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Cited by 801

The DOI matches its Crossref record; 164 of the 164 references it cites were found in a registry or an index.

Nucleotide Excision Repair in Eukaryotes

Open access
Scharer, O. D.·2013·Cold Spring Harbor Perspectives in Biology

Abstract

Nucleotide excision repair (NER) is the main pathway used by mammals to remove bulky DNA lesions such as those formed by UV light, environmental mutagens, and some cancer chemotherapeutic adducts from DNA. Deficiencies in NER are associated with the extremely skin cancer-prone inherited disorder xeroderma pigmentosum. Although the core NER reaction and the factors that execute it have been known for some years, recent studies have led to a much more detailed understanding of the NER mechanism, how NER operates in the context of chromatin, and how it is connected to other cellular processes such as DNA damage signaling and transcription. This review emphasizes biochemical, structural, cell biological, and genetic studies since 2005 that have shed light on many aspects of the NER pathway.

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Metadata

Authors
Scharer, O. D.
Venue
Cold Spring Harbor Perspectives in Biology
Published
2013-10-01
Volume
5
Issue
10
Pages
a012609-a012609
ISSN
1943-0264 (ISSN-L)
OpenAlex
W2097124161
Cited by
801
References
164
Type
posted content
Language
en
Open access
green

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CoChat. (2026). Citation check: Nucleotide Excision Repair in Eukaryotes. https://app.cochat.ai/papers/10.1101/cshperspect.a012609
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Scharer, O. D. (2013). Nucleotide Excision Repair in Eukaryotes. Cold Spring Harbor Perspectives in Biology. https://doi.org/10.1101/cshperspect.a012609

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