pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes

Antibodies, a laboratory manual

(1989) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(89)90130-3 · Cited by 12,318

Cancer Cell Cycles

Sherr, C. J. (1996) · Science · doi:10.1126/science.274.5293.1672 · Cited by 5,379

The retinoblastoma protein and cell cycle control

Weinberg, R. A. (1995) · Cell · doi:10.1016/0092-8674(95)90385-2 · Cited by 4,862

Effects of an Rb mutation in the mouse

Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A., & Weinberg, R. A. (1992) · Nature · doi:10.1038/359295a0 · Cited by 1,755

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

Lee, E. Y.-H. P., Chang, C.-Y., Hu, N., Wang, Y.-C. J., Lai, C., Herrup, K., Lee, W., & Bradley, A. (1992) · Nature · doi:10.1038/359288a0 · Cited by 1,264

Requirement for a functional Rb-1 gene in murine development

Clarke, A. R., Maandag, E. R., van ROON, M. A., van der Lugt, N. M. T., van der Valk, M., Hooper, M., Berns, A. J. M., & Rielef, H. T. (1992) · Nature · doi:10.1038/359328a0 · Cited by 1,006

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

Johnson, D. G., Schwarz, J. K., Cress, W. D., & Nevins, J. R. (1993) · Nature · doi:10.1038/365349a0 · Cited by 943

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G 1 /S-Regulatory Genes

DeGregori, J. V., Kowalik, T. F., & Nevins, J. R. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.8.4215 · Cited by 918

Cyclin-Dependent Regulation of G 1 in Mammalian Fibroblasts

Ohtsubo, M., & Roberts, J. M. (1993) · Science · doi:10.1126/science.8384376 · Cited by 767

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

Resnitzky, D., Gossen, M., Bujard, H., & Reed, S. I. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.3.1669 · Cited by 664

Human stanniocalcin-2 exhibits potent growth-suppressive properties in transgenic mice independently of growth hormone and IGFs

Gagliardi, A. D., Kuo, E. Y. W., Raulic, S., Wagner, G. F., & DiMattia, G. E. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00268.2004 · Cited by 126

Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis

Greasley, P. J. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.2.446 · Cited by 126

The central role of CDE/CHR promoter elements in the regulation of cell cycle‐dependent gene transcription

Müller, G. A., & Engeland, K. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07508.x · Cited by 123

Regulation of BRCA1 Expression by the Rb-E2F Pathway

Wang, A., Schneider‐Broussard, R., Kumar, A. P., MacLeod, M. C., & Johnson, D. G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.6.4532 · Cited by 122

G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

Connell‐Crowley, L., Elledge, S. J., & Harper, J. W. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70021-1 · Cited by 122

Regulation of E2F: a family of transcription factors involved in proliferation control

Black, A. R., & Azizkhan‐Clifford, J. (1999) · Gene · doi:10.1016/s0378-1119(99)00305-4 · Cited by 121

E2F4 loss suppresses tumorigenesis in Rb mutant mice

Lee, E. Y., Cam, H., Ziebold, U., Rayman, J. B., Lees, J. A., & Dynlacht, B. D. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00207-6 · Cited by 120

Transformation by v-Myb

Lipsick, J. S., & Wang, D.-M. (1999) · Oncogene · doi:10.1038/sj.onc.1202745 · Cited by 117

Cloning and Functional Studies of a Novel Gene Aberrantly Expressed in RB-Deficient Embryos

Yuan, S. F., Cox, L. A., Dasika, G. K., & Lee, E. Y.-H. P. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9141 · Cited by 119

Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation

David, G., Grandinetti, K. B., Finnerty, P. M., Simpson, N. E., Chu, G. C., & DePinho, R. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710285105 · Cited by 122

Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells

Balciunaite, E., Spektor, A., Lents, N. H., Cam, H., te Riele, H., Scime, A., Rudnicki, M. A., Young, R., & Dynlacht, B. D. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.18.8166-8178.2005 · Cited by 116

