The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
The boundaries of the silenced HMR domain in Saccharomyces cerevisiae
Open accessAbstract
The chromosomes of eukaryotes are organized into structurally and functionally discrete domains that provide a mechanism to compact the DNA as well as delineate independent units of gene activity. It is believed that insulator/boundary elements separate these domains. Here we report the identification and characterization of boundary elements that flank the transcriptionally repressed HMR locus in the yeast Saccharomyces cerevisiae. Deletion of these boundary elements led to the spread of silenced chromatin, whereas the ectopic insertion of these elements between a silencer and a promoter blocked the repressive effects of the silencer on that promoter at HMR and at telomeres. Sequence analysis indicated that the boundary element contained a TY1 LTR, and a tRNA gene and mutational analysis has implicated the Smc proteins, which encode structural components of chromosomes, in boundary element function.
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Cites
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Cohesin mediates transcriptional insulation by CCCTC-binding factor
Wendt, K. S., Yoshida, K., Itoh, T., Bando, M., Koch, B., Schirghuber, E., Tsutsumi, S., Nagae, G., Ishihara, K., Mishiro, T., et al. (2008) · Nature · doi:10.1038/nature06634 · Cited by 1,193
Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms
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Cohesin relocation from sites of chromosomal loading to places of convergent transcription
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Dynamics of Replication-Independent Histone Turnover in Budding Yeast
Dion, M. F., Kaplan, T., Kim, M., Buratowski, S., Friedman, N., & Rando, O. J. (2007) · Science · doi:10.1126/science.1134053 · Cited by 556
Metadata
- Authors
- Donze, D., Adams, C. R., Rine, J., & Kamakaka, R. T.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1999-03-15
- Volume
- 13
- Issue
- 6
- Pages
- 698-708
- ISSN
- 0890-9369 (ISSN-L)
- OpenAlex
- W2102155883
- Cited by
- 373
- References
- 28
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Donze, D., Adams, C. R., Rine, J., & Kamakaka, R. T. (1999). The boundaries of the silenced HMR domain in Saccharomyces cerevisiae. Genes & Development. https://doi.org/10.1101/gad.13.6.698
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