futuristic aspect of nanocarriers on targeted delivery for dementia
    Shobha Kumari, Jayant Singh Bhardwaj, Sanskruti Santosh Kharavtekar, Deepika Grewal, Shreyasi Ghosh Ray, Abhay Bhardwaj, Sunil Kumar Dubey, Prashant Kesharwani, Taruna Katyal Arora, Rajeev Taliyan · 2022 · Elsevier eBooks
20. Aging and brain free cholesterol concentration on amyloid‐β peptide accumulation in guinea pigs
    K. Sandy Pang, Hao Peng, Betty P. Li, Binyu Wen, Keumhan Noh, Runyu Xia, Anja Toscan, Sylvia Serson, Paul E. Fraser, Rommel G. Tirona et al. · 2024 · Biopharmaceutics & Drug Disposition
21. The dynamic nature of amyloid-beta protein aggregation and its association to Alzheimer’s disease
    Sílvia Vilaprinyó-Pascual · 2015 · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
22. Investigating Amyloid β toxicity in Drosophila melanogaster
    M. Jonson · 2017 · Linköping studies in science and technology. Dissertations
23. Amyloid-β Derived from the Brain of the Alzheimer’s Disease Transgenic Mouse Is Resistant to Proteolytic Digestion Due to Its Conformation
    Baian Chen, Jing Zhang, Shubo Wang, Wen Wang, Zitong Yao, Quan Sun, Yi Wu, Jing Nan Lu · 2017 · Journal of Molecular Neuroscience
24. Targeting Astrocytes With Viral Gene Therapy for Alzheimer’s Disease
    Zachary P. Rosenthal, Andrew W. Kraft, Leah R. Czerniewski, Jin‐Moo Lee · 2018 · Elsevier eBooks
25. El polimorfismo humano ARG72PRO de Tp53 condiciona a la susceptibilidad neuronal a B-Amiloide
    Rebeca Lapresa Ruiz de Gauna · 2016
26. The Influence of Proteins Surface on the Ordering of Surrounded Water
    Mateusz Banach, Leszek Konieczny, Irena Roterman · 2019 · IntechOpen eBooks
27. Genetic manipulation of CNS cholesterol metabolism and its effects on cerebral β-amyloidosis
    Jan Winchenbach · 2019
28. The relation between human biomarkers and oxidative stress in Alzheimer’s disease, novel in vivo experimental modelling possibilities
    Zita Galik-Olah · 2018
29. Amyloid beta: from pre-analytical factors to disease mechanisms
    Jamie Toombs · 2019 · UCL Discovery (University College London)
30. Genetic and functional studies of genes involved in the pathogenesis of Alzheimer's disease
    Teemu Natunen · 2014 · UEF eRepo (University of Eastern Finland)
31. APOE ε4 allele advances the age-dependent decline of amyloid β clearance in the human cortex
    Atsushi Saito, Yusuke Kageyama, Olga Pletniková, Gay L. Rudow, Yang An, Yumi Irie, Akiko Kita, Kunio Miki, Ling Li, Pamela E. Southall et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