Cumulative Effect of Phosphorylation of pRB on Regulation of E2F Activity

Brown, V. D., Phillips, R. A., & Gallie, B. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3246 · Cited by 116

Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control

Classon, M., Salama, S. R., Gorka, C., Mulloy, R., Falter‐Braun, P., & Harlow, E. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.190343497 · Cited by 115

The mitogen‐activated protein (MAP) kinase ERK induces tRNA synthesis by phosphorylating TFIIIB

Felton-Edkins, Z. A., Fairley, J. A., Graham, E. L., Johnston, I. M., White, R. J., & Scott, P. H. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg240 · Cited by 121

Cell cycle regulation of folate‐mediated one‐carbon metabolism

Lan, X., Field, M. S., & Stover, P. J. (2018) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1426 · Cited by 113

Mécanismes moléculaires contrôlant le cycle cellulaire : aspects fondamentaux et implications en cancérologie

Viallard, J.-F., Lacombe, F., Belloc, F., Pellegrin, J., & Reiffers, J. J. (2001) · Cancer/Radiothérapie · doi:10.1016/s1278-3218(01)00087-7 · Cited by 123

Direct Transactivation of the Anti-apoptotic Gene Apolipoprotein J (Clusterin) by B-MYB

Cervellera, M. N., Raschellà, G., Santilli, G., Tanno, B., Ventura, A., Mancini, C., Sevignani, C., Calabretta, B., & Sala, A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002055200 · Cited by 112

DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation

Uxa, S., Bernhart, S. H., Mages, C. F., Fischer, M., Kohler, R., Hoffmann, S., Stadler, P. F., Engeland, K., & Müller, G. A. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz635 · Cited by 121

The Mammalian Cell Cycle: An Overview

Harper, J. V., & Brooks, G. (2004) · Humana Press eBooks · doi:10.1385/1-59259-857-9:113 · Cited by 112

Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex

Pilkinton, M. A., Sandoval, R., & Colamonici, O. R. (2007) · Oncogene · doi:10.1038/sj.onc.1210562 · Cited by 115

p130/E2F4 Binds to and Represses the cdc2 Promoter in Response to p53

Taylor, W. R., Schönthal, A. H., Galante, J., & Stark, G. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005101200 · Cited by 110

C/EBPα Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice

Timchenko, N. A., Wilde, M., & Darlington, G. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.4.2936 · Cited by 106

New roles for the RB tumor suppressor protein

Liu, H., Dibling, B. C., Spike, B. T., Dirlam, A., & Macleod, K. F. (2003) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2003.11.005 · Cited by 107

Development of the Ocular Lens

(2004) · Cambridge University Press eBooks · doi:10.1017/cbo9780511529825 · Cited by 105

Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer.

Michalides, R. J. A. M. (1999) · Journal of Clinical Pathology · doi:10.1136/jcp.52.8.555 · Cited by 104

Phosphorylation‐dependent and ‐independent functions of p130 cooperate to evoke a sustained G1 block

Hansen, K. H., Farkas, T., Lukas, J., Holm, K., Rönnstrand, L., & Bartek, J. (2001) · The EMBO Journal · doi:10.1093/emboj/20.3.422 · Cited by 104

S-Phase entry upon ectopic expression of G1 cyclin-dependent kinases in the absence of retinoblastoma protein phosphorylation

Leng, X., Connell‐Crowley, L., Goodrich, D. W., & Harper, J. W. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00301-0 · Cited by 105

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

Nolan-Stevaux, O., Dimova, D., Frolov, M. V., Taylor‐Harding, B., Morris, E., & Dyson, N. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf501 · Cited by 106

Cell cycle regulation by the B-Myb transcription factor

Joaquin, M., & Watson, R. J. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-3037-4 · Cited by 102

