The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Neural guidance molecules regulate vascular remodeling and vessel navigation
Open accessAbstract
The development of the embryonic blood vascular and lymphatic systems requires the coordinated action of several transcription factors and growth factors that target endothelial and periendothelial cells. However, according to recent studies, the precise “wiring” of the vascular system does not occur without an ordered series of guidance decisions involving several molecules initially discovered for axons in the nervous system, including ephrins, netrins, slits, and semaphorins. Here, we summarize the new advances in our understanding of the roles of these axonal pathfinding molecules in vascular remodeling and vessel guidance, indicating that neuronal axons and vessel sprouts use common molecular mechanisms for navigation in the body.
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Cites
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
Gerhardt, H., Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D., et al. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302047 · Cited by 2,894
Self-citationSondell, M., Lundborg, G., & Kanje, M. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-14-05731.1999 · Cited by 750 · cited 2×
“In vitro experiments have shown that VEGF/VEGFR-2 signaling can promote axonal outgrowth (Sondell et al. 1999), although the normality of mice deficient of VEGFR-2 in neuronal cells suggests that VEGF/VEGFR-2 signaling has no significant autocrine role in CNS development (Haigh et al.”
BackgroundGale, N. W., Dominguez, M. G., Noguera, I., Pan, L., Hughes, V., Valenzuela, D. M., Murphy, A. J., Adams, N. C., Lin, H. C., Holash, J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407290101 · Cited by 600
Cited by
Signal transduction by vascular endothelial growth factor receptors
Koch, S., Tugues, S., Li, X., Gualandi, L., & Claesson-Welsh, L. (2011) · Biochemical Journal · doi:10.1042/bj20110301 · Cited by 1,635
Dynamics of endothelial cell behavior in sprouting angiogenesis
Eilken, H. M., & Adams, R. H. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2010.08.010 · Cited by 561
Resistance Mechanisms to Anti-angiogenic Therapies in Cancer
Haibe, Y., Kreidieh, M., El Hajj, H., Khalifeh, I., Mukherji, D., Temraz, S., & Shamseddine, A. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00221 · Cited by 396
Grote, D., Souabni, A., Busslinger, M., & Bouchard, M. (2006) · Development · doi:10.1242/dev.02184 · Cited by 351
Peripheral changes in endometriosis-associated pain
Morotti, M., Vincent, K., Brawn, J., Zondervan, K. T., & Becker, C. M. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu021 · Cited by 198
Metadata
- Authors
- Eichmann, A., Makinen, T., & Alitalo, K.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2005-05-01
- Volume
- 19
- Issue
- 9
- Pages
- 1013-1021
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W1999771190
- Cited by
- 245
- References
- 3
- Type
- posted content
- Language
- en
- Open access
- diamond
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