32. Faculty Opinions recommendation of Neuroinflammation in Alzheimer's disease.
    Daniela Perani · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
33. Degradation of amyloid beta species by multi-copper oxidases
    Jing Yang, Kathleen Renee Ran, Wenzhe Ma, Lucy L Chen, Cindy Si Chen, Can Martin Zhang, Hui Ye, Ying Lu, Chongzhao Ran · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
34. Deep learning-based cell profiling based on neuronal morphology
    Qiang Liu, Francesca J. Nicholls, Helen A. Rowland, Adrià Dangla-Valls, Shuhan Li, Yi Zhang, Piotr Kalinowski, Elena M. Ribé, Jamie L. Ifkovits, Sanjay Kumar et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
35. Metabolism of Aβ: Catabolic and glymphatic systems
    Takaomi C. Saido · 2024 · Elsevier eBooks
36. Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity
    Jordan M Mancl, Wenguang G. Liang, Nicholas L Bayhi, Hui Alex Wei, William C. Budell, Joshua H. Mendez, Tobin R. Sosnick, Bridget O Carragher, Clinton S. Potter, Wei‐Jen Tang · 2026 · eLife
37. Heterobifunctional proteomimetic polymers for targeted protein degradation
    Max Mu Wang, Mihai Ioan Truica, Brayley S. Gattis, Julia Oktawiec, Vinay Sagar, Ananya A. Basu, Paul A. Bertin, Xiaoyu Zhang, Sarki Abba Abdulkadir, Nathan C. Gianneschi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
38. Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity
    Jordan M Mancl, Wenguang G. Liang, Nicholas L Bayhi, Hui Alex Wei, Bridget O Carragher, Clinton S. Potter, Wei‐Jen Tang · 2025 · eLife
39. Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity
    Jordan M Mancl, Wenguang G. Liang, Nicholas L Bayhi, Hui Alex Wei, William C. Budell, Joshua H. Mendez, Tobin R. Sosnick, Bridget Carragher, Clinton S Potter, Wei-Jen Tang · 2025 · eLife
40. Role and relation of cell death in Alzheimer’s disease
    Duc Anh Hoang, Duc Anh Le, Thi My Hanh Do, Van Thai Than · 2025 · Progress in molecular biology and translational science
41. Increased Concentration of Anti-Egg Albumin Antibodies in Cerebrospinal Fluid and Serum of Patients with Alzheimer’s Disease—Discussion on Human Serpins’ Similarity and Probable Involvement in the Disease Mechanism
    Dionysia Amanatidou, Magda Tsolaki, Vasileios Fouskas, Ioannis Gavriilidis, Maria Myriouni, Anna Anastasiou, Efthimia Papageorgiou, Diona Porfyriadou, Zoi Parcharidi, Eleftheria Papasavva et al. · 2025 · Biomolecules
42. Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity
    Jordan M Mancl, Wenguang G. Liang, Nicholas L Bayhi, Hui Alex Wei, William C. Budell, Joshua H. Mendez, Tobin R. Sosnick, Bridget O Carragher, Clinton S. Potter, Wei‐Jen Tang · 2025 · eLife
43. Molecular chaperones as therapeutic gatekeepers in Alzheimer’s disease: Intersections with Tau aggregation, amyloid burden, and neuroinflammation
    Yukti, Anushka Sharma, Sarthak Dhar, Rupal Ojha, Vijay Kumar Prajapati · 2025 · Advances in protein chemistry and structural biology
44. Additional file 1 of Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis
    Heather M. Terron, Sagar J. Parikh, Abdul-Hay, Samer O., Tomoko Sahara, Dongcheul Kang, Dennis W. Dickson, Paul Säftig, LaFerla, Frank M., Shelley D. Lane, Malcolm A. Leissring · 2024 · Figshare
45. Additional file 2 of Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis
    Heather M. Terron, Sagar J. Parikh, Abdul-Hay, Samer O., Tomoko Sahara, Dongcheul Kang, Dennis W. Dickson, Paul Säftig, LaFerla, Frank M., Shelley D. Lane, Malcolm A. Leissring · 2024 · Figshare
46. Preclinical advances in antibodies against N‐terminal Aβ4‐x species for Alzheimer's disease and cerebral amyloid angiopathy
    María Luisa del Valle, Donatello Arienzo · 2026 · Ibrain
47. Etude de l'interaction du TIMP-1 avec ses récepteurs