S Phase-specific Transcription of the Mouse Ribonucleotide Reductase R2 Gene Requires Both a Proximal Repressive E2F-binding Site and an Upstream Promoter Activating Region

Chabes, A. L., Björklund, S., & Thelander, L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312482200 · Cited by 102

Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins

Samuelson, A. V., & Lowe, S. W. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.22.12094 · Cited by 102

Liver-Specific pRB Loss Results in Ectopic Cell Cycle Entry and Aberrant Ploidy

Mayhew, C. N., Bosco, E. E., Fox, S. R., Okaya, T., Tarapore, P., Schwemberger, S. J., Babcock, G. F., Lentsch, A. B., Fukasawa, K., & Knudsen, E. S. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-4221 · Cited by 101

Burkitt’s lymphoma: new insights into molecular pathogenesis

Bellan, C., Lazzi, S., Falco, G. D., Nyongo, A., Giordano, A., & Leoncini, L. (2003) · Journal of Clinical Pathology · doi:10.1136/jcp.56.3.188 · Cited by 96

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2

Jackson, M. W., Agarwal, M. K., Yang, J., Bruss, P., Uchiumi, T., Agarwal, M. L., Stark, G. R., & Taylor (2005) · Journal of Cell Science · doi:10.1242/jcs.02307 · Cited by 92

Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex

Cam, L. L., Polanowska, J., Fabbrizio, E., Olivier, M., Philips, A., Eaton, E. N., Classon, M., Geng, Y., & Sardet, C. (1999) · The EMBO Journal · doi:10.1093/emboj/18.7.1878 · Cited by 91

Serum-Induced Expression of the cdc25A Gene by Relief of E2F-Mediated Repression

Chen, X., & Prywes, R. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.7.4695 · Cited by 90

Deregulated E2f Transcriptional Activity in Autonomously Growing Melanoma Cells

Halaban, R., Cheng, E., Smicun, Y., & Germino, J. F. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.6.1005 · Cited by 87

Regulation of transcription and chromatin structure by pRB: Here, there and everywhere

Talluri, S., & Dick, F. A. (2012) · Cell Cycle · doi:10.4161/cc.21263 · Cited by 91

Retinoblastoma Tumor Suppressor Targets dNTP Metabolism to Regulate DNA Replication

Angus, S. P., Wheeler, L. J., Ranmal, S. A., Zhang, X., Markey, M. P., Mathews, C. K., & Knudsen, E. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205911200 · Cited by 91

Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein

Kelly, B. L., Wolfe, K. G., & Roberts, J. M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2535 · Cited by 87

G1 Cyclin/Cyclin-dependent Kinase-coordinated Phosphorylation of Endogenous Pocket Proteins Differentially Regulates Their Interactions with E2F4 and E2F1 and Gene Expression

Calbó, J., Parreño, M., Sotillo, E., Yong, T., Mazo, A., Garriga, J., & Graña, X. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209181200 · Cited by 87

Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylationPreprint

Nicolay, B., Danielian, P. S., Kottakis, F., Lapek, J. D., Sanidas, I., Miles, W. O., Dehnad, M., Tschöp, K., Gierut, J. J., Manning, A. L., et al. (2015) · Genes & Development · doi:10.1101/gad.264127.115 · Cited by 84

Reversal of Growth Suppression by p107 via Direct Phosphorylation by Cyclin D1/Cyclin-Dependent Kinase 4

Leng, X., Noble, M. E. M., Adams, P. D., Qin, J., & Harper, J. W. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.7.2242-2254.2002 · Cited by 85

HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling

Kim, Y.-R., Oh, K. J., Park, R., Xuân, N. T., Kang, T.-W., Kwon, D., Choi, C., Kim, M. S., Kim, K. K., Ahn, K. Y., et al. (2010) · Molecular Cancer · doi:10.1186/1476-4598-9-124 · Cited by 83

A role for cadherins in cellular signaling and differentiation

Knudsen, K. A., Frankowski, C., Johnson, K. R., & Wheelock, M. J. (1998) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(1998)72:30/31+ · Cited by 88

The human cytomegalovirus immediate early 2 protein dissociates cellular DNA synthesis from cyclin‐dependent kinase activation

Wiebusch, L., & Hagemeier, C. (2001) · The EMBO Journal · doi:10.1093/emboj/20.5.1086 · Cited by 81

E2F1 Expression is Related with the Poor Survival of Lymph Node-positive Breast Cancer Patients Treated with Fluorouracil, Doxorubicin and Cyclophosphamide

Han, S., Park, K., Bae, B., Kim, K. H., Kim, H.-J., Kim, Y., & Kim, H.-Y. (2003) · Breast Cancer Research and Treatment · doi:10.1023/b:brea.0000003843.53726.63 · Cited by 80

Identification of E2F-3B, an alternative form of E2F-3 lacking a conserved N-terminal region

He, Y., Armanious, M. K., Thomas, M. J., & Cress, W. D. (2000) · Oncogene · doi:10.1038/sj.onc.1203682 · Cited by 79

Network calisthenics

Wong, J. V., Dong, P., Nevins, J. R., Mathey-Prévôt, B., & You, L. (2011) · Cell Cycle · doi:10.4161/cc.10.18.17350 · Cited by 83

Retinoblastoma Protein Disrupts Interactions Required for RNA Polymerase III Transcription

Sutcliffe, J. E., Brown, T. R. P., Allison, S. J., Scott, P., & White, R. J. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.24.9192-9202.2000 · Cited by 77

RBR3, a member of the retinoblastoma-related family from maize, is regulated by the RBR1/E2F pathway

Sabelli, P. A., Dante, R. A., Leiva-Neto, J. T., Jung, R., Gordon-Kamm, W. J., & Larkins, B. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506160102 · Cited by 76

Developmental defects and tumor predisposition in Rb mutant mice

Vooijs, M., & Berns, A. J. M. (1999) · Oncogene · doi:10.1038/sj.onc.1202999 · Cited by 77

RB, p130 and p107 differentially repress G1/S and G2/M genes after p53 activation

Schade, A. E., Fischer, M., & DeCaprio, J. A. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz961 · Cited by 74

CDK8 regulates E2F1 transcriptional activity through S375 phosphorylation

Zhao, J., Ramos, R., & Demma, M. J. (2012) · Oncogene · doi:10.1038/onc.2012.364 · Cited by 83

Tumour suppressor retinoblastoma protein Rb: A transcriptional regulator

Zhu, L. (2005) · European Journal of Cancer · doi:10.1016/j.ejca.2005.08.009 · Cited by 77

Myb and Oncogenesis

Ganter, B., & Lipsick, J. S. (1999) · Advances in cancer research · doi:10.1016/s0065-230x(08)60773-3 · Cited by 75

Neural Precursor Cells Differentiating in the Absence of Rb Exhibit Delayed Terminal Mitosis and Deregulated E2F 1 and 3 Activity

Callaghan, D. A., Dong, L., Callaghan, S. M., Hou, Y. X., Dagnino, L., & Slack, R. S. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9162 · Cited by 74

Activation of Rb and decline in androgen receptor protein precede retinoic acid-induced apoptosis in androgen-dependent LNCaP cells and their androgen-independent derivative

Gao, M., Ossowski, L., & Ferrari, A. C. (1999) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199906)179:3 · Cited by 86

Growth Suppression by an E2F-Binding-Defective Retinoblastoma Protein (RB): Contribution from the RB C Pocket

Whitaker, L. L., Su, H., Rajasekaran, B., Knudsen, E. S., & Wang, J. Y. J. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.7.4032 · Cited by 74

Cyclin A Is a Functional Target of Retinoblastoma Tumor Suppressor Protein-mediated Cell Cycle Arrest