    Laurie Verzeaux · 2015
48. Oxidation of the amyloid-beta peptide and consequences on the etiology of Alzheimer's disease
    Clémence Cheignon · 2016 · theses.fr (ABES)
49. Conception de dérivés 2-aryl-benzothiazoles pour la reconnaissance d'agrégats du peptide amyloïde-β par diverses approches physico-chimiques
    Alexandre Pocinho · 2018 · theses.fr (ABES)
50. Stratégie de prévention de la maladie d'Alzheimer : Étude du rôle de la vitamine A
    Essi F. Biyong · 2019 · theses.fr (ABES)
51. MT5-MMP promotes neuroinflammation, pathogenic processing of amyloid precursor protein and synaptic dysfunction at early stages in an Alzheimer's disease model
    Dominika Piłat · 2021 · theses.fr (ABES)
52. 3S-HS et HS3ST2 dans les macrophages humains : implication dans le diagnostic de la maladie d'Alzheimer
    Oulfa Ben Abdelouahab · 2021 · theses.fr (ABES)
53. Influences biochimiques, anatomiques et cognitives de la troncation exopeptidasique N-terminale du peptide Aβ
    Audrey Valverde · 2020 · theses.fr (ABES)
54. Contribution à l'étude des facteurs de risque pour la maladie d'Alzheimer : analyse de candidats identifiés par étude d'association pangénomique ou GWAS
    Charlotte Bauer · 2023 · theses.fr (ABES)
55. Design and synthesis of trisubstituted 1,2,4-triazoles : structural exploration in the inhibition of GSK-3β for the treatment of Alzheimer’s disease
    Thiago M. Pereira · 2024 · theses.fr (ABES)
56. Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity
    Jordan M Mancl, Wenguang G. Liang, Nicholas L Bayhi, Hui Alex Wei, William C. Budell, Joshua H. Mendez, Tobin R. Sosnick, Bridget O Carragher, Clinton S. Potter, Wei‐Jen Tang · 2026 · eLife
57. Secretory form of viral protease NIa ameliorates amyloid-β pathology and cognitive deficits in a mouse model of Alzheimer’s disease
    Euy Jun Park, Bo-Ram Mun, Sung Yoon Kim, Muthukumar Elangovan, Sung Bin Kim, Won-Seok Choi, Woo Jin Park · 2026 · Frontiers in Aging Neuroscience
58. A perivascular perspective on the immune impacts in cerebral amyloid angiopathy
    Beth Eyre, Stephanie K. Bonney · 2026 · Journal of Cerebral Blood Flow & Metabolism
59. Second Section: A single domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF
    Liliana Napolitano · 2026 · Firenze University Press eBooks
60. References
    Liliana Napolitano · 2026 · Firenze University Press eBooks
61. Discussion
    Liliana Napolitano · 2026 · Firenze University Press eBooks
62. Third Section: Design of a dimeric-nanobody specific for Aβ42 oligomers: the Dimeric-DesAb-O
    Liliana Napolitano · 2026 · Firenze University Press eBooks
63. A multidisciplinary approach for the early diagnosis of Alzheimer’s disease and potential therapeutic applications
    Liliana Napolitano · 2026 · Firenze University Press eBooks
64. Material and Methods
    Liliana Napolitano · 2026 · Firenze University Press eBooks
65. First Section: Putative CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
    Liliana Napolitano · 2026 · Firenze University Press eBooks
66. Introduction
    Liliana Napolitano · 2026 · Firenze University Press eBooks
67. Conclusion and Future Perspectives
    Liliana Napolitano · 2026 · Firenze University Press eBooks
68. Glymphatic dysfunction in Alzheimer's disease: a systematic review and meta-analysis of the DTI-ALPS index as an imaging biomarker
    Yutong Wu, Chen Zhang, Jiayi Yan, Lan Lin, Yuan Tian, Zhenrong Fu, Xiaojun Sun · 2026 · Frontiers in Aging Neuroscience
69. Analytical performance of a delayed-centrifugation blood collection tube for remote blood biomarker assessment
    You‐Rim Lee, Xuemei Zeng, Marissa F. Farinas, Brian J. Lopresti, Rima F. Habte, Kristine A. Wilckens, Thomas K. Karikari · 2026 · medRxiv