Knudsen, K. E., Fribourg, A. F., Strobeck, M. W., Blanchard, J., & Knudsen, E. S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.39.27632 · Cited by 74

Regulation of Differentiation by HBP1, a Target of the Retinoblastoma Protein

Shih, H. H., Tevosian, S. G., & Yee, A. S. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.8.4732 · Cited by 73

Overlapping Functions of the pRb Family in the Regulation of rRNA Synthesis

Ciarmatori, S., Scott, P., Sutcliffe, J. E., McLees, A., Alzuherri, H. M., Dannenberg, J., Riele, H. T., Grummt, I., Voit, R., & White, R. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5806-5814.2001 · Cited by 74

Distinct gene expression phenotypes of cells lacking Rb and Rb family members.

Black, E. P., Huang, E. S., Dressman, H. K., Rempel, R. E., Laakso, N., Asa, S. L., Ishida, S., West, M., & Nevins, J. R. (2003) · PubMed · Cited by 73

Expression of cyclins E1 and E2 during mouse development and in neoplasia

Geng, Y., Yu, Q., Whoriskey, W. J., Dick, F. A., Tsai, K. Y., Ford, H. L., Biswas, D. K., Pardee, A. B., Amati, B. B., Jacks, T., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231487798 · Cited by 72

Distinct Phosphorylation Events Regulate p130- and p107-mediated Repression of E2F-4

Farkas, T., Hansen, K. H., Holm, K., Lukas, J., & Bártek, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200381200 · Cited by 72

p130 Is Dispensable in Peripheral T Lymphocytes: Evidence for Functional Compensation by p107 and pRB

Mulligan, G., Wong, J., & Jacks, T. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.1.206 · Cited by 72

Regulation of RNA polymerase III transcription during hypertrophic growth

Goodfellow, S. J., Innes, F., Derblay, L. E., MacLellan, W. R., Scott, P., & White, R. J. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601040 · Cited by 71

Drosophila myb is required for the G2/M transition and maintenance of diploidyPreprint

Katzen, A. L., Jackson, J., Harmon, B., Fung, S.-M., Ramsay, G. M., & Bishop, J. M. (1998) · Genes & Development · doi:10.1101/gad.12.6.831 · Cited by 71

E2F2 represses cell cycle regulators to maintain quiescence

Infante, A., Laresgoiti, U., Fernández‐Rueda, J., Fullaondo, A., Galán, J., Díaz‐Uriarte, R., Malumbres, M., Field, S. J., & Zubiaga, A. M. (2008) · Cell Cycle · doi:10.4161/cc.7.24.7379 · Cited by 74

Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter

Araki, K., Nakajima, Y., Eto, K., & Ikeda, M. (2003) · Oncogene · doi:10.1038/sj.onc.1206840 · Cited by 69

pRb and E2f-1 in mouse development and tumorigenesis

Macleod, K. F. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80005-7 · Cited by 70

Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation

Martinez, L. A., Chen, Y., Fischer, S. M., & Conti, C. J. (1999) · Oncogene · doi:10.1038/sj.onc.1202300 · Cited by 69

Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines

Burger, H., Nooter, K., Boersma, A. W. M., van Wingerden, K. E., Looijenga, L. H. J., Jochemsen, A. G., & Stoter, G. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990517)81:4 · Cited by 89

Murine bilateral retinoblastoma exhibiting rapid‐onset, metastatic progression and N‐myc gene amplification

MacPherson, D. P., Conkrite, K. L., Tam, M., Mukai, S., Mu, D., & Jacks, T. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601515 · Cited by 68

Lin9, a Subunit of the Mammalian DREAM Complex, Is Essential for Embryonic Development, for Survival of Adult Mice, and for Tumor Suppression

Reichert, N., Wurster, S., Ulrich, T., Schmitt, K., Hauser, S., Probst, L., Götz, R., Ceteci, F., Moll, R., Rapp, U. R., et al. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00028-10 · Cited by 68

Regulation of RNA Polymerase III Transcription during Cell Cycle Entry

Scott, P., Cairns, C. A., Sutcliffe, J. E., Alzuherri, H. M., McLees, A., Winter, A. G., & White, R. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005417200 · Cited by 71

Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability

Manak, J. R., Mitiku, N., & Lipsick, J. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122231599 · Cited by 68

Dual Cyclin-Binding Domains Are Required for p107 To Function as a Kinase Inhibitor

Castaño, E., Kleyner, Y., & Dynlacht, B. D. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.9.5380 · Cited by 67

Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation

Sangwan, M. L., McCurdy, S. R., Livne‐Bar, I., Ahmad, M. A. E.-R., Wrana, J. L., Chen, D., & Bremner, R. (2012) · Oncogene · doi:10.1038/onc.2011.654 · Cited by 68

E2F4 Actively Promotes the Initiation and Maintenance of Nerve Growth Factor-Induced Cell Differentiation

Persengiev, S. P., Kondova, I. I., & Kilpatrick, D. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6048 · Cited by 67

Tumor suppressor p53 promotes ferroptosis in oxidative stress conditions independent of modulation of ferroptosis by p21, CDKs, RB, and E2F

Kuganesan, N., Dlamini, S., Tillekeratne, L. M. V., & Taylor, W. R. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101365 · Cited by 71

Nucleocytoplasmic Shuttling of p130/RBL2: Novel Regulatory Mechanism

Chestukhin, A., Litovchick, L., Rudich, K., & DeCaprio, J. A. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.2.453-468.2002 · Cited by 66

RNA Polymerase III Transcription Factor IIIB Is a Target for Repression by Pocket Proteins p107 and p130

Sutcliffe, J. E., Cairns, C. A., McLees, A., Allison, S. J., Tosh, K., & White, R. J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4255 · Cited by 66

An RNA sequencing transcriptome analysis of the high-temperature stressed tall fescue reveals novel insights into plant thermotolerance

Hu, T., Sun, X., Zhang, X., Nevo, E., & Fu, J. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-1147 · Cited by 65

Regulation of RNA Polymerase III Transcription by Maf1 in Mammalian Cells

Goodfellow, S. J., Graham, E. L., Kantidakis, T., Marshall, L., Coppins, B. A., Oficjalska-Pham, D., Gérard, M., Lefebvre, O., & White, R. J. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.02.060 · Cited by 65

Three Regions of the pRB Pocket Domain Affect Its Inactivation by Human Papillomavirus E7 Proteins

Dick, F. A., & Dyson, N. J. (2002) · Journal of Virology · doi:10.1128/jvi.76.12.6224-6234.2002 · Cited by 65

Who is the boss in the retinoblastoma family? The point of view of Rb2/p130, the little brother.

Paggi, M. G., & Giordano, A. (2001) · PubMed · Cited by 65

Cooperation of E2F-p130 and Sp1-pRb Complexes in Repression of the Chinese Hamster dhfr Gene

Chang, Y., Illenye, S., & Heintz, N. H. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1121-1131.2001 · Cited by 64

Chapter 9 Regulation of Human Dihydrofolate Reductase Activity and Expression

Abali, E. E., Skacel, N. E., Çelikkaya, H., & Hsieh, Y. (2008) · Vitamins and hormones · doi:10.1016/s0083-6729(08)00409-3 · Cited by 63

Apoptosis Signal-regulating Kinase 1 Is a Direct Target of E2F1 and Contributes to Histone Deacetylase Inhibitorinduced Apoptosis through Positive Feedback Regulation of E2F1 Apoptotic Activity

Tan, J. Y., Zhuang, L., Jiang, X., Yang, K., Karuturi, K. M., & Yu, Q. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512719200 · Cited by 63

Retinoblastoma Protein Transcriptional Repression through Histone Deacetylation of a Single Nucleosome

Morrison, A. J., Sardet, C., & Herrera, R. E. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.3.856-865.2002 · Cited by 63

Interweaving the Cell Cycle Machinery with Cell Differentiation

Miller, J. P., Yeh, N., Vidal, A., & Koff, A. (2007) · Cell Cycle · doi:10.4161/cc.6.23.5042 · Cited by 62

The retinoblastoma gene is involved in multiple aspects of stem cell biology

Galderisi, U., Cipollaro, M., & Giordano, A. (2006) · Oncogene · doi:10.1038/sj.onc.1209736 · Cited by 62

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

Alessio, N., Bohn, W., Rauchberger, V., Rizzolio, F., Cipollaro, M., Rosemann, M., Irmler, M., Beckers, J., Giordano, A., & Galderisi, U. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1224-x · Cited by 61

Controlling cell proliferation in differentiating tissues: genetic analysis of negative regulators of G1→S-phase progression

Zavitz, K. H., & Zipursky, S. L. (1997) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(97)80077-4 · Cited by 60

Cyclin E1 Is Amplified and Overexpressed in Osteosarcoma

Lockwood, W. W., Stack, D., Morris, T., Grehan, D., O’Keane, C., Stewart, G. L., Cumiskey, J., Lam, W. L., Squire, J. A., Thomas, D. M., et al. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2010.11.020 · Cited by 59

Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel−/− B cells

Cheng, S., Hsia, C. Y., Leone, G. W., & Liou, H. (2003) · Oncogene · doi:10.1038/sj.onc.1206917 · Cited by 58

Paradigms of Growth Control: Relation to Cdk Activation

Olashaw, N., & Pledger, W. J. (2002) · Science Signaling · doi:10.1126/stke.2002.134.re7 · Cited by 59

Cell cycle regulation in the developing lens

Griep, A. E. (2006) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2006.10.004 · Cited by 58

Expression of RB2/p130 tumor-suppressor gene in AIDS-related non-Hodgkin's lymphomas: Implications for disease pathogenesis

Lazzi, S., Bellan, C., Falco, G. D., Cinti, C., Ferrari, F., Nyong'o, A. O., Claudio, P. P., Tosi, G. M., Vatti, R., Gloghini, A., et al. (2002) · Human Pathology · doi:10.1053/hupa.2002.125372 · Cited by 57

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosisPreprint

Müller, H., Bracken, A. P., Vernell, R., Moroni, M. C., Christians, F. C., Grassilli, E., Prosperini, E., Vigo, E., Oliner, J. D., & Helin, K. (2001) · Genes & Development · doi:10.1101/gad.864201 · Cited by 752

Regulation and Activity of the Retinoblastoma Protein Family in Growth Factor-Deprived and TGFβ-Treated Keratinocytes

Belbrahem, A., Godden-Kent, D., & Mittnacht, S. (1996) · Experimental Cell Research · doi:10.1006/excr.1996.0178 · Cited by 8

Retinoblastoma/p107/p130 Pocket Proteins

Stengel, K. R., Thangavel, C., Solomon, D. A., Angus, S. P., Zheng, Y., & Knudsen, E. S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808740200 · Cited by 41

Tandem E2F Binding Sites in the Promoter of the p107 Cell Cycle Regulator Control p107 Expression and Its Cellular Functions

Burkhart, D. L., Wirt, S. E., Zmoos, A., Kareta, M. S., & Sage, J. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001003 · Cited by 38

E2F-4, a new member of the E2F transcription factor family, interacts with p107.Preprint

Ginsberg, D., Vairo, G., Chittenden, T., Xiao, Z. J., Xu, G., Wydner, K. L., DeCaprio, J. A., Lawrence, J. B., & Livingston, D. M. (1994) · Genes & Development · doi:10.1101/gad.8.22.2665 · Cited by 330